Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 15, 2003, Pages 8880-8885

  Wu, Zhibin ^a   Hoover, David M ^b   Yang, De ^b   Boulègue, Cyril ^a   Santamaria, Fanny ^a   Oppenheim, Joost J ^b   Lubkowski, Jacek ^b   Lu, Wuyuan ^a  

^a INSTITUTE OF HUMAN VIROLOGY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBUTYRIC ACID; BETA DEFENSIN; BETA DEFENSIN 3; CHEMOKINE RECEPTOR CCR6; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; CELLULAR IMMUNITY; CHEMOTAXIS; CONTROLLED STUDY; DENDRITIC CELL; DISULFIDE BOND; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOMODULATION; MONOCYTE; OXIDATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE; RECEPTOR BINDING; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BETA-DEFENSINS; CELL LINE; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; CYSTEINE; DISULFIDES; DRUG DESIGN; ESCHERICHIA COLI; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; PROTEIN FOLDING; SEQUENCE HOMOLOGY, AMINO ACID;

ESCHERICHIA COLI; STAPHYLOCOCCUS PHAGE 3A;

EID: 0042808526     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1533186100     Document Type: Article

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