Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 9, 2006, Pages 3147-3152

  Khare, Sagar D ^a,b   Dokholyan, Nikolay V ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

plug; A4V; G37R; H46R; Protein dynamics

Indexed keywords

ALANINE; ARGININE; COPPER ZINC SUPEROXIDE DISMUTASE; GLYCINE; HISTIDINE; MUTANT PROTEIN; VALINE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BETA SHEET; BINDING SITE; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN STABILITY;

AMYOTROPHIC LATERAL SCLEROSIS; DIMERIZATION; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; SUPEROXIDE DISMUTASE;

EID: 33644748183     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511266103     Document Type: Article

References (39)

1. Valentine, J. S., Doucette, P. A. & Potter, S. Z. (2005) Annu. Rev. Biochem. 74, 563-593.
2. Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., Oregan, J. P., Deng, H. X., et al. (1993) Nature 362, 59-62.
3. Gurney, M. E., Pu, H. F., Chiu, A. Y., Dalcanto, M. C., Polchow, C. Y., Alexander, D. D., Caliendo, J., Hentati, A., Kwon, Y. W., Deng, H. X., et al. (1994) Science 264, 1772-1775.
4. Gaudette, M., Hirano, M. & Siddique, T. (2000) Amyotrophic Lateral Scler. Other Motor Neuron Disorders 1, 83-89.
5. Cleveland, D. W. & Rothstein, J. D. (2001) Nat. Rev. Neurosci. 2, 806-819.
6. Okado-Matsumoto, A. & Fridovich, I. (2002) Proc. Natl. Acad. Sci. USA 99, 9010-9014.
7. Bruening, W., Roy, J., Giasson, B., Figlewicz, D. A., Mushynski, W. E. & Durham, H. D. (1999) J. Neurochem. 72, 693-699.
8. Khare, S. D., Caplow, M. & Dokholyan, N. V. (2004) Proc. Natl. Acad. Sci. USA 101, 15094-15099.
9. Ray, S. S., Nowak, R. J., Strokovich, K., Brown, R. H., Walz, T. & Lansbury, P. T. (2004) Biochemistry 43, 4899-4905.
10. Rakhit, R., Crow, J. P., Lepock, J. R., Kondejewski, L. H., Cashman, N. R. & Chakrabartty, A. (2004) J. Biol. Chem. 279, 15499-15504.
11. Ray, S. S., Nowak, R. J., Brown, R. H. & Lansbury, P. T. (2005) Proc. Natl. Acad. Sci. USA 102, 3639-3644.
12. Lindberg, M. J., Tibell, L. & Oliveberg, M. (2002) Proc. Natl. Acad. Sci. USA 99, 16607-16612.
13. Lindberg, M. J., Bystrom, R., Boknas, N., Andersen, P. M. & Oliveberg, M. (2005) Proc. Natl. Acad. Sci. USA 102, 9754-9759.
14. Rodriguez, J. A., Shaw, B. F., Durazo, A., Sohn, S. H., Doucette, P. A., Nersissian, A. M., Faull, K. F., Eggers, D. K., Tiwari, A., Hayward, L. J., et al. (2005) Proc. Natl. Acad. Sci. USA 102, 10516-10521.
15. Tiwari, A. & Hayward, L. J. (2003) J. Biol. Chem. 278, 5984-5992.
16. Tiwari, A., Xu, Z. S. & Hayward, L. J. (2005) J. Biol. Chem. 280, 29771-29779.
17. Shipp, E. L., Cantini, F., Bertini, I., Valentine, J. S. & Banci, L. (2003) Biochemistry 42, 1890-1899.
18. Lockless, S. W. & Ranganathan, R. (1999) Science 286, 295-299.
19. Suel, G. M., Lockless, S. W., Wall, M. A. & Ranganathan, R. (2003) Nat. Struct. Biol. 10, 59-69.
20. Fuentes, E. J., Der, C. J. & Lee, A. L. (2004) J. Mol. Biol. 335, 1105-1115.
21. Gunasekaran, K., Nussinov, R. & Ma, B. (2004) Proteins Struct. Funct. Bioinformat. 57, 433-443.
22. Hart, P. J., Liu, H. B., Pellegrini, M., Nersissian, A. M., Gralla, E. B., Valentine, J. S. & Eisenberg, D. (1998) Protein Sci. 7, 545-555.
23. Chillemi, G., Falconi, M., Amadei, A., Zimatore, G., Desideri, A. & DiNola, A. (1997) Biophys. J. 73, 1007-1018.
24. Luo, J. & Bruice, T. C. (2004) Proc. Natl. Acad. Sci. USA 101, 13152-13156.
25. Amadei, A., Linssen, A. B. M. & Berendsen, H. J. C. (1993) Proteins Struct. Fund. Bioinformat. 17, 412-425.
26. Silva, N. D., Gratton, E., Mei, G., Rosato, N. & FinazziAgro, A. (1992) FASEB J. 6, A311.
27. Ferraroni, M., Rypniewski, W., Wilson, K. S., Viezzoli, M. S., Banci, L., Bertini, I. & Mangani, S. (1999) J. Mol. Biol. 288, 413-426.
28. Banci, L., Bertini, L., Cramaro, F., Del Conte, R., Rosato, A. & Viezzoli, M. S. (2000) Biochemistry 39, 9108-9118.
29. Strange, R. W., Antonyuk, S., Hough, M. A., Doucette, P. A., Rodriguez, J. A., Hart, P. J., Hayward, L. J., Valentine, J. S. & Hasnain, S. S. (2003) J. Mol. Biol. 328, 877-891.
30. Elam, J. S., Taylor, A. B., Strange, R., Antonyuk, S., Doucette, P. A., Rodriguez, J. A., Hasnain, S. S., Hayward, L. J., Valentine, J. S., Yeates, T. O., et al. (2003) Nat. Struct. Biol. 10, 461-467.
31. Richardson, J. S. & Richardson, D. C. (2002) Proc. Natl. Acad. Sci. USA 99, 2754-2759.
32. Khare, S. D., Ding, F. & Dokholyan, N. V. (2003) J. Mol. Biol. 334, 515-525.
33. Khare, S. D., Wilcox, K. C., Gong, P. & Dokholyan, N. V. (2005) Proteins Struct. Fund. Bioinformat. 61, 617-632.
34. Sambashivan, S., Liu, Y. S., Sawaya, M. R., Gingery, M. & Eisenberg, D. (2005) Nature 437, 266-269.
35. Ding, F., Prutzman, K. C., Campbell, S. L. & Dokholyan, N. V. (2006) Structure 14, 5-14.
36. Pearlman, D. A., Case, D. A., Caldwell, J. W., Ross, W. S., Cheatham, T. E., Debolt, S. E., Ferguson, D. M., Seibel, G. L. & Kollman, P. A. (1995) Comput. Phys. Commun. 91, 1-41.
37. Mirny, L. & Domany, E. (1996) Proteins Struct. Fund. Genet. 26, 391-410.
38. Dokholyan, N. V., Li, L., Ding, F. & Shakhnovich, E. I. (2002) Proc. Natl. Acad. Sci. USA 99, 8637-8641.
39. Dokholyan, N. V. (2005) Gene 347, 199-206.