Sevoflurane Induces Endoplasmic Reticulum Stress Mediated Apoptosis in Hippocampal Neurons of Aging Rats

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Chen, Gang ^a   Gong, Ming ^a   Yan, Min ^a   Zhang, Xiaoming ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 12; CEBP HOMOLOGOUS PROTEIN; CELL PROTEIN; SEVOFLURANE; UNCLASSIFIED DRUG;

ADVERSE OUTCOME; AGING; ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTERIAL GAS; ARTICLE; CELL ASSAY; CELL COUNT; CHROMATIN; COGNITIVE DEFECT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MEMORY DISORDER; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROANATOMY; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPATIAL MEMORY; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; VITAL SIGN;

AGING; ANESTHETICS, INHALATION; ANIMALS; APOPTOSIS; BLOOD GAS ANALYSIS; CASPASE 12; ENDOPLASMIC RETICULUM STRESS; HIPPOCAMPUS; MALE; MEMORY; METHYL ETHERS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SPATIAL BEHAVIOR; TIME FACTORS; TRANSCRIPTION FACTOR CHOP; UP-REGULATION; VITAL SIGNS;

EID: 84874558834     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057870     Document Type: Article

References (37)

1. Monk TG, Weldon BC, Garvan CW, Dede DE, van der Aa MT, et al. (2008) Predictors of cognitive dysfunction after major noncardiac surgery. Anesthesiology 108: 18-30.
2. Culley DJ, Baxter M, Yukhananov R, Crosby G (2003) The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg 96: 1004-1009, table of contents.
3. Liu XS, Xue QS, Zeng QW, Li Q, Liu J, et al. (2010) Sevoflurane impairs memory consolidation in rats, possibly through inhibiting phosphorylation of glycogen synthase kinase-3beta in the hippocampus. Neurobiol Learn Mem 94: 461-467.
4. Culley DJ, Xie Z, Crosby G, (2007) General anesthetic-induced neurotoxicity: an emerging problem for the young and old? Curr Opin Anaesthesiol 20: 408-413.
5. Hudson AE, Hemmings HC Jr, (2011) Are anaesthetics toxic to the brain? Br J Anaesth 107: 30-37.
6. Perouansky M (2008) General anesthetics and long-term neurotoxicity. Handb Exp Pharmacol: 143-157.
7. Eckenhoff RG, Johansson JS, Wei H, Carnini A, Kang B, et al. (2004) Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. Anesthesiology 101: 703-709.
8. Salminen A, Kauppinen A, Suuronen T, Kaarniranta K, Ojala J, (2009) ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J Neuroinflammation 6: 41.
9. Matus S, Glimcher LH, Hetz C, (2011) Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Curr Opin Cell Biol 23: 239-252.
10. Lindholm D, Wootz H, Korhonen L, (2006) ER stress and neurodegenerative diseases. Cell Death Differ 13: 385-392.
11. Boyce M, Yuan J, (2006) Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13: 363-373.
12. Fradejas N, Pastor MD, Burgos M, Beyaert R, Tranque P, et al. (2010) Caspase-11 mediates ischemia-induced astrocyte death: involvement of endoplasmic reticulum stress and C/EBP homologous protein. J Neurosci Res 88: 1094-1105.
13. DeGracia DJ, Montie HL, (2004) Cerebral ischemia and the unfolded protein response. J Neurochem 91: 1-8.
14. Soo KY, Atkin JD, Farg M, Walker AK, Horne MK, et al. (2012) Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis. PLoS One 7: e35413.
15. Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, et al. (2008) The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol 64: 618-627.
16. Dong Y, Zhang G, Zhang B, Moir RD, Xia W, et al. (2009) The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol 66: 620-631.
17. Bittner EA, Yue Y, Xie Z, (2011) Brief review: anesthetic neurotoxicity in the elderly, cognitive dysfunction and Alzheimer's disease. Can J Anaesth 58: 216-223.
18. Alkire MT, Gruver R, Miller J, McReynolds JR, Hahn EL, et al. (2008) Neuroimaging analysis of an anesthetic gas that blocks human emotional memory. Proc Natl Acad Sci U S A 105: 1722-1727.
19. Wiklund A, Granon S, Faure P, Sundman E, Changeux JP, et al. (2009) Object memory in young and aged mice after sevoflurane anaesthesia. Neuroreport 20: 1419-1423.
20. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
21. Landoni G, Rodseth RN, Santini F, Ponschab M, Ruggeri L, et al. (2012) Randomized evidence for reduction of perioperative mortality. J Cardiothorac Vasc Anesth 26: 764-772.
22. Bignami E, Biondi-Zoccai G, Landoni G, Fochi O, Testa V, et al. (2009) Volatile anesthetics reduce mortality in cardiac surgery. J Cardiothorac Vasc Anesth 23: 594-599.
23. Satomoto M, Satoh Y, Terui K, Miyao H, Takishima K, et al. (2009) Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice. Anesthesiology 110: 628-637.
24. Xie Z, Dong Y, Maeda U, Moir R, Inouye SK, et al. (2006) Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci 61: 1300-1306.
25. Li Y, Liang G, Wang S, Meng Q, Wang Q, et al. (2007) Effects of fetal exposure to isoflurane on postnatal memory and learning in rats. Neuropharmacology 53: 942-950.
26. Gupta S, (2001) Molecular steps of death receptor and mitochondrial pathways of apoptosis. Life Sci 69: 2957-2964.
27. Zhang Y, Dong Y, Wu X, Lu Y, Xu Z, et al. (2010) The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem 285: 4025-4037.
28. Ogawa S, Kitao Y, Hori O, (2007) Ischemia-induced neuronal cell death and stress response. Antioxid Redox Signal 9: 573-587.
29. Tabas I, Ron D, (2011) Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol 13: 184-190.
30. Nakagawa T, Zhu H, Morishima N, Li E, Xu J, et al. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103.
31. Oyadomari S, Mori M, (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11: 381-389.
32. Szegezdi E, Fitzgerald U, Samali A, (2003) Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann N Y Acad Sci 1010: 186-194.
33. Rao RV, Ellerby HM, Bredesen DE, (2004) Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 11: 372-380.
34. Zhang K, Kaufman RJ, (2006) The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 66: S102-109.
35. Wei H, Xie Z, (2009) Anesthesia, calcium homeostasis and Alzheimer's disease. Curr Alzheimer Res 6: 30-35.
36. Bezerra FJ, do Vale NB, Macedo Bde O, Rezende AA, Almeida MG (2010) Evaluation of antioxidant parameters in rats treated with sevoflurane. Rev Bras Anestesiol 60: 162-169, 193-167.
37. Wong CH, Liu TZ, Chye SM, Lu FJ, Liu YC, et al. (2006) Sevoflurane-induced oxidative stress and cellular injury in human peripheral polymorphonuclear neutrophils. Food Chem Toxicol 44: 1399-1407.