A simple eccentric stirred tank mini-bioreactor: Mixing characterization and mammalian cell culture experiments

Biotechnology and Bioengineering

Volumn 110, Issue 4, 2013, Pages 1106-1118

  Bulnes Abundis, David ^a   Carrillo Cocom, Leydi M ^a   Aráiz Hernández, Diana ^a   García Ulloa, Alfonso ^a   Granados Pastor, Marisa ^a   Sánchez Arreola, Pamela B ^a   Murugappan, Gayathree ^a   Alvarez, Mario M ^a  

^a SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

Author keywords

Biotechnology; Eccentric; Mammalian cell culture; Mini bioreactor; Mixing; Stirred tank

Indexed keywords

CELL DENSITY; CELL MODEL; CHINESE HAMSTER OVARY CELLS; CULTURE BOTTLES; CULTURE PLATES; ECCENTRIC; ERLENMEYER FLASKS; GOOD MIXING; HEMATOPOIETIC STEM CELLS; INDUSTRIAL PRACTICES; LASER INDUCED FLUORESCENCE; MAMMALIAN CELL CULTURE; MINI-BIOREACTOR; MIXING PERFORMANCE; OPERATIONAL CONDITIONS; PETRI DISH; SCREENING APPLICATION; SCREENING PROTOCOL; SPECIFIC GROWTH RATE; STIRRED TANK; STIRRED TANK BIOREACTORS;

BIOCONVERSION; BIOTECHNOLOGY; BOTTLES; CELL CULTURE; COMPUTATIONAL FLUID DYNAMICS; EXPERIMENTS; MIXING; TANKS (CONTAINERS);

BIOREACTORS;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DENSITY; CELL GROWTH; CELL VIABILITY; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; FEMALE; GEOMETRY; GROWTH RATE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PERFORMANCE; SCALE UP; SHEAR STRESS; SIMULATION; STIRRED REACTOR; STIRRED TANK MINI BIOREACTOR; TIME SERIES ANALYSIS;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; FLUORESCENCE; HUMANS; STRESS, MECHANICAL;

CRICETULUS GRISEUS; MAMMALIA;

EID: 84874197083     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24780     Document Type: Article

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