Enhanced Sensitivity to Low Dose Irradiation of ApoE-/- Mice Mediated by Early Pro-Inflammatory Profile and Delayed Activation of the TGFβ1 Cascade Involved in Fibrogenesis

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Monceau, Virginie ^a,b,c,d   Meziani, Lydia ^a,b,c   Strup Perrot, Carine ^d   Morel, Eric ^e   Schmidt, Magret ^f   Haagen, Julia ^f   Escoubet, Brigitte ^g,h,i   Dörr, Wolfgang ^f,j   Vozenin, Marie Catherine ^a,b,c  

^a Institut Gustave Roussy   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d LRTE/SRBE/DRPH   (France)

^e INSERM   (France)

^f DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^g BICHAT HOSPITAL   (France)

^h UNIVERSITÉ PARIS DESCARTES   (France)

ⁱ CENTRE DE RECHERCHE DES CORDELIERS   (France)

^j INSTITUTE FOR MICROELECTRONICS   (Austria)

more..

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUSE OF DEATH; CELL POLARITY; CONTROLLED STUDY; CYTOKINE RELEASE; ECHOCARDIOGRAPHY; FIBROGENESIS; HEART INJURY; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART WEIGHT; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; LOW ENERGY RADIATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; SURVIVAL RATE; WILD TYPE;

ANIMALS; APOLIPOPROTEINS E; BLOTTING, WESTERN; DOSE-RESPONSE RELATIONSHIP, RADIATION; FIBROSIS; INFLAMMATION MEDIATORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84874297633     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057052     Document Type: Article

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