Phenylbutyrate up-regulates the adrenoleukodystrophy-related as a nonclassical peroxisome proliferator

Journal of Cell Biology

Volumn 169, Issue 1, 2005, Pages 93-104

  Gondcaille, Catherine ^a   Depreter, Marianne ^b,e   Fourcade, Stéphane ^a   Lecca, Maria Rita ^a   Leclercq, Sabrina ^a   Martin, Pascal G P ^c   Pineau, Thierry ^c   Cadepond, Françoise ^d   Eletr, Martine ^d   Bertrand, Nathalie ^a   Beley, Alain ^a   Duclos, Sandrine ^a   De Craemer, Dirk ^b   Roels, Frank ^b   Savary, Stéphane ^a   Bugaut, Maurice ^a  

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b GHENT UNIVERSITY   (Belgium)

^c CEMAGREF   (France)

^d INSERM   (France)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; ABC TRANSPORTER; ARYLBUTYRIC ACID DERIVATIVE; HISTONE DEACETYLASE; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ADRENOLEUKODYSTROPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GENE; GENE MUTATION; GLIA CELL; LIVER; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RODENT; SEQUENCE HOMOLOGY; UPREGULATION; X CHROMOSOME LINKED DISORDER;

ADRENOLEUKODYSTROPHY; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; FIBROBLASTS; HEPATOCYTES; HISTONE DEACETYLASES; HUMANS; LIVER; NEUROGLIA; PEROXISOME PROLIFERATORS; PEROXISOMES; PHENYLBUTYRATES; PPAR ALPHA; PROMOTER REGIONS (GENETICS); RATS; RATS, WISTAR; UP-REGULATION;

RODENTIA;

EID: 20244364534     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200501036     Document Type: Article

References (52)

1. Abe, I., and Y. Fujiki. 1998. cDNA cloning and characterization of a constitutively expressed isoform of the human peroxin Pex11p. Biochem. Biophys. Res. Commun. 252:529-533.
2. Abe, I., K. Okumoto, S. Tamura, and Y. Fujiki. 1998. Clofibrate- inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11. FEBS Lett. 431:468-472.
3. Albet, S., C. Causeret, M. Bentejac, J.L. Mandel, P. Aubourg, and M. Bugaut. 1997. Fenofibrate differently alters expression of genes encoding ATP-binding transporter proteins of the peroxisomal membrane. FEBS Lett. 405:394-397.
4. Albet, S., M. Bentejac, S. Savary, C. Gondcaille, A. Netik, J. Berger, C. Szpirer, N. Troffer-Charlier, and M. Bugaut. 2001. Rat adrenoleukodystrophy- related (ALDR) gene: full-length cDNA sequence and new insight in expression. Biochim. Biophys. Acta. 1517:257-269.
5. Baumgart, E., A. Volkl, T. Hashimoto, and H.D. Fahimi. 1989. Biogenesis of peroxisomes: immunocytochemical investigation of peroxisomal membrane proteins in proliferating rat liver peroxisomes and in catalase-negative membrane loops. J. Cell Biol. 108:2221-2231.
6. Berger, J., S. Albet, M. Bentejac, A. Netik, A. Holzinger, A.A. Roscher, M. Bugaut, and S. Forss-Petter. 1999. The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental ex-pression. Eur. J. Biochem. 265:719-727.
7. Braiterman, L.T., S. Zheng, P.A. Watkins, M.T. Geraghty, G. Johnson, M.C. McGuinness, A.B. Moser, and K.D. Smith. 1998. Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins. Hum. Mol. Genet. 7:239-247.
8. Davie, J.R. 2003. Inhibition of histone deacetylase activity by butyrate. J. Nutr. 133:2485S-2493S.
9. Depreter, M., J. Vandesompele, M. Espeel, F. Speleman, and F. Roels. 2002. Modulation of the peroxisomal gene expression pattern by dehydroepiandrosterone and vitamin D: therapeutic implications. J. Endocrinol. 175:779-792.
10. Doetschman, T.C., H. Eistetter, M. Katz, W. Schmidt, and R. Kemler. 1985. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morphol. 87:27-45.
11. Doetzlhofer, A., H. Rotheneder, G. Lagger, M. Koranda, V. Kurtev, G. Brosch, E. Wintersberger, and C. Seiser. 1999. Histone deacetylase 1 can repress transcription by binding to Sp1. Mol. Cell. Biol. 19:5504-5511.
12. Duclos, S., J. Bride, L.C. Ramirez, and P. Bournot. 1997. Peroxisome proliferation and beta-oxidation in Fao and MH1C1 rat hepatoma cells, HepG2 human hepatoblastoma cells and cultured human hepatocytes: effect of ciprofibrate. Eur. J. Cell Biol. 72:314-323.
13. Espeel, M., and G. Van Limbergen. 1995. Immunocytochemical localization of peroxisomal proteins in human liver and kidney. J. Inherit. Metab. Dis. 18:135-154.
14. Flavigny, E., A. Sanhaj, P. Aubourg, and N. Cartier. 1999. Retroviral-mediated adrenoleukodystrophy-related gene transfer corrects very long chain fatty acid metabolism in adrenoleukodystrophy fibroblasts: implications for therapy. FEBS Lett. 448:261-264.
15. Fourcade, S., S. Savary, S. Albet, D. Gauthe, C. Gondcaille, T. Pineau, J. Bellenger, M. Bentejac, A. Holzinger, J. Berger, and M. Bugaut. 2001. Fi-brate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha. Eur. J. Biochem. 268:3490-3500.
16. Fourcade, S., S. Savary, C. Gondcaille, J. Berger, A. Netik, F. Cadepond, M. ElEtr, B. Molzer, and M. Bugaut. 2003. Thyroid hormone induction of the adrenoleukodystrophy-related gene (ABCD2). Mol. Pharmacol. 63:1296-1303.
17. Gartner, J., G. Jimenez-Sanchez, P. Roerig, and D. Valle. 1998. Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1). Genomics. 48:203-208.
18. Gorgas, K., and S.K. Krisans. 1989. Zonal heterogeneity of peroxisome proliferation and morphology in rat liver after gemfibrozil treatment. J. Lipid Res. 30:1859-1875.
19. Holzinger, A., S. Kammerer, and A.A. Roscher. 1997. Primary structure of human PMP69, a putative peroxisomal ABC-transporter. Biochem. Biophys. Res. Commun. 237:152-157.
20. Jin, S., and K.W. Scotto. 1998. Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y. Mol. Cell. Biol. 18:4377-4384.
21. Kamijo, K., S. Taketani, S. Yokota, T. Osumi, and T. Hashimoto. 1990. The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)- related ATP-binding protein superfamily. J. Biol. Chem. 265:4534-4540.
22. Kemp, S., H.M. Wei, J.F. Lu, L.T. Braiterman, M.C. McGuinness, A.B. Moser, P.A. Watkins, and K.D. Smith. 1998. Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy. Nat. Med. 4:1261-1268.
23. Kerckaert, I., D. De Craemer, and G. Van Limbergen. 1995. Practical guide for morphometry of human peroxisomes on electron micrographs. J. Inherit. Metab. Dis. 18:172-180.
24. Lea, M.A., and V.M. Randolph. 1998. Induction of reporter gene expression by inhibitors of histone deacetylase. Anticancer Res. 18:2717-2722.
25. Lee, S.S.-T., T. Pineau, J. Drago, E.J. Lee, J.W. Owens, D.L. Kroetz, P.M. Fernandez-Salguero, H. Westphal, and F.G. Gonzalez. 1995. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15:3012-3022.
26. Lemberger, T., O., Braissant, C. Juge-Aubry, H. Keller, R. Saladin, B. Staels, J. Auwerx, A.G. Burger, C.A. Meier, and W. Wahli. 1996. PPAR tissue distribution and interactions with other hormone-signaling pathways. Ann. NY Acad. Sci. 804:231-251.
27. Li, X., and S.J. Gould. 2002. PEX11 promotes peroxisome division independently of peroxisome metabolism. J. Cell Biol. 156:643-651.
28. Li, X., E. Baumgart, G.-X. Dong, J.C. Morrell, G. Jimenez-Sanchez, D. Valle, K.D. Smith, and S.J. Gould. 2002. PEX11α is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor α-mediated peroxisome proliferation. Mol. Cell. Biol. 22:8226-8240.
29. Liu, N., W. Qiang, X. Kuang, P. Thuillieer, W.S. Lynn, and P.K.Y. Wong. 2002. The peroxisome proliferator phenylbutyric acid (PBA) protects astrocytes from ts1 MoMuLV-induced oxidative cell death. J. Neurovirol. 8:318-325.
30. Lombard-Platet, G., S. Savary, C.O. Sarde, J.L. Mandel, and G. Chimini. 1996. A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. Proc. Natl. Acad. Sci. USA. 93:1265-1269.
31. Lu, Y., and R. Lotan. 1999. Transcriptional regulation by butyrate of mouse galectin-1 gene in embryonal carcinoma cells. Biochim. Biophys. Acta. 1444:85-91.
32. Marks, P.A., T. Miller, and V.M. Richon. 2003. Histone deacetylases. Curr. Opin. Pharmacol. 3:344-351.
33. Maslansky, C.J., and G.M. Williams. 1982. Primary cultures and the levels of cytochrome P450 in hepatocytes from mouse, rat, hamster and rabbit liver. In Vitro. 18:683-693.
34. McCaffrey, P.G., D.A. Newsome, E. Fibach, M. Yoshida, and M.S. Su. 1997. Induction of gamma-globin by histone deacetylase inhibitors. Blood. 90:2075-2083.
35. McGuinness, M.C., H.P. Zhang, and K.D. Smith. 2001. Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. Mol. Genet. Metab. 74:256-263.
36. Moser, H.W., K.D. Smith, P.A. Watkins, J. Powers, and A.B. Moser. 2001. X-linked adrenoleukodystrophy. In The Metabolic & Molecular Bases of Inherited Disease, 8th edition. R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill Inc., New York. 3257-3301.
37. Mosser, J., A.M. Douar, C.O. Sarde, P. Kioschis, R. Feil, H. Moser, A.M. Poustka, J.L. Mandel, and P. Aubourg. 1993. Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters. Nature. 361:726-730.
38. Motojima, K. 1997. Peroxisome proliferator-activated receptor (PPAR)-dependent and -independent transcriptional modulation of several non-peroxisomal genes by peroxisome proliferators. Biochimie. 79:101-106.
39. Nakayama, T., and Y. Takami. 2001. Participation of histones and histone-modifying enzymes in cell functions through alterations in chromatin structure. J. Biochem. (Tokyo). 129:491-499.
40. Netik, A., S. Forss-Petter, A. Holzinger, B. Molzer, G. Unterrainer, and J. Berger. 1999. Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy. Hum. Mol. Genet. 8:907-913.
41. Park, S.H, S.R. Lee, B.C. Kim, E.A. Cho, S.P. Patel, H.B. Kang, E.A. Sausville, O. Nakanishi, J.B. Trepel, B.I. Lee, S.J. Kim. 2002. Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. J. Biol. Chem. 15:277:5168-5174.
42. Passreiter, M., M. Anton, D. Lay, R. Frank, C. Harter, F.T. Wieland, K. Gorgas, and W.W. Just. 1998. Peroxisome biogenesis: involvement of ARF and coatomer. J. Cell Biol. 141:373-383.
43. Pineau, T., W.R. Hudgins, L. Liu, L.C. Chen, T. Sher, F.J. Gonzalez, and D. Samid. 1996. Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs. Biochem. Pharmacol. 52:659-667.
44. Pujol, A., I. Ferrer, C. Camps, E. Metzger, C. Hindelang, N. Callizot, M. Ruiz, T. Pampols, M. Giros, and J.L. Mandel. 2004. Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy. Hum. Mol. Genet. 13:2997-3006.
45. Roels, F. 1991. Peroxisomes: A Personal Account. VUB Press, Brussels. 151 pp.
46. Roels, F., B. De Prest, and G. De Pestel. 1995. Liver and chorion cytochemistry. J. Inherit. Metab. Dis. 18:155-171.
47. Schrader, M., B.E. Reuber, J.C. Morrell, G. Jimenez-Sanchez, C. Obie, T.A. Stroh, D. Valle, T.A. Schroer, and S.J. Gould. 1998. Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli. J. Biol. Chem. 273:29607-29614.
48. Schuettengruber, B., E. Simboek, H. Khier, and C. Seiser. 2003. Autoregulation of mouse histone deacetylase 1 expression. Mol. Cell. Biol. 23:6993-7004.
49. Soutoglou, E., B. Viollet, M. Vaxillaire, M. Yaniv, M. Pontoglio, and I. Talianidis. 2001. Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity. EMBO J. 20:1984-1992.
50. Svoboda, D.J., and D.L. Azarnoff. 1966. Response of hepatic microbodies to a hypolipidemic agent, ethyl chlorphenoxyisobutyrate (CPIB). J. Cell Biol. 30:442-450.
51. Waddell, W.J., C. Marlowe, M.S. Rao, and J.K. Reddy. 1989. In vivo distribution of a carcinogenic hepatic peroxisome proliferator: whole-body autoradiography of [14C]ciprofibrate in the mouse. Carcinogenesis. 10:221-223.
52. Warrell, R.P.J., L.Z. He, V. Richon, E. Calleja, and P.P. Pandolfi. 1998. Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J. Natl. Cancer Inst. 90:1621-1625.