메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages

ABCD2 Is a Direct Target of β-Catenin and TCF-4: Implications for X-Linked Adrenoleukodystrophy Therapy

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER SUBFAMILY D MEMBER 2 PROTEIN; BETA CATENIN; T CELL FACTOR PROTEIN; T CELL FACTOR PROTEIN 4; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID;

EID: 84874325516     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056242     Document Type: Article
Times cited : (13)

References (45)
  • 1
    • 0027532282 scopus 로고
    • Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters
    • Mosser J, Douar AM, Sarde CO, Kioschis P, Feil R, et al. (1993) Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters. Nature 361: 726-730.
    • (1993) Nature , vol.361 , pp. 726-730
    • Mosser, J.1    Douar, A.M.2    Sarde, C.O.3    Kioschis, P.4    Feil, R.5
  • 2
    • 0035208916 scopus 로고    scopus 로고
    • ABCD1 mutations and the X-linked adrenoleukodystrophy mutation database: role in diagnosis and clinical correlations
    • Kemp S, Pujol A, Waterham HR, van Geel BM, Boehm CD, et al. (2001) ABCD1 mutations and the X-linked adrenoleukodystrophy mutation database: role in diagnosis and clinical correlations. Hum Mutat 18: 499-515.
    • (2001) Hum Mutat , vol.18 , pp. 499-515
    • Kemp, S.1    Pujol, A.2    Waterham, H.R.3    van Geel, B.M.4    Boehm, C.D.5
  • 4
    • 77953191945 scopus 로고    scopus 로고
    • Pathomechanisms underlying X-adrenoleukodystrophy: a three-hit hypothesis
    • Singh I, Pujol A, (2010) Pathomechanisms underlying X-adrenoleukodystrophy: a three-hit hypothesis. Brain Pathol 20: 838-844.
    • (2010) Brain Pathol , vol.20 , pp. 838-844
    • Singh, I.1    Pujol, A.2
  • 5
    • 70449427834 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
    • Cartier N, Hacein-Bey-Abina S, Bartholomae CC, Veres G, Schmidt M, et al. (2009) Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 326: 818-823.
    • (2009) Science , vol.326 , pp. 818-823
    • Cartier, N.1    Hacein-Bey-Abina, S.2    Bartholomae, C.C.3    Veres, G.4    Schmidt, M.5
  • 6
    • 57349105177 scopus 로고    scopus 로고
    • The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters
    • van Roermund CW, Visser WF, Ijlst L, van Cruchten A, Boek M, et al. (2008) The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters. FASEB J 22: 4201-4208.
    • (2008) FASEB J , vol.22 , pp. 4201-4208
    • van Roermund, C.W.1    Visser, W.F.2    Ijlst, L.3    van Cruchten, A.4    Boek, M.5
  • 7
    • 77953228906 scopus 로고    scopus 로고
    • Biochemical aspects of X-linked adrenoleukodystrophy
    • Kemp S, Wanders R, (2010) Biochemical aspects of X-linked adrenoleukodystrophy. Brain Pathol 20: 831-837.
    • (2010) Brain Pathol , vol.20 , pp. 831-837
    • Kemp, S.1    Wanders, R.2
  • 8
    • 80052579389 scopus 로고    scopus 로고
    • Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients
    • Jang J, Kang HC, Kim HS, Kim JY, Huh YJ, et al. (2011) Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients. Ann Neurol 70: 402-409.
    • (2011) Ann Neurol , vol.70 , pp. 402-409
    • Jang, J.1    Kang, H.C.2    Kim, H.S.3    Kim, J.Y.4    Huh, Y.J.5
  • 9
    • 0031561433 scopus 로고    scopus 로고
    • cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter
    • Holzinger A, Kammerer S, Berger J, Roscher AA, (1997) cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter. Biochem Biophys Res Commun 239: 261-264.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 261-264
    • Holzinger, A.1    Kammerer, S.2    Berger, J.3    Roscher, A.A.4
  • 10
    • 0031730433 scopus 로고    scopus 로고
    • Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy
    • Kemp S, Wei HM, Lu JF, Braiterman LT, McGuinness MC, et al. (1998) Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy. Nat Med 4: 1261-1268.
    • (1998) Nat Med , vol.4 , pp. 1261-1268
    • Kemp, S.1    Wei, H.M.2    Lu, J.F.3    Braiterman, L.T.4    McGuinness, M.C.5
  • 11
    • 0032898425 scopus 로고    scopus 로고
    • Retroviral-mediated adrenoleukodystrophy-related gene transfer corrects very long chain fatty acid metabolism in adrenoleukodystrophy fibroblasts: implications for therapy
    • Flavigny E, Sanhaj A, Aubourg P, Cartier N, (1999) Retroviral-mediated adrenoleukodystrophy-related gene transfer corrects very long chain fatty acid metabolism in adrenoleukodystrophy fibroblasts: implications for therapy. FEBS Lett 448: 261-264.
    • (1999) FEBS Lett , vol.448 , pp. 261-264
    • Flavigny, E.1    Sanhaj, A.2    Aubourg, P.3    Cartier, N.4
  • 12
    • 0032924991 scopus 로고    scopus 로고
    • Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy
    • Netik A, Forss-Petter S, Holzinger A, Molzer B, Unterrainer G, et al. (1999) Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy. Hum Mol Genet 8: 907-913.
    • (1999) Hum Mol Genet , vol.8 , pp. 907-913
    • Netik, A.1    Forss-Petter, S.2    Holzinger, A.3    Molzer, B.4    Unterrainer, G.5
  • 13
    • 9744221106 scopus 로고    scopus 로고
    • Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy
    • Pujol A, Ferrer I, Camps C, Metzger E, Hindelang C, et al. (2004) Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy. Hum Mol Genet 13: 2997-3006.
    • (2004) Hum Mol Genet , vol.13 , pp. 2997-3006
    • Pujol, A.1    Ferrer, I.2    Camps, C.3    Metzger, E.4    Hindelang, C.5
  • 14
    • 0032562653 scopus 로고    scopus 로고
    • Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy
    • Singh I, Pahan K, Khan M, (1998) Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. FEBS Lett 426: 342-346.
    • (1998) FEBS Lett , vol.426 , pp. 342-346
    • Singh, I.1    Pahan, K.2    Khan, M.3
  • 15
    • 80054100418 scopus 로고    scopus 로고
    • HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes
    • Singh J, Khan M, Singh I, (2011) HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes. J Lipid Res 52: 2056-2069.
    • (2011) J Lipid Res , vol.52 , pp. 2056-2069
    • Singh, J.1    Khan, M.2    Singh, I.3
  • 16
    • 79953326378 scopus 로고    scopus 로고
    • ABC subfamily D proteins and very long chain fatty acid metabolism as novel targets in adrenoleukodystrophy
    • Morita M, Shimozawa N, Kashiwayama Y, Suzuki Y, Imanaka T, (2011) ABC subfamily D proteins and very long chain fatty acid metabolism as novel targets in adrenoleukodystrophy. Curr Drug Targets 12: 694-706.
    • (2011) Curr Drug Targets , vol.12 , pp. 694-706
    • Morita, M.1    Shimozawa, N.2    Kashiwayama, Y.3    Suzuki, Y.4    Imanaka, T.5
  • 17
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through beta-catenin
    • Moon RT, Bowerman B, Boutros M, Perrimon N, (2002) The promise and perils of Wnt signaling through beta-catenin. Science 296: 1644-1646.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 18
    • 1142298447 scopus 로고    scopus 로고
    • Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells
    • Lee HY, Kleber M, Hari L, Brault V, Suter U, et al. (2004) Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science 303: 1020-1023.
    • (2004) Science , vol.303 , pp. 1020-1023
    • Lee, H.Y.1    Kleber, M.2    Hari, L.3    Brault, V.4    Suter, U.5
  • 19
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • Nusse R, (2005) Wnt signaling in disease and in development. Cell Res 15: 28-32.
    • (2005) Cell Res , vol.15 , pp. 28-32
    • Nusse, R.1
  • 20
    • 58049203043 scopus 로고    scopus 로고
    • Wnt-related molecules and signaling pathway equilibrium in hematopoiesis
    • Malhotra S, Kincade PW, (2009) Wnt-related molecules and signaling pathway equilibrium in hematopoiesis. Cell Stem Cell 4: 27-36.
    • (2009) Cell Stem Cell , vol.4 , pp. 27-36
    • Malhotra, S.1    Kincade, P.W.2
  • 22
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H, (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 23
    • 77149174855 scopus 로고    scopus 로고
    • Wnt signaling from development to disease: insights from model systems
    • Cadigan KM, Peifer M, (2009) Wnt signaling from development to disease: insights from model systems. Cold Spring Harb Perspect Biol 1: a002881.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Cadigan, K.M.1    Peifer, M.2
  • 24
    • 33845355511 scopus 로고    scopus 로고
    • Diversity of LEF/TCF action in development and disease
    • Arce L, Yokoyama NN, Waterman ML, (2006) Diversity of LEF/TCF action in development and disease. Oncogene 25: 7492-7504.
    • (2006) Oncogene , vol.25 , pp. 7492-7504
    • Arce, L.1    Yokoyama, N.N.2    Waterman, M.L.3
  • 25
    • 0037109002 scopus 로고    scopus 로고
    • Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy
    • Weinhofer I, Forss-Petter S, Zigman M, Berger J, (2002) Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy. Hum Mol Genet 11: 2701-2708.
    • (2002) Hum Mol Genet , vol.11 , pp. 2701-2708
    • Weinhofer, I.1    Forss-Petter, S.2    Zigman, M.3    Berger, J.4
  • 26
    • 29244469095 scopus 로고    scopus 로고
    • Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation
    • Weinhofer I, Kunze M, Rampler H, Bookout AL, Forss-Petter S, et al. (2005) Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. J Biol Chem 280: 41243-41251.
    • (2005) J Biol Chem , vol.280 , pp. 41243-41251
    • Weinhofer, I.1    Kunze, M.2    Rampler, H.3    Bookout, A.L.4    Forss-Petter, S.5
  • 27
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
    • Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, et al. (1997) Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 275: 1784-1787.
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3    van Wichen, D.4    de Weger, R.5
  • 28
    • 77949587674 scopus 로고    scopus 로고
    • Lentiviral vectors to probe and manipulate the Wnt signaling pathway
    • Fuerer C, Nusse R, (2010) Lentiviral vectors to probe and manipulate the Wnt signaling pathway. PLoS One 5: e9370.
    • (2010) PLoS One , vol.5
    • Fuerer, C.1    Nusse, R.2
  • 29
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR, (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77: 51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 30
    • 37249048769 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator
    • Pulukuri SM, Gorantla B, Rao JS, (2007) Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. J Biol Chem 282: 35594-35603.
    • (2007) J Biol Chem , vol.282 , pp. 35594-35603
    • Pulukuri, S.M.1    Gorantla, B.2    Rao, J.S.3
  • 31
    • 66149149803 scopus 로고    scopus 로고
    • Hepatitis C virus nonstructural 4B protein modulates sterol regulatory element-binding protein signaling via the AKT pathway
    • Park CY, Jun HJ, Wakita T, Cheong JH, Hwang SB, (2009) Hepatitis C virus nonstructural 4B protein modulates sterol regulatory element-binding protein signaling via the AKT pathway. J Biol Chem 284: 9237-9246.
    • (2009) J Biol Chem , vol.284 , pp. 9237-9246
    • Park, C.Y.1    Jun, H.J.2    Wakita, T.3    Cheong, J.H.4    Hwang, S.B.5
  • 32
    • 0035949194 scopus 로고    scopus 로고
    • Diagnostic patterns of very-long-chain fatty acids in plasma of patients with X-linked adrenoleukodystrophy
    • Paik MJ, Kim KR, Yoon HR, Kim HJ, (2001) Diagnostic patterns of very-long-chain fatty acids in plasma of patients with X-linked adrenoleukodystrophy. J Chromatogr B Biomed Sci Appl 760: 149-157.
    • (2001) J Chromatogr B Biomed Sci Appl , vol.760 , pp. 149-157
    • Paik, M.J.1    Kim, K.R.2    Yoon, H.R.3    Kim, H.J.4
  • 33
    • 0018973786 scopus 로고
    • Adrenoleukodystrophy: elevated C26 fatty acid in cultured skin fibroblasts
    • Moser HW, Moser AB, Kawamura N, Murphy J, Suzuki K, et al. (1980) Adrenoleukodystrophy: elevated C26 fatty acid in cultured skin fibroblasts. Ann Neurol 7: 542-549.
    • (1980) Ann Neurol , vol.7 , pp. 542-549
    • Moser, H.W.1    Moser, A.B.2    Kawamura, N.3    Murphy, J.4    Suzuki, K.5
  • 34
    • 0345006147 scopus 로고    scopus 로고
    • Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
    • de La Coste A, Romagnolo B, Billuart P, Renard CA, Buendia MA, et al. (1998) Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci U S A 95: 8847-8851.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8847-8851
    • de la Coste, A.1    Romagnolo, B.2    Billuart, P.3    Renard, C.A.4    Buendia, M.A.5
  • 35
    • 0032932397 scopus 로고    scopus 로고
    • Plasma very long chain fatty acids in 3,000 peroxisome disease patients and 29,000 controls
    • Moser AB, Kreiter N, Bezman L, Lu S, Raymond GV, et al. (1999) Plasma very long chain fatty acids in 3,000 peroxisome disease patients and 29,000 controls. Ann Neurol 45: 100-110.
    • (1999) Ann Neurol , vol.45 , pp. 100-110
    • Moser, A.B.1    Kreiter, N.2    Bezman, L.3    Lu, S.4    Raymond, G.V.5
  • 36
    • 0027186364 scopus 로고
    • A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy
    • Aubourg P, Adamsbaum C, Lavallard-Rousseau MC, Rocchiccioli F, Cartier N, et al. (1993) A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy. N Engl J Med 329: 745-752.
    • (1993) N Engl J Med , vol.329 , pp. 745-752
    • Aubourg, P.1    Adamsbaum, C.2    Lavallard-Rousseau, M.C.3    Rocchiccioli, F.4    Cartier, N.5
  • 37
    • 0032480227 scopus 로고    scopus 로고
    • Lovastatin for X-linked adrenoleukodystrophy
    • Singh I, Khan M, Key L, Pai S, (1998) Lovastatin for X-linked adrenoleukodystrophy. N Engl J Med 339: 702-703.
    • (1998) N Engl J Med , vol.339 , pp. 702-703
    • Singh, I.1    Khan, M.2    Key, L.3    Pai, S.4
  • 38
    • 0343239065 scopus 로고    scopus 로고
    • Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients
    • Pai GS, Khan M, Barbosa E, Key LL, Craver JR, et al. (2000) Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients. Mol Genet Metab 69: 312-322.
    • (2000) Mol Genet Metab , vol.69 , pp. 312-322
    • Pai, G.S.1    Khan, M.2    Barbosa, E.3    Key, L.L.4    Craver, J.R.5
  • 40
    • 0034819367 scopus 로고    scopus 로고
    • Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha
    • Fourcade S, Savary S, Albet S, Gauthe D, Gondcaille C, et al. (2001) Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha. Eur J Biochem 268: 3490-3500.
    • (2001) Eur J Biochem , vol.268 , pp. 3490-3500
    • Fourcade, S.1    Savary, S.2    Albet, S.3    Gauthe, D.4    Gondcaille, C.5
  • 41
    • 20244364534 scopus 로고    scopus 로고
    • Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator
    • Gondcaille C, Depreter M, Fourcade S, Lecca MR, Leclercq S, et al. (2005) Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator. J Cell Biol 169: 93-104.
    • (2005) J Cell Biol , vol.169 , pp. 93-104
    • Gondcaille, C.1    Depreter, M.2    Fourcade, S.3    Lecca, M.R.4    Leclercq, S.5
  • 42
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • He TC, Sparks AB, Rago C, Hermeking H, Zawel L, et al. (1998) Identification of c-MYC as a target of the APC pathway. Science 281: 1509-1512.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3    Hermeking, H.4    Zawel, L.5
  • 43
    • 2542546650 scopus 로고    scopus 로고
    • Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells
    • Cha MY, Kim CM, Park YM, Ryu WS, (2004) Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells. Hepatology 39: 1683-1693.
    • (2004) Hepatology , vol.39 , pp. 1683-1693
    • Cha, M.Y.1    Kim, C.M.2    Park, Y.M.3    Ryu, W.S.4
  • 44
    • 54149089828 scopus 로고    scopus 로고
    • Distinct modulatory roles for thyroid hormone receptors TRalpha and TRbeta in SREBP1-activated ABCD2 expression
    • Weinhofer I, Kunze M, Rampler H, Forss-Petter S, Samarut J, et al. (2008) Distinct modulatory roles for thyroid hormone receptors TRalpha and TRbeta in SREBP1-activated ABCD2 expression. Eur J Cell Biol 87: 933-945.
    • (2008) Eur J Cell Biol , vol.87 , pp. 933-945
    • Weinhofer, I.1    Kunze, M.2    Rampler, H.3    Forss-Petter, S.4    Samarut, J.5
  • 45
    • 0034672587 scopus 로고    scopus 로고
    • Characterization of the adrenoleukodystrophy-related (ALDR, ABCD2) gene promoter: inductibility by retinoic acid and forskolin
    • Pujol A, Troffer-Charlier N, Metzger E, Chimini G, Mandel JL, (2000) Characterization of the adrenoleukodystrophy-related (ALDR, ABCD2) gene promoter: inductibility by retinoic acid and forskolin. Genomics 70: 131-139.
    • (2000) Genomics , vol.70 , pp. 131-139
    • Pujol, A.1    Troffer-Charlier, N.2    Metzger, E.3    Chimini, G.4    Mandel, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.