Different outcomes of unliganded and liganded estrogen receptor-α on neurite outgrowth in PC12 cells

Endocrinology

Volumn 150, Issue 1, 2009, Pages 200-211

  Merot, Yohann ^a   Ferriére, François ^a   Gailhouste, Luc ^a   Huet, Guillaume ^a   Percevault, Frédéric ^a   Saligaut, Christian ^a   Flouriot, Gilles ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DNA BINDING; DNA TRANSCRIPTION; ENZYME REPRESSION; ESTROGEN RESPONSIVE ELEMENT; GENETIC TRANSCRIPTION; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RECEPTOR BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSACTIVATION;

EID: 58149474519     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0449     Document Type: Article

References (51)

1. Nilsson S, Makek S, Treuter E, Tujague M, Thomsen J, Andersson G, Enmark E, Pettersson K, Warner M, Gustafsson JA 2001 Mechanisms of estrogen action. Physiol Rev 81:1535-1565
2. McEwen BS, Alves SE 1999 Estrogen actions in the central nervous system. Endocr Rev 20:279-307
3. Toran-Allerand CD, Singh M, Setalo Jr G 1999 Novel mechanisms of estrogen action in the brain: new players in an old story. Front Neuroendocrinol 20: 97-121
4. Garcia-Segura LM, Azcoitia I, DonCarlos LL 2001 Neuroprotection by estradiol. Prog Neurobiol 63:29-60
5. Maggi A, Ciana P, Belcredito S, Vegeto E 2004 Estrogens in the nervous system: mechanisms and nonreproductive functions. Annu Rev Physiol 66:291-313
6. Nuclear Receptors Nomenclature Committee 1999 A unified nomenclature system for the nuclear receptor superfamily. Cell 97:161-163
7. Dubai DB, Zhu H, Yu J, Rau SW, Shughrue PJ, Merchenthaler I, Kindy MS, Wise PM 2001 Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury. Proc Natl Acad Sci USA 98:1952-1957
8. Antal MC, Krust A, Chambon P, Mark M 2008 Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERβ-null mutant. Proc Natl Acad Sci USA 105:2433-2438
9. Beato M 1989 Gene regulation by steroid hormones. Cell 56:335-344
10. Tora L, White J, Brou C, Tasset D, Webster N, Scheer E, Chambon P 1989 The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 59:477-487
11. McKenna NJ, O'Malley BW 2002 Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108:465-474
12. Edwards DP 2005 Regulation of signal transduction pathways by estrogen and progesterone. Annu Rev Physiol 67:335-376
13. Levin ER 2005 Integration of the extranuclear and nuclear actions of estrogen. Mol Endocrinol 19:1951-1959
14. Wade CB, Dorsa DM 2003 Estrogen activation of cyclic adenosine 5'-monophosphate response element-mediated transcription requires the extracellularly regulated kinase/mitogen-activated protein kinase pathway. Endocrinology 144:832-838
15. Greene LA, Tischler AS 1976 Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 73:2424-2428
16. Cowley S, Paterson H, Kemp P, Marshall CJ 1994 Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of N1H 3T3 cells. Cell 77:841-852
17. Segal RA, Greenberg ME 1996 Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 19:463-489
18. Flouriot G, Brand H, Denger S, Metivier R, Kos M, Reid G, Sonntag-Buck V, Gannon F 2000 Identification of a new7 isoform of the human estrogen receptor-α (hERα) that is encoded by distinct transcripts and that is able to repress hER-α activation function 1. EMBO J 19:4688-4700
19. Metivier R, Stark A, Flouriot G, Hubner MR, Brand H, Penot G, Manu D, Denger S, Reid G, Kos M, Russell RB, Kah O, Pakdel F, Gannon F 2002 A dynamic structural model for estrogen receptor-α activation by ligands, emphasizing the role of interactions between distant A and E domains. Mol Cell 10:1019-1032
20. Busca R, Abbe P, Mantoux F, Aberdam E, Peyssonnaux C, Eychene A, Ortonne JP, Ballotti R 2000 Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes. EMBO J 19:2900-2910
21. Merot Y, Ferriere F, Debroas E, Flouriot G, Duval D, Saligaut C 2005 Estrogen receptor α mediates neuronal differentiation and neuroprotection in PC12 cells: critical role of the A/B domain of the receptor. J Mol Endocrinol 35: 257-267
22. Hawley R], Scheibe RJ, Wagner JA 1992 NGF induces the expression of the VGF gene through a cAMP response element. J Neurosci 12:2573-2581
23. Zentrich E, Han SY, Pessoa-Brandao L, Butterfield L, Heasley LE 2002 Collaboration of JNKs and ERKs in nerve growth factor regulation of the neurofilament light chain promoter in PC12 cells. J Biol Chem 277:4110-4118
24. Jackson TR, Blader IJ, Hammonds-Odie LP, Burga CR, Cooke F, Hawkins FT, Wolf AG, Heldman KA, Theibert AB 1996 Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase. J Cell Sci 109(Pt 2):289-300
25. Marshall CJ 1995 Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185
26. Ginty DD, Bonni A, Greenberg ME 1994 Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-f os transcription via phosphorylation of CREB. Cell 77:713-725
27. Ahn S, Olive M, Aggarwal S, Krylov D, Ginty DD, Vinson C 1998 A dominantnegative inhibitor of CREB reveals that it is a general mediator of stimulusdependent transcription of c-fos. Mol Cell Biol 18:967-977
28. Murphy LO, Smith S, Chen RH, Fingar DC, Blenis J 2002 Molecular interpretation of ERK signal duration by immediate early gene products. Nat Cell Biol 4:556-564
29. Dominguez R, Jalali C, de Lacalle S 2004 Morphological effects of estrogen on cholinergic neurons in vitro involves activation of extracellular signal-regulated kinases. J Neurosci 24:982-990
30. Carrer HF, Cambiasso MJ, Gorosito S 2005 Effects of estrogen on neuronal growth and differentiation. J Steroid Biochem Mol Biol 93:319-323
31. Singh M, Setalo Jr G, Guan X, Frail DE, Toran-Allerand CD 2000 Estrogeninduced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-α knock-out mice. J Neurosci 20:1694-1700
32. McClelland RA, Barrow D, Madden TA, Dutkowski CM, Pamment J, Knowlden JM, Gee JM Nicholson RI 2001 Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen 1CI 182,780 (Faslodex). Endocrinology 142:2776-2788
33. Acconcia F, Ascenzi P, Bocedi A, Spisni E, Tomasi V, Trentalance A, Visca P, Marino M 2005 Palmitoylation-dependent estrogen receptor α membrane localization: regulation by 17β-estradiol. Mol Biol Cell 16:231-237
34. Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW Liao JK 2000 Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407:538-541
35. Castoria G, Migliaccio A, Bilancio A, Di Domenico M, de Falco A, Lombardi M, Florentino R, Varricchio L, Barone MV, Auricchio F 2001 PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J 20:6050-6059
36. αi. J Biol Chem 276:27071-27076
37. Gallo D, Haddad I, Duvillier H, Jacquemotte F, Laïos I, Laurent G, Jacquot Y, Vinh J, Leclercq G 2008 Trophic effect in MCF-7 cells of ERα17p, a peptide corresponding to a platform regulatory motif of the estrogen receptor α: underlying mechanisms. J Steroid Biochem Mol Biol 109:138-149
38. Gallo D, Haddad I, Laurent G, Vinh J, Jacquemotte F, Jacquot Y, Leclercq G 2008 Regulatory function of the P295-T311 motif of the estrogen receptor α: does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses? Nucl Recept Signal 6:e007
39. Filardo EJ, Quinn JA, Bland KI, Frackelton Jr AR 2000 Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14:1649-1660
40. Alexaki VI, Charalampopoulos I, Kampa M, Vassalou H, Theodoropoulos P, Stathopoulos EN, Hatzoglou A, Gravanis A, Castanas E 2004 Estrogen exerts neuroprotective effects via membrane estrogen receptors and rapid Akt/NOS activation. FASEB J 18:1594-1596
41. Toran-Allerand CD 2004 Estrogen and the brain: beyond ER-α and ER-β. Exp Gerontol 39:1579-1586
42. McInerney EM, Katzenellenbogen BS 1996 Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation. J Biol Chem 271:24172-24178
43. Sabbah M, Courilleau D, Mester J, Redeuilh G 1999 Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element. Proc Natl Acad Sci USA 28:11217-21122
44. Kushner PJ, Agard DA, Greene GL, Scanlan TS, Shiau AK, Uht RM, Webb P 2000 Estrogen receptor pathways to AP-1. J Steroid Biochem Mol Biol 74: 311-317
45. Safe S 2001 Transcriptional activation of genes by 17β-estradiol through estrogen receptor-Spl interactions. Vitam Horm 62:231-252
46. Webb P, Nguyen P, Valentine C, Lopez GN, Kwok GR, McInerney E, Katzenellenbogen BS, Enmark E, Gustafsson JA, Nilsson S, Kushner PJ 1999 The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions. Mol Endocrinol 13:1672-1685
47. Kim K, Thu N, Saville B, Safe S 2003 Domains of estrogen receptor α (ERα) required for ERα/Spl-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells. Mol Endocrinol 17:804-817
48. LiL, Haynes MP, Bender JR2003 Plasma membrane localization and function of the estrogen receptor α variant (ER46) in human endothelial cells. Proc Natl Acad Sci USA 100:4807-4812
49. Bjornstrom L, Sjoberg M 2002 Mutations in the estrogen receptor DNA- binding domain discriminate between the classical mechanism of action and cross-talk with Stat5b and activating protein 1 (AP-1). J Biol Chem 277:48479-48483
50. Kumar V, Green S, Stack G, Berry M, Jin JR, Chambon P 1987 Functional domains of the human estrogen receptor. Cell 51:941-951
51. Teyssier C, Belguise K, Galtier F, Chalbos D 2001 Characterization of the physical interaction between estrogen receptor α and JUN proteins. J Biol Chem 276:36361-36369