Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Hung, Ming Szu ^a,b,c   Xu, Zhidong ^a   Lin, Yu Ching ^b,c   Mao, Jian Hua ^d   Yang, Cheng Ta ^b,c   Chang, Pey Jium ^c   Jablons, David M ^a   You, Liang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; CASEIN KINASE II; HEMATEIN; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE INHIBITOR; RADIOISOTOPE; SERINE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; HEMATOXYLIN; PROTEIN KINASE INHIBITOR;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL LABELING; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; DRUG BINDING; DRUG IDENTIFICATION; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG UPTAKE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE COMPLEX; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; WESTERN BLOTTING; CELL GROWTH; CELL STRAIN HCT116; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; ENZYMOLOGY; HELA CELL; LUNG TUMOR; METABOLISM; NEOPLASM; PATHOLOGY; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CASEIN KINASE II; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HCT116 CELLS; HELA CELLS; HEMATOXYLIN; HUMANS; LUNG NEOPLASMS; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; SUBSTRATE SPECIFICITY;

EID: 67649289884     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-135     Document Type: Article

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