Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages 3041-3046

  Bachy, Veronique ^a   Hervouet, Catherine ^a   Becker, Pablo D ^a   Chorro, Laurent ^a   Carlin, Leo M ^a   Herath, Shanthi ^a   Papagatsias, Timos ^b   Barbaroux, Jean Baptiste ^c   Oh, Sea Jin ^d   Benlahrech, Adel ^b   Athanasopoulos, Takis ^e   Dickson, George ^e   Patterson, Steven ^b   Kwon, Sung Yun ^d   Geissmann, Frederic ^a   Klavinskis, Linda S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

^d TheraJect Inc   (United States)

^e UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VACCINE; CD11B ANTIGEN; CD8 ANTIGEN; EPITHELIAL CELL ADHESION MOLECULE; GLYCOPROTEIN P 15095; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LANGERIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RESPONSE; DENDRITIC CELL; DERMIS; DRUG DELIVERY SYSTEM; EPIDERMIS; HUMAN ADENOVIRUS 5; IMMUNIZATION; IMMUNOGENICITY; LANGERHANS CELL; MICRONEEDLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN PENETRATION; THERMOSTABILITY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANTIGENS, CD; CD8-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; GENETIC VECTORS; LECTINS, C-TYPE; MANNOSE-BINDING LECTINS; MICROSCOPY, CONFOCAL; NEEDLES; SKIN; VIRAL VACCINES;

EID: 84874264275     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214449110     Document Type: Article

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