Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells

Journal of Cellular Biochemistry

Volumn 106, Issue 6, 2009, Pages 1113-1122

  Lee, Dae Hee ^a   Szczepanski, Miroslaw Jerzy ^b   Lee, Yong J ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Apoptosis; Bad; Bax; EGFR; Magnolol; PI3K Akt pathway

Indexed keywords

CYTOCHROME C; EPIDERMAL GROWTH FACTOR RECEPTOR; MAGNOLOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CYTOCHROMES C; EPIDERMAL GROWTH FACTOR; HUMANS; LIGNANS; MALE; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

MAGNOLIA OFFICINALIS;

EID: 66149089933     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22098     Document Type: Article

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