An Extract of Artemisia dracunculus L. Inhibits Ubiquitin-Proteasome Activity and Preserves Skeletal Muscle Mass in a Murine Model of Diabetes

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Kirk Ballard, Heather ^a   Wang, Zhong Q ^a   Acharya, Priyanka ^a   Zhang, Xian H ^a   Yu, Yongmei ^a   Kilroy, Gail ^a   Ribnicky, David ^b   Cefalu, William T ^a   Floyd, Z Elizabeth ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISIA DRACUNCULUS EXTRACT; ATROGIN 1; DEXAMETHASONE; INSULIN; MUSCLE RING FINGER 1 PROTEIN; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEASOME; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTEMISIA DRACUNCULUS; ARTICLE; CELL SIZE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MODEL; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MOUSE; MUSCLE CELL; MUSCLE MASS; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STEADY STATE; UBIQUITINATION; UPREGULATION;

ANIMALS; ARTEMISIA; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FATTY ACIDS; GENE EXPRESSION REGULATION; INSULIN RESISTANCE; MALE; MICE; MUSCLE FIBERS, SKELETAL; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84874273753     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057112     Document Type: Article

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