Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90

Journal of Biological Chemistry

Volumn 283, Issue 30, 2008, Pages 21170-21178

  Cunningham, Christian N ^b   Krukenberg, Kristin A ^b   Agard, David A ^a,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DATA STRUCTURES; FLOW INTERACTIONS; GRID COMPUTING; HYDROLYSIS; HYDROPHOBICITY; MONOMERS; NUCLEIC ACIDS; NUCLEOTIDES; PLANTS (BOTANY); PORT TERMINALS;

ACTIVE CONFORMATIONS; ACTIVE SITES; ATP HYDROLYSES; ATPASE ACTIVITIES; ATPASES; BLOCK DOMAINS; CONFORMATIONAL CHANGES; COOPERATIVITY; DIMER FORMATIONS; DO-MAINS; HETERO DIMERS; HYDROPHOBIC RESIDUES; INTERDOMAIN INTERACTIONS; INTRA DOMAINS; MOLECULAR CHAPERONES; MOLECULAR MECHANISMS; PROTEIN DATA BANKS; STRUCTURAL CHANGES; TERMINAL DOMAINS;

CONFORMATIONS;

ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; ARGININE; DIMER; HEAT SHOCK PROTEIN 90; HETERODIMER; MONOMER; PHOSPHATE; ADENOSINE TRIPHOSPHATASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN INTERACTION; X RAY CRYSTALLOGRAPHY; BINDING SITE; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HYDROLYSIS; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HSP90 HEAT-SHOCK PROTEINS; HYDROLYSIS; MODELS, BIOLOGICAL; MOLECULAR CONFORMATION; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE;

EID: 51049093018     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800046200     Document Type: Article

References (32)

1. Picard, D. (2002) CMLS Cell Mol. Life Sci. 59, 1640-1648
2. Young, J. C., Hoogenraad, N. J., and Hartl, F. U. (2003) Cell 112, 41-50
3. Pratt, W. B., and Toft, D. O. (1997) Endocr. Rev. 18, 306-360
4. Freeman, B. C., and Yamamoto, K. R. (2002) Science 296, 2232-2235
5. Pearl, L. H., and Prodromou, C. (2006) Annu. Rev. Biochem. 75, 271-294
6. McClellan, A. J., Xia, Y., Deutschbauer, A. M., Davis, R. W., Gerstein, M., and Frydman, J. (2007) Cell 131, 121-135
7. Harris, S. F., Shiau, A. K., and Agard, D. A. (2004) Structure (Camb.) 12, 1087-1097
8. Shiau, A. K., Harris, S. F., Southworth, D. R., and Agard, D. A. (2006) Cell 127, 329-340
9. Ali, M. M., Roe, S. M., Vaughan, C. K., Meyer, P., Panaretou, B., Piper, P. W., Prodromou, C., and Pearl, L. H. (2006) Nature 440, 1013-1017
10. Neckers, L., and Ivy, S. P. (2003) Curr. Opin. Oncol. 15, 419-424
11. Maloney, A., and Workman, P. (2002) Expert Opin. Biol. Ther. 2, 3-24
12. Neckers, L., and Neckers, K. (2002) Expert Opin. Emerg. Drugs. 7, 277-288
13. Prodromou, C., Panaretou, B., Chohan, S., Siligardi, G., O'Brien, R., Ladbury, J. E., Roe, S. M., Piper, P. W., and Pearl, L. H. (2000) EMBO J. 19, 4383-4392
14. Richter, K., Muschler, P., Hainzl, O., and Buchner, J. (2001) J. Biol. Chem. 276, 33689-33696
15. Panaretou, B., Prodromou, C., Roe, S. M., O'Brien, R., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1998) EMBO J. 17, 4829-4836
16. Dutta, R., and Inouye, M. (2000) Trends Biochem. Sci. 25, 24-28
17. Meyer, P., Prodromou, C., Hu, B., Vaughan, C., Roe, S. M., Panaretou, B., Piper, P. W., and Pearl, L. H. (2003) Mol. Cell 11, 647-658
18. McLaughlin, S. H., Ventouras, L. A., Lobbezoo, B., and Jackson, S. E. (2004) J. Mol. Biol. 344, 813-826
19. Wegele, H., Muschler, P., Bunck, M., Reinstein, J., and Buchner, J. (2003) J. Biol. Chem. 278, 39303-39310
20. Richter, K., Walter, S., and Buchner, J. (2004) J. Mol. Biol. 342, 1403-1413
21. Felts, S. J., Owen, B. A., Nguyen, P., Trepel, J., Donner, D. B., and Toft, D. O. (2000) J. Biol. Chem. 275, 3305-3312
22. Svergun, D. I. (1992) J. Appl. Crystallogr. 25, 495-503
23. Konarev, P. V., Volkov, V. V., Sokolova, A. V., Koch, M. H. J., and Svergun, D. I. (2003) J. Appl. Crystallogr. 36, 1277-1282
24. Nathan, D. F., and Lindquist, S. (1995) Mol. Cell. Biol. 15, 3917-3925
25. Vaughan, C. K., Gohlke, U., Sobott, F., Good, V. M., Ali, M. M., Prodromou, C., Robinson, C. V., Saibil, H. R., and Pearl, L. H. (2006) Mol. Cell 23, 697-707
26. Roe, S. M., Ali, M. M., Meyer, P., Vaughan, C. K., Panaretou, B., Piper, P. W., Prodromou, C., and Pearl, L. H. (2004) Cell 116, 87-98
27. McLaughlin, S. H., Sobott, F., Yao, Z. P., Zhang, W., Nielsen, P. R., Grossmann, J. G., Laue, E. D., Robinson, C. V., and Jackson, S. E. (2006) J. Mol. Biol. 356, 746-758
28. Richter, K., Muschler, P., Hainzl, O., Reinstein, J., and Buchner, J. (2003) J. Biol. Chem. 278, 10328-10333
29. Siligardi, G., Panaretou, B., Meyer, P., Singh, S., Woolfson, D. N., Piper, P. W., Pearl, L. H., and Prodromou, C. (2002) J. Biol. Chem. 277, 20151-20159
30. Zhang, W., Hirshberg, M., McLaughlin, S. H., Lazar, G. A., Grossmann, J. G., Nielsen, P. R., Sobott, F., Robinson, C. V., Jackson, S. E., and Laue, E. D. (2004) J. Mol. Biol. 340, 891-907
31. Meyer, P., Prodromou, C., Liao, C., Hu, B., Mark Roe, S., Vaughan, C. K., Vlasic, I., Panaretou, B., Piper, P. W., and Pearl, L. H. (2004) EMBO J. 23, 511-519
32. Siligardi, G., Hu, B., Panaretou, B., Piper, P. W., Pearl, L. H., and Prodromou, C. (2004) J. Biol. Chem. 279, 51989-51998