Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease

American Journal of Hematology

Volumn 83, Issue 1, 2008, Pages 6-14

  Taylor VI, James G ^a   Ackah, Diana ^a   Cobb, Crystal ^a   Orr, Nick ^b   Percy, Melanie J ^c   Sachdev, Vandana ^a   Machado, Roberto ^a   Castro, Oswaldo ^d   Kato, Gregory J ^a,e   Chanock, Stephen J ^b   Gladwin, Mark T ^a,e  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c BELFAST CITY HOSPITAL   (United Kingdom)

^d HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; HEMOGLOBIN; HEMOGLOBIN C; HEMOGLOBIN S; HEMOGLOBIN VARIANT; NITRIC OXIDE;

ADULT; ALPHA THALASSEMIA; ARTICLE; CHROMOSOME 11; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; FOLLOW UP; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENOTYPE; HAPLOTYPE; HBB GENE; HEMOLYSIS; HETEROZYGOSITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOZYGOSITY; HUMAN; IRON OVERLOAD; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PHENOTYPE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RISK ASSESSMENT; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGE DISTRIBUTION; ALLELES; ALPHA-THALASSEMIA; ANEMIA, SICKLE CELL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMOSOMES, HUMAN, PAIR 11; COHORT STUDIES; FALSE POSITIVE REACTIONS; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HEMOGLOBINS; HUMANS; HYPERTENSION, PULMONARY; MALE; MUTATION; PHENOTYPE; POLYMORPHISM, GENETIC; RISK FACTORS; SURVIVAL RATE;

EID: 38349016795     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21035     Document Type: Article

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