Transforming growth factor-beta 2 causes an acute improvement in the motor performance of transgenic ALS mice

Neurobiology of Disease

Volumn 19, Issue 1-2, 2005, Pages 323-330

  Day, W Antony ^a,c   Koishi, Kyoko ^a   Nukuda, Hitoshi ^b   McLennan, Ian S ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Amyotrophic lateral sclerosis; Cell death; Cell size; Mitochondria; Motor performance; Nucleoli; Transforming growth factor beta 2

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA2;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CADAVER; CELL DAMAGE; CELL DEATH; CELL NUCLEUS; CELL ORGANELLE; CELL SIZE; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; HYPERTROPHY; MALE; METABOLIC RATE; MOTONEURON; MOTOR PERFORMANCE; MOUSE; NERVE FIBER; NONHUMAN; NUCLEOLUS; PATHOLOGY; PRIORITY JOURNAL; TIME SERIES ANALYSIS; TRANSGENIC MOUSE;

EID: 17544370466     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.01.010     Document Type: Article

References (47)

1. G. Acsadi, R.A. Anguelov, H. Yang, G. Toth, R. Thomas, A. Jani, Y. Wang, E. Ianakova, S. Mohammad, R.A. Lewis, and M.E. Shy Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy Hum. Gene Ther. 13 2002 1047 1059
2. M. Azzouz, G.S. Ralph, E. Storkebaum, L.E. Walmsley, K.A. Mitrophanous, S.M. Kingsman, P. Carmeliet, and N.D. Mazarakis VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model Nature 429 2004 413 417
3. C.-H. Berthold, and M. Rydmark Morphology of normal peripheral axons S.G. Waxman The axon: structure, function, and pathophysiology 1995 Oxford University Press New York 13 48
4. H. Busch, and K. Smetana The nucleolus 1970 Academic Press New York
5. M.J. Chung, and Y.L. Suh Ultrastructural changes of mitochondria in the skeletal muscle of patients with amyotrophic lateral sclerosis Ultrastruct. Pathol. 26 2002 3 7
6. W.A. Day, K. Koishi, and I.S. McLennan Transforming growth factor beta 1 may regulate the stability of mature myelin sheaths Exp. Neurol. 284 2003 857 864
7. B.N. DeSousa, and L.A. Horrocks Development of rat spinal cord I. Weight and length with a method for rapid removal Dev. Neurosci. 2 1979 115 121
8. K.M. Dhandapani, M. Hadman, L. De Sevilla, M.F. Wade, V.B. Mahesh, and D.W. Brann Astrocyte protection of neurons: role of transforming growth factor-beta signaling via a c-Jun-AP-1 protective pathway J. Biol. Chem. 278 2003 43329 43339
9. S.J. Feeney, P.A. McKelvie, L. Austin, M.J. Jean-Francois, R. Kapsa, S.M. Tombs, and E. Byrne Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis Muscle Nerve 24 2001 1510 1519
10. L.R. Fischer, D.G. Culver, P. Tennant, A.A. Davis, M. Wang, A. Castellano-Sanchez, J. Khan, M.A. Polak, and J.D. Glass Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man Exp. Neurol. 185 2004 232 240
11. D. Frey, C. Schneider, L. Xu, J. Borg, W. Spooren, and P. Caroni Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases J. Neurosci. 20 2000 2534 2542
12. Y.H. Gong, A.S. Parsadanian, A. Andreeva, W.D. Snider, and J.L. Elliott Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration J. Neurosci. 20 2000 660 665
13. H.J. Gundersen, P. Bagger, T.F. Bendtsen, S.M. Evans, L. Korbo, N. Marcussen, A. Moller, K. Nielsen, J.R. Nyengaard, B. Pakkenberg, F.B. Sorensen, A. Vesterby, and M.J. West The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis Acta Pathol. Microbiol. Immunol. Scand. 96 1988 857 881
14. M.E. Gurney, H. Pu, A.Y. Chiu, M.C. Dal Canto, C.Y. Polchow, D.D. Alexander, J. Caliendo, A. Hentati, Y.W. Kwon, H.X. Deng, W. Chen, P. Zhai, R.L. Sufit, and T. Siddique Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation Science 264 1994 1772 1775
15. U.I. Heine, J.K. Burmester, K.C. Flanders, D. Danielpour, E.F. Munoz, A.B. Roberts, and M.B. Sporn Localization of transforming growth factor-beta-1 in mitochondria of murine heart and liver Cell Regul. 2 1991 467 477
16. R.A. Ignotz, and J. Massague Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix J. Biol. Chem. 261 1986 4337 4445
17. Y. Jiang, I.S. McLennan, K. Koishi, and I.A. Hendry TGF-beta2 is anterogradely and retrogradely transported in motoneurons and up-regulated after nerve injury Neuroscience 97 2000 735 742
18. Y. Jiang, M. Zhang, K. Koishi, and I.S. McLennan TGF-beta2 attenuates injury-induced death of mature motoneurones J. Neurosci. Res. 62 2000 809 813
19. E.G. Jordan C.A. Cullis The nucleolus vol. 15 1982 Cambridge University Press Cambridge
20. B.K. Kaspar, J. Llado, N. Sherkat, J.D. Rothstein, and F.H. Gage Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model Science 301 2003 839 842
21. A. Kastin, V. Akerstrom, and W. Pan Circulating TGF-beta1 does not cross the intact blood-brain barrier J. Mol. Neurosci. 2003 21
22. P. Klivenyi, M. Kiaei, G. Gardian, N.Y. Calingasan, and M.F. Beal Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis J. Neurochem. 88 2004 576 582
23. J. Kong, and Z. Xu Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1 J. Neurosci. 18 1998 3241 3250
24. F. Lopez-Casillas, J.L. Wrana, and J. Massague Betaglycan presents ligand to the TGF-beta signaling receptor Cell 73 1993 1435 1444
25. M.P. McFadyen, G. Kusek, V.J. Bolivar, and L. Flaherty Differences among eight inbred strains of mice in motor ability and motor learning on a rotorod Genes Brain Behav. 2 2003 214 219
26. I.S. McLennan, and K. Koishi Transforming growth factor-beta-2 (TGF-β2) is associated with mature rat neuromuscular junctions Neurosci. Lett. 177 1994 151 154
27. I.S. McLennan, and K. Koishi Cellular localisation of transforming growth factor-beta 2 and -beta 3 (TGF-β2, TGF-β3) in damaged and regenerating skeletal muscles Dev. Dyn. 208 1997 278 289
28. I.S. McLennan, and K. Koishi The transforming growth factor-betas: multifaceted regulators of the development and maintenance of skeletal muscles, motoneurons and Schwann cells Int. J. Dev. Biol. 46 2002 559 567
29. I.S. McLennan, and J. Taylor-Jeffs The use of sodium lamps to brightly illuminate mouse houses during their dark phases Lab. Anim. 38 2004 1 9
30. I.S. McLennan, K. Koishi, M. Zhang, and N. Murakami The non-synaptic expression of transforming growth factor-beta 2 is neurally regulated and varies between skeletal muscle fibre types Neuroscience 87 1998 845 853
31. I.S. McLennan, Y. Poussart, and K. Koishi Development of skeletal muscles in transforming growth factor-beta 1 (TGF-beta1) null-mutant mice Dev. Dyn. 217 2000 250 256
32. I.S. McLennan, M.W.I. Weible, I.A. Hendry, and K. Koishi Transport of transforming growth factor-beta2 across the blood-brain barrier Neuropharmacology 48 2005 274 282
33. R.W. Oppenheim The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat J. Comp. Neurol. 246 1986 281 286
34. P. Pasinelli, M.E. Belford, N. Lennon, B.J. Bacskai, B.T. Hyman, D. Trotti, and R.H. Brown Jr. Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria Neuron 43 2004 19 30
35. A.E. Postlethwaite, J. Keski-Oja, H.L. Moses, and A.H. Kang Stimulation of the chemotaxic migration of human fibroblasts by transforming growth factor beta J. Exp. Med. 165 1987 251 256
36. J.D. Potts, S. Bassnett, and D.C. Beebe Expression of transforming growth factor beta in the embryonic avian lens coincides with the presence of mitochondria Dev. Dyn. 203 1995 317 323
37. A. Pramatarova, J. Laganiere, J. Roussel, K. Brisebois, and G.A. Rouleau Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment J. Neurosci. 21 2001 3369 3374
38. A.B. Roberts, and M.B. Sporn The transforming growth factor-betas M.B. Sporn A.B. Roberts Handbook of experimental pharmacology Peptide growth factors and their receptors vol. 419-472 1990 Springer-Verlag Berlin 419 472
39. D. Rotzer, M. Roth, M. Lutz, D. Lindemann, W. Sebald, and P. Knaus Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor EMBO J. 20 2001 480 490
40. L.P. Rowland, and N.A. Shneider Amyotrophic lateral sclerosis N. Engl. J. Med. 344 2001 1688 1700
41. T. Sakamoto, Y. Kawazoe, J.S. Shen, Y. Takeda, Y. Arakawa, J. Ogawa, K. Oyanagi, T. Ohashi, K. Watanabe, K. Inoue, Y. Eto, and K. Watabe Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion J. Neurosci. Res. 72 2003 54 64
42. S. Sasaki, H. Warita, K. Abe, and M. Iwata Slow component of axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene Acta Neuropathol. (Berlin) 107 2004 452 460
43. C.F. Stevens The neuron Sci. Am. 241 1979 54 65
44. G. Stoll, M. Schroeter, S. Jander, H. Siebert, A. Wollrath, C. Kleinschnitz, and W. Bruck Lesion-associated expression of transforming growth factor-beta-2 in the rat nervous system: evidence for down-regulating the phagocytic activity of microglia and macrophages Brain Pathol. 14 2004 51 58
45. W. Sun, H. Funakoshi, and T. Nakamura Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS J. Neurosci. 22 2002 6537 6548
46. H. Warita, Y. Itoyama, and K. Abe Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene Brain Res. 819 1999 120 131
47. R. Wright, and H. Nukada Vascular and metabolic factors in the pathogenesis of experimental diabetic neuropathy in mature rats Brain 117 1994 1395 1407