Establishment of the cumulative margin of exposure for a group of polychlorinated biphenyl (PCB) congeners using an improved approach that accounts for both variability and uncertainty

Regulatory Toxicology and Pharmacology

Volumn 65, Issue 3, 2013, Pages 325-333

  Kalantari, Fereshteh ^a   Bergkvist, Charlotte ^d   Berglund, Marika ^a   Fattore, Elena ^b   Glynn, Anders ^c   Håkansson, Helen ^a   Sand, Salomon ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c National Food Agency   (Sweden)

^d EUROPEAN FOOD SAFETY AUTHORITY   (Italy)

Author keywords

Benchmark dose; Cumulative risk assessment; Dietary exposure; Health based guidance value; Hepatic vitamin A; Margin of exposure; Polychlorinated biphenyls; Retinoid system

Indexed keywords

POLYCHLORINATED BIPHENYL DERIVATIVE; RETINOID;

ARTICLE; CONTROLLED STUDY; DIET; EXPOSURE; FEMALE; HUMAN; LIVER LEVEL; MALE; MARGIN OF EXPOSURE; MATHEMATICAL PARAMETERS; PRIORITY JOURNAL; RISK ASSESSMENT; SEX DIFFERENCE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BENCHMARKING; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; FOOD CONTAMINATION; HUMANS; MALE; MIDDLE AGED; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SEX FACTORS; UNCERTAINTY; YOUNG ADULT;

EID: 84874521461     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.01.005     Document Type: Article

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