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Volumn 33, Issue 6, 2012, Pages 1216-1223

Nandrolone, an anabolic steroid, stabilizes numb protein through inhibition of mdm2 in C2C12 myoblasts

Author keywords

Androgen receptor; Notch signaling; Skeleton muscle

Indexed keywords

NANDROLONE; NOTCH RECEPTOR; PROTEIN; PROTEIN MDM2; PROTEIN NUMB; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84874425806     PISSN: 01963635     EISSN: 19394640     Source Type: Journal    
DOI: 10.2164/jandrol.112.016428     Document Type: Article
Times cited : (13)

References (29)
  • 1
    • 0033520806 scopus 로고    scopus 로고
    • Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence
    • Agus DB, Cordon-Cardo C, Fox W, Drobnjak M, Koff A, Golde DW, Scher HI. Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence. J Natl Cancer Inst. 1999;91:1869-1876.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1869-1876
    • Agus, D.B.1    Cordon-Cardo, C.2    Fox, W.3    Drobnjak, M.4    Koff, A.5    Golde, D.W.6    Scher, H.I.7
  • 3
    • 0034659374 scopus 로고    scopus 로고
    • a member of the immunoglobulin superfamily that is essential for myoblast fusion
    • Bour BA, Chakravarti M, West JM, Abmayr SM. Drosophila SNS, a member of the immunoglobulin superfamily that is essential for myoblast fusion. Genes Dev. 2000;14:1498-1511.
    • (2000) Genes Dev , vol.14 , pp. 1498-1511
    • Bour, B.A.1    Chakravarti, M.2    West, J.M.3    Abmayr, S.M.4    Drosophila, S.N.S.5
  • 4
    • 37549039009 scopus 로고    scopus 로고
    • A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis
    • Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA. A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell. 2008;2:50-59.
    • (2008) Cell Stem Cell , vol.2 , pp. 50-59
    • Brack, A.S.1    Conboy, I.M.2    Conboy, M.J.3    Shen, J.4    Rando, T.A.5
  • 5
    • 48949118769 scopus 로고    scopus 로고
    • A role of Numb in p53 stabilization
    • Carter S, Vousden KH. A role of Numb in p53 stabilization. Genome Biol. 2008;9:221.1-221.3.
    • (2008) Genome Biol , vol.9
    • Carter, S.1    Vousden, K.H.2
  • 6
    • 0036744815 scopus 로고    scopus 로고
    • The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis
    • Conboy IM, Rando TA. The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev Cell. 2002;3:397-409.
    • (2002) Dev Cell , vol.3 , pp. 397-409
    • Conboy, I.M.1    Rando, T.A.2
  • 7
    • 33748298775 scopus 로고    scopus 로고
    • Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: structural determinants of numb association with the cortical membrane
    • Dho SE, Trejo J, Siderovski DP, McGlade CJ. Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: structural determinants of numb association with the cortical membrane. Mol Biol Cell. 2006;17:4142-4155.
    • (2006) Mol Biol Cell , vol.17 , pp. 4142-4155
    • Dho, S.E.1    Trejo, J.2    Siderovski, D.P.3    McGlade, C.J.4
  • 14
    • 44349157577 scopus 로고    scopus 로고
    • Pharmacology of anabolic steroids
    • Kicman AT. Pharmacology of anabolic steroids. Br J Pharmacol. 2008;154:502-521.
    • (2008) Br J Pharmacol , vol.154 , pp. 502-521
    • Kicman, A.T.1
  • 16
    • 2342500360 scopus 로고    scopus 로고
    • The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
    • Lu L, Schulz H, Wolf DA. The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells. BMC Cell Biol. 2002;3:22.
    • (2002) BMC Cell Biol , vol.3 , pp. 22
    • Lu, L.1    Schulz, H.2    Wolf, D.A.3
  • 17
    • 24344443668 scopus 로고    scopus 로고
    • The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis
    • Luo D, Renault VM, Rando TA. The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin Cell Dev Biol. 2005;16:612-622.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 612-622
    • Luo, D.1    Renault, V.M.2    Rando, T.A.3
  • 18
    • 0037080811 scopus 로고    scopus 로고
    • LNX functions as a ring type E3 ubiqutin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation
    • Nie J, McGill MA, Dermer M, Dho SE, Wolting CD, McGlade CJ. LNX functions as a ring type E3 ubiqutin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation. EMBO J. 2002;21:93-102.
    • (2002) EMBO J , vol.21 , pp. 93-102
    • Nie, J.1    McGill, M.A.2    Dermer, M.3    Dho, S.E.4    Wolting, C.D.5    McGlade, C.J.6
  • 19
    • 34250820373 scopus 로고    scopus 로고
    • Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3
    • Nishimura T, Kaibuchi K. Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev Cell. 2007;13:15-28.
    • (2007) Dev Cell , vol.13 , pp. 15-28
    • Nishimura, T.1    Kaibuchi, K.2
  • 20
    • 0032915458 scopus 로고    scopus 로고
    • Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
    • Nofziger D, Miyamoto A, Lyons KM, Weinmaster G. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development. 1999;126:1689-1702.
    • (1999) Development , vol.126 , pp. 1689-1702
    • Nofziger, D.1    Miyamoto, A.2    Lyons, K.M.3    Weinmaster, G.4
  • 21
    • 49049083353 scopus 로고    scopus 로고
    • Signaling in muscle atrophy and hypertrophy
    • Sandri M. Signaling in muscle atrophy and hypertrophy. Physiology. 2008;23:160-170.
    • (2008) Physiology , vol.23 , pp. 160-170
    • Sandri, M.1
  • 22
    • 0242468434 scopus 로고    scopus 로고
    • Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H-10T1/2 pluripotent cells through an androgen receptor-mediated pathway
    • Singh R, Artaza JN, Taylor WE, Gonzalez-Cadavid NF, Bhasin S. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H-10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology. 2003;144:5081-5088.
    • (2003) Endocrinology , vol.144 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzalez-Cadavid, N.F.4    Bhasin, S.5
  • 23
    • 0032728593 scopus 로고    scopus 로고
    • Anabolic-androgenic steroid administration causes hypertrophy of immobilized and nonimmobilized skeletal muscle in a sedentary rabbit model
    • Taylor DC, Brooks DE, Ryan JB. Anabolic-androgenic steroid administration causes hypertrophy of immobilized and nonimmobilized skeletal muscle in a sedentary rabbit model. Am J Sports Med. 1999;27:718-727.
    • (1999) Am J Sports Med , vol.27 , pp. 718-727
    • Taylor, D.C.1    Brooks, D.E.2    Ryan, J.B.3
  • 24
    • 69249209681 scopus 로고    scopus 로고
    • Numb regulates cell-cell adhesion and polarity in response to tyrosin kinase signaling
    • Wang Z, Sandiford S, Wu C, Li SS. Numb regulates cell-cell adhesion and polarity in response to tyrosin kinase signaling. EMBO J. 2009;28:2360-2373.
    • (2009) EMBO J , vol.28 , pp. 2360-2373
    • Wang, Z.1    Sandiford, S.2    Wu, C.3    Li, S.S.4
  • 27
    • 55049103095 scopus 로고    scopus 로고
    • All muscle satellite cells are equal, but are some more equal than others?
    • Zammit PS. All muscle satellite cells are equal, but are some more equal than others? J Cell Sci. 2008;121:2975-2982.
    • (2008) J Cell Sci , vol.121 , pp. 2975-2982
    • Zammit, P.S.1
  • 28
    • 37749030886 scopus 로고    scopus 로고
    • Effects of nandrolone on denervation atrophy depend upon time after nerve transection
    • ZhaoJ, ZhangY, ZhaoW, WuY, PanJ, BaumanWA, CardozoC. Effects of nandrolone on denervation atrophy depend upon time after nerve transection. Muscle Nerve. 2008;37:42-49.
    • (2008) Muscle Nerve , vol.37 , pp. 42-49
    • Zhao, J.1    Zhang, Y.2    Zhao, W.3    Wu, Y.4    Pan, J.5    Bauman, W.A.6    Cardozo, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.