Involvement of Ras/Raf-1/ERK actions in the magnolol-induced upregulation of p21 and cell-cycle arrest in colon cancer cells

Molecular Carcinogenesis

Volumn 46, Issue 4, 2007, Pages 275-283

  Hsu, Yi Fan ^a   Lee, Tong Sheng ^a,c   Lin, Shyr Yi ^a   Hsu, Sung Po ^b   Juan, Shu Hui ^a   Hsu, Yuan N ^a   Zhong, Wen Bin ^a   Lee, Wen Sen ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Colon cancer; ERK; p21; Raf; Ras

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; MAGNOLOL; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE INHIBITOR; PROTEIN P21; RAF PROTEIN; RAS PROTEIN; THYMIDINE;

ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE ARREST; COLON CANCER; CONTROLLED STUDY; DNA SYNTHESIS; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BIPHENYL COMPOUNDS; CELL CYCLE; CELL LINE, TUMOR; COLONIC NEOPLASMS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIGNANS; NITRIC OXIDE SYNTHASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 34247191560     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20274     Document Type: Article

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