-
1
-
-
14944375587
-
Immunology of hepatitis B virus and hepatitis C virus infection
-
DOI 10.1038/nri1573
-
Rehermann B, Nascimbeni M,. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 2005; 5: 215-229. (Pubitemid 40364823)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.3
, pp. 215-229
-
-
Rehermann, B.1
Nascimbeni, M.2
-
2
-
-
58649096155
-
2-Year GLOBE trial results: Telbivudine is superior to lamivudine in patients with chronic hepatitis B
-
Liaw YF, Gane E, Leung N, et al,. 2-Year GLOBE trial results: telbivudine is superior to lamivudine in patients with chronic hepatitis B. Gastroenterology 2009; 136: 486-495.
-
(2009)
Gastroenterology
, vol.136
, pp. 486-495
-
-
Liaw, Y.F.1
Gane, E.2
Leung, N.3
-
3
-
-
2642580655
-
Natural history of hepatitis B e antigen to antibody seroconversion in patients with normal serum aminotransferase levels
-
DOI 10.1016/j.amjmed.2003.12.040, PII S0002934304001469
-
Chu CM, Hung SJ, Lin J, Tai DI, Liaw YF,. Natural history of hepatitis B e antigen to antibody seroconversion in patients with normal serum aminotransferase levels. Am J Med 2004; 116: 829-834. (Pubitemid 38721324)
-
(2004)
American Journal of Medicine
, vol.116
, Issue.12
, pp. 829-834
-
-
Chu, C.-M.1
Hung, S.-J.2
Lin, J.3
Tai, D.-I.4
Liaw, Y.-F.5
-
4
-
-
33751514752
-
Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma
-
Lin SM, Yu ML, Lee CM, et al,. Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma. J Hepatol 2007; 46 (1): 45-52.
-
(2007)
J Hepatol
, vol.46
, Issue.1
, pp. 45-52
-
-
Lin, S.M.1
Yu, M.L.2
Lee, C.M.3
-
5
-
-
0029893146
-
Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B
-
DOI 10.1056/NEJM199605303342202
-
Niederau C, Heintges T, Lange S, et al,. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N Engl J Med 1996; 334: 1422-1427. (Pubitemid 26157437)
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.22
, pp. 1422-1427
-
-
Niederau, C.1
Heintges, T.2
Lange, S.3
Goldmann, G.4
Niederau, C.M.5
Mohr, L.6
Haussinger, D.7
-
6
-
-
84984555343
-
Hepatitis B e antigen and the risk of hepatocellular carcinoma
-
Yang HI, Lu SN, Liaw YF, et al,. Hepatitis B e antigen and the risk of hepatocellular carcinoma. N Engl J Med 2002; 347: 168-174.
-
(2002)
N Engl J Med
, vol.347
, pp. 168-174
-
-
Yang, H.I.1
Lu, S.N.2
Liaw, Y.F.3
-
7
-
-
51049107683
-
Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2008 update
-
Liaw YF, Leung N, Kao J-H, et al,. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int 2008; 2: 263-283.
-
(2008)
Hepatol Int
, vol.2
, pp. 263-283
-
-
Liaw, Y.F.1
Leung, N.2
Kao, J.-H.3
-
8
-
-
0037468421
-
Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
-
DOI 10.1056/NEJMoa020681
-
Marcellin P, Chang TT, Lim SG, et al,. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003; 348: 808-816. (Pubitemid 36245757)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.9
, pp. 808-816
-
-
Marcellin, P.1
Chang, T.-T.2
Lim, S.G.3
Tong, M.J.4
Sievert, W.5
Shiffman, M.L.6
Jeffers, L.7
Goodman, Z.8
Wulfsohn, M.S.9
Xiong, S.10
Fry, J.11
Brosgart, C.L.12
-
9
-
-
33745921497
-
A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B
-
Zeng MD, Mao YM, Yao GB, et al,. A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B. Hepatology 2006; 44: 108-116.
-
(2006)
Hepatology
, vol.44
, pp. 108-116
-
-
Zeng, M.D.1
Mao, Y.M.2
Yao, G.B.3
-
10
-
-
33644818518
-
A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
-
DOI 10.1056/NEJMoa051285
-
Chang TT, Gish RG, Man R, et al,. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 2006; 354 (10): 1001-1010. (Pubitemid 43357804)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.10
, pp. 1001-1010
-
-
Chang, T.-T.1
Gish, R.G.2
De Man, R.3
Gadano, A.4
Sollano, J.5
Chao, Y.-C.6
Lok, A.S.7
Han, K.-H.8
Goodman, Z.9
Zhu, J.10
Cross, A.11
DeHertogh, D.12
Wilber, R.13
Colonno, R.14
Apelian, D.15
-
11
-
-
57149089345
-
Efficacy and safety of entecavir compared to lamivudine in nucleoside-naïve patients with chronic hepatitis B: A randomized double-blind trial in China
-
Yao GB, Chen CW, Lu WL, et al,. Efficacy and safety of entecavir compared to lamivudine in nucleoside-naïve patients with chronic hepatitis B: a randomized double-blind trial in China. Hepatol Int 2007; 1: 365-372.
-
(2007)
Hepatol Int
, vol.1
, pp. 365-372
-
-
Yao, G.B.1
Chen, C.W.2
Lu, W.L.3
-
12
-
-
57349095400
-
Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
-
Marcellin P, Heathcote EJ, Buti M, et al,. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N Engl J Med 2008; 359 (23): 2442-2455.
-
(2008)
N Engl J Med
, vol.359
, Issue.23
, pp. 2442-2455
-
-
Marcellin, P.1
Heathcote, E.J.2
Buti, M.3
-
13
-
-
21244447705
-
Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
-
DOI 10.1056/NEJMoa043470
-
Lau GK, Piratvisuth T, Luo KX, et al,. Peginterferon alfa-2a HBeAg-positive chronic hepatitis B study group. Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med 2005; 352 (26): 2682-2695. (Pubitemid 41007823)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.26
, pp. 2682-2695
-
-
Lau, G.K.K.1
Piratvisuth, T.2
Kang, X.L.3
Marcellin, P.4
Thongsawat, S.5
Cooksley, G.6
Gane, E.7
Fried, M.W.8
Wan, C.C.9
Seung, W.P.10
Wen, Y.C.11
Berg, T.12
Flisiak, R.13
McCloud, P.14
Pluck, N.15
-
14
-
-
39549113880
-
Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial
-
DOI 10.1002/hep.22075
-
Hou J, Yin YK, Xu D, et al,. Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: results at 1 year of a randomized, double-blind trial. Hepatology 2008; 47: 447-454. (Pubitemid 351280712)
-
(2008)
Hepatology
, vol.47
, Issue.2
, pp. 447-454
-
-
Hou, J.1
Yin, Y.-K.2
Xu, D.3
Tan, D.4
Niu, J.5
Zhou, X.6
Wang, Y.7
Zhu, L.8
He, Y.9
Ren, H.10
Wan, M.11
Chen, G.12
Wu, S.13
Chen, Y.14
Xut, J.15
Wang, Q.16
Wei, L.17
Chao, G.18
Constance, B.F.19
Harb, G.20
Brown, N.A.21
Jia, J.22
more..
-
15
-
-
36349031420
-
Efficacy of telbivudine vs lamivudine at 2 years in patients with HBeAg-positive chronic hepatitis B who are eligible for treatment based on guidelines
-
Rasenack J, Poynard T, Lai C-L, et al,. Efficacy of telbivudine vs lamivudine at 2 years in patients with HBeAg-positive chronic hepatitis B who are eligible for treatment based on guidelines. J Hepatol 2007; 46 (Suppl. 1): S195.
-
(2007)
J Hepatol
, vol.46
, Issue.SUPPL. 1
-
-
Rasenack, J.1
Poynard, T.2
Lai, C.-L.3
-
16
-
-
34447125265
-
Two-year results of a phase III comparative trial of telbivudine vs lamivudine in Chinese patients
-
Jia JD, Hou JL, Yin YK, et al,. Two-year results of a phase III comparative trial of telbivudine vs lamivudine in Chinese patients. J Hepatol 2007; 46 (Suppl. 1): S189.
-
(2007)
J Hepatol
, vol.46
, Issue.SUPPL. 1
-
-
Jia, J.D.1
Hou, J.L.2
Yin, Y.K.3
-
17
-
-
84872611883
-
Lamivudine versus telbivudine in the treatment of chronic hepatitis B: A systematic review and meta-analysis
-
Jiang H, Wang J, Zhao W,. Lamivudine versus telbivudine in the treatment of chronic hepatitis B: a systematic review and meta-analysis. Eur J Clin Microbiol Infect Dis 2013; 32 (1): 11-18.
-
(2013)
Eur J Clin Microbiol Infect Dis
, vol.32
, Issue.1
, pp. 11-18
-
-
Jiang, H.1
Wang, J.2
Zhao, W.3
-
18
-
-
0037366499
-
Hepatitis flares and hepatitis B e antigen seroconversion: Implication in anti-hepatitis B virus therapy
-
Liaw YF,. Hepatitis flares and hepatitis B e antigen seroconversion: implication in anti-hepatitis B virus therapy. J Gastroenterol Hepatol 2003; 18: 246-252.
-
(2003)
J Gastroenterol Hepatol
, vol.18
, pp. 246-252
-
-
Liaw, Y.F.1
-
19
-
-
0032869876
-
Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B
-
DOI 10.1002/hep.510300313
-
Chien RN, Liaw YF, Atkins M,. Asian Hepatitis Lamivudine Trial Group. Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B. Hepatology 1999; 30 (3): 770-774. (Pubitemid 29409422)
-
(1999)
Hepatology
, vol.30
, Issue.3
, pp. 770-774
-
-
Chien, R.-N.1
Liaw, Y.-F.2
Atkins, M.3
-
20
-
-
84874635879
-
Prolonged efficacy and safety of 4 years continuous telbivudine treatment in chronic hepatitis B (CHB) patients from GLOBE and 015 studies
-
March 25-28, Beijing, China
-
Jia J, Gane E, Wang YM, et al,. Prolonged efficacy and safety of 4 years continuous telbivudine treatment in chronic hepatitis B (CHB) patients from GLOBE and 015 studies. Poster FP-090 presented at the 20th Asian Pacific Association for the Study of the Liver (APASL), March 25-28 2010, Beijing, China.
-
(2010)
Poster FP-090 Presented at the 20th Asian Pacific Association for the Study of the Liver (APASL)
-
-
Jia, J.1
Gane, E.2
Wang, Y.M.3
-
21
-
-
84860315818
-
Long-term telbivudine treatment with effective viral control results in resolution of liver fibrosis an inflammation which achieves long-term anti-viral goals in patients with chronic hepatitis B
-
Poster No. 1446 presented at the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, November 4-8, 2011
-
Hou J, Xu D, Shi G, et al,. Long-term telbivudine treatment with effective viral control results in resolution of liver fibrosis an inflammation which achieves long-term anti-viral goals in patients with chronic hepatitis B. Hepatol 2011b; 54 (4 Suppl.): 1048A. Poster No. 1446 presented at the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, November 4-8, 2011.
-
(2011)
Hepatol
, vol.54
, Issue.4 SUPPL.
-
-
Hou, J.1
Xu, D.2
Shi, G.3
-
22
-
-
84874639745
-
Telbivudine (LDT) plus peginterferon (PEGIFN) in HBeAg-positive chronic hepatitis B - Very potent antiviral efficacy but risk of peripheral neuropathy (PN)
-
Apr 14-18, Vienna, Austria
-
Marcellin P, Avila C, Wursthorn K, et al,. Telbivudine (LDT) plus peginterferon (PEGIFN) in HBeAg-positive chronic hepatitis B-very potent antiviral efficacy but risk of peripheral neuropathy (PN). Oral presentation at the 45th Annual Meeting of the European Association for the Study of the Liver (EASL), Apr 14-18 2010, Vienna, Austria.
-
(2010)
Oral Presentation at the 45th Annual Meeting of the European Association for the Study of the Liver (EASL)
-
-
Marcellin, P.1
Avila, C.2
Wursthorn, K.3
-
23
-
-
84874627842
-
1-year results of telbivudine roadmap study demonstrated maximizing antiviral efficacy and minimizing resistance in HBeAg positive chronic hepatitis B patients
-
FC01-01. Oral presentation at the 21st Conference of the Asian Pacific Association of the Study of the Liver (APASL), Feb 17-20 2011, Bangkok, Thailand
-
Piratvisuth T, Komolmit P, Tanwandee T, et al,. 1-year results of telbivudine roadmap study demonstrated maximizing antiviral efficacy and minimizing resistance in HBeAg positive chronic hepatitis B patients. Hepatol Int 2011; 5: 18-19. FC01-01. Oral presentation at the 21st Conference of the Asian Pacific Association of the Study of the Liver (APASL), Feb 17-20 2011, Bangkok, Thailand.
-
(2011)
Hepatol Int
, vol.5
, pp. 18-19
-
-
Piratvisuth, T.1
Komolmit, P.2
Tanwandee, T.3
-
24
-
-
84872009726
-
2-year results of telbivudine roadmap study verify the optimal efficacy and safety results in HBeAg positive chronic hepatitis B patients
-
Piratvisuth T, Komolmit P, Tanwandee T, et al,. 2-year results of telbivudine roadmap study verify the optimal efficacy and safety results in HBeAg positive chronic hepatitis B patients. J Hepatol 2012; 56 (Suppl. 2): S214.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Piratvisuth, T.1
Komolmit, P.2
Tanwandee, T.3
-
26
-
-
84863011075
-
A comparison of telbivudine and entecavir for chronic hepatitis B in real-world clinical practice
-
Tsai MC, Lee CM, Chiu KW, et al,. A comparison of telbivudine and entecavir for chronic hepatitis B in real-world clinical practice. J Antimicrob Chemother 2012; 67 (3): 696-699.
-
(2012)
J Antimicrob Chemother
, vol.67
, Issue.3
, pp. 696-699
-
-
Tsai, M.C.1
Lee, C.M.2
Chiu, K.W.3
-
27
-
-
0037381547
-
Durability of serologic response after lamivudine treatment of chronic hepatitis B
-
DOI 10.1053/jhep.2003.50117
-
Dienstag JL, Cianciara J, Karayalcin S, et al,. Durability of serologic response after lamivudine treatment of chronic hepatitis B. Hepatology 2003; 37 (4): 748-755. (Pubitemid 36397384)
-
(2003)
Hepatology
, vol.37
, Issue.4
, pp. 748-755
-
-
Dienstag, J.L.1
Cianciara, J.2
Karayalcin, S.3
Kowdley, K.V.4
Willems, B.5
Plisek, S.6
Woessner, M.7
Gardner, S.8
Schiff, E.9
-
28
-
-
0033797827
-
Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea
-
Song BC, Suh DJ, Lee HC, et al,. Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea. Hepatology 2000; 32 (4 Pt 1): 803-806.
-
(2000)
Hepatology
, vol.32
, Issue.4 PART 1
, pp. 803-806
-
-
Song, B.C.1
Suh, D.J.2
Lee, H.C.3
-
29
-
-
0036844794
-
Durability of lamivudine-induced HBeAg seroconversion for chronic hepatitis B patients with acute exacerbation
-
Lee CM, Ong GY, Lu SN, et al,. Durability of lamivudine-induced HBeAg seroconversion for chronic hepatitis B patients with acute exacerbation. J Hepatol 2002; 37 (5): 669-674.
-
(2002)
J Hepatol
, vol.37
, Issue.5
, pp. 669-674
-
-
Lee, C.M.1
Ong, G.Y.2
Lu, S.N.3
-
30
-
-
0142244873
-
Determinants for sustained HBeAg response to lamivudine therapy
-
Chien RN, Yeh CT, Tsai SL, et al,. Determinants for sustained HBeAg response to lamivudine therapy. Hepatology 2003; 38 (5): 1267-1273.
-
(2003)
Hepatology
, vol.38
, Issue.5
, pp. 1267-1273
-
-
Chien, R.N.1
Yeh, C.T.2
Tsai, S.L.3
-
31
-
-
4644298430
-
Sustained response after a 2-year course of lamivudine treatment of hepatitis B e antigen-negative chronic hepatitis B
-
DOI 10.1111/j.1365-2893.2004.00556.x
-
Fung SK, Wong F, Hussain M, et al,. Sustained response after a 2-year course of lamivudine treatment of hepatitis B e antigen-negative chronic hepatitis B. J Viral Hepat 2004; 11 (5): 432-438. (Pubitemid 39336224)
-
(2004)
Journal of Viral Hepatitis
, vol.11
, Issue.5
, pp. 432-438
-
-
Fung, S.K.1
Wong, F.2
Hussain, M.3
Lok, A.S.F.4
-
32
-
-
34249090519
-
Two-year lamivudine treatment for hepatitis B e antigen-negative chronic hepatitis B: A double-blind, placebo-controlled trial
-
Chan HL, Wang H, Niu J, et al,. Two-year lamivudine treatment for hepatitis B e antigen-negative chronic hepatitis B: a double-blind, placebo-controlled trial. Antivir Ther 2007; 12 (3): 345-353. (Pubitemid 46787979)
-
(2007)
Antiviral Therapy
, vol.12
, Issue.3
, pp. 345-353
-
-
Chan, H.L.-Y.1
Wang, H.2
Niu, J.3
Chim, A.M.-L.4
Sung, J.J.-Y.5
-
33
-
-
54249142122
-
Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment: Analysis of precore and basal core promoter mutants
-
Wu IC, Shiffman ML, Tong MJ, et al,. Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment: analysis of precore and basal core promoter mutants. Clin Infect Dis 2008; 47 (10): 1305-1311.
-
(2008)
Clin Infect Dis
, vol.47
, Issue.10
, pp. 1305-1311
-
-
Wu, I.C.1
Shiffman, M.L.2
Tong, M.J.3
-
34
-
-
21244455293
-
Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
-
DOI 10.1056/NEJMoa042957
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al,. Adefovir Dipivoxil 438 Study Group. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med 2005; 352 (26): 2673-2681. (Pubitemid 41007822)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.26
, pp. 2673-2681
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Jenny Heathcote, E.3
Chang, T.-T.4
Kitis, G.5
Rizzetto, M.6
Marcellin, P.7
Seng, G.L.8
Goodman, Z.9
Ma, J.10
Arterburn, S.11
Xiong, S.12
Currie, G.13
Brosgart, C.L.14
-
35
-
-
35649020315
-
Entecavir Therapy for up to 96 Weeks in Patients With HBeAg-Positive Chronic Hepatitis B
-
DOI 10.1053/j.gastro.2007.08.025, PII S0016508507014825
-
Gish RG, Lok AS, Chang TT, et al,. Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B. Gastroenterology 2007; 133 (5): 1437-1444. (Pubitemid 350029745)
-
(2007)
Gastroenterology
, vol.133
, Issue.5
, pp. 1437-1444
-
-
Gish, R.G.1
Lok, A.S.2
Chang, T.3
De Man, R.A.4
Gadano, A.5
Sollano, J.6
Han, K.7
Chao, Y.8
Lee, S.9
Harris, M.10
Yang, J.11
Colonno, R.12
Brett-Smith, H.13
-
36
-
-
58149316191
-
Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: The case for continuous antiviral therapy
-
Shouval D, Lai CL, Chang TT, et al,. Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: the case for continuous antiviral therapy. J Hepatol 2009; 50 (2): 289-295.
-
(2009)
J Hepatol
, vol.50
, Issue.2
, pp. 289-295
-
-
Shouval, D.1
Lai, C.L.2
Chang, T.T.3
-
37
-
-
65449117946
-
Hepatitis B virus surface antigen levels: A guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B
-
Brunetto MR, Moriconi F, Bonino F, et al,. Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B. Hepatology 2009; 49: 1141-1145.
-
(2009)
Hepatology
, vol.49
, pp. 1141-1145
-
-
Brunetto, M.R.1
Moriconi, F.2
Bonino, F.3
-
38
-
-
61849155116
-
On-treatment HBsAg decline during peginterferon alfa-2a(40KD) lamivudine in patients with HBeAg-positive CHB as a potential predictor of durable off treatment response
-
Lau GK, Marcellin P, Brunetto M, Button T, Batria R,. On-treatment HBsAg decline during peginterferon alfa-2a(40KD) lamivudine in patients with HBeAg-positive CHB as a potential predictor of durable off treatment response. Hepatology 2008; 48 (Suppl. 1): 714A.
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Lau, G.K.1
Marcellin, P.2
Brunetto, M.3
Button, T.4
Batria, R.5
-
39
-
-
65449123444
-
Early serum HBsAg drop: A strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients
-
Moucari R, Mackiewicz V, Lada O, et al,. Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. Hepatology 2009; 49: 1151-1157.
-
(2009)
Hepatology
, vol.49
, pp. 1151-1157
-
-
Moucari, R.1
Mackiewicz, V.2
Lada, O.3
-
40
-
-
67349168493
-
High rates of HBsAg seroconversion in HBeAg- positive chronic hepatitis B patients responding to interferon: A long-term follow-up study
-
Moucari R, Korevaar A, Lada O, et al,. High rates of HBsAg seroconversion in HBeAg- positive chronic hepatitis B patients responding to interferon: a long-term follow-up study. J Hepatol 2009; 50: 1084-1092.
-
(2009)
J Hepatol
, vol.50
, pp. 1084-1092
-
-
Moucari, R.1
Korevaar, A.2
Lada, O.3
-
41
-
-
33748929265
-
Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
-
DOI 10.1002/hep.21282
-
Wursthorn K, Lutgehetmann M, Dandri M, et al,. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. Hepatology 2006; 44: 675-684. (Pubitemid 44433724)
-
(2006)
Hepatology
, vol.44
, Issue.3
, pp. 675-684
-
-
Wursthorn, K.1
Lutgehetmann, M.2
Dandri, M.3
Volz, T.4
Buggisch, P.5
Zollner, B.6
Longerich, T.7
Schirmacher, P.8
Metzler, F.9
Zankel, M.10
Fischer, C.11
Currie, G.12
Brosgart, C.13
Petersen, J.14
-
42
-
-
77956592924
-
Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients
-
Wursthorn K, Jung M, Riva A, et al,. Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients. Hepatology 2010; 52: 1611-1620.
-
(2010)
Hepatology
, vol.52
, pp. 1611-1620
-
-
Wursthorn, K.1
Jung, M.2
Riva, A.3
-
43
-
-
15944370447
-
Viral dynamics for LDT (telbivudine)-treated hepatitis B patients: High degree of initial inhibition with dose-dependent second-phase HBV clearance suggests a new model for HBV dynamics
-
Neumann AU, Zhou XJ, Boehme RE, et al,. Viral dynamics for LDT (telbivudine)-treated hepatitis B patients: high degree of initial inhibition with dose-dependent second-phase HBV clearance suggests a new model for HBV dynamics. Hepatology 2004; 40 (Suppl. 1): 246A.
-
(2004)
Hepatology
, vol.40
, Issue.SUPPL. 1
-
-
Neumann, A.U.1
Zhou, X.J.2
Boehme, R.E.3
-
44
-
-
0036022843
-
The influence of baseline characteristics on viral dynamic parameters in chronic hepatitis B patients treated with lamivudine
-
DOI 10.1016/S0168-8278(02)00113-7, PII S0168827802001137
-
Wolters LM, Hansen BE, Niesters HG, et al,. The influence of baseline characteristics on viral dynamic parameters in chronic hepatitis B patients treated with lamivudine. J Hepatol 2002; 37 (2): 253-258. (Pubitemid 34833088)
-
(2002)
Journal of Hepatology
, vol.37
, Issue.2
, pp. 253-258
-
-
Wolters, L.M.M.1
Hansen, B.E.2
Niesters, H.G.M.3
Levi-Drummer, R.S.4
Neumann, A.U.5
Schalm, S.W.6
De Man, R.A.7
-
45
-
-
23044436704
-
Hepatitis B viral kinetics: A dynamic puzzle still to be resolved
-
DOI 10.1002/hep.20831
-
Neumann AU, Hepatitis B,. viral kinetics: a dynamic puzzle still to be resolved. Hepatology 2005; 42 (2): 249-254. (Pubitemid 41061074)
-
(2005)
Hepatology
, vol.42
, Issue.2
, pp. 249-254
-
-
Neumann, A.U.1
-
46
-
-
0032475822
-
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-α therapy
-
DOI 10.1126/science.282.5386.103
-
Neumann AU, Lam NP, Dahari H, et al,. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science 1998 2; 282 (5386): 103-107. (Pubitemid 28471138)
-
(1998)
Science
, vol.282
, Issue.5386
, pp. 103-107
-
-
Neumann, A.U.1
Lam, N.P.2
Dahari, H.3
Gretch, D.R.4
Wiley, T.E.5
Layden, T.J.6
Perelson, A.S.7
-
47
-
-
0037432787
-
Requirement for CD4 T cell help in generating functional CD8 T cell memory
-
DOI 10.1126/science.1082305
-
Shedlock DJ, Shen H,. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003; 300 (5617): 337-339. (Pubitemid 36433726)
-
(2003)
Science
, vol.300
, Issue.5617
, pp. 337-339
-
-
Shedlock, D.J.1
Shen, H.2
-
48
-
-
84856226311
-
Expanding roles for CD4â T cells in immunity to viruses
-
Swain SL, McKinstry KK, Strutt TM,. Expanding roles for CD4â T cells in immunity to viruses. Nat Rev Immunol 2012; 12 (2): 136-148.
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.2
, pp. 136-148
-
-
Swain, S.L.1
McKinstry, K.K.2
Strutt, T.M.3
-
50
-
-
0033027690
-
Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection
-
Lin SM, Sheen IS, Chien RN, et al,. Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection. Hepatology 1999; 29 (3): 971-975.
-
(1999)
Hepatology
, vol.29
, Issue.3
, pp. 971-975
-
-
Lin, S.M.1
Sheen, I.S.2
Chien, R.N.3
-
51
-
-
51349132036
-
Programmed death 1expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion
-
Evans A, Riva A, Cooksley H, et al,. Programmed death 1expression during antiviral treatment of chronic hepatitis B: impact of hepatitis B e-antigen seroconversion. Hepatology 2008; 48: 759-769.
-
(2008)
Hepatology
, vol.48
, pp. 759-769
-
-
Evans, A.1
Riva, A.2
Cooksley, H.3
-
52
-
-
79951951194
-
Dynamic changes of Thl/Th2 type cytokines in peripheral blood of patients with hepatitis B e antigen positive chronic hepatitis B treated with telbivudine
-
(in Chinese)
-
Zhang L, Zhang DZ, Chen M, et al,. Dynamic changes of Thl/Th2 type cytokines in peripheral blood of patients with hepatitis B e antigen positive chronic hepatitis B treated with telbivudine. Chin J Hepatol 2009; 17 (3): 175-179. (in Chinese).
-
(2009)
Chin J Hepatol
, vol.17
, Issue.3
, pp. 175-179
-
-
Zhang, L.1
Zhang, D.Z.2
Chen, M.3
-
53
-
-
77749315681
-
Telbivudine preserves Th1 cytokine and inhibits Th2 cytokine production in MHV-3 induced viral hepatitis model
-
Wu Z, Yan W, Guo W, et al,. Telbivudine preserves Th1 cytokine and inhibits Th2 cytokine production in MHV-3 induced viral hepatitis model. J Viral Hepatitis 2010; 17 (Suppl. 1): 24-33.
-
(2010)
J Viral Hepatitis
, vol.17
, Issue.SUPPL. 1
, pp. 24-33
-
-
Wu, Z.1
Yan, W.2
Guo, W.3
-
54
-
-
33745323050
-
+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
-
Xu D, Fu J, Jin L, et al,. Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 2006; 177 (1): 739-747. (Pubitemid 43939189)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 739-747
-
-
Xu, D.1
Fu, J.2
Jin, L.3
Zhang, H.4
Zhou, C.5
Zou, Z.6
Zhao, J.-M.7
Zhang, B.8
Shi, M.9
Ding, X.10
Tang, Z.11
Fu, Y.-X.12
Wang, F.-S.13
-
55
-
-
77955291814
-
The effect of telbivudine on peripheral blood CD4+CD25+ regulatory T cells and its significance in patients with chronic hepatitis B
-
(in Chinese)
-
Pan XC, Yang F, Cheng M, et al,. The effect of telbivudine on peripheral blood CD4+CD25+ regulatory T cells and its significance in patients with chronic hepatitis B. Chin J Hepatol 2008; 16 (12): 885-888. (in Chinese)
-
(2008)
Chin J Hepatol
, vol.16
, Issue.12
, pp. 885-888
-
-
Pan, X.C.1
Yang, F.2
Cheng, M.3
-
56
-
-
84874621958
-
The combined frequencies of baseline Tregs and NK cells predicted HBV DNA negativity in telbivudine treated HBeAg-positive chronic hepatitis B patients
-
Chen T, Yan WM, Ding L, et al,. The combined frequencies of baseline Tregs and NK cells predicted HBV DNA negativity in telbivudine treated HBeAg-positive chronic hepatitis B patients. Hepatology 2011; 54 (4 Suppl.): 1011A.
-
(2011)
Hepatology
, vol.54
, Issue.4 SUPPL.
-
-
Chen, T.1
Yan, W.M.2
Ding, L.3
-
57
-
-
84863011093
-
Inhibition of viral replication downregulates CD4 + CD25(high) regulatory T cells and programmed death-ligand 1 in chronic hepatitis B
-
Nan XP, Zhang Y, Yu HT, et al,. Inhibition of viral replication downregulates CD4 + CD25(high) regulatory T cells and programmed death-ligand 1 in chronic hepatitis B. Viral Immunol 2012; 25 (1): 21-28.
-
(2012)
Viral Immunol
, vol.25
, Issue.1
, pp. 21-28
-
-
Nan, X.P.1
Zhang, Y.2
Yu, H.T.3
-
58
-
-
84861078273
-
Effects of telbivudine treatment on the circulating CD4(+) T-Cell subpopulations in chronic hepatitis B patients
-
doi: 10.1155/2012/789859 Article ID 789859
-
Zheng Y, Huang Z, Chen X, et al,. Effects of telbivudine treatment on the circulating CD4(+) T-Cell subpopulations in chronic hepatitis B patients. Mediators Inflamm vol. 2012, Article ID 789859: 9, 2012. doi: 10.1155/2012/789859.
-
(2012)
Mediators Inflamm
, vol.2012
, pp. 9
-
-
Zheng, Y.1
Huang, Z.2
Chen, X.3
-
59
-
-
33847406557
-
+ T lymphocytes in the liver
-
Maier H, Isogawa M, Freeman GJ, Chisari FV,. PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8 + T lymphocytes in the liver. J Immunol 2007; 178 (5): 2714-2720. (Pubitemid 46333147)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2714-2720
-
-
Maier, H.1
Isogawa, M.2
Freeman, G.J.3
Chisari, F.V.4
-
60
-
-
35648968689
-
PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
-
DOI 10.1016/j.molimm.2007.07.038, PII S0161589007006736
-
Peng G, Li S, Wu W, Tan X, Chen Y, Chen Z,. PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients. Mol Immunol 2008; 45 (4): 963-970. (Pubitemid 350019503)
-
(2008)
Molecular Immunology
, vol.45
, Issue.4
, pp. 963-970
-
-
Peng, G.1
Li, S.2
Wu, W.3
Tan, X.4
Chen, Y.5
Chen, Z.6
-
61
-
-
75149117314
-
Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B
-
Fisicaro P, Valdatta C, Massari M, Loggi E, Biasini E, Sacchelli L,. Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B. Gastroenterology 2010; 138 (2): 682-693.
-
(2010)
Gastroenterology
, vol.138
, Issue.2
, pp. 682-693
-
-
Fisicaro, P.1
Valdatta, C.2
Massari, M.3
Loggi, E.4
Biasini, E.5
Sacchelli, L.6
-
62
-
-
84862801307
-
High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B
-
Ma SW, Huang X, Li YY, et al,. High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B. J Hepatol 2012; 56 (4): 775-781.
-
(2012)
J Hepatol
, vol.56
, Issue.4
, pp. 775-781
-
-
Ma, S.W.1
Huang, X.2
Li, Y.Y.3
-
63
-
-
79961151793
-
Programmed death-1 (PD-1) and PD-L1 expression during antiviral treatment of chronic hepatitis B. Chinese
-
Xie DY, Lin BL, Chen FJ, et al,. Programmed death-1 (PD-1) and PD-L1 expression during antiviral treatment of chronic hepatitis B. Chinese. Chung Hua Kan Tsang Ping Tsa Chih 2010; 18 (9): 646-650.
-
(2010)
Chung Hua Kan Tsang Ping Tsa Chih
, vol.18
, Issue.9
, pp. 646-650
-
-
Xie, D.Y.1
Lin, B.L.2
Chen, F.J.3
-
64
-
-
18644370174
-
high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help
-
Fuller MJ, Hildeman DA, Sabbaj S, et al,. Cutting edge: emergence of CD127 high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. J Immunol 2005; 174 (10): 5926-5930. (Pubitemid 40663777)
-
(2005)
Journal of Immunology
, vol.174
, Issue.10
, pp. 5926-5930
-
-
Fuller, M.J.1
Hildeman, D.A.2
Sabbaj, S.3
Gaddis, D.E.4
Tebo, A.E.5
Shang, L.6
Goepfert, P.A.7
Zajac, A.J.8
-
65
-
-
20044382810
-
+ T cells in HIV-infected individuals
-
Paiardini M, Cervasi B, Albrecht H, et al,. Loss of CD127 expression defines an expansion of effector CD8 T cells in HIV-infected individuals. J Immunol 2005; 174 (5): 2900-2909. (Pubitemid 40279708)
-
(2005)
Journal of Immunology
, vol.174
, Issue.5
, pp. 2900-2909
-
-
Paiardini, M.1
Cervasi, B.2
Albrecht, H.3
Muthukumar, A.4
Dunham, R.5
Gordon, S.6
Radziewicz, H.7
Piedimonte, G.8
Magnani, M.9
Montroni, M.10
Kaech, S.M.11
Weintrob, A.12
Altman, J.B.13
Sodora, D.L.14
Feinberg, M.B.15
Silvestri, G.16
-
66
-
-
2142730100
-
Central memory and effector memory T cell subsets: Function, generation, and maintenance
-
DOI 10.1146/annurev.immunol.22.012703.104702
-
Sallusto F, Geginat J, Lanzavecchia A,. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Re Immunol 2004; 22: 745-763. (Pubitemid 38680440)
-
(2004)
Annual Review of Immunology
, vol.22
, pp. 745-763
-
-
Sallusto, F.1
Geginat, J.2
Lanzavecchia, A.3
-
67
-
-
34548683483
-
+ T Cell Differentiation during Viral Infection
-
DOI 10.1016/j.immuni.2007.08.007, PII S1074761307004104
-
Kaech SM, Wherry EJ,. Heterogeneity and cell-fate decisions in effector and memory CD8 T cell differentiation during viral infection. Immunity 2007; 27 (3): 393-405. (Pubitemid 47418674)
-
(2007)
Immunity
, vol.27
, Issue.3
, pp. 393-405
-
-
Kaech, S.M.1
Wherry, E.J.2
-
68
-
-
77956465395
-
Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment
-
Lv GC, Ying LJ, Ma WJ, et al,. Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment. Virology Journal 2010; 7: 207.
-
(2010)
Virology Journal
, vol.7
, pp. 207
-
-
Lv, G.C.1
Ying, L.J.2
Ma, W.J.3
-
69
-
-
79957523611
-
Effect of telbivudine therapy on the cellular immune response in chronic hepatitis B
-
Chen Y, Li X, Ye B, et al,. Effect of telbivudine therapy on the cellular immune response in chronic hepatitis B. Antiviral Res 2011a; 91 (1): 23-31.
-
(2011)
Antiviral Res
, vol.91
, Issue.1
, pp. 23-31
-
-
Chen, Y.1
Li, X.2
Ye, B.3
-
70
-
-
84874614698
-
Baseline peripheral NK and its early dynamic changes predicts 24 weeks treatment efficacy in hepatitis B antigen positive chronic hepatitis patients - A single center experience from 54 patients treated with telbivudine (LDT)
-
Chen T, Ding L, Guo W, et al,. Baseline peripheral NK and its early dynamic changes predicts 24 weeks treatment efficacy in hepatitis B antigen positive chronic hepatitis patients-A single center experience from 54 patients treated with telbivudine (LDT). Hepatology 2010; 52 (2 Suppl.): 564A.
-
(2010)
Hepatology
, vol.52
, Issue.2 SUPPL.
-
-
Chen, T.1
Ding, L.2
Guo, W.3
-
71
-
-
64849116017
-
PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells
-
Parekh VV, Lalani S, Kim S, et al,. PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells. J Immunol 2009; 182 (5): 2816-2826.
-
(2009)
J Immunol
, vol.182
, Issue.5
, pp. 2816-2826
-
-
Parekh, V.V.1
Lalani, S.2
Kim, S.3
-
72
-
-
0037967918
-
Liver NKT cells: An account of heterogeneity
-
DOI 10.1016/S1471-4906(03)00162-5
-
Emoto M, Kaufmann SH,. Liver NKT cells: an account of heterogeneity. Trends Immunol 2003; 24 (7): 364-369. (Pubitemid 36830962)
-
(2003)
Trends in Immunology
, vol.24
, Issue.7
, pp. 364-369
-
-
Emoto, M.1
Kaufmann, S.H.E.2
-
73
-
-
58149189061
-
Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy
-
Chang WS, Kim JY, Kim YJ, et al,. Cutting edge: programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. J Immunol 2008; 181 (10): 6707-6710.
-
(2008)
J Immunol
, vol.181
, Issue.10
, pp. 6707-6710
-
-
Chang, W.S.1
Kim, J.Y.2
Kim, Y.J.3
-
74
-
-
84861483182
-
Effects of antiviral therapy with telbivudine on peripheral iNKT cells in HBeAg(+) chronic hepatitis B patients
-
Shi TD, Zhang JM, Wang XF, Chen M, Sun H, Chen CB, Ren H., Effects of antiviral therapy with telbivudine on peripheral iNKT cells in HBeAg(+) chronic hepatitis B patients. Clin Exp Med 2011; 12 (2): 105-113.
-
(2011)
Clin Exp Med
, vol.12
, Issue.2
, pp. 105-113
-
-
Shi, T.D.1
Zhang, J.M.2
Wang, X.F.3
Chen, M.4
Sun, H.5
Chen, C.B.6
Ren, H.7
-
75
-
-
84874591339
-
Effect of telbivudine on the function of dendritic cells in patients with chronic hepatitis B
-
Pan XC,. Effect of telbivudine on the function of dendritic cells in patients with chronic hepatitis B. Hepatol Int 2012; 6: 44-66.
-
(2012)
Hepatol Int
, vol.6
, pp. 44-66
-
-
Pan, X.C.1
-
76
-
-
84862243752
-
Telbivudine improves the function of myeloid dendritic cells in patients with chronic hepatitis B
-
Pan XC, Yao W, Fu JJ, et al,. Telbivudine improves the function of myeloid dendritic cells in patients with chronic hepatitis B. Acta Virol 2012; 56: 31-38.
-
(2012)
Acta Virol
, vol.56
, pp. 31-38
-
-
Pan, X.C.1
Yao, W.2
Fu, J.J.3
-
77
-
-
84874613867
-
Role of natural killer (NK) cells and toll-like receptor 9 (TLR9) in early responder to telbivudine for chronic hepatitis B patients
-
Gao YQ,. Role of natural killer (NK) cells and toll-like receptor 9 (TLR9) in early responder to telbivudine for chronic hepatitis B patients. Hepatol International 2012; 6: 61.
-
(2012)
Hepatol International
, vol.6
, pp. 61
-
-
Gao, Y.Q.1
-
78
-
-
42649134105
-
Interleukin-21: Basic biology and implications for cancer and autoimmunity
-
DOI 10.1146/annurev.immunol.26.021607.090316
-
Spolski R, Leonard WJ,. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu Rev Immunol 2008; 26: 57-79. (Pubitemid 351600371)
-
(2008)
Annual Review of Immunology
, vol.26
, pp. 57-79
-
-
Spolski, R.1
Leonard, W.J.2
-
79
-
-
67849120058
-
Interleukin-21 as a new therapeutic target for immune-mediated diseases
-
Monteleone G, Pallone F, Macdonald TT,. Interleukin-21 as a new therapeutic target for immune-mediated diseases. Trends Pharmacol Sci 2009; 30: 441-447.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 441-447
-
-
Monteleone, G.1
Pallone, F.2
Macdonald, T.T.3
-
80
-
-
84874637204
-
Alterations in CD4 + CXCR5 + TFH cells in different clinical stages of chronic HBV infection
-
Feng JY, Zhao PW, Jiang YF,. Alterations in CD4 + CXCR5 + TFH cells in different clinical stages of chronic HBV infection. J Hepatology 2011; 54 (Suppl. 1): S120.
-
(2011)
J Hepatology
, vol.54
, Issue.SUPPL. 1
-
-
Feng, J.Y.1
Zhao, P.W.2
Jiang, Y.F.3
|