Arabidopsis A BOUT de SOUFFLE is a putative mitochondrial transporter involved in photorespiratory metabolism and is required for meristem growth at ambient CO2 levels

Plant Journal

Volumn 73, Issue 5, 2013, Pages 836-849

  Eisenhut, Marion ^a   Planchais, Severine ^b   Cabassa, Cécile ^b   Guivarc'H, Anne ^b   Justin, Anne Marie ^b   Taconnat, Ludivine ^c   Renou, Jean Pierre ^c   Linka, Marc ^a   Gagneul, David ^a,e   Timm, Stefan ^d   Bauwe, Hermann ^d   Carol, Pierre ^b   Weber, Andreas P M ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b SORBONNE UNIVERSITÉ   (France)

^c CNRS   (France)

^d UNIVERSITY OF ROSTOCK   (Germany)

^e UNIV LILLE   (France)

Author keywords

Arabidopsis; meristem; metabolite; mitochondria; photorespiration; transport protein

Indexed keywords

APICAL MERISTEMS; ARABIDOPSIS; CELL DIVISIONS; COMPENSATION POINTS; DECARBOXYLASES; ELEVATED CO; GROWTH ARREST; KNOCKOUT MUTANT; LEAF TISSUES; MERISTEM; METABOLIC FLUX; METABOLIC PATHWAYS; MITOCHONDRIAL CARRIER; OXYGENIC PHOTOSYNTHETIC ORGANISMS; P-PROTEIN; PHOTORESPIRATION; PHOTORESPIRATORY GENES; SHOOT APICAL MERISTEMS; SPECIFIC SUBSTRATES; TRANSCRIPTOMES; TRANSPORT PROTEINS; TRANSPORTER PROTEINS;

AMINO ACIDS; CELL PROLIFERATION; CYTOLOGY; GENES; METABOLISM; METABOLITES; MITOCHONDRIA; PHYSIOLOGY; PLANTS (BOTANY); PROTEINS; TISSUE;

CARBON DIOXIDE;

A BOUT DE SOUFFLE PROTEIN, ARABIDOPSIS; AMINO ACID; ARABIDOPSIS PROTEIN; CARBON DIOXIDE; CARRIER PROTEIN; GLYCINE; GLYCINE DEHYDROGENASE (DECARBOXYLATING); MITOCHONDRIAL PROTEIN;

ARABIDOPSIS; ARTICLE; CELL RESPIRATION; CYTOLOGY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETIC COMPLEMENTATION; GENETICS; LIGHT; MERISTEM; METABOLISM; MITOCHONDRION; MUTATION; OXIDATION REDUCTION REACTION; PHOTOSYNTHESIS; PHYSIOLOGY; PLANT LEAF; RADIATION EXPOSURE; SEEDLING; TRANSGENIC PLANT;

AMINO ACIDS; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARBON DIOXIDE; CELL RESPIRATION; GENE EXPRESSION PROFILING; GENETIC COMPLEMENTATION TEST; GLYCINE; GLYCINE DEHYDROGENASE (DECARBOXYLATING); LIGHT; MEMBRANE TRANSPORT PROTEINS; MERISTEM; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATION-REDUCTION; PHOTOSYNTHESIS; PLANT LEAVES; PLANTS, GENETICALLY MODIFIED; SEEDLING;

ARABIDOPSIS;

EID: 84874502626     PISSN: 09607412     EISSN: 1365313X     Source Type: Journal    
DOI: 10.1111/tpj.12082     Document Type: Article

References (85)

1. Barton, M.K., and, Poethig, R.S., (1993) Formation of the shoot apical meristem in Arabidopsis thaliana: an analysis of development in the wild type and in the shoot meristemless mutant. Development, 119, 823-881.
2. Bauwe, H., Hagemann, M., Kern, R., and, Timm, S., (2012) Photorespiration has a dual origin and manifold links to central metabolism. Curr. Opin. Plant Biol. 15, 269-275.
3. Bedhomme, M., Hoffmann, M., McCarthy, E.A., Gambonnet, B., Moran, R.G., Rebeille, F., and, Ravanel, S., (2005) Folate metabolism in plants: an Arabidopsis homolog of the mammalian mitochondrial folate transporter mediates folate import into chloroplasts. J. Biol. Chem. 280, 34823-34831. (Pubitemid 41504616)
4. + and contributes to optimal fatty acid degradation during storage oil mobilization. Plant J. 69, 1-13.
5. Boldt, R., Edner, C., Kolukisaoglu, U., Hagemann, M., Weckwerth, W., Wienkoop, S., Morgenthal, K., and, Bauwe, H., (2005) d -GLYCERATE 3-KINASE, the last unknown enzyme in the photorespiratory cycle in Arabidopsis, belongs to a novel kinase family. Plant Cell, 17, 2413-2420. (Pubitemid 41672956)
6. Bourdin, B., Adenier, H., and, Perrin, Y., (2007) Carnitine is associated with fatty acid metabolism in plants. Plant Physiol. Biochem. 45, 926-931. (Pubitemid 350138445)
7. Bouvier, F., Linka, N., Isner, J.-.C., Mutterer, J., Weber, A.P.M., and, Camara, B., (2006) Arabidopsis SAMT1 defines a plastid transporter regulating plastid biogenesis and plant development. Plant Cell, 18, 3088-3105. (Pubitemid 46013278)
8. Bowes, G., Ogren, W.L., and, Hageman, R.H., (1971) Phosphoglycolate production catalysed by ribulose diphosphate carboxylase. Biochem. Biophys. Res. Commun. 45, 716-722.
9. Boyes, D.C., Zayed, A.M., Ascenzi, R., McCaskill, A.J., Hoffman, N.E., Davis, K.R., and, Gorlach, J., (2001) Growth stage-based phenotypic analysis of Arabidopsis: a model for high throughput functional genomics in plants. Plant Cell, 13, 1499-1510. (Pubitemid 32675716)
10. Bradford, M.M., (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
11. von Caemmerer, S., (2000) Biochemical models of leaf photosynthesis. In Techniques in Plant Science Commonwealth Scientific and Industrial Research Organization Publications, Collingwood, Victoria, Australia, pp. 47-50.
12. Calvin, M., (1962) Path of carbon in photosynthesis. Science, 135, 879-889.
13. Chaubet, N., Flénet, M., Clément, B., Brignon, P., and, Gigot, C., (1996) Identification of cis-elements regulating the expression of an Arabidopsis histone H4 gene. Plant J. 10, 425-435. (Pubitemid 27108396)
14. Chen, M., and, Thelen, J.J., (2010) The plastid isoform of triose phosphate isomerase is required for the postgerminative transition from heterotrophic to autotrophic growth in Arabidopsis. Plant Cell, 22, 77-90.
15. Collakova, E., Goyer, A., Naponelli, V., Krassovskaya, I., Gregory, J.F., Hanson, A.D., and, Shachar-Hill, Y., (2008) Arabidopsis 10-formyl tetrahydrofolate deformylases are essential for photorespiration. Plant Cell, 20, 1818-1832. (Pubitemid 352844535)
16. Colõn-Carmona, A., You, R., Haimovitch-Gal, T., and, Doerner, P., (1999) Technical advance: spatio-temporal analysis of mitotic activity with a labile cyclin-GUS fusion protein. Plant J. 20, 503-508.
17. Coschigano, K.T., Melo-Oliveira, R., Lim, J., and, Coruzzi, G.M., (1998) Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation. Plant Cell, 10, 741-752. (Pubitemid 28542182)
18. Crowe, M.L., Serizet, C., Thareau, V., et al. (2003) CATMA: a complete Arabidopsis GST database. Nucleic Acids Res. 31, 156-158. (Pubitemid 36150355)
19. Douce, R., Bourguignon, J., Neuburger, M., and, Rébeillé, F., (2001) The glycine decarboxylase system: a fascinating complex. Trends Plant Sci. 4, 167-176. (Pubitemid 33145904)
20. Eisenhut, M., Ruth, W., Haimovich, M., Bauwe, H., Kaplan, A., and, Hagemann, M., (2008) The photorespiratory glycolate metabolism is essential for cyanobacteria and might have been conveyed endosymbiontically to plants. Proc. Natl Acad. Sci. USA, 105, 17199-17204.
21. Eisenhut, M., Pick, T.R., Bordych, C., and, Weber, A.P.M., (2012) Towards closing the remaining gaps in photorespiration-the essential but unexplored role of transport proteins. Plant Biol. doi: 10.1111/j.1438-8677.2012.00690.x. (Epub ahead of print).
22. Engel, N., van den Daele, K., Kolukisaoglu, U., Morgenthal, K., Weckwerth, W., Pärnik, T., Keerberg, O., and, Bauwe, H., (2007) Deletion of glycine decarboxylase in Arabidopsis is lethal under nonphotorespiratory conditions. Plant Physiol. 144, 1328-1335. (Pubitemid 47037448)
23. Ewald, R., Kolukisaoglu, U., Bauwe, U., Mikkat, S., and, Bauwe, H., (2007) Mitochondrial protein lipoylation does not exclusively depend on the mtKAS pathway of de novo fatty acid synthesis in Arabidopsis. Plant Physiol. 145, 41-48. (Pubitemid 47416475)
24. 2 enrichment of plants grown in pots and in hydroponic culture. Planta, 202, 510-521. (Pubitemid 27324645)
25. Ferro, M., Salvi, D., Riviere-Rolland, H., Vermat, T., Seigneurin-Berny, D., Grunwald, D., Garin, J., Joyard, J., and, Rolland, N., (2002) Integral membrane proteins of the chloroplast envelope: identification and subcellular localization of new transporters. Proc. Natl Acad. Sci. USA, 99, 11487-11492. (Pubitemid 34924952)
26. Fletcher, J.C., (2002) Shoot and floral meristem maintenance in Arabidopsis. Annu. Rev. Plant Biol. 53, 45-66. (Pubitemid 36257487)
27. Graham, I.A., (2008) Seed storage oil mobilization. Annu. Rev. Plant Biol. 59, 115-142. (Pubitemid 351813026)
28. Hayashi, M., Toriyama, K., Kondo, M., and, Nishimura, M., (1998) 2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid β-oxidation. Plant Cell, 10, 183-195.
29. Hilson, P., Allemeersch, J., Altmann, T., et al,. (2004) Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. Genome Res. 14, 2176-2218.
30. Igarashi, D., Miwa, T., Seki, M., Kobayashi, M., Kato, T., Tabata, S., Shinozaki, K., and, Ohsumi, C., (2003) Identification of photorespiratory glutamate:glyoxylate aminotransferase (GGAT) gene in Arabidopsis. Plant J. 33, 975-987. (Pubitemid 36400280)
31. Jiang, W., and, Yu, D., (2009) Arabidopsis WRKY2 transcription factor mediates seed germination and postgermination arrest of development by abscisic acid. BMC Plant Biol. 9, 96.
32. Joshi, V., Laubengayer, K.M., Schauer, N., Fernie, A.R., and, Jander, G., (2006) Two Arabidopsis threonine aldolases are nonredundant and compete with threonine deaminase for a common substrate pool. Plant Cell, 18, 3564-3575.
33. Keech, O., Dizengremel, P., and, Gardestrom, P., (2005) Preparation of leaf mitochondria from Arabidopsis thaliana. Physiol. Plant. 124, 403-409. (Pubitemid 41080331)
34. Kelly, G.J., and, Latzko, E., (1976) Inhibition of spinach-leaf phosphofructokinase by 2-phosphoglycollate. FEBS Lett. 68, 55-58.
35. Keys, A.J., (2006) The re-assimilation of ammonia produced by photorespiration and the nitrogen economy of C3 higher plants. Photosynth. Res. 87, 165-175.
36. Kinoshita, H., Nagasaki, J., Yoshikawa, N., Yamamoto, A., Takito, S., Kawasaki, M., Sugiyama, T., Miyake, H., Weber, A.P., and, Taniguchi, M., (2011) The chloroplastic 2-oxoglutarate/malate transporter has dual function as the malate valve and in carbon/nitrogen metabolism. Plant J. 65, 15-26.
37. Kirch, T., Simon, R., Grünewald, M., and, Werr, W., (2003) The DORNRÖSCHEN/ENHANCER OF SHOOT REGENERATION1 gene of Arabidopsis acts in the control of meristem cell fate and lateral organ development. Plant Cell, 15, 694-705. (Pubitemid 36339582)
38. Lawand, S., Dorne, A.J., Long, D., Coupland, G., Mache, R., and, Carol, P., (2002) Arabidopsis A BOUT DE SOUFFLE, which is homologous with mammalian carnitine acyl carrier, is required for postembryonic growth in the light. Plant Cell, 14, 2161-2173.
39. Leon, P., Arroyo, A., and, Mackenzie, S., (1998) Nuclear control of plastid and mitochondrial development in higher plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 49, 453-480.
40. Leroch, M., Neuhaus, H.E., Kirchberger, S., Zimmermann, S., Melzer, M., Gerhold, J., and, Tjaden, J., (2008) Identification of a novel adenine nucleotide transporter in the endoplasmic reticulum of Arabidopsis. Plant Cell, 20, 438-451. (Pubitemid 352844023)
41. Li, Y., Rosso, M.G., Strizhov, N., Viehoever, P., and, Weisshaar, B., (2003) GABI-Kat SimpleSearch: a flanking sequence tag (FST) database for the identification of T-DNA insertion mutants in Arabidopsis thaliana. Bioinformatics, 19, 1441-1442. (Pubitemid 36939826)
42. Liepman, A.H., and, Olsen, L.J., (2001) Peroxisomal alanine:glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana. Plant J. 25, 487-498. (Pubitemid 32442248)
43. Linka, N., Theodoulou, F.L., Haslam, R.P., Linka, M., Napier, J.A., Neuhaus, H.E., and, Weber, A.P., (2008) Peroxisomal ATP import is essential for seedling development in Arabidopsis thaliana. Plant Cell, 20, 3241-3257.
44. Long, J.A., Moan, E.I., Medford, J.I., and, Barton, M.K., (1996) A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis. Nature, 379, 66-69. (Pubitemid 26008135)
45. Lopez-Molina, L., Mongrand, S., and, Chua, N.H., (2001) A postgermination developmental arrest checkpoint is mediated by abscisic acid and requires the ABI5 transcription factor in Arabidopsis. Proc. Natl Acad. Sci. USA, 98, 4782-4787. (Pubitemid 32295053)
46. Lopez-Molina, L., Mongrand, S., McLachlin, D.T., Chait, B.T., and, Chua, N.H., (2002) ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination. Plant J. 32, 317-328. (Pubitemid 35307266)
47. Lurin, C., Andrés, C., Aubourg, S., et al,. (2004) Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis. Plant Cell, 16, 2089-2103. (Pubitemid 39059730)
48. Martin, T., Oswald, O., and, Graham, I.A., (2002) Arabidopsis seedling growth, storage lipid mobilization, and photosynthetic gene expression are regulated by carbon:nitrogen availability. Plant Physiol. 128, 472-481. (Pubitemid 34190862)
49. Murray, A.J., Blackwell, R.D., and, Lea, P.J., (1989) Metabolism of hydroxypyruvate in a mutant of barley lacking NADH-dependent hydroxypyruvate reductase, an important photorespiratory enzyme activity. Plant Physiol. 91, 395-400.
50. Obayashi, T., and, Kinoshita, K., (2010) Coexpression landscape in ATTED-II: usage of gene list and gene network for various types of pathways. J. Plant. Res. 123, 311-319.
51. Obayashi, T., Kinoshita, K., Nakai, K., Shibaoka, M., Hayashi, S., Saeki, M., Shibata, D., Saito, K., and, Ohta, H., (2007) ATTED-II: a database of co-expressed genes and cis elements for identifying co-regulated gene groups in Arabidopsis. Nucleic Acids Res. 35, D863-D869. (Pubitemid 46056323)
52. Ogren, W.L., (1984) Photorespiration: pathways, regulation, and modification. Annu. Rev. Plant Physiol. 35, 415-442.
53. Palmieri, F., and, Pierri, C.L., (2010) Mitochondrial metabolite transport. Essays Biochem. 47, 37-52.
54. Palmieri, F., Agrimi, G., Blanco, E., et al. (2006) Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins. Biochim. Biophys. Acta 1757, 1249-1262. (Pubitemid 44442126)
55. Palmieri, F., Pierri, C.L., De Grassi, A., Nunes-Nesi, A., and, Fernie, A.R., (2011) Evolution, structure and function of mitochondrial carriers: a review with new insights. Plant J. 66, 161-181.
56. Picault, N., Hodges, M., Palmieri, L., and, Palmieri, F., (2004) The growing family of mitochondrial carriers in Arabidopsis. Trends Plant Sci. 9, 138-146. (Pubitemid 38300260)
57. Pinfield-Wells, H., Rylott, E.L., Gilday, A.D., Graham, S., Job, K., Larson, T.R., and, Graham, I.A., (2005) Sucrose rescues seedling establishment but not germination of Arabidopsis mutants disrupted in peroxisomal fatty acid catabolism. Plant J. 43, 861-872.
58. Pogson, B.J., and, Albrecht, V., (2011) Genetic dissection of chloroplast biogenesis and development: an overview. Plant Physiol. 155, 1545-1551.
59. Rebeille, F., Alban, C., Bourguignon, J., Ravanel, S., and, Douce, R., (2007) The role of plant mitochondria in the biosynthesis of coenzymes. Photosynth. Res. 92, 149-162. (Pubitemid 47222258)
60. Renné, P., Dressen, U., Hebbeker, U., Hille, D., Flügge, U.I., Westhoff, P., and, Weber, A.P., (2003) The Arabidopsis mutant dct is deficient in the plastidic glutamate/malate translocator DiT2. Plant J. 35, 316-331. (Pubitemid 36990635)
61. Reumann, S., and, Weber, A.P., (2006) Plant peroxisomes respire in the light: some gaps of the photorespiratory C2 cycle have become filled-others remain. Biochim. Biophys. Acta 1763, 1496-1510. (Pubitemid 44880482)
62. Rieder, B., and, Neuhaus, H.E., (2011) Identification of an Arabidopsis plasma membrane-located ATP transporter important for anther development. Plant Cell, 23, 1932-1944.
63. Riou-Khamlichi, C., Menges, M., Healy, J.M., and, Murray, J.A., (2000) Sugar control of the plant cell cycle: differential regulation of Arabidopsis D-type cyclin gene expression. Mol. Cell. Biol. 20, 4513-4521. (Pubitemid 30396099)
64. Rosar, C., Kanonenberg, K., Nanda, A.M., Mielewczik, M., Bräutigam, A., Nowák, O., Strnad, M., Walter, A., and, Weber, A.P.M., (2012) The leaf reticulate mutant dov1 is impaired in the first step of purine metabolism. Mol. Plant, 5, 1227-1241.
65. Rosso, M.G., Li, Y., Strizhov, N., Reiss, B., Dekker, K., and, Weisshaar, B., (2003) An Arabidopsis thaliana T-DNA mutagenized population (GABI-Kat) for flanking sequence tag-based reverse genetics. Plant Mol. Biol. 53, 247-259. (Pubitemid 38105653)
66. Ruepp, A., Zollner, A., Maier, D., et al,. (2004) The FunCat, a functional annotation scheme for systematic classification of proteins from whole genomes. Nucleic Acids Res. 32, 5539-5545. (Pubitemid 39545671)
67. Schwarte, S., and, Bauwe, H., (2007) Identification of the photorespiratory 2-phosphoglycolate phosphatase, PGLP1, in Arabidopsis. Plant Physiol. 144, 1580-1586. (Pubitemid 47037450)
68. Shelp, B.J., Mullen, R.T., and, Waller, J.C., (2012) Compartmentation of GABA metabolism raises intriguing questions. Trends Plant Sci. 17, 57-59.
69. Somerville, C.R., (2001) An early Arabidopsis demonstration. Resolving a few issues concerning photorespiration. Plant Physiol. 125, 20-24. (Pubitemid 32116717)
70. Somerville, C.R., and, Ogren, W.L., (1979) A phosphoglycolate phosphatase-deficient mutant of Arabidopsis. Nature, 280, 833-836.
71. Somerville, C.R., and, Ogren, W.L., (1981) Photorespiration-deficient mutants of Arabidopsis thaliana lacking mitochondrial serine transhydroxymethylase activity. Plant Physiol. 67, 666-671.
72. Somerville, S.C., and, Ogren, W.L., (1983) An Arabidopsis thaliana mutant defective in chloroplast dicarboxylate transport. Proc. Natl Acad. Sci. USA, 80, 1290-1294.
73. Timm, S., Nunes-Nesi, A., Pärnik, T., Morgenthal, K., Wienkoop, S., Keerberg, O., Weckwerth, W., Kleczkowski, L.A., Fernie, A.R., and, Bauwe, H., (2008) A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis. Plant Cell, 20, 2848-2859. (Pubitemid 352844594)
74. 2 acclimation analysis reveals plasticity of the photorespiratory pathway and indicates regulatory links to cellular metabolism of Arabidopsis. PLoS ONE, 7, e42809.
75. Toka, I., Planchais, S., Cabassa, C., Justin, A.M., De Vos, D., Richard, L., Savouré, A., and, Carol, P., (2010) Mutations in the hyperosmotic stress-responsive mitochondrial BASIC AMINO ACID CARRIER2 enhance proline accumulation in Arabidopsis. Plant Physiol. 152, 1851-1862.
76. Tolbert, N.E., (1997) The C2 oxidative photosynthetic carbon cycle. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 1-25.
77. Tsuchiya, T., Ohta, H., Okawa, K., Iwamatsu, A., Shimada, H., Masuda, T., and, Takamiya, K., (1999) Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate. Proc. Natl Acad. Sci. USA, 96, 15362-15367. (Pubitemid 30019816)
78. Usadel, B., Nagel, A., Thimm, O., et al. (2005) Extension of the visualization tool MapMan to allow statistical analysis of arrays, display of corresponding genes, and comparison with known responses. Plant Physiol, 138, 1195-1204. (Pubitemid 43142069)
79. Voll, L.M., Jamai, A., Renné, P., Voll, H., McClung, C.R., and, Weber, A.P.M., (2006) The photorespiratory Arabidopsis shm1 mutant is deficient in SHM1. Plant Physiol. 140, 59-66. (Pubitemid 43956302)
80. Volokita, M., and, Somerville, C.R., (1987) The primary structure of spinach glycolate oxidase deduced from the DNA sequence of a cDNA clone. J. Biol. Chem. 262, 15825-15828.
81. Wada, H., Shintani, D., and, Ohlrogge, J., (1997) Why do mitochondria synthesize fatty acids? Evidence for involvement in lipoic acid production. Proc. Natl Acad. Sci. USA, 94, 1591-1596. (Pubitemid 27087896)
82. Walker, J.L., and, Oliver, D.J., (1986) Glycine decarboxylase multienzyme complex. Purification and partial characterization from pea leaf mitochondria. J. Biol. Chem. 261, 2214-2221.
83. Wallsgrove, R.M., Turner, J.C., Hall, N.P., Kendall, A.C., and, Bright, S.W., (1987) Barley mutants lacking chloroplast glutamine synthetase-biochemical and genetic analysis. Plant Physiol. 83, 155-158.
84. Weigel, D., and, Jürgens, G., (2002) Stem cells that make stems. Nature, 415, 751-754. (Pubitemid 34150488)
85. Yu, C., Claybrook, D.L., and, Huang, A.H.C., (1983) Transport of glycine, serine, and proline into spinach leaf mitochondria. Arch. Biochem. Biophys. 227, 180-187.