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Volumn 98, Issue 3, 2013, Pages 455-463

Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ENHANCED GREEN FLUORESCENT PROTEIN; FERRITIN; FERROPORTIN; HEPCIDIN; IRON; MYC PROTEIN; TRANSFERRIN; CATION TRANSPORT PROTEIN; HYBRID PROTEIN; METAL TRANSPORTING PROTEIN 1; MUTANT PROTEIN;

EID: 84874537127     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.066530     Document Type: Article
Times cited : (23)

References (68)
  • 1
    • 0033861745 scopus 로고    scopus 로고
    • A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
    • McKie AT, Marciani P, Rolfs A, Brennan K, Wehr K, Barrow D, et al. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell. 2000;5(2):299-309.
    • (2000) Mol Cell , vol.5 , Issue.2 , pp. 299-309
    • McKie, A.T.1    Marciani, P.2    Rolfs, A.3    Brennan, K.4    Wehr, K.5    Barrow, D.6
  • 2
    • 0034677467 scopus 로고    scopus 로고
    • Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
    • Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 2000;403(6771):776-81.
    • (2000) Nature , vol.403 , Issue.6771 , pp. 776-781
    • Donovan, A.1    Brownlie, A.2    Zhou, Y.3    Shepard, J.4    Pratt, S.J.5    Moynihan, J.6
  • 3
    • 0034733635 scopus 로고    scopus 로고
    • A novel mammalian iron-regulated protein involved in intracellular iron metabolism
    • Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem. 2000;275(26):19906-12.
    • (2000) J Biol Chem , vol.275 , Issue.26 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 4
    • 10744219518 scopus 로고    scopus 로고
    • Expression of the iron transporter ferroportin in synaptic vesicles and the blood brain barrier
    • Wu LJ, Leenders AG, Cooperman S, Meyron-Holtz E, Smith S, Land W, et al. Expression of the iron transporter ferroportin in synaptic vesicles and the blood brain barrier. Brain Res. 2004;1001(1-2):108-17.
    • (2004) Brain Res , vol.1001 , Issue.1-2 , pp. 108-117
    • Wu, L.J.1    Leenders, A.G.2    Cooperman, S.3    Meyron-Holtz, E.4    Smith, S.5    Land, W.6
  • 5
    • 27744490839 scopus 로고    scopus 로고
    • Glucose-induced regulation of novel iron transporters in vascular endothelial cell dysfunction
    • Khan ZA, Farhangkhoee H, Barbin YP, Adams PC, Chakrabarti S. Glucose-induced regulation of novel iron transporters in vascular endothelial cell dysfunction. Free Radic Res. 2005;39(11):1203-10.
    • (2005) Free Radic Res , vol.39 , Issue.11 , pp. 1203-1210
    • Khan, Z.A.1    Farhangkhoee, H.2    Barbin, Y.P.3    Adams, P.C.4    Chakrabarti, S.5
  • 6
    • 28444488323 scopus 로고    scopus 로고
    • Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin
    • Delaby C, Pilard N, Goncalves AS, Beaumont C, Canonne-Hergaux F. Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin. Blood. 2005;106(12):3979-84.
    • (2005) Blood , vol.106 , Issue.12 , pp. 3979-3984
    • Delaby, C.1    Pilard, N.2    Goncalves, A.S.3    Beaumont, C.4    Canonne-Hergaux, F.5
  • 7
    • 0345688910 scopus 로고    scopus 로고
    • Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages
    • Knutson MD, Vafa MR, Haile DJ, Wessling Resnick M. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood. 2003;102(12):4191-7.
    • (2003) Blood , vol.102 , Issue.12 , pp. 4191-4197
    • Knutson, M.D.1    Vafa, M.R.2    Haile, D.J.3    Wessling, R.M.4
  • 8
    • 1542357700 scopus 로고    scopus 로고
    • Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux
    • Chung J, Haile DJ, Wessling-Resnick M. Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux. Proc Natl Acad Sci USA. 2004;101(9):2700-5.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.9 , pp. 2700-2705
    • Chung, J.1    Haile, D.J.2    Wessling-Resnick, M.3
  • 9
    • 33750133047 scopus 로고    scopus 로고
    • Regulation of iron metabolism by hepcidin
    • Nemeth E, Ganz T. Regulation of iron metabolism by hepcidin. Annu Rev Nutr. 2006;26:323-42.
    • (2006) Annu Rev Nutr , vol.26 , pp. 323-342
    • Nemeth, E.1    Ganz, T.2
  • 10
    • 41349106987 scopus 로고    scopus 로고
    • Autocrine formation of hepcidin induces iron retention in human monocytes
    • Theurl I, Theurl M, Seifert M, Mair S, Nairz M, Rumpold H, et al. Autocrine formation of hepcidin induces iron retention in human monocytes. Blood. 2008;111(4): 2392-9.
    • (2008) Blood , vol.111 , Issue.4 , pp. 2392-2399
    • Theurl, I.1    Theurl, M.2    Seifert, M.3    Mair, S.4    Nairz, M.5    Rumpold, H.6
  • 11
    • 77955508573 scopus 로고    scopus 로고
    • Hereditary hemochromatosis: Pathogenesis, diagnosis, and treatment
    • Pietrangelo A. Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment. Gastroenterology. 2010;139(2):393-408, e1-2.
    • (2010) Gastroenterology , vol.139 , Issue.2 , pp. 393-408
    • Pietrangelo, A.1
  • 13
    • 67349113791 scopus 로고    scopus 로고
    • (Pre)analytical imprecision, between-subject variability, and daily variations in serum and urine hepcidin: Implications for clinical studies
    • Kroot JJ, Hendriks JC, Laarakkers CM, Klaver SM, Kemna EH, Tjalsma H, et al. (Pre)analytical imprecision, between-subject variability, and daily variations in serum and urine hepcidin: implications for clinical studies. Anal Biochem. 2009;389(2): 124-9.
    • (2009) Anal Biochem , vol.389 , Issue.2 , pp. 124-129
    • Kroot, J.J.1    Hendriks, J.C.2    Laarakkers, C.M.3    Klaver, S.M.4    Kemna, E.H.5    Tjalsma, H.6
  • 16
    • 10744232713 scopus 로고    scopus 로고
    • Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene
    • Gordeuk VR, Caleffi A, Corradini E, Ferrara F, Jones RA, Castro O, et al. Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene. Blood Cells Mol Dis. 2003;31(3):299-304.
    • (2003) Blood Cells Mol Dis , vol.31 , Issue.3 , pp. 299-304
    • Gordeuk, V.R.1    Caleffi, A.2    Corradini, E.3    Ferrara, F.4    Jones, R.A.5    Castro, O.6
  • 17
  • 18
    • 33644873239 scopus 로고    scopus 로고
    • Ferroportin (Q248H) mutations in African families with dietary iron overload
    • McNamara L, Gordeuk VR, MacPhail AP. Ferroportin (Q248H) mutations in African families with dietary iron overload. J Gastroenterol Hepatol. 2005;20(12):1855-8.
    • (2005) J Gastroenterol Hepatol , vol.20 , Issue.12 , pp. 1855-1858
    • McNamara, L.1    Gordeuk, V.R.2    Macphail, A.P.3
  • 20
    • 34047198023 scopus 로고    scopus 로고
    • Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study
    • Rivers CA, Barton JC, Gordeuk VR, Acton RT, Speechley MR, Snively BM, et al. Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study. Blood Cells Mol Dis. 2007;38(3):247-52.
    • (2007) Blood Cells Mol Dis , vol.38 , Issue.3 , pp. 247-252
    • Rivers, C.A.1    Barton, J.C.2    Gordeuk, V.R.3    Acton, R.T.4    Speechley, M.R.5    Snively, B.M.6
  • 21
    • 84862694426 scopus 로고    scopus 로고
    • Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating serum hepcidin levels in Rwandese HIV-positive women
    • Masaisa F, Breman C, Gahutu JB, Mukiibi J, Delanghe J, Philippe J. Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating serum hepcidin levels in Rwandese HIV-positive women. Ann Hematol. 2012;91(6):911-6.
    • (2012) Ann Hematol , vol.91 , Issue.6 , pp. 911-916
    • Masaisa, F.1    Breman, C.2    Gahutu, J.B.3    Mukiibi, J.4    Delanghe, J.5    Philippe, J.6
  • 22
    • 79953084701 scopus 로고    scopus 로고
    • SLC40A1 Q248H allele frequencies and associated SLC40A1 haplotypes in three West African population samples
    • Albuquerque D, Manco L, Loua KM, Arez AP, Trovoada Mde J, Relvas L, et al. SLC40A1 Q248H allele frequencies and associated SLC40A1 haplotypes in three West African population samples. Ann Hum Biol. 2011;38(3):378-81.
    • (2011) Ann Hum Biol , vol.38 , Issue.3 , pp. 378-381
    • Albuquerque, D.1    Manco, L.2    Loua, K.M.3    Arez, A.P.4    Trovoada, M.J.5    Relvas, L.6
  • 25
    • 77954144132 scopus 로고    scopus 로고
    • Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-alpha and macrophage migration inhibitory factor concentrations in African children
    • Kasvosve I, Debebe Z, Nekhai S, Gordeuk VR. Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-alpha and macrophage migration inhibitory factor concentrations in African children. Clin Chim Acta. 2010;411(17-18):1248-52.
    • (2010) Clin Chim Acta , vol.411 , Issue.17-18 , pp. 1248-1252
    • Kasvosve, I.1    Debebe, Z.2    Nekhai, S.3    Gordeuk, V.R.4
  • 27
    • 0043122919 scopus 로고    scopus 로고
    • SIFT: Predicting amino acid changes that affect protein function
    • Ng PC, Henikoff S. SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res. 2003;31(13):3812-4.
    • (2003) Nucleic Acids Res , vol.31 , Issue.13 , pp. 3812-3814
    • Ng, P.C.1    Henikoff, S.2
  • 28
    • 0036713510 scopus 로고    scopus 로고
    • Human non-synonymous SNPs: Server and survey
    • Ramensky V, Bork P, Sunyaev S. Human non-synonymous SNPs: server and survey. Nucleic Acids Res. 2002;30(17):3894-900.
    • (2002) Nucleic Acids Res , vol.30 , Issue.17 , pp. 3894-3900
    • Ramensky, V.1    Bork, P.2    Sunyaev, S.3
  • 29
    • 10744233940 scopus 로고    scopus 로고
    • Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
    • Gladwin MT, Sachdev V, Jison ML, Shizukuda Y, Plehn JF, Minter K, et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med. 2004;350(9):886-95.
    • (2004) N Engl J Med , vol.350 , Issue.9 , pp. 886-895
    • Gladwin, M.T.1    Sachdev, V.2    Jison, M.L.3    Shizukuda, Y.4    Plehn, J.F.5    Minter, K.6
  • 30
    • 33644775612 scopus 로고    scopus 로고
    • Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease
    • Kato GJ, McGowan V, Machado RF, Little JA, Taylor JT, Morris CR, et al. Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood. 2006;107(6):2279-85.
    • (2006) Blood , vol.107 , Issue.6 , pp. 2279-2285
    • Kato, G.J.1    McGowan, V.2    Machado, R.F.3    Little, J.A.4    Taylor, J.T.5    Morris, C.R.6
  • 31
    • 33746040474 scopus 로고    scopus 로고
    • N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease
    • Machado RF, Anthi A, Steinberg MH, Bonds D, Sachdev V, Kato GJ, et al. N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease. JAMA. 2006;296(3):310-8.
    • (2006) JAMA , vol.296 , Issue.3 , pp. 310-318
    • Machado, R.F.1    Anthi, A.2    Steinberg, M.H.3    Bonds, D.4    Sachdev, V.5    Kato, G.J.6
  • 32
    • 38349016795 scopus 로고    scopus 로고
    • Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease
    • Taylor JG 6th, Ackah D, Cobb C, Orr N, Percy MJ, Sachdev V, et al. Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease. Am J Hematol. 2008;83(1):6-14.
    • (2008) Am J Hematol , vol.83 , Issue.1 , pp. 6-14
    • Taylor VI, J.G.1    Ackah, D.2    Cobb, C.3    Orr, N.4    Percy, M.J.5    Sachdev, V.6
  • 33
  • 36
    • 84859173084 scopus 로고    scopus 로고
    • Mortality in adults with sickle cell disease and pulmonary hypertensio
    • Mehari A, Gladwin MT, Tian X, Machado RF, Kato GJ. Mortality in adults with sickle cell disease and pulmonary hypertension. JAMA. 2012;307(12):1254-6.
    • (2012) JAM , vol.307 , Issue.12 , pp. 1254-1256
    • Mehar, A.1    Gladwi, M.T.2    Tian, X.3    Machad, R.4    Kat, G.J.5
  • 37
    • 21544442328 scopus 로고    scopus 로고
    • Functional consequences of ferroportin 1 mutations
    • Liu XB, Yang F, Haile DJ. Functional consequences of ferroportin 1 mutations. Blood Cells Mol Dis. 2005;35(1):33-46.
    • (2005) Blood Cells Mol Dis , vol.35 , Issue.1 , pp. 33-46
    • Liu, X.B.1    Yang, F.2    Haile, D.J.3
  • 38
    • 84862002810 scopus 로고    scopus 로고
    • Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination
    • Qiao B, Sugianto P, Fung E, Del-Castillo, Rueda A, Moran-Jimenez MJ, Ganz T, et al. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metab. 2012;15(6):918-24.
    • (2012) Cell Metab , vol.15 , Issue.6 , pp. 918-924
    • Qiao, B.1    Sugianto, P.2    Fung, E.3    Del-Castillo, R.A.4    Moran-Jimenez, M.J.5    Ganz, T.6
  • 39
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306(5704):2090-3.
    • (2004) Science , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6
  • 40
    • 0036791486 scopus 로고    scopus 로고
    • The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
    • Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110(7):1037-44.
    • (2002) J Clin Invest , vol.110 , Issue.7 , pp. 1037-1044
    • Nicolas, G.1    Chauvet, C.2    Viatte, L.3    Danan, J.L.4    Bigard, X.5    Devaux, I.6
  • 43
    • 17944380796 scopus 로고    scopus 로고
    • Autosomaldominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
    • Montosi G, Donovan A, Totaro A, Garuti C, Pignatti E, Cassanelli S, et al. Autosomaldominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest. 2001;108 (4):619-23.
    • (2001) J Clin Invest , vol.108 , Issue.4 , pp. 619-623
    • Montosi, G.1    Donovan, A.2    Totaro, A.3    Garuti, C.4    Pignatti, E.5    Cassanelli, S.6
  • 46
    • 0016253111 scopus 로고
    • Hemolysis in sickle cell disease
    • Bensinger TA, Gillette PN. Hemolysis in sickle cell disease. Arch Intern Med. 1974;133(4):624-31.
    • (1974) Arch Intern Med , vol.133 , Issue.4 , pp. 624-631
    • Bensinger, T.A.1    Gillette, P.N.2
  • 47
    • 84857179124 scopus 로고    scopus 로고
    • Renal disease in adult Nigerians with sickle cell anemia: A report of prevalence, clinical features and risk factors
    • Bolarinwa RA, Akinlade KS, Kuti MA, Olawale OO, Akinola NO. Renal disease in adult Nigerians with sickle cell anemia: a report of prevalence, clinical features and risk factors. Saudi J Kidney Dis Transpl. 2012;23(1):171-5.
    • (2012) Saudi J Kidney Dis Transpl , vol.23 , Issue.1 , pp. 171-175
    • Bolarinwa, R.A.1    Akinlade, K.S.2    Kuti, M.A.3    Olawale, O.O.4    Akinola, N.O.5
  • 48
    • 33846279380 scopus 로고    scopus 로고
    • Deconstructing sickle cell disease: Reappraisal of the role of hemolysis in the development of clinical subphenotypes
    • Kato GJ, Gladwin MT, Steinberg MH. Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes. Blood Rev. 2007;21(1):37-47.
    • (2007) Blood Rev , vol.21 , Issue.1 , pp. 37-47
    • Kato, G.J.1    Gladwin, M.T.2    Steinberg, M.H.3
  • 49
    • 33745699067 scopus 로고    scopus 로고
    • Cerebrovascular disease associated with sickle cell pulmonary hypertension
    • Kato GJ, Hsieh M, Machado R, Taylor Jt, Little J, Butman JA, et al. Cerebrovascular disease associated with sickle cell pulmonary hypertension. Am J Hematol. 2006;81(7):503-10.
    • (2006) Am J Hematol , vol.81 , Issue.7 , pp. 503-510
    • Kato, G.J.1    Hsieh, M.2    Machado, R.3    Taylor, J.T.4    Little, J.5    Butman, J.A.6
  • 50
    • 21444441271 scopus 로고    scopus 로고
    • Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease
    • Morris CR, Kato GJ, Poljakovic M, Wang X, Blackwelder WC, Sachdev V, et al. Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA. 2005;294(1):81-90.
    • (2005) JAMA , vol.294 , Issue.1 , pp. 81-90
    • Morris, C.R.1    Kato, G.J.2    Poljakovic, M.3    Wang, X.4    Blackwelder, W.C.5    Sachdev, V.6
  • 52
    • 33846338501 scopus 로고    scopus 로고
    • Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease
    • Sachdev V, Machado RF, Shizukuda Y, Rao YN, Sidenko S, Ernst I, et al. Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease. J Am Coll Cardiol. 2007;49(4):472-9.
    • (2007) J Am Coll Cardiol , vol.49 , Issue.4 , pp. 472-479
    • Sachdev, V.1    Machado, R.F.2    Shizukuda, Y.3    Rao, Y.N.4    Sidenko, S.5    Ernst, I.6
  • 53
    • 0031043376 scopus 로고    scopus 로고
    • Cardiopulmonary pathology in patients with sleep apnea/obesity hypoventilation syndrome
    • Ahmed Q, Chung-Park M, Tomashefski JF, Jr. Cardiopulmonary pathology in patients with sleep apnea/obesity hypoventilation syndrome. Hum Pathol. 1997;28(3):264-9.
    • (1997) Hum Pathol , vol.28 , Issue.3 , pp. 264-269
    • Ahmed, Q.1    Chung-Park, M.2    Tomashefski Jr., J.F.3
  • 54
    • 34347269612 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with sickle cell/beta thalassemia: Incidence and correlation with serum N-terminal probrain natriuretic peptide concentrations
    • Voskaridou E, Tsetsos G, Tsoutsias A, Spyropoulou E, Christoulas D, Terpos E. Pulmonary hypertension in patients with sickle cell/beta thalassemia: incidence and correlation with serum N-terminal probrain natriuretic peptide concentrations. Haematologica. 2007;92(6):738-43.
    • (2007) Haematologica , vol.92 , Issue.6 , pp. 738-743
    • Voskaridou, E.1    Tsetsos, G.2    Tsoutsias, A.3    Spyropoulou, E.4    Christoulas, D.5    Terpos, E.6
  • 55
    • 79960101398 scopus 로고    scopus 로고
    • A hemodynamic study of pulmonary hypertension in sickle cell disease
    • Parent F, Bachir D, Inamo J, Lionnet F, Driss F, Loko G, et al. A hemodynamic study of pulmonary hypertension in sickle cell disease. N Engl J Med. 2011;365(1):44-53.
    • (2011) N Engl J Med , vol.365 , Issue.1 , pp. 44-53
    • Parent, F.1    Bachir, D.2    Inamo, J.3    Lionnet, F.4    Driss, F.5    Loko, G.6
  • 56
    • 81255174878 scopus 로고    scopus 로고
    • Pulmonary hypertension diagnosed by right heart catheterization in sickle cell disease
    • Fonseca GH, Souza R, Salemi VC, Jardim CV, Gualandro SF. Pulmonary hypertension diagnosed by right heart catheterization in sickle cell disease. Eur Respir J. 2012;39(1): 112-8.
    • (2012) Eur Respir J , vol.39 , Issue.1 , pp. 112-118
    • Fonseca, G.H.1    Souza, R.2    Salemi, V.C.3    Jardim, C.V.4    Gualandro, S.F.5
  • 57
    • 33644798028 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced iron sequestration and oxidative stress in human endothelial cells
    • Nanami M, Ookawara T, Otaki Y, Ito K, Moriguchi R, Miyagawa K, et al. Tumor necrosis factor-alpha-induced iron sequestration and oxidative stress in human endothelial cells. Arterioscler Thromb Vasc Biol. 2005;25(12):2495-501.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.12 , pp. 2495-2501
    • Nanami, M.1    Ookawara, T.2    Otaki, Y.3    Ito, K.4    Moriguchi, R.5    Miyagawa, K.6
  • 59
    • 84862002810 scopus 로고    scopus 로고
    • Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination
    • Qiao B, Sugianto P, Fung E, del-Castillo, Rueda A, Moran-Jimenez M-J, Ganz T, et al. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metab. 2012;15(6):918-24.
    • (2012) Cell Metab , vol.15 , Issue.6 , pp. 918-924
    • Qiao, B.1    Sugianto, P.2    Fung, E.3    Del-Castillo, R.A.4    Moran-Jimenez, M.-J.5    Ganz, T.6
  • 60
    • 50549095186 scopus 로고    scopus 로고
    • Clinical, pathological, and molecular correlates in ferroportin disease: A study of two novel mutations
    • Girelli D, De Domenico I, Bozzini C, Campostrini N, Busti F, Castagna A, et al. Clinical, pathological, and molecular correlates in ferroportin disease: a study of two novel mutations. J Hepatol. 2008;49(4):664-71.
    • (2008) J Hepatol , vol.49 , Issue.4 , pp. 664-671
    • Girelli, D.1    De Domenico, I.2    Bozzini, C.3    Campostrini, N.4    Busti, F.5    Castagna, A.6
  • 61
    • 67651087324 scopus 로고    scopus 로고
    • The molecular basis of hepcidin-resistant hereditary hemochromatosis
    • Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, et al. The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 2009;114 (2):437-43.
    • (2009) Blood , vol.114 , Issue.2 , pp. 437-443
    • Fernandes, A.1    Preza, G.C.2    Phung, Y.3    De Domenico, I.4    Kaplan, J.5    Ganz, T.6
  • 65
    • 13844270538 scopus 로고    scopus 로고
    • Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features
    • Sham RL, Phatak PD, West C, Lee P, Andrews C, Beutler E. Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features. Blood Cells Mol Dis. 2005;34(2):157-61.
    • (2005) Blood Cells Mol Dis , vol.34 , Issue.2 , pp. 157-161
    • Sham, R.L.1    Phatak, P.D.2    West, C.3    Lee, P.4    Andrews, C.5    Beutler, E.6
  • 66
    • 10744219904 scopus 로고    scopus 로고
    • Novel mutation in ferroportin 1 gene is associated with autosomal dominant iron overload
    • Jouanolle AM, Douabin-Gicquel V, Halimi C, Loreal O, Fergelot P, Delacour T, et al. Novel mutation in ferroportin 1 gene is associated with autosomal dominant iron overload. J Hepatol. 2003;39(2):286-9.
    • (2003) J Hepatol , vol.39 , Issue.2 , pp. 286-289
    • Jouanolle, A.M.1    Douabin-Gicquel, V.2    Halimi, C.3    Loreal, O.4    Fergelot, P.5    Delacour, T.6
  • 67
    • 84860814886 scopus 로고    scopus 로고
    • Mild iron overload in an African American man with SLC40A1 D270V
    • Lee PL, Gaasterland T, Barton JC. Mild iron overload in an African American man with SLC40A1 D270V. Acta Haematol. 2012; 128(1):28-32.
    • (2012) Acta Haematol , vol.128 , Issue.1 , pp. 28-32
    • Lee, P.L.1    Gaasterland, T.2    Barton, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.