An increase of lycopene content in tomato fruit is associated with a novel Cyc-B allele isolated through TILLING technology

Molecular Breeding

Volumn 31, Issue 3, 2013, Pages 665-674

  Silletti, Maria Francesca ^a   Petrozza, Angelo ^a   Stigliani, Adriana Lucia ^a   Giorio, Giovanni ^a   Cellini, Francesco ^a   D'Ambrosio, Caterina ^a   Carriero, Filomena ^a  

^a Metapontum Agrobios   (Italy)

Author keywords

Carotenoid; Field trial; Lycopene; Mutation; TILLING; Tomato

Indexed keywords

AGRONOMY; FRUIT JUICES; FRUITS; GENES;

CYCLASES; FIELD TRIAL; GENES ENCODE; LYCOPENE CONTENT; LYCOPENES; MUTATION; PHENOTYPIC ANALYSIS; TILLING; TOMATO; TOMATO FRUITS;

CAROTENOIDS;

LYCOPERSICON ESCULENTUM;

EID: 84874560695     PISSN: 13803743     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11032-012-9824-6     Document Type: Article

References (33)

1. Bartley GE, Scolnik PA (1995) Plant carotenoid: pigments for photoprotection, visual attraction, and human health. Plant Cell 7: 1027-1038.
2. Bassi R, Pineau B, Dainese P, Marquardt J (1993) Carotenoid-binding proteins of photosystem II. Eur J Biochem 212: 297-303.
3. Bouvier F, d'Harlingue A, Backhaus RA, Kumagai MH, Camara B (2000) Identification of neoxanthin synthase as a carotenoid cyclase paralog. Eur J Biochem 267: 6346-6352.
4. Britton G (1995) Structure and properties of carotenoids in relation to function. FASEB J 9: 1551-1558.
5. Caldwell DG, McCallum N, Shaw P, Muehlbauer GJ, Marshall DF, Waugh R (2004) A structured mutant population for forward and reverse genetics in Barley (Hordeum vulgare L.). Plant J 40(1): 143-150.
6. Dahmani-Mardas F, Troadec C, Boualem A, Lévêque S, Alsadon AA et al (2010) Engineering melon plants with improved fruit shelf life using the TILLING approach. PLoS One 5(12): e15776.
7. Dalal M, Chinnusamy V, Bansal KC (2010) Isolationl and functional characterization of lycopene β-cyclase (CYC-B) promoter from Solanum habrochaites. BMC Plant Biol 10: 61.
8. Dalmais M, Schmidt J, Le Signor C, Moussy F, Burstin J, Savois V, Aubert G, Brunaud V, de Oliveira Y, Guichard C et al (2008) UTILLdb, a Pisum sativum in silico forward and reverse genetics tool. Genome Biol 9(2): R43.
9. D'Ambrosio C, Stigliani AL, Giorio G (2011) Overexpression of CrtR-b2 (carotene beta hydroxylase 2) from S. lycopersicum L. differentially affects xanthophyll synthesis and accumulation in transgenic tomato plants. Transgenic Res 20(1): 47-60.
10. Eisenreich W, Rohdich F, Bacher A (2001) Deoxyxylulose phosphate pathway to terpenoids. Trends Plant Sci 6: 78-84.
11. Gady ALF, Vriezen WH, van de Wal MHBJ, Huang P, Bovy AG, Visser RGF, Bachem CWB (2012) Induced point mutations in the phytoene synthase 1 gene cause differences in carotenoid content during tomato fruit ripening. Mol Breed 29: 801-812. doi: 10. 1007/s11032-011-9591-9.
12. Hadley CW, Miller EC, Schwartz SJ, Clinton SK (2002) Tomatoes, lycopene, and prostate cancer: progress and promise. Exp Biol Med 227: 869-880.
13. Hirschberg J (2001) Carotenoid biosynthesis in flowering plants. Curr Opin Plant Biol 4: 210-218.
14. Hunter WN (2007) The non-mevalonate pathway of isoprenoid precursor biosynthesis. J Biol Chem 282: 21573-21577.
15. Krinsky NI, Johnson EJ (2005) Carotenoid actions and their relation to health and disease. Mol Aspects Med 26: 459-516.
16. Lakshman MR, Okoh C (1993) Enzymatic conversion of all trans-beta-carotene to retinal. Meth Enzymol 214: 256-269.
17. Lindgren L, Stahlberg KG, Hoglund AS (2003) Seed-specific overexpression of an endogenous Arabidopsis phytoene synthase gene results in delayed germination and increased levels of carotenoids, chlorophyll, and abscisic acid. Plant Physiol 132: 779-785.
18. McCallum CM, Comai L, Greene EA, Henikoff S (2000) Targeting induced local lesions in genomes (TILLING) for plant functional genomics. Plant Physiol 123(2): 439-442.
19. Minoia S, Petrozza A, D'Onofrio O, Piron F, Mosca G, Sozio G, Cellini F, Bendahmane A, Carriero F (2010) A new mutant genetic resource for tomato crop improvement by TILLING technology. BMC Res Notes 3: 69.
20. Mordente A, Guantario B, Meucci E, Silvestrini A, Lombardi E, Martorana GE, Giardina B, Böhm V (2011) Lycopene and cardiovascular diseases: an update. Curr Med Chem 18(8): 1146-1163.
21. Ng P, Henikoff S (2003) SIFT: predicting amino acid changes that affect protein function. Nucleic Acids Res 31: 3812-3814.
22. Okabe Y, Asamizu E, Saito T, Matsukura C, Ariizumi T, Brès C, Rothan C, Mizoguchi T, Ezura H (2011) Tomato TILLING technology: development of a reverse genetics tool for the efficient isolation of mutants from Micro-Tom mutant libraries. Plant Cell Physiol 52(11): 1994-2005.
23. Pecker I, Gabbay R, Cunningham FX Jr, Hirschberg J (1996) Cloning and characterization of the cDNA for lycopene beta-cyclase from tomato reveals decrease in its expression during fruit ripening. Plant Mol Biol 30(4): 807-819.
24. Piron F, Nicolai M, Minoia S, Piednoir E, Moretti A et al (2010) An induced mutation in tomato eIF4E leads to immunity to two potyviruses. PLoS One 5(6): e11313.
25. Rock CD, Zeevaart JAD (1991) The aba mutant of Arabidopsis thaliana is impaired in epoxy-carotenoid biosynthesis. Proc Natl Acad Sci USA 88: 7496-7499.
26. Ronen G, Carmel-Goren L, Zamir D, Hirschberg J (2000) Analternative pathway to beta-carotene formation in plant chromoplasts discovered by map-based cloning of beta and old-gold color mutations in tomato. Proc Natl Acad Sci USA 97: 11102-11107.
27. Rozen S, Skaletsky HJ (2000) Primer3 on the WWW for general users and for biologist programmers. In: Krawetz S, Misener S (eds) Bioinformatics methods and protocols: methods in molecular biology. Humana Press, Totowa, pp 365-386.
28. Slade AJ, Fuerstenberg SI, Loeffler D, Steine MN, Facciotti D (2005) A reverse genetic, nontransgenic approach to wheat crop improvement by TILLING. Nat Biotechnol 23: 75-81.
29. Stigliani AL, Giorio G, D'Ambrosio C (2011) Characterization of P450 carotenoid β- and ε-hydroxylases of tomato and transcriptional regulation of xanthophyll biosynthesis in root, leaf, petal and fruit. Plant Cell Physiol 52: 851-865.
30. Till BJ, Reynolds SH, Weil C, Springer N, Burtner C, Young K, Bowers E, Codomo CA, Enns LC, Odden AR, Greene EA, Comai L, Henikoff S (2004) Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol 4: 12.
31. Till BJ, Cooper J, Tai TH, Colowit P, Greene EA, Henikoff S, Comai L (2007) Discovery of chemically induced mutations in rice by TILLING. BMC Plant Biol 7: 19.
32. Triques K, Sturbois B, Gallais S, Dalmais M, Chauvin S, Clepet C, Aubourg S, Rameau C, Caboche M, Bendahmane A (2007) Characterization of Arabidopsis thaliana mismatch specific endonucleases: application to mutation discovery by TILLING in pea. Plant J 51(6): 1116-1125.
33. Ye X, Al-Babili S, Kloti A, Zhang J, Lucca P, Beyer P, Potrykus I (2000) Engineering the provitamin A (β-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science 287: 303-305.