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Volumn 3, Issue 8, 2008, Pages 815-818

The insulin-like growth factor pathway in lung cancer

Author keywords

Insulin like growth factor, lung cancer

Indexed keywords

AMG 479; CARBOPLATIN; CP 751871; ERLOTINIB; GEFITINIB; IMC A12; INSM 18; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; OSI 906; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; R 1507; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; XL 228;

EID: 58149107984     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e31818180f5     Document Type: Article
Times cited : (82)

References (33)
  • 1
    • 34848845313 scopus 로고    scopus 로고
    • Modifying IGF1 activity: An approach to treat endocrine disorders, atherosclerosis and cancer
    • Clemmons DR. Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer. Nat Rev Drug Discov 2007;6:821-833.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 821-833
    • Clemmons, D.R.1
  • 2
    • 40749128979 scopus 로고    scopus 로고
    • IGF2: Epigenetic regulation and role in development and disease
    • Chao W, D'Amore PA. IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev 2008;19:111-120.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 111-120
    • Chao, W.1    D'Amore, P.A.2
  • 4
    • 38049009418 scopus 로고    scopus 로고
    • Structure and functional analysis of the IGF-II/IGF2R interaction
    • Brown J, Delaine C, Zaccheo OJ, et al. Structure and functional analysis of the IGF-II/IGF2R interaction. EMBO J 2008;27:265-276.
    • (2008) EMBO J , vol.27 , pp. 265-276
    • Brown, J.1    Delaine, C.2    Zaccheo, O.J.3
  • 5
    • 33845230171 scopus 로고    scopus 로고
    • Antimetastatic activity of insulinlike growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition
    • Oh SH, Lee OH, Schroeder CP, et al. Antimetastatic activity of insulinlike growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition. Mol Cancer Ther 2006;5:2685-2695.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2685-2695
    • Oh, S.H.1    Lee, O.H.2    Schroeder, C.P.3
  • 6
    • 33750571170 scopus 로고    scopus 로고
    • Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib
    • Morgillo F, Woo JK, Kim ES, Hong WK, Lee HY. Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib. Cancer Res 2006;66:10100-10111.
    • (2006) Cancer Res , vol.66 , pp. 10100-10111
    • Morgillo, F.1    Woo, J.K.2    Kim, E.S.3    Hong, W.K.4    Lee, H.Y.5
  • 7
    • 33344467985 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor pathways
    • Yee D. Targeting insulin-like growth factor pathways. Br J Cancer 2006;94:465-468.
    • (2006) Br J Cancer , vol.94 , pp. 465-468
    • Yee, D.1
  • 8
    • 0742304062 scopus 로고    scopus 로고
    • Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression
    • Zhang X, Kamaraju S, Hakuno F, et al. Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression. Breast Cancer Res Treat 2004;83:161-170.
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 161-170
    • Zhang, X.1    Kamaraju, S.2    Hakuno, F.3
  • 9
    • 23044493251 scopus 로고    scopus 로고
    • Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
    • Hofmann F, Garcia-Echeverria C. Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer. Drug Discov Today 2005;10:1041-1047.
    • (2005) Drug Discov Today , vol.10 , pp. 1041-1047
    • Hofmann, F.1    Garcia-Echeverria, C.2
  • 10
    • 35148837581 scopus 로고    scopus 로고
    • Mechanisms of disease: Signaling of the insulin-like growth factor 1 receptor pathway - therapeutic perspectives in cancer
    • Tao Y, Pinzi V, Bourhis J, Deutsch E. Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway - therapeutic perspectives in cancer. Nat Clin Pract Oncol 2007;4:591-602.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 591-602
    • Tao, Y.1    Pinzi, V.2    Bourhis, J.3    Deutsch, E.4
  • 11
    • 0033585421 scopus 로고    scopus 로고
    • Plasma levels of insulin-like growth factor-I and lung cancer risk: A case-control analysis
    • Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X. Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst 1999;91:151-156.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 151-156
    • Yu, H.1    Spitz, M.R.2    Mistry, J.3    Gu, J.4    Hong, W.K.5    Wu, X.6
  • 12
    • 0037094239 scopus 로고    scopus 로고
    • Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China
    • London SJ, Yuan JM, Travlos GS, et al. Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China. J Natl Cancer Inst 2002;94:749-754.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 749-754
    • London, S.J.1    Yuan, J.M.2    Travlos, G.S.3
  • 13
    • 0036894939 scopus 로고    scopus 로고
    • Correlation between insulin-like growth factor-binding protein-3 promoter methylation and prognosis of patients with stage I non-small cell lung cancer
    • Chang YS, Wang L, Liu D, et al. Correlation between insulin-like growth factor-binding protein-3 promoter methylation and prognosis of patients with stage I non-small cell lung cancer. Clin Cancer Res 2002;8:3669-3675.
    • (2002) Clin Cancer Res , vol.8 , pp. 3669-3675
    • Chang, Y.S.1    Wang, L.2    Liu, D.3
  • 14
    • 33744785962 scopus 로고    scopus 로고
    • Variants in the GH-IGF axis confer susceptibility to lung cancer
    • Rudd MF, Webb EL, Matakidou A, et al. Variants in the GH-IGF axis confer susceptibility to lung cancer. Genome Res 2006;16:693-701.
    • (2006) Genome Res , vol.16 , pp. 693-701
    • Rudd, M.F.1    Webb, E.L.2    Matakidou, A.3
  • 15
    • 34548018304 scopus 로고    scopus 로고
    • The insulin-like growth factor 1 receptor in cancer: Old focus, new future
    • Hartog H, Wesseling J, Boezen HM, van der Graaf WT. The insulin-like growth factor 1 receptor in cancer: old focus, new future. Eur J Cancer 2007;43:1895-1904.
    • (2007) Eur J Cancer , vol.43 , pp. 1895-1904
    • Hartog, H.1    Wesseling, J.2    Boezen, H.M.3    van der Graaf, W.T.4
  • 16
    • 20944440088 scopus 로고    scopus 로고
    • Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor
    • Carboni JM, Lee AV, Hadsell DL, et al. Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor. Cancer Res 2005;65:3781-3787.
    • (2005) Cancer Res , vol.65 , pp. 3781-3787
    • Carboni, J.M.1    Lee, A.V.2    Hadsell, D.L.3
  • 17
    • 0037434663 scopus 로고    scopus 로고
    • Transgenic overexpression of IGF-II induces spontaneous lung tumors: A model for human lung adenocarcinoma
    • Moorehead RA, Sanchez OH, Baldwin RM, Khokha R. Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma. Oncogene 2003;22:853-857.
    • (2003) Oncogene , vol.22 , pp. 853-857
    • Moorehead, R.A.1    Sanchez, O.H.2    Baldwin, R.M.3    Khokha, R.4
  • 18
    • 38849088141 scopus 로고    scopus 로고
    • The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer
    • Ryan PD, Goss PE. The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer. Oncologist 2008;13:16-24.
    • (2008) Oncologist , vol.13 , pp. 16-24
    • Ryan, P.D.1    Goss, P.E.2
  • 19
    • 33846807433 scopus 로고    scopus 로고
    • Disrupting insulin-like growth factor signaling as a potential cancer therapy
    • Sachdev D, Yee D. Disrupting insulin-like growth factor signaling as a potential cancer therapy. Mol Cancer Ther 2007;6:1-12.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1-12
    • Sachdev, D.1    Yee, D.2
  • 20
    • 20144386856 scopus 로고    scopus 로고
    • Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871
    • Cohen BD, Baker DA, Soderstrom C, et al. Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871. Clin Cancer Res 2005;11:2063-2073.
    • (2005) Clin Cancer Res , vol.11 , pp. 2063-2073
    • Cohen, B.D.1    Baker, D.A.2    Soderstrom, C.3
  • 21
    • 34548058890 scopus 로고    scopus 로고
    • A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo
    • Ji QS, Mulvihill MJ, Rosenfeld-Franklin M, et al. A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo. Mol Cancer Ther 2007;6:2158-2167.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2158-2167
    • Ji, Q.S.1    Mulvihill, M.J.2    Rosenfeld-Franklin, M.3
  • 23
    • 1642586272 scopus 로고    scopus 로고
    • Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
    • Wendel HG, De Stanchina E, Fridman JS, et al. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 2004;428: 332-337.
    • (2004) Nature , vol.428 , pp. 332-337
    • Wendel, H.G.1    De Stanchina, E.2    Fridman, J.S.3
  • 24
    • 10344247119 scopus 로고    scopus 로고
    • A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts
    • Goetsch L, Gonzalez A, Leger O, et al. A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts. Int J Cancer 2005;113:316-328.
    • (2005) Int J Cancer , vol.113 , pp. 316-328
    • Goetsch, L.1    Gonzalez, A.2    Leger, O.3
  • 26
    • 14644433735 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
    • Warshamana-Greene GS, Litz J, Buchdunger E, García- Echeverría C, Hofmann F, Krystal GW. The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy. Clin Cancer Res 2005;11:1563-1571.
    • (2005) Clin Cancer Res , vol.11 , pp. 1563-1571
    • Warshamana-Greene, G.S.1    Litz, J.2    Buchdunger, E.3    García- Echeverría, C.4    Hofmann, F.5    Krystal, G.W.6
  • 27
    • 34249049000 scopus 로고    scopus 로고
    • Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib
    • Morgillo F, Kim WY, Kim ES, Ciardiello F, Hong WK, Lee HY. Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib. Clin Cancer Res 2007;13:2795-2803.
    • (2007) Clin Cancer Res , vol.13 , pp. 2795-2803
    • Morgillo, F.1    Kim, W.Y.2    Kim, E.S.3    Ciardiello, F.4    Hong, W.K.5    Lee, H.Y.6
  • 28
    • 33847041527 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signaling blockade combined with radiation
    • Allen GW, Saba C, Armstrong EA, et al. Insulin-like growth factor-I receptor signaling blockade combined with radiation. Cancer Res 2007; 67:1155-1162.
    • (2007) Cancer Res , vol.67 , pp. 1155-1162
    • Allen, G.W.1    Saba, C.2    Armstrong, E.A.3
  • 29
    • 34247140280 scopus 로고    scopus 로고
    • Ionizing radiation activates IGF-1R triggering a cytoprotective signaling by interfering with Ku-DNA binding and by modulating Ku86 expression via a p38 kinase-dependent mechanism
    • Cosaceanu D, Budiu RA, Carapancea M, Castro J, Lewensohn R, Dricu A. Ionizing radiation activates IGF-1R triggering a cytoprotective signaling by interfering with Ku-DNA binding and by modulating Ku86 expression via a p38 kinase-dependent mechanism. Oncogene 2007;26: 2423-2434.
    • (2007) Oncogene , vol.26 , pp. 2423-2434
    • Cosaceanu, D.1    Budiu, R.A.2    Carapancea, M.3    Castro, J.4    Lewensohn, R.5    Dricu, A.6
  • 30
    • 35348815620 scopus 로고    scopus 로고
    • Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors
    • Haluska P, Shaw HM, Batzel GN, et al. Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors. Clin Cancer Res 2007;13:5834-5840.
    • (2007) Clin Cancer Res , vol.13 , pp. 5834-5840
    • Haluska, P.1    Shaw, H.M.2    Batzel, G.N.3
  • 31
    • 36348954086 scopus 로고    scopus 로고
    • Efficacy of the anti-insulin like growth factor I receptor (IGF-IR) antibody CP-751871 in combination with paclitaxel and carboplatin as first-line treatment for advanced non-small cell lung cancer (NSCLC)
    • Karp DD, Paz-Ares LG, Blakely LJ, et al. Efficacy of the anti-insulin like growth factor I receptor (IGF-IR) antibody CP-751871 in combination with paclitaxel and carboplatin as first-line treatment for advanced non-small cell lung cancer (NSCLC). J Clin Oncol. ASCO Annu Meet Proc Part I 2007;25(18S):7506.
    • (2007) J Clin Oncol. ASCO Annu Meet Proc Part I , vol.25 , Issue.18 S , pp. 7506
    • Karp, D.D.1    Paz-Ares, L.G.2    Blakely, L.J.3
  • 32
    • 67650981912 scopus 로고    scopus 로고
    • Leong S, Gore L, Benjamin R, et al. A phase I study of R1507, a human monoclonal antibody IGF-1R (insulin-like growth factor receptor) antagonist given weekly in patients with advanced solid tumors. In Proceedings of AACR-NCI-EORTC International Conference Molecular Tergets and Cancer Therapeutics, San Francisco, Oct. 22-26, 2007:A78.
    • Leong S, Gore L, Benjamin R, et al. A phase I study of R1507, a human monoclonal antibody IGF-1R (insulin-like growth factor receptor) antagonist given weekly in patients with advanced solid tumors. In Proceedings of AACR-NCI-EORTC International Conference "Molecular Tergets and Cancer Therapeutics", San Francisco, Oct. 22-26, 2007:A78.
  • 33
    • 36148976199 scopus 로고    scopus 로고
    • A phase I pharmacokinetic and pharmacodynamic study of AMG 479, a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R), in advanced solid tumors
    • Tolcher AW, Rothenberg ML, Rodon J, et al. A phase I pharmacokinetic and pharmacodynamic study of AMG 479, a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R), in advanced solid tumors. J Clin Oncol. ASCO Annu Meet Proc Part I 2007;25(18S):3002.
    • (2007) J Clin Oncol. ASCO Annu Meet Proc Part I , vol.25 , Issue.18 S , pp. 3002
    • Tolcher, A.W.1    Rothenberg, M.L.2    Rodon, J.3


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