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Volumn 46, Issue 1, 2007, Pages 45-52

Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma

Author keywords

Chronic hepatitis B; Cirrhosis; HBeAg seroconversion; Hepatocellular carcinoma; Interferon

Indexed keywords

ALPHA INTERFERON; CORTICOSTEROID; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; RECOMBINANT ALPHA2A INTERFERON;

EID: 33751514752     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.08.021     Document Type: Article
Times cited : (287)

References (36)
  • 1
    • 33846959569 scopus 로고    scopus 로고
    • Natural history differences in perinatally versus adult-acquired disease
    • Chu C.M., and Liaw Y.F. Natural history differences in perinatally versus adult-acquired disease. Curr Hepat Rep 3 (2004) 123-131
    • (2004) Curr Hepat Rep , vol.3 , pp. 123-131
    • Chu, C.M.1    Liaw, Y.F.2
  • 2
    • 0027378724 scopus 로고
    • Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis.
    • Wong D.K.H., Cheung A.M., O'Rourke K., Naylor C.D., Detsky A.S., and Heathcote J. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann Intern Med 119 (1993) 312-323
    • (1993) Ann Intern Med , vol.119 , pp. 312-323
    • Wong, D.K.H.1    Cheung, A.M.2    O'Rourke, K.3    Naylor, C.D.4    Detsky, A.S.5    Heathcote, J.6
  • 3
    • 0027944159 scopus 로고
    • Prednisone-interferon combination in the treatment of chronic hepatitis B: direct and indirect meta-analysis
    • Cohard M., Poynard T., Mathurin P., and Zarski J.P. Prednisone-interferon combination in the treatment of chronic hepatitis B: direct and indirect meta-analysis. Hepatology 20 (1994) 1390-1398
    • (1994) Hepatology , vol.20 , pp. 1390-1398
    • Cohard, M.1    Poynard, T.2    Mathurin, P.3    Zarski, J.P.4
  • 4
    • 0029893146 scopus 로고    scopus 로고
    • Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B
    • Niederau C., Heintges T., Lange S., Goldmann G., Niederau C.M., Mohr L., and Haussinger D. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N Engl J Med 334 (1996) 1422-1427
    • (1996) N Engl J Med , vol.334 , pp. 1422-1427
    • Niederau, C.1    Heintges, T.2    Lange, S.3    Goldmann, G.4    Niederau, C.M.5    Mohr, L.6    Haussinger, D.7
  • 5
    • 0032032927 scopus 로고    scopus 로고
    • Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus. A pilot study
    • Ikeda K., Saitoh S., Suzuki Y., Kobayashi M., Tsubota A., Fukuda M., Koida I., et al. Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus. A pilot study. Cancer 82 (1998) 827-835
    • (1998) Cancer , vol.82 , pp. 827-835
    • Ikeda, K.1    Saitoh, S.2    Suzuki, Y.3    Kobayashi, M.4    Tsubota, A.5    Fukuda, M.6    Koida, I.7
  • 6
    • 0033027690 scopus 로고    scopus 로고
    • Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection
    • Lin S.M., Sheen I.S., Chien R.N., Chu C.M., and Liaw Y.F. Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection. Hepatology 29 (1999) 971-975
    • (1999) Hepatology , vol.29 , pp. 971-975
    • Lin, S.M.1    Sheen, I.S.2    Chien, R.N.3    Chu, C.M.4    Liaw, Y.F.5
  • 7
    • 0030730879 scopus 로고    scopus 로고
    • Long-term follow up of patients with chronic hepatitis B treated with interferon alfa
    • Lau D.T.Y., Everhart J., Kleiner D.E., Park Y., Vergalla J., Schmid P., et al. Long-term follow up of patients with chronic hepatitis B treated with interferon alfa. Gastroenterology 113 (1997) 1660-1667
    • (1997) Gastroenterology , vol.113 , pp. 1660-1667
    • Lau, D.T.Y.1    Everhart, J.2    Kleiner, D.E.3    Park, Y.4    Vergalla, J.5    Schmid, P.6
  • 9
    • 3242683269 scopus 로고    scopus 로고
    • Comparison of long-term effects of lymphoblastoid interferon alpha and recombinant interferon alpha-2a therapy in patients with chronic hepatitis B
    • Lin S.M., Tai D.I., Chien R.N., Sheen I.S., Chu C.M., and Liaw Y.F. Comparison of long-term effects of lymphoblastoid interferon alpha and recombinant interferon alpha-2a therapy in patients with chronic hepatitis B. J Viral Hepat 11 (2004) 349-357
    • (2004) J Viral Hepat , vol.11 , pp. 349-357
    • Lin, S.M.1    Tai, D.I.2    Chien, R.N.3    Sheen, I.S.4    Chu, C.M.5    Liaw, Y.F.6
  • 10
    • 0034962643 scopus 로고    scopus 로고
    • Long-term follow-up of interferon alfa treatment in Chinese patients with chronic hepatitis B infection: the effect on hepatitis B e antigen seroconversion and the development of cirrhosis-related complications
    • Yuen M.F., Hui C.K., Cheng C.C., Wu C.H., Lai Y.P., and Lai C.L. Long-term follow-up of interferon alfa treatment in Chinese patients with chronic hepatitis B infection: the effect on hepatitis B e antigen seroconversion and the development of cirrhosis-related complications. Hepatology 34 (2001) 139-145
    • (2001) Hepatology , vol.34 , pp. 139-145
    • Yuen, M.F.1    Hui, C.K.2    Cheng, C.C.3    Wu, C.H.4    Lai, Y.P.5    Lai, C.L.6
  • 12
    • 0036019518 scopus 로고    scopus 로고
    • Hepatitis B viral genotypes: clinical relevance and molecular characteristics
    • Kao J.H. Hepatitis B viral genotypes: clinical relevance and molecular characteristics. J Gastroenterol Hepatol 17 (2002) 643-650
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 643-650
    • Kao, J.H.1
  • 13
    • 0022641584 scopus 로고
    • Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. A prospective study
    • Liaw Y.F., Tai D.Y., Chu C.M., Lin D.Y., Sheen I.S., Chen T.J., and Pao C.C. Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. A prospective study. Gastroenterology 90 (1986) 263-267
    • (1986) Gastroenterology , vol.90 , pp. 263-267
    • Liaw, Y.F.1    Tai, D.Y.2    Chu, C.M.3    Lin, D.Y.4    Sheen, I.S.5    Chen, T.J.6    Pao, C.C.7
  • 14
    • 0029366631 scopus 로고
    • Acute exacerbation and superinfection in patients with chronic viral hepatitis
    • Liaw Y.F. Acute exacerbation and superinfection in patients with chronic viral hepatitis. J Formosan Med Assoc 94 (1995) 521-528
    • (1995) J Formosan Med Assoc , vol.94 , pp. 521-528
    • Liaw, Y.F.1
  • 15
    • 0023147172 scopus 로고
    • Changes of serum hepatitis B virus DNA in two types of clinical events preceding spontaneous hepatitis B e antigen seroconversion in chronic type B hepatitis
    • Liaw Y.F., Pao C.C., Chu C.M., Sheen I.S., and Huang M.J. Changes of serum hepatitis B virus DNA in two types of clinical events preceding spontaneous hepatitis B e antigen seroconversion in chronic type B hepatitis. Hepatology 7 (1987) 1-3
    • (1987) Hepatology , vol.7 , pp. 1-3
    • Liaw, Y.F.1    Pao, C.C.2    Chu, C.M.3    Sheen, I.S.4    Huang, M.J.5
  • 16
    • 0142244873 scopus 로고    scopus 로고
    • Determinants for sustained HBeAg response to lamivudine therapy
    • Chien R.N., Yeh C.T., Tsai S.L., Chu C.M., and Liaw Y.F. Determinants for sustained HBeAg response to lamivudine therapy. Hepatology 38 (2003) 1267-1273
    • (2003) Hepatology , vol.38 , pp. 1267-1273
    • Chien, R.N.1    Yeh, C.T.2    Tsai, S.L.3    Chu, C.M.4    Liaw, Y.F.5
  • 17
    • 0023762809 scopus 로고
    • The development of cirrhosis in patients with chronic type B hepatitis: a prospective study
    • Liaw Y.F., Tai D.I., Chu C.M., and Chen T.J. The development of cirrhosis in patients with chronic type B hepatitis: a prospective study. Hepatology 8 (1988) 493-496
    • (1988) Hepatology , vol.8 , pp. 493-496
    • Liaw, Y.F.1    Tai, D.I.2    Chu, C.M.3    Chen, T.J.4
  • 18
    • 0000336139 scopus 로고
    • Regression model and life tables
    • Cox D.R. Regression model and life tables. J R Stat Soc B 34 (1972) 187-220
    • (1972) J R Stat Soc B , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 19
    • 20444363583 scopus 로고    scopus 로고
    • Asian Pacific consensus statement on the management of chronic hepatitis B: a 2005 update
    • Liaw Y.F., Leung N., Guan G., Lau G.K.K., Merican I., McCaughan G., Gane E., et al. Asian Pacific consensus statement on the management of chronic hepatitis B: a 2005 update. Liver Int 25 (2005) 472-489
    • (2005) Liver Int , vol.25 , pp. 472-489
    • Liaw, Y.F.1    Leung, N.2    Guan, G.3    Lau, G.K.K.4    Merican, I.5    McCaughan, G.6    Gane, E.7
  • 20
    • 0033037480 scopus 로고    scopus 로고
    • Interferon alfa for chronic hepatitis B infection: increased efficacy of prolonged treatment
    • Janssen H.L.A., Gerken G., Carreno V., Marcellin P., Naoumov N.V., Craxi A., et al. Interferon alfa for chronic hepatitis B infection: increased efficacy of prolonged treatment. Hepatology 30 (1999) 238-243
    • (1999) Hepatology , vol.30 , pp. 238-243
    • Janssen, H.L.A.1    Gerken, G.2    Carreno, V.3    Marcellin, P.4    Naoumov, N.V.5    Craxi, A.6
  • 21
    • 0033000312 scopus 로고    scopus 로고
    • Retreatment of chronic hepatitis B e antigen-positive patients with recombinant interferon alfa-2a. The European Concerted Action on Viral Hepatitis (EUROHEP)
    • Carreno V., Marcellin P., Hadziyannis S., Salmeron J., Diago M., Kitis G.E., et al. Retreatment of chronic hepatitis B e antigen-positive patients with recombinant interferon alfa-2a. The European Concerted Action on Viral Hepatitis (EUROHEP). Hepatology 30 (1999) 277-282
    • (1999) Hepatology , vol.30 , pp. 277-282
    • Carreno, V.1    Marcellin, P.2    Hadziyannis, S.3    Salmeron, J.4    Diago, M.5    Kitis, G.E.6
  • 22
    • 0038045171 scopus 로고    scopus 로고
    • Peginterferon α-2a (40KD): an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Cooksley W.G.E., Piratvisuth T., Lee S.D., Mahachai V., Chao Y.C., Tanwandee T., et al. Peginterferon α-2a (40KD): an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B. J Viral Hepat 10 (2003) 298-305
    • (2003) J Viral Hepat , vol.10 , pp. 298-305
    • Cooksley, W.G.E.1    Piratvisuth, T.2    Lee, S.D.3    Mahachai, V.4    Chao, Y.C.5    Tanwandee, T.6
  • 23
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau G.K.K., Piratvisuth T., Luo K.X., Marcellin P., Thongsawat S., Coosley G., et al. Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. New Engl J Med 352 (2005) 2682-2695
    • (2005) New Engl J Med , vol.352 , pp. 2682-2695
    • Lau, G.K.K.1    Piratvisuth, T.2    Luo, K.X.3    Marcellin, P.4    Thongsawat, S.5    Coosley, G.6
  • 24
    • 0033520109 scopus 로고    scopus 로고
    • Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. HIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy
    • Yoshida H., Shiratori Y., Moriyama M., Arakawa Y., Ide T., Sata M., et al. Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. HIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy. Ann Intern Med 131 (1999) 174-181
    • (1999) Ann Intern Med , vol.131 , pp. 174-181
    • Yoshida, H.1    Shiratori, Y.2    Moriyama, M.3    Arakawa, Y.4    Ide, T.5    Sata, M.6
  • 25
    • 19944428400 scopus 로고    scopus 로고
    • Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival
    • Shiratori Y., Ito Y., Yokosuka O., Imazeki F., Nakata R., Tanaka N., et al. Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival. Ann Intern Med 142 (2005) 105-114
    • (2005) Ann Intern Med , vol.142 , pp. 105-114
    • Shiratori, Y.1    Ito, Y.2    Yokosuka, O.3    Imazeki, F.4    Nakata, R.5    Tanaka, N.6
  • 26
    • 0035110693 scopus 로고    scopus 로고
    • The long-term outcome of interferon-alpha treated and untreated patients with HBeAg-negative chronic hepatitis B
    • Papatheodoridis G.V., Manesis E., and Hadziyannis S.J. The long-term outcome of interferon-alpha treated and untreated patients with HBeAg-negative chronic hepatitis B. J Hepatol 34 (2001) 306-313
    • (2001) J Hepatol , vol.34 , pp. 306-313
    • Papatheodoridis, G.V.1    Manesis, E.2    Hadziyannis, S.J.3
  • 27
    • 0037381649 scopus 로고    scopus 로고
    • Long-term suppression of hepatitis B e antigen-negative chronic hepatitis B by 24-month interferon therapy
    • Lampertico P., Del Ninno E., Vigano M., Romeo R., Donato M.F., Sablon E., et al. Long-term suppression of hepatitis B e antigen-negative chronic hepatitis B by 24-month interferon therapy. Hepatology 37 (2003) 756-763
    • (2003) Hepatology , vol.37 , pp. 756-763
    • Lampertico, P.1    Del Ninno, E.2    Vigano, M.3    Romeo, R.4    Donato, M.F.5    Sablon, E.6
  • 28
    • 84984555343 scopus 로고    scopus 로고
    • Hepatitis B e antigen and the risk of hepatocellular carcinoma
    • Yang H.I., Lu S.N., Liaw Y.F., You S.L., Sun C.A., Wang L.Y., et al. Hepatitis B e antigen and the risk of hepatocellular carcinoma. N Eng J Med 347 (2002) 168-174
    • (2002) N Eng J Med , vol.347 , pp. 168-174
    • Yang, H.I.1    Lu, S.N.2    Liaw, Y.F.3    You, S.L.4    Sun, C.A.5    Wang, L.Y.6
  • 29
    • 84983726628 scopus 로고    scopus 로고
    • Hepatitis B genotypes and the response to interferon therapy
    • Kao J.H., Wu N.H., Chen P.J., Lai M.Y., and Chen D.S. Hepatitis B genotypes and the response to interferon therapy. J Hepatol 33 (2000) 998-1002
    • (2000) J Hepatol , vol.33 , pp. 998-1002
    • Kao, J.H.1    Wu, N.H.2    Chen, P.J.3    Lai, M.Y.4    Chen, D.S.5
  • 30
    • 0036896130 scopus 로고    scopus 로고
    • HBV genotype B is associated with better response to interferon therapy in HBeAg(+) chronic hepatitis than genotype C
    • Wai C.T., Chu C.J., Hussain M., and Lok A.S. HBV genotype B is associated with better response to interferon therapy in HBeAg(+) chronic hepatitis than genotype C. Hepatology 36 (2002) 1425-1430
    • (2002) Hepatology , vol.36 , pp. 1425-1430
    • Wai, C.T.1    Chu, C.J.2    Hussain, M.3    Lok, A.S.4
  • 31
    • 84984535720 scopus 로고    scopus 로고
    • Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
    • Kao J.H., Chen P.J., Lai M.Y., and Chen D.S. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 118 (2000) 554-559
    • (2000) Gastroenterology , vol.118 , pp. 554-559
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 32
    • 4644219526 scopus 로고    scopus 로고
    • Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma
    • Chan H.L., Hui A.Y., Wong M.L., Tse A.M.L., Hung L.C.T., Wong V.W.S., et al. Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma. Gut 53 (2004) 1494-1498
    • (2004) Gut , vol.53 , pp. 1494-1498
    • Chan, H.L.1    Hui, A.Y.2    Wong, M.L.3    Tse, A.M.L.4    Hung, L.C.T.5    Wong, V.W.S.6
  • 33
    • 13844322073 scopus 로고    scopus 로고
    • Hepatitis B virus genotype and DNA level and hepatocellular carcinoma: a prospective study in men
    • Yu M.W., Yeh S.H., Chen P.J., Liaw Y.F., Lin C.L., Liu C.J., et al. Hepatitis B virus genotype and DNA level and hepatocellular carcinoma: a prospective study in men. J Natl Cancer Inst 97 (2005) 265-272
    • (2005) J Natl Cancer Inst , vol.97 , pp. 265-272
    • Yu, M.W.1    Yeh, S.H.2    Chen, P.J.3    Liaw, Y.F.4    Lin, C.L.5    Liu, C.J.6
  • 34
    • 19544391413 scopus 로고    scopus 로고
    • Lamivudine for patients with chronic hepatitis B and advanced liver disease
    • Liaw Y.F., Sung J.J.Y., Chow W.C., Farrell G., Lee C.Z., Yuen H., et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 351 (2004) 1521-1531
    • (2004) N Engl J Med , vol.351 , pp. 1521-1531
    • Liaw, Y.F.1    Sung, J.J.Y.2    Chow, W.C.3    Farrell, G.4    Lee, C.Z.5    Yuen, H.6
  • 35
    • 0037383496 scopus 로고    scopus 로고
    • EASL Jury. EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002: Geneva, Switzerland. Consensus statement (short version). J Hepatol. 2003;38:533-540.
  • 36
    • 18644369134 scopus 로고    scopus 로고
    • Treatment alternatives for chronic hepatitis B virus infection: a cost-effective analysis
    • Kanwal F., Gralnek I.M., Martin P., Dulai G.S., Farid M., and Spiegel B.M.R. Treatment alternatives for chronic hepatitis B virus infection: a cost-effective analysis. Ann Intern Med 142 (2005) 821-831
    • (2005) Ann Intern Med , vol.142 , pp. 821-831
    • Kanwal, F.1    Gralnek, I.M.2    Martin, P.3    Dulai, G.S.4    Farid, M.5    Spiegel, B.M.R.6


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