Low-dose radiation exposure and atherosclerosis in ApoE2-/-Mice

Radiation Research

Volumn 175, Issue 5, 2011, Pages 665-676

  Mitchel, R E J ^a   Hasu, M ^b,c   Bugden, M ^a   Wyatt, H ^a   Little, M P ^d   Gola, A ^e   Hildebrandt, G ^f   Priest, N D ^a   Whitman, S C ^b,c  

^a ATOMIC ENERGY OF CANADA LIMITED   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^d NATIONAL CANCER INSTITUTE   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; DISEASE COURSE; DISEASE SEVERITY; FEMALE; LOW ENERGY RADIATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; LIPID METABOLISM; MACROPHAGES; MICE; TIME FACTORS;

MUS;

EID: 79955413691     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR2176.1     Document Type: Article

References (34)

1. Y. Shimizu, D. A. Pierce, D. L. Preston and K. Mabuchi, Studies of the mortality of atomic bomb survivors. Report 12, part II. Noncancer mortality: 1950-1990. Radiat. Res. 152, 374-389 (1999). (Pubitemid 29463615)
2. M. Yamada, F. L. Wong, S. Fujiwara, M. Akahoshi and G. Suzuki, Noncancer disease incidence in atomic bomb survivors, 1958-1998. Radiat. Res. 161, 622-632 (2004). (Pubitemid 39149570)
3. D. L. Preston, Y. Shimizu, D. A. Pierce, A. Suyama and K. Mabuchi, Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997. Radiat. Res. 160, 381-407 (2003). (Pubitemid 37174507)
4. M. Yamada, K. Naito, F. Kasagi, N. Masunari and G. Suzuki, Prevalence of atherosclerosis in relation to atomic bomb radiation exposure: an RERF Adult Health Study. Int. J. Radiat. Biol. 81, 821-826 (2005). (Pubitemid 43244601)
5. Z. A. Carr, C. E. Land, R. A. Kleinerman, R. W. Weinstock, M. Stovall, M. L. Griem and K. Mabuchi, Coronary heart disease after radiotherapy for peptic ulcer disease. Int. J. Radiat. Oncol. Biol. Phys. 61, 842-850 (2005). (Pubitemid 40247980)
6. E. Shai, S. Siegals, Z. Michael, K. Itzhak, R. Ronen, M. Dror, B. Sylvia, B. H. Adina, A. H. Ramzia and B. Arie, Carotid atherosclerotic disease following childhood scalp irradiation. Atherosclerosis 204, 556-560 (2009).
7. S. Sadetzki, A. Chetrit, L. Freedman, M. Stovall, B. Modan and I. Novikov, Long-term follow-up for brain tumor development after childhood exposure to ionizing radiation for tinea capitis. Radiat. Res. 163, 424-432 (2005). (Pubitemid 40404651)
8. E. Ron, B. Modan, D. Preston, E. Alfandary, M. Stovall and J. D. Boice, Jr., Thyroid neoplasia following low-dose radiation in childhood. Radiat. Res. 120, 516-531 (1989). (Pubitemid 20022197)
9. G. R. Howe, L. B. Zablotska, J. J. Fix, J. Egel and J. Buchanan, Analysis of the mortality experience amongst U.S. nuclear power industry workers after chronic low-dose exposure to ionizing radiation. Radiat. Res. 162, 517-526 (2004). (Pubitemid 39600540)
10. M. P. Little, A. Gola and I. Tzoulaki, A model of cardiovascular disease giving a plausible mechanism for the effect of fractionated low-dose ionizing radiation exposure. PLoS Comput. Biol. 5, e1000539 (2009).
11. P. McGale and S. C. Darby, Low doses of ionizing radiation and circulatory diseases: a systematic review of the published epidemiological evidence. Radiat. Res. 163, 247-257 (2005). (Pubitemid 40293532)
12. R. Sponsler and J. R. Cameron, Nuclear shipyard worker study (1980-1988): a large cohort exposed to low-dose-rate gamma radiation. Int. J. Low Radiat. 1, 463-478 (2005).
13. M. Vrijheid, E. Cardis, P. Ashmore, A. Auvinen, J. M. Bae, H. Engels, E. Gilbert, G. Gulis, R. Habib and K. Veress, Mortality from diseases other than cancer following low doses of ionizing radiation: results from the 15-Country Study of nuclear industry workers. Int. J. Epidemiol. 36, 1126-1135 (2007). (Pubitemid 350018557)
14. D. L. Tribble, M. H. Barcellos-Hoff, B. M. Chu and E. L. Gong, Ionizing radiation accelerates aortic lesion formation in fat-fed mice via SOD-inhibitable processes. Arterioscler. Thromb. Vasc. Biol. 19, 1387-1392 (1999). (Pubitemid 29263007)
15. R. Pakala L. Leborgne, E. Cheneau, R. C. Chan, H. Yazdi, J. Fournadjiev, D. Weber, D. Hellinga, F. Kolodgie and R. Waksman, Radiation-induced atherosclerotic plaque progression in a hypercholesterolemic rabbit: a prospective vulnerable plaque model? Cardiovasc. Radiat. Med. 4, 146-151 (2003). (Pubitemid 38230307)
16. Y. Cottin, M. Kollum, F. D. Kolodgie, R. C. Chan, H. S. Kim, Y. Vodovotz, R. Virmani, R. Waksman and H. Yazdi, Intravascular radiation accelerates atherosclerotic lesion formation of hypercholesteremic rabbits. Cardiovasc. Radiat. Med. 2, 231-240 (2001). (Pubitemid 34838881)
17. M. Van Eck, N. Herijgers, J. Yates, N. J. Pearce, P. M. Hoogerbrugge, P. H. Groot and T. J. Van Berkel, Bone marrow transplantation in apolipoprotein E-deficient mice. Effect of ApoE gene dosage on serum lipid concentrations, (beta)VLDL catabolism, and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 17, 3117-3126 (1997). (Pubitemid 28016067)
18. F. A. Stewart, S. Heeneman, J. Te Poele, J. Kruse, N. S. Russell, M. Gijbels and M. Daemen, Ionizing radiation accelerates the development of atherosclerotic lesions in ApoE2/2 mice and predisposes to an inflammatory plaque phenotype prone to hemorrhage. Am. J. Pathol. 168, 649-658 (2006). (Pubitemid 43271162)
19. S. Hoving, S. Heeneman, M. J. Gijbels, J. A. te Poele, N. S. Russell, M. J. Daemen and F. A. Stewart, Single-dose and fractionated irradiation promote initiation and progression of atherosclerosis and induce an inflammatory plaque phenotype in ApoE2/2 mice. Int. J. Radiat. Oncol. Biol. Phys. 71, 848-857 (2008). (Pubitemid 351749524)
20. N. K. Schiller, N. Kubo, W. A. Boisvert and L. K. Curtiss, Effect of gamma-irradiation and bone marrow transplantation on atherosclerosis in LDL receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 10, 1674-1680 (2001). (Pubitemid 34215590)
21. J. A Piedrahita, S. H. Zhang, J. R. Hagaman, P. M. Oliver and N. Maeda, Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. USA 89, 4471-4475 (1992).
22. A. S. Plump, J. D. Smith, T. Hayek, K. Aalto-Setala, A. Walsh, J. G. Verstuyft, E. M. Rubin and J. L. Breslow, Severe hypercholesterolemia and atherosclerosis in apolipoprotein Edeficient mice created by homologous recombination in ES cells. Cell 71, 343-353 (1992).
23. Y. Nakashima, A. S. Plump, E. W. Raines, J. L. Breslow and R. Ross, ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 14, 133-140 (1994).
24. H. C. Stary, Macrophages, macrophage foam cells, and eccentric intimal thickening in the coronary arteries of young children. Atherosclerosis 64, 91-108 (1987). (Pubitemid 17047149)
25. H. C. Stary, The sequence of cell and matrix changes in atherosclerotic lesions of coronary arteries in the first forty years of life. Eur. Heart J. 11 (Suppl. E), 3-19 (1990). (Pubitemid 20287937)
26. H. C. Stary, Composition and classification of human atherosclerotic lesions. Virchows Arch. A Pathol. Anat. Histopathol. 421, 277-290 (1992).
27. S. C. Whitman, P. Ravisankar and A. Daugherty, IFN-gamma deficiency exerts gender-specific effects on atherogenesis in apolipoprotein E2/2 mice. J. Interferon Cytokine Res. 22, 661-670 (2002). (Pubitemid 35034524)
28. S. C. Whitman, P. Ravisankar and A. Daugherty, Interleukin-18 enhances atherosclerosis in apolipoprotein E2/2 mice through release of interferon-gamma. Circ. Res. 90, E34-E38 (2002).
29. S. C. Whitman, P. Ravisankar, H. Elam and A. Daugherty, Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E2/2 mice. Am. J. Pathol. 157, 1819-1824 (2000).
30. A. Daugherty and S. C. Whitman, Quantification of atherosclerosis in mice. Methods Mol. Biol. 209, 293-309 (2003).
31. S. C. Whitman, D. L. Rateri, S. J. Szilvassy, W. Yokoyama and A. Daugherty, Depletion of natural killer cell function decreases atherosclerosis in low-density lipoprotein receptor null mice. Arterioscler. Thromb. Vasc. Biol. 6, 1049-1054 (2004). (Pubitemid 38737830)
32. H. C. Stary, A. B. Chandler, S. Glagov, J. R. Guyton, W. Insull, Jr., M. E. Rosenfeld, S. A. Schaffer, C. J. Schwartz, W. D. Wagner and R. W. Wissler, A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 89, 2462-2478 (1994). (Pubitemid 24142837)
33. H. C. Stary, A. B. Chandler, R. E. Dinsmore, V. Fuster, S. Glagov, W. Insull, Jr., M. E. Rosenfeld, C. J. Schwartz, W. D. Wagner and R. W. Wissler, A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 92, 1355-1374 (1995).
34. Y. Shimizu, K. Kodama, N. Nishi, F. Kasagi, A. Suyama, M. Soda, E. J. Grant, H. Sugiyama, R. Sakata and R. E. Shore, Radiation exposure and circulatory disease risk: Hiroshima and Nagasaki atomic bomb survivor data, 1950-2003. BMJ 340, b5349 (2010).