-
1
-
-
67649910494
-
In vivo pharmacodynamic characterization of a novel plectasin antibiotic, NZ2114, in a murine infection model
-
Andes, D., Craig, W., Nielsen, L. A., and Kristensen, H. H. (2009). In vivo pharmacodynamic characterization of a novel plectasin antibiotic, NZ2114, in a murine infection model. Antimicrob. Agents Chemother. 53, 3003-3009.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 3003-3009
-
-
Andes, D.1
Craig, W.2
Nielsen, L.A.3
Kristensen, H.H.4
-
2
-
-
33751532376
-
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system
-
Barlow, P. G., Li, Y. X., Wilkinson, T. S., Bowdish, D. M., Lau, Y. E., Cosseau, C., Haslett, C., Simpson, A. J., Hancock, R. E., and Davidson, D. J. (2006). The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system. J. Leukoc. Biol. 80, 509-520.
-
(2006)
J. Leukoc. Biol.
, vol.80
, pp. 509-520
-
-
Barlow, P.G.1
Li, Y.X.2
Wilkinson, T.S.3
Bowdish, D.M.4
Lau, Y.E.5
Cosseau, C.6
Haslett, C.7
Simpson, A.J.8
Hancock, R.E.9
Davidson, D.J.10
-
3
-
-
30044452344
-
Cationic host defense (antimicrobial) peptides
-
Brown, K. L., and Hancock, R. E. (2006). Cationic host defense (antimicrobial) peptides. Curr. Opin. Immunol. 18, 24-30.
-
(2006)
Curr. Opin. Immunol.
, vol.18
, pp. 24-30
-
-
Brown, K.L.1
Hancock, R.E.2
-
4
-
-
84863331797
-
Cationic host defence peptides: multifaceted role in immune modulation and inflammation
-
Choi, K. Y., Chow, L. N., and Mookherjee, N. (2012). Cationic host defence peptides: multifaceted role in immune modulation and inflammation. J. Innate Immun. 4, 361-370.
-
(2012)
J. Innate Immun.
, vol.4
, pp. 361-370
-
-
Choi, K.Y.1
Chow, L.N.2
Mookherjee, N.3
-
5
-
-
77951271759
-
Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II
-
de Leeuw, E., Li, C. Q., Zeng, P. Y., Li, C., Diepeveen-de Buin, M., Lu, W. Y., Breukink, E., and Lu, W. Y. (2010). Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II. FEBS Lett. 584, 1543-1548.
-
(2010)
FEBS Lett
, vol.584
, pp. 1543-1548
-
-
de Leeuw, E.1
Li, C.Q.2
Zeng, P.Y.3
Li, C.4
Diepeveen-de Buin, M.5
Lu, W.Y.6
Breukink, E.7
Lu, W.Y.8
-
6
-
-
69949086979
-
Potential of immunomodulatory host defense peptides as novel anti-infectives
-
Easton, D. M., Nijnik, A., Mayer, M. L., and Hancock, R. E. (2009). Potential of immunomodulatory host defense peptides as novel anti-infectives. Trends Biotechnol. 27, 582-590.
-
(2009)
Trends Biotechnol
, vol.27
, pp. 582-590
-
-
Easton, D.M.1
Nijnik, A.2
Mayer, M.L.3
Hancock, R.E.4
-
7
-
-
34447560960
-
Toxicity of polymyxins: a systematic review of the evidence from old and recent studies
-
Falagas, M. E., and Kasiakou, S. K. (2006). Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. Crit. Care 10, R27.
-
(2006)
Crit. Care
, vol.10
-
-
Falagas, M.E.1
Kasiakou, S.K.2
-
8
-
-
36749042671
-
Human beta-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2
-
Funderburg, N., Lederman, M. M., Feng, Z., Drage, M. G., Jacllowsky, J., Harding, C. V., Weinberg, A., and Sieg, S. F. (2007). Human beta-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2. Proc. Natl. Acad. Sci. U.S.A. 104, 18631-18635.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 18631-18635
-
-
Funderburg, N.1
Lederman, M.M.2
Feng, Z.3
Drage, M.G.4
Jacllowsky, J.5
Harding, C.V.6
Weinberg, A.7
Sieg, S.F.8
-
9
-
-
0141799911
-
Defensins: antimicrobial peptides of innate immunity
-
Ganz, T. (2003). Defensins: antimicrobial peptides of innate immunity. Nat. Rev. Immunol. 3, 710-720.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 710-720
-
-
Ganz, T.1
-
10
-
-
0032007854
-
Cationic peptides: a new source of antibiotics
-
Hancock, R. E., and Lehrer, R. (1998). Cationic peptides: a new source of antibiotics. Trends Biotechnol. 16, 82-88.
-
(1998)
Trends Biotechnol
, vol.16
, pp. 82-88
-
-
Hancock, R.E.1
Lehrer, R.2
-
11
-
-
33845699790
-
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
-
Hancock, R. E., and Sahl, H. G. (2006). Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 24, 1551-1557.
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 1551-1557
-
-
Hancock, R.E.1
Sahl, H.G.2
-
12
-
-
65349178179
-
Human beta-defensin-3 promotes wound heating in infected diabetic wounds
-
Hirsch, T., Spielmann, M., Zuhaili, B., Fossum, M., Metzig, M., Koehler, T., Steinau, H. U., Yao, F., Onderdonk, A. B., Steinstraesser, L., and Eriksson, E. (2009). Human beta-defensin-3 promotes wound heating in infected diabetic wounds. J. Gene Med. 11, 220-228.
-
(2009)
J. Gene Med.
, vol.11
, pp. 220-228
-
-
Hirsch, T.1
Spielmann, M.2
Zuhaili, B.3
Fossum, M.4
Metzig, M.5
Koehler, T.6
Steinau, H.U.7
Yao, F.8
Onderdonk, A.B.9
Steinstraesser, L.10
Eriksson, E.11
-
13
-
-
67449091655
-
Expression profile of human beta-defensin 3 in oral squamous cell carcinoma
-
Kesting, M. R., Loeffelbein, D. J., Hasler, R. J., Wolff, K. D., Rittig, A., Schulte, M., Hirsch, T., Wagenpfeil, S., Jacobsen, F., and Steinstraesser, L. (2009). Expression profile of human beta-defensin 3 in oral squamous cell carcinoma. Cancer Invest. 27, 575-581.
-
(2009)
Cancer Invest
, vol.27
, pp. 575-581
-
-
Kesting, M.R.1
Loeffelbein, D.J.2
Hasler, R.J.3
Wolff, K.D.4
Rittig, A.5
Schulte, M.6
Hirsch, T.7
Wagenpfeil, S.8
Jacobsen, F.9
Steinstraesser, L.10
-
14
-
-
84155174651
-
Human ss-defensins differently affect proliferation, differentiation, and mineralization of osteoblast-like MG63 cells
-
Kraus, D., Deschner, J., Jäger, A., Wenghoefer, M., Bayer, S., Jepsen, S., Allam, J. P., Novak, N., Meyer, R., and Winter, J. (2012). Human ss-defensins differently affect proliferation, differentiation, and mineralization of osteoblast-like MG63 cells. J. Cell. Physiol. 227, 994-1003.
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 994-1003
-
-
Kraus, D.1
Deschner, J.2
Jäger, A.3
Wenghoefer, M.4
Bayer, S.5
Jepsen, S.6
Allam, J.P.7
Novak, N.8
Meyer, R.9
Winter, J.10
-
15
-
-
4444246692
-
Primate defensins
-
Lehrer, R. I. (2004). Primate defensins. Nat. Rev. Microbiol. 2, 727-738.
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 727-738
-
-
Lehrer, R.I.1
-
16
-
-
56749150574
-
Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream
-
Lipsky, B. A., Holroyd, K. J., and Zasloff, M. (2008). Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream. Clin. Infect. Dis. 47, 1537-1545.
-
(2008)
Clin. Infect. Dis.
, vol.47
, pp. 1537-1545
-
-
Lipsky, B.A.1
Holroyd, K.J.2
Zasloff, M.3
-
17
-
-
6344241043
-
Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4
-
Maemoto, A., Qu, X. Q., Rosengren, K. J., Tanabe, H., Henschen-Edman, A., Craik, D. J., and Ouellette, A. J. (2004). Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4. J. Biol. Chem. 279, 44188-44196.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44188-44196
-
-
Maemoto, A.1
Qu, X.Q.2
Rosengren, K.J.3
Tanabe, H.4
Henschen-Edman, A.5
Craik, D.J.6
Ouellette, A.J.7
-
18
-
-
24644475283
-
Defensins and other antimicrobial peptides at the ocular surface
-
McDermott, A. M. (2004). Defensins and other antimicrobial peptides at the ocular surface. Ocul. Surf. 2, 229-247.
-
(2004)
Ocul. Surf.
, vol.2
, pp. 229-247
-
-
McDermott, A.M.1
-
19
-
-
17044394805
-
Design of host defence peptides for antimicrobial and immunity enhancing activities
-
McPhee, J. B., Scott, M. G., and Hancock, R. E. (2005). Design of host defence peptides for antimicrobial and immunity enhancing activities. Comb. Chem. High Throughput Screen. 8, 257-272.
-
(2005)
Comb. Chem. High Throughput Screen.
, vol.8
, pp. 257-272
-
-
McPhee, J.B.1
Scott, M.G.2
Hancock, R.E.3
-
20
-
-
30044433704
-
Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37
-
Mookherjee, N., Brown, K. L., Bowdish, D. M., Doria, S., Falsafi, R., Hokamp, K., Roche, F. M., Mu, R. X., Doho, G. H., Pistolic, J., Powers, J. P., Bryan, J., Brinkman, F. S., and Hancock, R. E. (2006). Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37. J. Immunol. 176, 2455-2464.
-
(2006)
J. Immunol.
, vol.176
, pp. 2455-2464
-
-
Mookherjee, N.1
Brown, K.L.2
Bowdish, D.M.3
Doria, S.4
Falsafi, R.5
Hokamp, K.6
Roche, F.M.7
Mu, R.X.8
Doho, G.H.9
Pistolic, J.10
Powers, J.P.11
Bryan, J.12
Brinkman, F.S.13
Hancock, R.E.14
-
21
-
-
77951908013
-
Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment
-
Nijnik, A., Madera, L., Ma, S. H., Waldbrook, M., Elliott, M. R., Easton, D. M., Mayer, M. L., Mullaly, S. C., Kindrachuk, J., Jenssen, H., and Hancock, R. E. (2010). Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J. Immunol. 184, 2539-2550.
-
(2010)
J. Immunol.
, vol.184
, pp. 2539-2550
-
-
Nijnik, A.1
Madera, L.2
Ma, S.H.3
Waldbrook, M.4
Elliott, M.R.5
Easton, D.M.6
Mayer, M.L.7
Mullaly, S.C.8
Kindrachuk, J.9
Jenssen, H.10
Hancock, R.E.11
-
22
-
-
0036208192
-
Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway
-
Niyonsaba, F., Iwabuchi, K., Matsuda, H., Ogawa, H., and Nagaoka, I. (2002). Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway. Int. Immunol. 14, 421-426.
-
(2002)
Int. Immunol.
, vol.14
, pp. 421-426
-
-
Niyonsaba, F.1
Iwabuchi, K.2
Matsuda, H.3
Ogawa, H.4
Nagaoka, I.5
-
23
-
-
0035058454
-
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D-2 production from mast cells
-
Niyonsaba, F., Someya, A., Hirata, M., Ogawa, H., and Nagaoka, I. (2001). Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D-2 production from mast cells. Eur. J. Immunol. 31, 1066-1075.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 1066-1075
-
-
Niyonsaba, F.1
Someya, A.2
Hirata, M.3
Ogawa, H.4
Nagaoka, I.5
-
24
-
-
33847040438
-
Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines
-
Niyonsaba, F., Ushio, H., Nakano, N., Ng, W., Sayama, K., Hashimoto, K., Nagaoka, I., Okumura, K., and Ogawa, H. (2007). Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. J. Invest. Dermatol. 127, 594-604.
-
(2007)
J. Invest. Dermatol.
, vol.127
, pp. 594-604
-
-
Niyonsaba, F.1
Ushio, H.2
Nakano, N.3
Ng, W.4
Sayama, K.5
Hashimoto, K.6
Nagaoka, I.7
Okumura, K.8
Ogawa, H.9
-
25
-
-
0031005930
-
A repertoire of novel antibacterial diastereomeric peptides with selective cytolytic activity
-
Oren, Z., Hong, J., and Shai, Y. (1997). A repertoire of novel antibacterial diastereomeric peptides with selective cytolytic activity. J. Biol. Chem. 272, 14643-14649.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14643-14649
-
-
Oren, Z.1
Hong, J.2
Shai, Y.3
-
26
-
-
2342520028
-
The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis
-
Sandgren, S., Wittrup, A., Cheng, F., Jonsson, M., Eklund, E., Busch, S., and Belting, M. (2004). The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis. J. Biol. Chem. 279, 17951-17956.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17951-17956
-
-
Sandgren, S.1
Wittrup, A.2
Cheng, F.3
Jonsson, M.4
Eklund, E.5
Busch, S.6
Belting, M.7
-
27
-
-
50049096434
-
Mode of action of human beta-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge
-
Sass, V., Pag, U., Tossi, A., Bierbaum, G., and Sahl, H. G. (2008). Mode of action of human beta-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge. Int. J. Med. Microbiol. 298, 619-633.
-
(2008)
Int. J. Med. Microbiol.
, vol.298
, pp. 619-633
-
-
Sass, V.1
Pag, U.2
Tossi, A.3
Bierbaum, G.4
Sahl, H.G.5
-
28
-
-
77952693839
-
Human beta-defensin 3 inhibits cell wall biosynthesis in staphylococci
-
Sass, V., Schneider, T., Wilmes, M., Körner, C., Tossi, A., Novikova, N., Shamova, O., and Sahl, H. G. (2010). Human beta-defensin 3 inhibits cell wall biosynthesis in staphylococci. Infect. Immun. 78, 2793-2800.
-
(2010)
Infect. Immun.
, vol.78
, pp. 2793-2800
-
-
Sass, V.1
Schneider, T.2
Wilmes, M.3
Körner, C.4
Tossi, A.5
Novikova, N.6
Shamova, O.7
Sahl, H.G.8
-
29
-
-
77956547991
-
Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II
-
Schmitt, P., Wilmes, M., Pugniere, M., Aumelas, A., Bachere, E., Sahl, H. G., Schneider, T., and Destoumieux-Garzon, D. (2010). Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II. J. Biol. Chem. 285, 29208-29216.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 29208-29216
-
-
Schmitt, P.1
Wilmes, M.2
Pugniere, M.3
Aumelas, A.4
Bachere, E.5
Sahl, H.G.6
Schneider, T.7
Destoumieux-Garzon, D.8
-
30
-
-
23844442574
-
Human defensins
-
Schneider, J. J., Unholzer, A., Schaller, M., Schäfer-Korting, M., and Korting, H. C. (2005). Human defensins. J. Mol. Med. 83, 587-595.
-
(2005)
J. Mol. Med.
, vol.83
, pp. 587-595
-
-
Schneider, J.J.1
Unholzer, A.2
Schaller, M.3
Schäfer-Korting, M.4
Korting, H.C.5
-
31
-
-
77952976637
-
Plectasin, a fungal defensin, targets the bacterial cell wall precursor lipid II
-
Schneider, T., Kruse, T., Wimmer, R., Wiedemann, I., Sass, V., Pag, U., Jansen, A., Nielsen, A. K., Mygind, P. H., Ravents, D. S., Neve, S., Ravn, B., Bonvin, A. M., De Maria, L., Andersen, A. S., Gammelgaard, L. K., Sahl, H. G., and Kristensen, H. H. (2010). Plectasin, a fungal defensin, targets the bacterial cell wall precursor lipid II. Science 328, 1168-1172.
-
(2010)
Science
, vol.328
, pp. 1168-1172
-
-
Schneider, T.1
Kruse, T.2
Wimmer, R.3
Wiedemann, I.4
Sass, V.5
Pag, U.6
Jansen, A.7
Nielsen, A.K.8
Mygind, P.H.9
Ravents, D.S.10
Neve, S.11
Ravn, B.12
Bonvin, A.M.13
De Maria, L.14
Andersen, A.S.15
Gammelgaard, L.K.16
Sahl, H.G.17
Kristensen, H.H.18
-
32
-
-
0036785559
-
The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses
-
Scott, M. G., Davidson, D. J., Gold, M. R., Bowdish, D., and Hancock, R. E. (2002). The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. J. Immunol. 169, 3883-3891.
-
(2002)
J. Immunol.
, vol.169
, pp. 3883-3891
-
-
Scott, M.G.1
Davidson, D.J.2
Gold, M.R.3
Bowdish, D.4
Hancock, R.E.5
-
33
-
-
34147147029
-
An anti-infective peptide that selectively modulates the innate immune response
-
Scott, M. G., Dullaghan, E., Mookherjee, N., Glavas, N., Waldbrook, M., Thompson, A., Wang, A. K., Lee, K., Doria, S., Hamill, P., Yu, J. J., Li, Y. X., Donini, O., Guarna, M. M., Finlay, B. B., North, J. R., and Hancock, R. E. (2007). An anti-infective peptide that selectively modulates the innate immune response. Nat. Biotechnol. 25, 465-472.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 465-472
-
-
Scott, M.G.1
Dullaghan, E.2
Mookherjee, N.3
Glavas, N.4
Waldbrook, M.5
Thompson, A.6
Wang, A.K.7
Lee, K.8
Doria, S.9
Hamill, P.10
Yu, J.J.11
Li, Y.X.12
Donini, O.13
Guarna, M.M.14
Finlay, B.B.15
North, J.R.16
Hancock, R.E.17
-
34
-
-
0036948138
-
Mode of action of membrane active antimicrobial peptides
-
Shai, Y. (2002). Mode of action of membrane active antimicrobial peptides. Biopolymers 66, 236-248.
-
(2002)
Biopolymers
, vol.66
, pp. 236-248
-
-
Shai, Y.1
-
35
-
-
55849130745
-
Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages
-
Soehnlein, O., Kai-Larsen, Y., Frithiof, R., Sorensen, O. E., Kenne, E., Scharffetter-Kochanek, K., Eriksson, E. E., Herwald, H., Agerberth, B., and Lindbom, L. (2008). Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages. J. Clin. Invest. 118, 3491-3502.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3491-3502
-
-
Soehnlein, O.1
Kai-Larsen, Y.2
Frithiof, R.3
Sorensen, O.E.4
Kenne, E.5
Scharffetter-Kochanek, K.6
Eriksson, E.E.7
Herwald, H.8
Agerberth, B.9
Lindbom, L.10
-
36
-
-
47949133231
-
Immunomodulatory properties of antibiotics
-
Tauber, S. C., and Nau, R. (2008). Immunomodulatory properties of antibiotics. Curr. Mol. Pharmacol. 1, 68-79.
-
(2008)
Curr. Mol. Pharmacol.
, vol.1
, pp. 68-79
-
-
Tauber, S.C.1
Nau, R.2
-
37
-
-
0642338937
-
DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae
-
Thevissen, K., Francois, I. E., Takemoto, J. Y., Ferket, K. K., Meert, E. M., and Cammue, B. P. (2003). DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae. FEMS Microbiol. Lett. 226, 169-173.
-
(2003)
FEMS Microbiol. Lett.
, vol.226
, pp. 169-173
-
-
Thevissen, K.1
Francois, I.E.2
Takemoto, J.Y.3
Ferket, K.K.4
Meert, E.M.5
Cammue, B.P.6
-
38
-
-
15844428275
-
Fungal membrane responses induced by plant defensins and thionins
-
Thevissen, K., Ghazi, A., De Samblanx, G. W., Brownlee, C., Osborn, R. W., and Broekaert, W. F. (1996). Fungal membrane responses induced by plant defensins and thionins. J. Biol. Chem. 271, 15018-15025.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15018-15025
-
-
Thevissen, K.1
Ghazi, A.2
De Samblanx, G.W.3
Brownlee, C.4
Osborn, R.W.5
Broekaert, W.F.6
-
39
-
-
84863396190
-
The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans
-
Thevissen, K., Tavares, P. D., Xu, D. M., Blankenship, J., Vandenbosch, D., Idkowiak-Baldys, J., Govaert, G., Bink, A., Rozental, S., de Groot, P. W., Davis, T. R., Kumamoto, C. A., Vargas, G., Nimrichter, L., Coenye, T., Mitchell, A., Roemer, T., Hannun, Y. A., and Cammue, B. P. (2012). The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans. Mol. Microbiol. 84, 166-180.
-
(2012)
Mol. Microbiol.
, vol.84
, pp. 166-180
-
-
Thevissen, K.1
Tavares, P.D.2
Xu, D.M.3
Blankenship, J.4
Vandenbosch, D.5
Idkowiak-Baldys, J.6
Govaert, G.7
Bink, A.8
Rozental, S.9
de Groot, P.W.10
Davis, T.R.11
Kumamoto, C.A.12
Vargas, G.13
Nimrichter, L.14
Coenye, T.15
Mitchell, A.16
Roemer, T.17
Hannun, Y.A.18
Cammue, B.P.19
-
40
-
-
24644495105
-
RDP58 is a novel and potentially effective oral therapy for ulcerative colitis
-
Travis, S., Yap, L. M., Hawkey, C., Warren, B., Lazarov, M., Fong, T., and Tesi, R. J. (2005). RDP58 is a novel and potentially effective oral therapy for ulcerative colitis. Inflamm. Bowel Dis. 11, 713-719.
-
(2005)
Inflamm. Bowel Dis.
, vol.11
, pp. 713-719
-
-
Travis, S.1
Yap, L.M.2
Hawkey, C.3
Warren, B.4
Lazarov, M.5
Fong, T.6
Tesi, R.J.7
-
41
-
-
10744229987
-
A multinational, randomized phase III trial of iseganan HCL oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancy
-
Trotti, A., Garden, A., Warde, P., Symonds, P., Langer, C., Redman, R., Pajak, T. F., Fleming, T. R., Henke, M., Bourhis, J., Rosenthal, D. I., Junor, E., Cmelak, A., Sheehan, F., Pulliam, J., Devitt-Risse, P., Fuchs, H., Chambers, M., O'Sullivan, B., and Ang, K. K. (2004). A multinational, randomized phase III trial of iseganan HCL oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancy. Int. J. Radiat. Oncol. Biol. Phys. 58, 674-681.
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.58
, pp. 674-681
-
-
Trotti, A.1
Garden, A.2
Warde, P.3
Symonds, P.4
Langer, C.5
Redman, R.6
Pajak, T.F.7
Fleming, T.R.8
Henke, M.9
Bourhis, J.10
Rosenthal, D.I.11
Junor, E.12
Cmelak, A.13
Sheehan, F.14
Pulliam, J.15
Devitt-Risse, P.16
Fuchs, H.17
Chambers, M.18
O'Sullivan, B.19
Ang, K.K.20
more..
-
42
-
-
80051523658
-
Modulation of interleukin-1 beta-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts
-
Turner-Brannen, E., Choi, K. Y., Lippert, D. N., Cortens, J. P., Hancock, R. E., El Gabalawy, H., and Mookherjee, N. (2011). Modulation of interleukin-1 beta-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts. Arthritis Res. Ther. 13, R129.
-
(2011)
Arthritis Res. Ther.
, vol.13
-
-
Turner-Brannen, E.1
Choi, K.Y.2
Lippert, D.N.3
Cortens, J.P.4
Hancock, R.E.5
El Gabalawy, H.6
Mookherjee, N.7
-
43
-
-
77956973165
-
Structural studies of a peptide with immune modulating and direct antimicrobial activity
-
Wieczorek, M., Jenssen, H., Kindrachuk, J., Scott, W. R., Elliott, M., Hilpert, K., Cheng, J. T., Hancock, R. E., and Straus, S. K. (2010). Structural studies of a peptide with immune modulating and direct antimicrobial activity. Chem. Biol. 17, 970-980.
-
(2010)
Chem. Biol.
, vol.17
, pp. 970-980
-
-
Wieczorek, M.1
Jenssen, H.2
Kindrachuk, J.3
Scott, W.R.4
Elliott, M.5
Hilpert, K.6
Cheng, J.T.7
Hancock, R.E.8
Straus, S.K.9
-
44
-
-
0042808526
-
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3
-
Wu, Z. B., Hoover, D. M., Yang, D., Boulegue, C., Santamaria, F., Oppenheim, J. J., Lubkowski, J., and Lu, W. Y. (2003). Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3. Proc. Natl. Acad. Sci. U.S.A. 100, 8880-8885.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 8880-8885
-
-
Wu, Z.B.1
Hoover, D.M.2
Yang, D.3
Boulegue, C.4
Santamaria, F.5
Oppenheim, J.J.6
Lubkowski, J.7
Lu, W.Y.8
-
45
-
-
0033844287
-
Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
-
Yang, D., Chen, Q., Chertov, O., and Oppenheim, J. J. (2000). Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J. Leukoc. Biol. 68, 9-14.
-
(2000)
J. Leukoc. Biol.
, vol.68
, pp. 9-14
-
-
Yang, D.1
Chen, Q.2
Chertov, O.3
Oppenheim, J.J.4
-
46
-
-
79960936612
-
Multifunctional cationic host defence peptides and their clinical applications
-
Yeung, A. T., Gellatly, S. L., and Hancock, R. E. (2011). Multifunctional cationic host defence peptides and their clinical applications. Cell. Mol. Life Sci. 68, 2161-2176.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 2161-2176
-
-
Yeung, A.T.1
Gellatly, S.L.2
Hancock, R.E.3
-
47
-
-
0037165196
-
Antimicrobial peptides of multicellular organisms
-
Zasloff, M. (2002). Antimicrobial peptides of multicellular organisms. Nature 415, 389-395.
-
(2002)
Nature
, vol.415
, pp. 389-395
-
-
Zasloff, M.1
-
48
-
-
21444442023
-
Antimicrobial peptide therapeutics for cystic fibrosis
-
Zhang, L. J., Parente, J., Harris, S. A., Woods, D. E., Hancock, R. E., and Fallal, T. J. (2005). Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob. Agents Chemother. 49, 2921-2927
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 2921-2927
-
-
Zhang, L.J.1
Parente, J.2
Harris, S.A.3
Woods, D.E.4
Hancock, R.E.5
Fallal, T.J.6
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