Insight into invertebrate defensin mechanism of action: Oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II

Journal of Biological Chemistry

Volumn 285, Issue 38, 2010, Pages 29208-29216

  Schmitt, Paulina ^a,b   Wilmes, Miriam ^c   Pugnière, Martine ^d   Aumelas, André ^b   Bachère, Evelyne ^a,b   Sahl, Hans Georg ^c   Schneider, Tanja ^c   Destoumieux Garzón, Delphine ^a,b  

^a CNRS   (France)

^b UNIV MONTPELLIER   (France)

^c UNIVERSITY OF BONN   (Germany)

^d University of Montpellier I and II   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BACTERIOLOGY; BIOSYNTHESIS; CHROMATOGRAPHIC ANALYSIS; SURFACE PLASMON RESONANCE; THIN LAYER CHROMATOGRAPHY;

ACTIVE AGENTS; ACTIVITY RESULTS; ANTI-BACTERIAL ACTIVITY; BACTERIAL MEMBRANES; BIOSYNTHESIS PATHWAYS; CELL WALL BIOSYNTHESIS; CELL WALLS; CONSERVED RESIDUES; DEFENSINS; ELECTROSTATIC INTERACTIONS; EXPERIMENTAL DATA; GRAM-POSITIVE BACTERIUM; LETHAL CONCENTRATION; MECHANISM OF ACTION; MEMBRANE INTEGRITY; MOLECULAR DIVERSITY; PEPTIDOGLYCAN PRECURSORS; PEPTIDOGLYCANS; SEQUENCE DIVERSITY; SPECIFIC INHIBITORS; STAPHYLOCOCCUS AUREUS; SURFACE PLASMONS;

BIOCHEMISTRY;

DEFENSIN; LIPID; LIPID II; PENTAPEPTIDE; PEPTIDOGLYCAN; PROTEIN DEFH1; PROTEIN DEFH2; PROTEIN DEFM; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLMURAMYL PENTAPEPTIDE; ANTIINFECTIVE AGENT; MURAMYL-NAC-(PENTAPEPTIDE)PYROPHOSPHORYL-UNDECAPRENOL; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL MEMBRANE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; GLYCOPROTEIN SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; NONHUMAN; OYSTER; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN SYNTHESIS INHIBITION; STAPHYLOCOCCUS AUREUS; STATIC ELECTRICITY; SURFACE PLASMON RESONANCE; THIN LAYER CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; CELL MEMBRANE; CELL WALL; CHEMISTRY; DRUG EFFECTS; GENETICS; INVERTEBRATE; METABOLISM; MICROBIAL SENSITIVITY TEST; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BACTERIA (MICROORGANISMS); INVERTEBRATA; OSTREIDAE; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL MEMBRANE; CELL WALL; CHROMATOGRAPHY, THIN LAYER; DEFENSINS; GRAM-POSITIVE BACTERIA; INVERTEBRATES; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; OSTREIDAE; PEPTIDOGLYCAN; STAPHYLOCOCCUS AUREUS; SURFACE PLASMON RESONANCE; URIDINE DIPHOSPHATE N-ACETYLMURAMIC ACID;

EID: 77956547991     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.143388     Document Type: Article

References (45)

1. Shai, Y. (2002) Biopolymers 66, 236-248
2. Bulet, P., Stöcklin, R., and Menin, L. (2004) Immunol. Rev. 198, 169-184
3. Brogden, K. A. (2005) Nat. Rev. Microbiol. 3, 238-250
4. Boulanger, N., Lowenberger, C., Volf, P., Ursic, R., Sigutova, L., Sabatier, L., Svobodova, M., Beverley, S. M., Späth, G., Brun, R., Pesson, B., and Bulet, P. (2004) Infect. Immun. 72, 7140-7146
5. Bulet, P., and Stöcklin, R. (2005) Protein Pept. Lett. 12, 3-11
6. Yang, Y. S., Mitta, G., Chavanieu, A., Calas, B., Sanchez, J. F., Roch, P., and Aumelas, A. (2000) Biochemistry 39, 14436-14447
7. Gueguen, Y., Herpin, A., Aumelas, A., Garnier, J., Fievet, J., Escoubas, J. M., Bulet, P., Gonzalez, M., Lelong, C., Favrel, P., and Bachère, E. (2006) J. Biol. Chem. 281, 313-323
8. Mygind, P. H., Fischer, R. L., Schnorr, K. M., Hansen, M. T., Sönksen, C. P., Ludvigsen, S., Raventós, D., Buskov, S., Christensen, B., De Maria, L., Taboureau, O., Yaver, D., Elvig-Jørgensen, S. G., Sørensen, M. V., Christensen, B. E., Kjaerulff, S., Frimodt-Moller, N., Lehrer, R. I., Zasloff, M., and Kristensen, H. H. (2005) Nature 437, 975-980
9. Imler, J. L., and Bulet, P. (2005) Chem. Immunol. Allergy 86, 1-21
10. Martin, E., Ganz, T., and Lehrer, R. I. (1995) J. Leukocyte Biol. 58, 128-136
11. Yeaman, M. R., and Yount, N. Y. (2003) Pharmacol. Rev. 55, 27-55
12. Hadjicharalambous, C., Sheynis, T., Jelinek, R., Shanahan, M. T., Ouellette, A. J., and Gizeli, E. (2008) Biochemistry 47, 12626-12634
13. Sugiarto, H., and Yu, P. L. (2007) FEMS Microbiol. Lett. 270, 195-200
14. Nakajima, Y., Ishibashi, J., Yukuhiro, F., Asaoka, A., Taylor, D., and Yamakawa, M. (2003) Biochim. Biophys. Acta 1624, 125-130
15. Cociancich, S., Ghazi, A., Hetru, C., Hoffmann, J. A., and Letellier, L. (1993) J. Biol. Chem. 268, 19239-19245
16. Sahl, H. G., Pag, U., Bonness, S., Wagner, S., Antcheva, N., and Tossi, A. (2005) J. Leukocyte Biol. 77, 466-475
17. Destoumieux-Garzón, D., Thomas, X., Santamaria, M., Goulard, C., Barthélémy, M., Boscher, B., Bessin, Y., Molle, G., Pons, A. M., Letellier, L., Peduzzi, J., and Rebuffat, S. (2003) Mol. Microbiol. 49, 1031-1041
18. Hale, J. D., and Hancock, R. E. (2007) Expert Rev. Anti Infect. Ther. 5, 951-959
19. Thevissen, K., Warnecke, D. C., François, I. E., Leipelt, M., Heinz, E., Ott, C., Zähringer, U., Thomma, B. P., Ferket, K. K., and Cammue, B. P. (2004) J. Biol. Chem. 279, 3900-3905
20. Schneider, T., Kruse, T., Wimmer, R., Wiedemann, I., Sass, V., Pag, U., Jansen, A., Nielsen, A. K., Mygind, P. H., Raventós, D. S., Neve, S., Ravn, B., Bonvin, A. M., De Maria, L., Andersen, A. S., Gammelgaard, L. K., Sahl, H. G., and Kristensen, H. H. (2010) Science 328, 1168-1172
21. Leeuw, E. L., Zeng, P., Li, C., Buin, M. D., Lu, W. Y., Breukink, E., and Lu, W. (2010) FEBS Lett. 584, 1543-1548
22. Sass, V., Schneider, T., Wilmes, M., Körner, C., Tossi, A., Novikova, N., Shamova, O., and Sahl, H. G. (2010) Infect. Immun. 78, 2793-2800
23. Gonzalez, M., Gueguen, Y., Desserre, G., de Lorgeril, J., Romestand, B., and Bachère, E. (2007) Dev. Comp. Immunol. 31, 332-339
24. Schmitt, P., Gueguen, Y., Desmarais, E., Bachère, E., and de Lorgeril, J. (2010) BMC Evol. Biol. 10, 23
25. Hetru, C., and Bulet, P. (1997) Methods Mol. Biol. 78, 35-49
26. Saulnier, D., Avarre, J. C., Le Moullac, G., Ansquer, D., Levy, P., and Vonau, V. (2000) Dis. Aquat. Organ 40, 109-115
27. Dai, D., and Ishiguro, E. E. (1988) J. Bacteriol. 170, 2197-2201
28. Schneider, T., Senn, M. M., Berger-Bächi, B., Tossi, A., Sahl, H. G., and Wiedemann, I. (2004) Mol. Microbiol. 53, 675-685
29. Kohlrausch, U., and Höltje, J. V. (1991) FEMS Microbiol. Lett. 62, 253-257
30. Rayne, F., Debaisieux, S., Yezid, H., Lin, Y. L., Mettling, C., Konate, K., Chazal, N., Arold, S. T., Pugnière, M., Sanchez, F., Bonhoure, A., Briant, L., Loret, E., Roy, C., and Beaumelle, B. (2010) EMBO J. 29, 1348-1362
31. Piotto, M., Saudek, V., and Sklenár, V. (1992) J. Biomol. NMR 2, 661-665
32. van Heijenoort, J. (2001) Glycobiology 11, 25R-36R
33. Doherty, T., Waring, A. J., and Hong, M. (2006) Biochim. Biophys. Acta 1758, 1285-1291
34. Schneider, T., and Sahl, H. G. (2010) Curr. Opin. Investig. Drugs 11, 157-164
35. Wiedemann, I., Breukink, E., van Kraaij, C., Kuipers, O. P., Bierbaum, G., de Kruijff, B., and Sahl, H. G. (2001) J. Biol. Chem. 276, 1772-1779
36. Schneider, T., Gries, K., Josten, M., Wiedemann, I., Pelzer, S., Labischinski, H., and Sahl, H. G. (2009) Antimicrob. Agents Chemother. 53, 1610-1618
37. Yang, Y., Boze, H., Chemardin, P., Padilla, A., Moulin, G., Tassanakajon, A., Pugnière, M., Roquet, F., Destoumieux-Garzón, D., Gueguen, Y., Bachère, E., and Aumelas, A. (2009) Biopolymers 91, 207-220
38. Duperthuy, M., Binesse, J., Le Roux, F., Romestand, B., Caro, A., Got, P., Givaudan, A., Mazel, D., Bachère, E., and Destoumieux-Garzón, D. (2010) Environ. Microbiol. 12, 951-963
39. García, J. R., Jaumann, F., Schulz, S., Krause, A., Rodríguez-Jiménez, J., Forssmann, U., Adermann, K., Klüver, E., Vogelmeier, C., Becker, D., Hedrich, R., Forssmann, W. G., and Bals, R. (2001) Cell Tissue Res. 306, 257-264
40. Selsted, M. E., and Ouellette, A. J. (2005) Nat. Immunol. 6, 551-557
41. Morgera, F., Antcheva, N., Pacor, S., Quaroni, L., Berti, F., Vaccari, L., and Tossi, A. (2008) J. Pept. Sci. 14, 518-523
42. Lamberty, M., Ades, S., Uttenweiler-Joseph, S., Brookhart, G., Bushey, D., Hoffmann, J. A., and Bulet, P. (1999) J. Biol. Chem. 274, 9320-9326
43. Otvos, L., Jr. (2000) J. Pept. Sci. 6, 497-511
44. Froy, O., and Gurevitz, M. (2003) Trends Genet. 19, 684-687
45. Fay, J. C., and Wu, C. I. (2003) Annu. Rev. Genomics Hum. Genet. 4, 213-235