-
1
-
-
0029065391
-
The red wine phenolics transresveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease
-
Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics transresveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-219.
-
(1995)
Clin Chim Acta
, vol.235
, pp. 207-219
-
-
Pace-Asciak, C.R.1
Hahn, S.2
Diamandis, E.P.3
-
2
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006;444:337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
-
3
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
-
Lagouge M, Argmann C, Gerhart-Hines Z, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell 2006;127:1109-1122.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
-
4
-
-
20344394925
-
Resveratrol and breast cancer chemoprevention: Molecular mechanisms
-
Le Corre L, Chalabi N, Delort L, et al. Resveratrol and breast cancer chemoprevention: Molecular mechanisms. Mol Nutr Food Res 2005;49:462-471.
-
(2005)
Mol Nutr Food Res
, vol.49
, pp. 462-471
-
-
Le Corre, L.1
Chalabi, N.2
Delort, L.3
-
5
-
-
5744234431
-
The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human SK-Mel-28 melanoma cells
-
Larrosa M, Tomas-Barberan FA, Espin JC. The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human SK-Mel-28 melanoma cells. Eur J Nutr 2004;43:275-284.
-
(2004)
Eur J Nutr
, vol.43
, pp. 275-284
-
-
Larrosa, M.1
Tomas-Barberan, F.A.2
Espin, J.C.3
-
6
-
-
16244417790
-
New anticancer agents: In vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants
-
Kimura Y. New anticancer agents: In vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants. In Vivo 2005;19:37-60.
-
(2005)
In Vivo
, vol.19
, pp. 37-60
-
-
Kimura, Y.1
-
7
-
-
14844312113
-
Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling
-
Fulda S, Debatin KM. Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling. Eur J Cancer 2005;41:786-798.
-
(2005)
Eur J Cancer
, vol.41
, pp. 786-798
-
-
Fulda, S.1
Debatin, K.M.2
-
8
-
-
18844387903
-
The cancer chemopreventive agent resveratrol induces tensin, a cell-matrix adhesion protein with signaling and antitumor activities
-
Rodrigue CM, Porteu F, Navarro N, et al. The cancer chemopreventive agent resveratrol induces tensin, a cell-matrix adhesion protein with signaling and antitumor activities. Oncogene 2005;24:3274-3284.
-
(2005)
Oncogene
, vol.24
, pp. 3274-3284
-
-
Rodrigue, C.M.1
Porteu, F.2
Navarro, N.3
-
9
-
-
14644437724
-
Resveratrol and estradiol exert disparate effects on cell migration, cell surface actin structures, and focal adhesion assembly in MDA-MB-231 human breast cancer cells
-
Azios NG, Dharmawardhane SF. Resveratrol and estradiol exert disparate effects on cell migration, cell surface actin structures, and focal adhesion assembly in MDA-MB-231 human breast cancer cells. Neoplasia 2005;7:128-140.
-
(2005)
Neoplasia
, vol.7
, pp. 128-140
-
-
Azios, N.G.1
Dharmawardhane, S.F.2
-
10
-
-
15244340234
-
A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts
-
Gosslau A, Chen M, Ho CT, et al. A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts. Br J Cancer 2005;92:513-521.
-
(2005)
Br J Cancer
, vol.92
, pp. 513-521
-
-
Gosslau, A.1
Chen, M.2
Ho, C.T.3
-
11
-
-
17844388310
-
Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4′-trimethoxystilbene
-
Belleri M, Ribatti D, Nicoli S, et al. Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4′-trimethoxystilbene. Mol Pharmacol 2005;67:1451-1459.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1451-1459
-
-
Belleri, M.1
Ribatti, D.2
Nicoli, S.3
-
12
-
-
0041342053
-
Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents
-
Roberti M, Pizzirani D, Simoni D, et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. J Med Chem 2003;46:3546-3554.
-
(2003)
J Med Chem
, vol.46
, pp. 3546-3554
-
-
Roberti, M.1
Pizzirani, D.2
Simoni, D.3
-
13
-
-
0024513175
-
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
-
Pettit GR, Singh SB, Hamel E, et al. Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4. Experientia 1989;45: 209-211.
-
(1989)
Experientia
, vol.45
, pp. 209-211
-
-
Pettit, G.R.1
Singh, S.B.2
Hamel, E.3
-
14
-
-
9144254574
-
Microtubulin binding sites as target for developing anticancer agents
-
Islam MN, Iskander MN. Microtubulin binding sites as target for developing anticancer agents. Mini Rev Med Chem 2004;4:1077-1104.
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 1077-1104
-
-
Islam, M.N.1
Iskander, M.N.2
-
15
-
-
20044379059
-
Review: Tubulin function, action of antitubulin drugs, and new drug development
-
Pellegrini F, Budman DR. Review: Tubulin function, action of antitubulin drugs, and new drug development. Cancer Invest 2005;23:264-273.
-
(2005)
Cancer Invest
, vol.23
, pp. 264-273
-
-
Pellegrini, F.1
Budman, D.R.2
-
16
-
-
19544393159
-
Structural basis for the regulation of tubulin by vinblastine
-
Gigant B, Wang C, Ravelli RB, et al. Structural basis for the regulation of tubulin by vinblastine. Nature 2005;435:519-522.
-
(2005)
Nature
, vol.435
, pp. 519-522
-
-
Gigant, B.1
Wang, C.2
Ravelli, R.B.3
-
17
-
-
1642401199
-
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
-
Ravelli RB, Gigant B, Curmi PA, et al. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature 2004;428:198-202.
-
(2004)
Nature
, vol.428
, pp. 198-202
-
-
Ravelli, R.B.1
Gigant, B.2
Curmi, P.A.3
-
18
-
-
24944515311
-
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach
-
Nguyen TL, McGrath C, Hermone AR, et al. A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. J Med Chem 2005;48:6107-6116.
-
(2005)
J Med Chem
, vol.48
, pp. 6107-6116
-
-
Nguyen, T.L.1
McGrath, C.2
Hermone, A.R.3
-
19
-
-
0642307227
-
Phase I trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: Magnetic resonance imaging evidence for altered tumor blood flow
-
Stevenson JP, Rosen M, Sun W, et al. Phase I trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: Magnetic resonance imaging evidence for altered tumor blood flow. J Clin Oncol 2003;21:4428-4438.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4428-4438
-
-
Stevenson, J.P.1
Rosen, M.2
Sun, W.3
-
20
-
-
1642494772
-
Cardiovascular safety profile of combretastatin a4 phosphate in a single-dose phase I study in patients with advanced cancer
-
Cooney MM, Radivoyevitch T, Dowlati A, et al. Cardiovascular safety profile of combretastatin a4 phosphate in a single-dose phase I study in patients with advanced cancer. Clin Cancer Res 2004;10:96-100.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 96-100
-
-
Cooney, M.M.1
Radivoyevitch, T.2
Dowlati, A.3
-
21
-
-
0042386700
-
Phase I clinical trial of weekly combretastatin A4 phosphate: Clinical and pharmacokinetic results
-
Rustin GJ, Galbraith SM, Anderson H, et al. Phase I clinical trial of weekly combretastatin A4 phosphate: Clinical and pharmacokinetic results. J Clin Oncol 2003;21:2815-2822.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2815-2822
-
-
Rustin, G.J.1
Galbraith, S.M.2
Anderson, H.3
-
22
-
-
33645732100
-
Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors
-
Beerepoot LV, Radema SA, Witteveen EO, et al. Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors. J Clin Oncol 2006;24:1491-1498.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1491-1498
-
-
Beerepoot, L.V.1
Radema, S.A.2
Witteveen, E.O.3
-
23
-
-
0037096814
-
A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer
-
Dowlati A, Robertson K, Cooney M, et al. A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer. Cancer Res 2002;62:3408-3416.
-
(2002)
Cancer Res
, vol.62
, pp. 3408-3416
-
-
Dowlati, A.1
Robertson, K.2
Cooney, M.3
-
24
-
-
0033941680
-
Effects of combretastatin A-4 prodrug against a panel of malignant human B-lymphoid cell lines
-
Nabha SM, Wall NR, Mohammad RM, et al. Effects of combretastatin A-4 prodrug against a panel of malignant human B-lymphoid cell lines. Anticancer Drugs 2000;11:385-392.
-
(2000)
Anticancer Drugs
, vol.11
, pp. 385-392
-
-
Nabha, S.M.1
Wall, N.R.2
Mohammad, R.M.3
-
25
-
-
0036023440
-
Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage
-
Nabha SM, Mohammad RM, Dandashi MH, et al. Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage. Clin Cancer Res 2002;8:2735-2741.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2735-2741
-
-
Nabha, S.M.1
Mohammad, R.M.2
Dandashi, M.H.3
-
26
-
-
0035066012
-
Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5)
-
Garrido SM, Appelbaum FR, Willman CL, et al. Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5). Exp Hematol 2001;29:448-457.
-
(2001)
Exp Hematol
, vol.29
, pp. 448-457
-
-
Garrido, S.M.1
Appelbaum, F.R.2
Willman, C.L.3
-
27
-
-
0038717067
-
Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms
-
Nefedova Y, Landowski TH, Dalton WS. Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms. Leukemia 2003;17:1175-1182.
-
(2003)
Leukemia
, vol.17
, pp. 1175-1182
-
-
Nefedova, Y.1
Landowski, T.H.2
Dalton, W.S.3
-
28
-
-
0141816762
-
Variable hematopoietic graft rejection and graft-versus-host disease in MHC-matched strains of mice
-
Cao TM, Lo B, Ranheim EA, Grumet FC, et al. Variable hematopoietic graft rejection and graft-versus-host disease in MHC-matched strains of mice. Proc Natl Acad Sci USA 2003;100:11571-11576.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11571-11576
-
-
Cao, T.M.1
Lo, B.2
Ranheim, E.A.3
Grumet, F.C.4
-
29
-
-
0033119771
-
Combretastatin A-4 phosphate as a tumor vascular-targeting agent: Early effects in tumors and normal tissues
-
Tozer GM, Prise VE, Wilson J, et al. Combretastatin A-4 phosphate as a tumor vascular-targeting agent: Early effects in tumors and normal tissues. Cancer Res 1999;59:1626-1634.
-
(1999)
Cancer Res
, vol.59
, pp. 1626-1634
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
-
30
-
-
0842311621
-
Vascular targeting agents as cancer therapeutics
-
Thorpe PE. Vascular targeting agents as cancer therapeutics. Clin Cancer Res 2004;10:415-427.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 415-427
-
-
Thorpe, P.E.1
-
32
-
-
0036197311
-
Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI
-
Maxwell RJ, Wilson J, Prise VE, et al. Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI. NMR Biomed 2002;15:89-98.
-
(2002)
NMR Biomed
, vol.15
, pp. 89-98
-
-
Maxwell, R.J.1
Wilson, J.2
Prise, V.E.3
-
33
-
-
0042386691
-
Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging
-
Galbraith SM, Maxwell RJ, Lodge MA, et al. Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging. J Clin Oncol 2003;21:2831-2842.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2831-2842
-
-
Galbraith, S.M.1
Maxwell, R.J.2
Lodge, M.A.3
-
34
-
-
0042887593
-
Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate
-
Anderson HL, Yap JT, Miller MP, et al. Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate. J Clin Oncol 2003;21:2823-2830.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2823-2830
-
-
Anderson, H.L.1
Yap, J.T.2
Miller, M.P.3
-
35
-
-
0034109559
-
Combination chemotherapy with combretastatin A-4 phosphate and 5-fluorouracil in an experimental murine colon adenocarcinoma
-
Grosios K, Loadman PM, Swaine DJ, et al. Combination chemotherapy with combretastatin A-4 phosphate and 5-fluorouracil in an experimental murine colon adenocarcinoma. Anticancer Res 2000;20:229-233.
-
(2000)
Anticancer Res
, vol.20
, pp. 229-233
-
-
Grosios, K.1
Loadman, P.M.2
Swaine, D.J.3
-
36
-
-
0036568457
-
Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
-
Siemann DW, Mercer E, Lepler S, et al. Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int J Cancer 2002; 99:1-6.
-
(2002)
Int J Cancer
, vol.99
, pp. 1-6
-
-
Siemann, D.W.1
Mercer, E.2
Lepler, S.3
-
37
-
-
0142156049
-
Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response
-
Liu J, Dai Q, Chen J, et al. Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response. Mol Cancer Res 2003;1:892-902.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 892-902
-
-
Liu, J.1
Dai, Q.2
Chen, J.3
-
38
-
-
0037444392
-
Phospholipid scramblase 3 is the mitochondrial target of protein kinase c δ-induced apoptosis
-
Liu J, Chen J, Dai Q, et al. Phospholipid scramblase 3 is the mitochondrial target of protein kinase c δ-induced apoptosis. Cancer Res 2003;63:1153-1156.
-
(2003)
Cancer Res
, vol.63
, pp. 1153-1156
-
-
Liu, J.1
Chen, J.2
Dai, Q.3
-
39
-
-
29144440145
-
Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells
-
Karimi M, Cao TM, Baker JA, et al. Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells. J Immunol 2005;175:7819-7828.
-
(2005)
J Immunol
, vol.175
, pp. 7819-7828
-
-
Karimi, M.1
Cao, T.M.2
Baker, J.A.3
-
40
-
-
0031552362
-
Development and validation of a genetic algorithm for flexible docking
-
Jones G, Willett P, Glen RC, et al. Development and validation of a genetic algorithm for flexible docking. J Mol Biol 1997;267:727-748.
-
(1997)
J Mol Biol
, vol.267
, pp. 727-748
-
-
Jones, G.1
Willett, P.2
Glen, R.C.3
|