Expression of Neuronal Trace Amine-associated Receptor (Taar) mRNAs in Leukocytes

Journal of Neuroimmunology

Volumn 192, Issue 1-2, 2007, Pages 21-30

  Nelson, Daniel A ^a   Tolbert, Melanie D ^a   Singh, Sam J ^a   Bost, Kenneth L ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

3,4 methylenedioxymethamphetamine; Ecstasy; Human peripheral blood lymphocyte; Mouse B cell; Mouse bone marrow; Mouse dendritic cell; Mouse macrophage; Trace amine associated receptor

Indexed keywords

LIPOPOLYSACCHARIDE; MESSENGER RNA; N ETHYL 3,4 METHYLENEDIOXYAMPHETAMINE; PHYTOHEMAGGLUTININ; PROTEIN TRACE AMINE ASSOCIATED RECEPTOR 1; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; LEUKOCYTE; MOUSE; NATURAL KILLER CELL; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BONE MARROW CELLS; DENDRITIC CELLS; FEMALE; GENE EXPRESSION; HUMANS; INTERLEUKIN-6; LEUKOCYTE COUNT; LEUKOCYTES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHADINOVIRUS; RNA, MESSENGER; TIME FACTORS;

EID: 36749054625     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.08.006     Document Type: Article

References (54)

1. Battaglia G., Brooks B.P., Kulsakdinun C., and De Souza E.B. Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites. Eur. J. Pharmacol. 149 (1988) 159-163
2. Berry M.D. Mammalian central nervous system trace amines. Pharmacologic amphetamines, physiologic neuromodulators. J. Neurochem. 90 (2004) 257-271
3. Borowsky B., Adham N., Jones K.A., Raddatz R., Artymyshyn R., Ogozalek K.L., Durkin M.M., Lakhlani P.P., Bonini J.A., Pathirana S., Boyle N., Pu X., Kouranova E., Lichtblau H., Ochoa F.Y., Branchek T.A., and Gerald C. Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 8966-8971
4. Bowman C.C., and Bost K.L. Cyclooxygenase-2-mediated prostaglandin E2 production in mesenteric lymph nodes and in cultured macrophages and dendritic cells after infection with Salmonella. J. Immunol. 172 (2004) 2469-2475
5. Branchek T.A., and Blackburn T.P. Trace amine receptors as targets for novel therapeutics: legend, myth and fact. Curr. Opin. Pharmacol. 3 (2003) 90-97
6. Bunzow J.R., Sonders M.S., Arttamangkul S., Harrison L.M., Zhang G., Quigley D.I., Darland T., Suchland K.L., Pasumamula S., Kennedy J.L., Olson S.B., Magenis R.E., Amara S.G., and Grandy D.K. Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor. Mol. Pharmacol. 60 (2001) 1181-1188
7. Burchett S.A., and Hicks T.P. The mysterious trace amines: protean neuromodulators of synaptic transmission in mammalian brain. Prog. Neurobiol. 79 (2006) 223-246
8. Cloez-Tayarani I., Kayyali U.S., Fanburg B.L., and Cavaillon J.M. 5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors. Life Sci. 76 (2004) 429-443
9. Cloez-Tayarani I., Petit-Bertron A.F., Venters H.D., and Cavaillon J.M. Differential effect of serotonin on cytokine production in lipopolysaccharide-stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors. Int. Immunol. 15 (2003) 233-240
10. Connor T.J. Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): a stressor on the immune system. Immunology 111 (2004) 357-367
11. Connor T.J., Connelly D.B., and Kelly J.P. Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG2a and IFN-gamma production. Immunol. Lett. 78 (2001) 67-73
12. Connor T.J., Harkin A., and Kelly J.P. Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10. J. Pharmacol. Exp. Ther. 312 (2005) 134-143
13. Connor T.J., Kelly J.P., and Leonard B.E. An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats. Immunopharmacology 46 (2000) 223-235
14. Connor T.J., Kelly J.P., McGee M., and Leonard B.E. Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1beta and TNF-alpha secretion following an in vivo lipopolysaccharide challenge. Life Sci. 67 (2000) 1601-1612
15. Downing J. The psychological and physiological effects of MDMA on normal volunteers. J. Psychoact. Drugs 18 (1986) 335-340
16. Durk T., Panther E., Muller T., Sorichter S., Ferrari D., Pizzirani C., Di Virgilio F., Myrtek D., Norgauer J., and Idzko M. 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. Int. Immunol. 17 (2005) 599-606
17. Elsawa S.F., and Bost K.L. Murine gamma-herpesvirus-68-induced IL-12 contributes to the control of latent viral burden, but also contributes to viral-mediated leukocytosis. J. Immunol. 172 (2004) 516-524
18. Freese T.E., Miotto K., and Reback C.J. The effects and consequences of selected club drugs. J. Subst. Abuse Treat. 23 (2002) 151-156
19. Gahlinger P.M. Club drugs: MDMA, gamma-hydroxybutyrate (GHB), rohypnol, and ketamine. Am. Fam. Phys. 69 (2004) 2619-2626
20. Gasper-Smith N., Marriott I., and Bost K.L. Murine {gamma}-herpesvirus 68 limits naturally occurring CD4+ CD25+ T regulatory cell activity following infection. J. Immunol. 177 (2006) 4670-4678
21. Gasper-Smith N., Singh S., and Bost K.L. Limited IL-6 production following infection with murine gammaherpesvirus 68. Arch. Virol. 151 (2006) 1423-1429
22. Gloriam D.E., Bjarnadottir T.K., Yan Y.L., Postlethwait J.H., Schioth H.B., and Fredriksson R. The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish. Mol. Phylogenet. Evol. 35 (2005) 470-482
23. Han D.D., and Gu H.H. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs. BMC Pharmacol. 6 (2006) 6
24. Idzko M., Panther E., Stratz C., Muller T., Bayer H., Zissel G., Durk T., Sorichter S., Di Virgilio F., Geissler M., Fiebich B., Herouy Y., Elsner P., Norgauer J., and Ferrari D. The serotoninergic receptors of human dendritic cells: identification and coupling to cytokine release. J. Immunol. 172 (2004) 6011-6019
25. Inaba K., Inaba M., Romani N., Aya H., Deguchi M., Ikehara S., Muramatsu S., and Steinman R.M. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176 (1992) 1693-1702
26. Kalant H. The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs. Cmaj 165 (2001) 917-928
27. Kramer H.K., Poblete J.C., and Azmitia E.C. Activation of protein kinase C (PKC) by 3,4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter. Neuropsychopharmacology 17 (1997) 117-129
28. Landry M.J. MDMA: a review of epidemiologic data. J. Psychoact. Drugs 34 (2002) 163-169
29. Lewin A.H. Receptors of mammalian trace amines. AAPS J. 8 (2006) E138-E145
30. Lindemann L., and Hoener M.C. A renaissance in trace amines inspired by a novel GPCR family. Trends Pharmacol. Sci. 26 (2005) 274-281
31. Lindemann L., Ebeling M., Kratochwil N.A., Bunzow J.R., Grandy D.K., and Hoener M.C. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Genomics 85 (2005) 372-385
32. Marriott I., Hammond T.G., Thomas E.K., and Bost K.L. Salmonella efficiently enter and survive within cultured CD11c+ dendritic cells initiating cytokine expression. Eur. J. Immunol. 29 (1999) 1107-1115
33. Monte D., Baert J.L., Defossez P.A., de Launoit Y., and Stehelin D. Molecular cloning and characterization of human ERM, a new member of the Ets family closely related to mouse PEA3 and ER81 transcription factors. Oncogene 9 (1994) 1397-1406
34. Mossner R., and Lesch K.P. Role of serotonin in the immune system and in neuroimmune interactions. Brain Behav. Immun. 12 (1998) 249-271
35. Nash J.F., Roth B.L., Brodkin J.D., Nichols D.E., and Gudelsky G.A. Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors. Neurosci. Lett. 177 (1994) 111-115
36. Nelson D.A., Marriott I., and Bost K.L. Expression of hemokinin 1 mRNA by murine dendritic cells. J. Neuroimmunol. 155 (2004) 94-102
37. Pacifici R., Zuccaro P., Farre M., Pichini S., Di Carlo S., Roset P.N., Lopez C.H., Ortuno J., Segura J., Cami J., and de la Torre R. Immunomodulating activity of MDMA. Ann. N. Y. Acad. Sci. 914 (2000) 215-224
38. Pacifici R., Zuccaro P., Farre M., Pichini S., Di Carlo S., Roset P.N., Ortuno J., Pujadas M., Bacosi A., Menoyo E., Segura J., and de la Torre R. Effects of repeated doses of MDMA ("ecstasy") on cell-mediated immune response in humans. Life Sci. 69 (2001) 2931-2941
39. Pacifici R., Zuccaro P., Hernandez Lopez C., Pichini S., Di Carlo S., Farre M., Roset P.N., Ortuno J., Segura J., and Torre R.L. Acute effects of 3,4-methylenedioxymethamphetamine alone and in combination with ethanol on the immune system in humans. J. Pharmacol. Exp. Ther. 296 (2001) 207-215
40. Pacifici R., Zuccaro P., Farre M., Pichini S., Di Carlo S., Roset P.N., Palmi I., Ortuno J., Menoyo E., Segura J., and de la Torre R. Cell-mediated immune response in MDMA users after repeated dose administration: studies in controlled versus noncontrolled settings. Ann. N. Y. Acad. Sci. 965 (2002) 421-433
41. Pacifici R., Pichini S., Zuccaro P., Farre M., Segura M., Ortuno J., Di Carlo S., Bacosi A., Roset P.N., Segura J., and de la Torre R. Paroxetine inhibits acute effects of 3,4-methylenedioxymethamphetamine on the immune system in humans. J. Pharmacol. Exp. Ther. 309 (2004) 285-292
42. Parrott A.C., Buchanan T., Scholey A.B., Heffernan T., Ling J., and Rodgers J. Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users. Hum. Psychopharmacol. 17 (2002) 309-312
43. Partilla J.S., Dempsey A.G., Nagpal A.S., Blough B.E., Baumann M.H., and Rothman R.B. Interaction of amphetamines and related compounds at the vesicular monoamine transporter. J. Pharmacol. Exp. Ther. 319 (2006) 237-246
44. Premont R.T., Gainetdinov R.R., and Caron M.G. Following the trace of elusive amines. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 9474-9475
45. Pubill D., Canudas A.M., Pallas M., Camins A., Camarasa J., and Escubedo E. Different glial response to methamphetamine-and methylenedioxymethamphetamine-induced neurotoxicity. Naunyn-Schmiedebergs Arch. Pharmacol. 367 (2003) 490-499
46. Ropero-Miller J.D., and Goldberger B.A. Recreational drugs. Current trends in the 90s. Clin. Lab. Med. 18 (1998) 727-746 x
47. Rudnick G., and Wall S.C. The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 1817-1821
48. Scheicher C., Mehlig M., Zecher R., and Reske K. Dendritic cells from mouse bone marrow: in vitro differentiation using low doses of recombinant granulocyte-macrophage colony-stimulating factor. J. Immunol. Methods 154 (1992) 253-264
49. Sklar M.D., Tereba A., Chen B.D., and Walker W.S. Transformation of mouse bone marrow cells by transfection with a human oncogene related to c-myc is associated with the endogenous production of macrophage colony stimulating factor 1. J. Cell. Physiol. 125 (1985) 403-412
50. Smith K.M., Larive L.L., and Romanelli F. Club drugs: methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate. Am. J. Health-Syst. Pharm. 59 (2002) 1067-1076
51. Stefulj J., Jernej B., Cicin-Sain L., Rinner I., and Schauenstein K. mRNA expression of serotonin receptors in cells of the immune tissues of the rat. Brain Behav. Immun. 14 (2000) 219-224
52. Thomas D.M., Dowgiert J., Geddes T.J., Francescutti-Verbeem D., Liu X., and Kuhn D.M. Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines. Neurosci. Lett. 367 (2004) 349-354
53. Verrico C.D., Miller G.M., and Madras B.K. MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment. Psychopharmacology (Berl) 189 (2007) 489-503
54. Zucchi R., Chiellini G., Scanlan T.S., and Grandy D.K. Trace amine-associated receptors and their ligands. Br. J. Pharmacol. 149 (2006) 967-978