-
1
-
-
0024593072
-
Characterization of human microsomal cytochrome P-450 enzymes
-
Guengerich, F.P. Characterization of human microsomal cytochrome P-450 enzymes. Annu. Rev. Pharmacol. Toxicol. 29, 241-264 (1989
-
(1989)
Annu. Rev. Pharmacol. Toxicol
, vol.29
, pp. 241-264
-
-
Guengerich, F.P.1
-
2
-
-
77649216536
-
Membrane transporters in drug development
-
International Transporter Consortium. et al.
-
International Transporter Consortium et al. Membrane transporters in drug development. Nat. Rev. Drug Discov. 9, 215-236 (2010
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, pp. 215-236
-
-
-
3
-
-
0032924934
-
Cytochrome P-450 3A4: Regulation and role in drug metabolism
-
Guengerich, F.P. Cytochrome P-450 3A4: regulation and role in drug metabolism. Annu. Rev. Pharmacol. Toxicol. 39, 1-17 (1999
-
(1999)
Annu. Rev. Pharmacol. Toxicol
, vol.39
, pp. 1-17
-
-
Guengerich, F.P.1
-
4
-
-
33645809139
-
The human intestinal cytochrome P450 "pie"
-
Paine, M.F., Hart, H.L., Ludington, S.S., Haining, R.L., Rettie, A.E. & Zeldin, D.C. The human intestinal cytochrome P450 "pie". Drug Metab. Dispos. 34, 880-886 (2006
-
(2006)
Drug Metab. Dispos
, vol.34
, pp. 880-886
-
-
Paine, M.F.1
Hart, H.L.2
Ludington, S.S.3
Haining, R.L.4
Rettie, A.E.5
Zeldin, D.C.6
-
5
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada, T., Yamazaki, H., Mimura, M., Inui, Y. & Guengerich, F.P. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270, 414-423 (1994
-
(1994)
J. Pharmacol. Exp. Ther
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
6
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
-
Wacher, V.J., Wu, C.Y. & Benet, L.Z. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy. Mol. Carcinog. 13, 129-134 (1995
-
(1995)
Mol. Carcinog
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.Y.2
Benet, L.Z.3
-
7
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut, F., Tsuruo, T., Hamada, H., Gottesman, M.M., Pastan, I. & Willingham, M.C. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. U.S.A. 84, 7735-7738 (1987
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
8
-
-
0040368659
-
Identification of a novel gene family encoding human liverspecific organic anion transporter LST-1
-
Abe, T. et al. Identification of a novel gene family encoding human liverspecific organic anion transporter LST-1. J. Biol. Chem. 274, 17159-17163 (1999
-
(1999)
J. Biol. Chem
, vol.274
, pp. 17159-17163
-
-
Abe, T.1
-
9
-
-
0033601257
-
A novel human hepatic organic anion transporting polypeptide (OATP2) Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
-
Hsiang, B. et al. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J. Biol. Chem. 274, 37161-37168 (1999
-
(1999)
J. Biol. Chem
, vol.274
, pp. 37161-37168
-
-
Hsiang, B.1
-
10
-
-
33646205286
-
Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril
-
Maeda, K. et al. Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril. Clin. Pharmacol. Ther. 79, 427-439 (2006
-
(2006)
Clin. Pharmacol. Ther
, vol.79
, pp. 427-439
-
-
Maeda, K.1
-
11
-
-
33645816996
-
OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker
-
Nakagomi-Hagihara, R. et al. OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker. Drug Metab. Dispos. 34, 862-869 (2006
-
(2006)
Drug Metab. Dispos
, vol.34
, pp. 862-869
-
-
Nakagomi-Hagihara, R.1
-
12
-
-
33646536542
-
Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics
-
Ho, R.H. et al. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology 130,1793-1806 (2006
-
(2006)
Gastroenterology
, vol.130
, pp. 1793-1806
-
-
Ho, R.H.1
-
13
-
-
0036089341
-
Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
-
Lin, Y.S. et al. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol. Pharmacol. 62, 162-172 (2002
-
(2002)
Mol. Pharmacol
, vol.62
, pp. 162-172
-
-
Lin, Y.S.1
-
14
-
-
12644272784
-
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine
-
Lown, K.S. et al. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine. Clin. Pharmacol. Ther. 62, 248-260 (1997
-
(1997)
Clin. Pharmacol. Ther
, vol.62
, pp. 248-260
-
-
Lown, K.S.1
-
15
-
-
0142010611
-
P-glycoprotein increases from proximal to distal regions of human small intestine
-
Mouly, S. & Paine, M.F. P-glycoprotein increases from proximal to distal regions of human small intestine. Pharm. Res. 20, 1595-1599 (2003
-
(2003)
Pharm. Res
, vol.20
, pp. 1595-1599
-
-
Mouly, S.1
Paine, M.F.2
-
16
-
-
0031445547
-
Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism
-
Paine, M.F. et al. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. J. Pharmacol. Exp. Ther. 283, 1552-1562 (1997
-
(1997)
J. Pharmacol. Exp. Ther
, vol.283
, pp. 1552-1562
-
-
Paine, M.F.1
-
17
-
-
0029616617
-
Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms
-
Schuetz, E.G., Furuya, K.N. & Schuetz, J.D. Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms. J. Pharmacol. Exp. Ther. 275, 1011-1018 (1995
-
(1995)
J. Pharmacol. Exp. Ther
, vol.275
, pp. 1011-1018
-
-
Schuetz, E.G.1
Furuya, K.N.2
Schuetz, J.D.3
-
18
-
-
1542376174
-
Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: A comparative analysis in paired tissue specimens
-
von Richter, O., Burk, O., Fromm, M.F., Thon, K.P., Eichelbaum, M. & Kivistö, K.T. Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: A comparative analysis in paired tissue specimens. Clin. Pharmacol. Ther. 75, 172-183 (2004
-
(2004)
Clin. Pharmacol. Ther
, vol.75
, pp. 172-183
-
-
Von Richter, O.1
Burk, O.2
Fromm, M.F.3
Thon, K.P.4
Eichelbaum, M.5
Kivistö, K.T.6
-
19
-
-
0036223831
-
Summary of information on human CYP enzymes: Human P450 metabolism data
-
Rendic, S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab. Rev. 34, 83-448 (2002
-
(2002)
Drug Metab. Rev
, vol.34
, pp. 83-448
-
-
Rendic, S.1
-
20
-
-
84865106858
-
Immunological response as a source to variability in drug metabolism and transport
-
Christensen, H. & Hermann, M. Immunological response as a source to variability in drug metabolism and transport. Front. Pharmacol. 3, 8 (2012
-
(2012)
Front. Pharmacol
, vol.3
, pp. 8
-
-
Christensen, H.1
Hermann, M.2
-
21
-
-
0034724324
-
Functional polymorphisms of the human multidrugresistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S. et al. Functional polymorphisms of the human multidrugresistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. U.S.A. 97, 3473-3478 (2000
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
-
22
-
-
35448946484
-
SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers
-
Ieiri, I. et al. SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers. Clin. Pharmacol. Ther. 82, 541-547 (2007
-
(2007)
Clin. Pharmacol. Ther
, vol.82
, pp. 541-547
-
-
Ieiri, I.1
-
23
-
-
3242808852
-
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1
-
Niemi, M. et al. High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1). Pharmacogenetics 14, 429-440 (2004
-
(2004)
Pharmacogenetics
, vol.14
, pp. 429-440
-
-
Niemi, M.1
-
24
-
-
33646911616
-
Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes
-
Hedman, M. et al. Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes. Br. J. Clin. Pharmacol. 61, 706-715 (2006
-
(2006)
Br. J. Clin. Pharmacol
, vol.61
, pp. 706-715
-
-
Hedman, M.1
-
25
-
-
36148953896
-
Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin
-
Pasanen, M.K., Fredrikson, H., Neuvonen, P.J. & Niemi, M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Clin. Pharmacol. Ther. 82, 726-733 (2007
-
(2007)
Clin. Pharmacol. Ther
, vol.82
, pp. 726-733
-
-
Pasanen, M.K.1
Fredrikson, H.2
Neuvonen, P.J.3
Niemi, M.4
-
26
-
-
22544454498
-
Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1.5, SLCO1B1.15 and SLCO1B1.15+C1007G, by using transient expression systems of HeLa and HEK293 cells
-
Kameyama, Y., Yamashita, K., Kobayashi, K., Hosokawa, M. & Chiba, K. Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1.5, SLCO1B1.15 and SLCO1B1.15+C1007G, by using transient expression systems of HeLa and HEK293 cells. Pharmacogenet. Genomics 15, 513-522 (2005
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 513-522
-
-
Kameyama, Y.1
Yamashita, K.2
Kobayashi, K.3
Hosokawa, M.4
Chiba, K.5
-
27
-
-
0031847115
-
Effect of itraconazole on the pharmacokinetics of atorvastatin
-
Kantola, T., Kivistö, K.T. & Neuvonen, P.J. Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin. Pharmacol. Ther. 64, 58-65 (1998
-
(1998)
Clin. Pharmacol. Ther
, vol.64
, pp. 58-65
-
-
Kantola, T.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
28
-
-
0027434229
-
The interconversion kinetics, equilibrium, and solubilities of the lactone and hydroxyacid forms of the HMG-CoA reductase inhibitor, CI-981
-
Kearney, A.S., Crawford, L.F., Mehta, S.C. & Radebaugh, G.W. The interconversion kinetics, equilibrium, and solubilities of the lactone and hydroxyacid forms of the HMG-CoA reductase inhibitor, CI-981. Pharm. Res. 10, 1461-1465 (1993
-
(1993)
Pharm. Res
, vol.10
, pp. 1461-1465
-
-
Kearney, A.S.1
Crawford, L.F.2
Mehta, S.C.3
Radebaugh, G.W.4
-
29
-
-
0242383181
-
Clinical pharmacokinetics of atorvastatin
-
Lennernäs, H. Clinical pharmacokinetics of atorvastatin. Clin. Pharmacokinet. 42, 1141-1160 (2003
-
(2003)
Clin. Pharmacokinet
, vol.42
, pp. 1141-1160
-
-
Lennernäs, H.1
-
30
-
-
0034059327
-
Atorvastatin transport in the Caco-2 cell model: Contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter
-
Wu, X., Whitfield, L.R. & Stewart, B.H. Atorvastatin transport in the Caco-2 cell model: Contributions of P-glycoprotein and the proton- monocarboxylic acid co-transporter. Pharm. Res. 17, 209-215 (2000
-
(2000)
Pharm. Res
, vol.17
, pp. 209-215
-
-
Wu, X.1
Whitfield, L.R.2
Stewart, B.H.3
-
31
-
-
4744370480
-
Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients
-
Hermann, M., Asberg, A., Christensen, H., Holdaas, H., Hartmann, A. & Reubsaet, J.L. Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients. Clin. Pharmacol. Ther. 76, 388-391 (2004
-
(2004)
Clin. Pharmacol. Ther
, vol.76
, pp. 388-391
-
-
Hermann, M.1
Asberg, A.2
Christensen, H.3
Holdaas, H.4
Hartmann, A.5
Reubsaet, J.L.6
-
32
-
-
0242645646
-
Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
-
Lilja, J.J., Kivistö, K.T. & Neuvonen, P.J. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin. Pharmacol. Ther. 66, 118-127 (1999
-
(1999)
Clin. Pharmacol. Ther
, vol.66
, pp. 118-127
-
-
Lilja, J.J.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
33
-
-
77955994141
-
Cyclosporine A but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin
-
Amundsen, R., Christensen, H., Zabihyan, B. & Asberg, A. Cyclosporine A, but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin. Drug Metab. Dispos. 38, 1499-1504 (2010
-
(2010)
Drug Metab. Dispos
, vol.38
, pp. 1499-1504
-
-
Amundsen, R.1
Christensen, H.2
Zabihyan, B.3
Asberg, A.4
-
34
-
-
15344341734
-
Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1
-
Chen, C. et al. Differential interaction of 3-hydroxy-3-methylglutaryl- coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Drug Metab. Dispos. 33, 537-546 (2005
-
(2005)
Drug Metab. Dispos
, vol.33
, pp. 537-546
-
-
Chen, C.1
-
35
-
-
0033783036
-
Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin
-
Jacobsen, W. et al. Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin. Drug Metab. Dispos. 28, 1369-1378 (2000
-
(2000)
Drug Metab. Dispos
, vol.28
, pp. 1369-1378
-
-
Jacobsen, W.1
-
36
-
-
0035929574
-
Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
-
Tirona, R.G., Leake, B.F., Merino, G. & Kim, R.B. Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J. Biol. Chem. 276, 35669-35675 (2001
-
(2001)
J. Biol. Chem
, vol.276
, pp. 35669-35675
-
-
Tirona, R.G.1
Leake, B.F.2
Merino, G.3
Kim, R.B.4
-
37
-
-
41349113141
-
Statin induced myotoxicity: The lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro
-
Skottheim, I.B., Gedde-Dahl, A., Hejazifar, S., Hoel, K. & Asberg, A. Statin induced myotoxicity: The lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro. Eur. J. Pharm. Sci. 33, 317-325 (2008
-
(2008)
Eur. J. Pharm. Sci
, vol.33
, pp. 317-325
-
-
Skottheim, I.B.1
Gedde-Dahl, A.2
Hejazifar, S.3
Hoel, K.4
Asberg, A.5
-
38
-
-
0034471041
-
-
Obesity: Preventing and managing the global epidemic Report of a WHO consultation 1-253
-
Obesity: Preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ. Tech. Rep. Ser. 894, i-xii, 1-253 (2000
-
(2000)
World Health Organ. Tech. Rep. ser
, vol.894
, pp. 1-12
-
-
-
39
-
-
37249012876
-
Obesity geneticrfeti molecular, and environmental aspects
-
Barness, L.A., Opitz, J.M. & Gilbert-Barness, E. Obesity: genetic, molecular, and environmental aspects. Am. J. Med. Genet. A 143A, 3016-3034 (2007
-
(2007)
Am. J. Med. Genet. A.
, vol.143
, pp. 3016-3034
-
-
Barness, L.A.1
Opitz, J.M.2
Gilbert-Barness, E.3
-
40
-
-
0034975420
-
Hepatic cytochrome P450 regulation in disease states
-
Cheng, P.Y. & Morgan, E.T. Hepatic cytochrome P450 regulation in disease states. Curr. Drug Metab. 2, 165-183 (2001
-
(2001)
Curr. Drug Metab
, vol.2
, pp. 165-183
-
-
Cheng, P.Y.1
Morgan, E.T.2
-
41
-
-
0021192084
-
Effect of age, gender, and obesity on midazolam kinetics
-
Greenblatt, D.J., Abernethy, D.R., Locniskar, A., Harmatz, J.S., Limjuco, R.A. & Shader, R.I. Effect of age, gender, and obesity on midazolam kinetics. Anesthesiology 61, 27-35 (1984
-
(1984)
Anesthesiology
, vol.61
, pp. 27-35
-
-
Greenblatt, D.J.1
Abernethy, D.R.2
Locniskar, A.3
Harmatz, J.S.4
Limjuco, R.A.5
Shader, R.I.6
-
42
-
-
34247352929
-
Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine
-
Berggren, S. et al. Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine. Mol. Pharm. 4, 252-257 (2007
-
(2007)
Mol. Pharm
, vol.4
, pp. 252-257
-
-
Berggren, S.1
-
43
-
-
33947231735
-
Expression of cytochromes P450 3A and P-glycoprotein in human large intestine in paired tumour and normal samples
-
Canaparo, R. et al. Expression of cytochromes P450 3A and P-glycoprotein in human large intestine in paired tumour and normal samples. Basic Clin. Pharmacol. Toxicol. 100, 240-248 (2007
-
(2007)
Basic Clin. Pharmacol. Toxicol
, vol.100
, pp. 240-248
-
-
Canaparo, R.1
-
44
-
-
77957735036
-
Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass
-
Bruyere, A. et al. Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass. Mol. Pharm. 7, 1596-1607 (2010
-
(2010)
Mol. Pharm
, vol.7
, pp. 1596-1607
-
-
Bruyere, A.1
-
45
-
-
0025344378
-
Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
-
de Waziers, I., Cugnenc, P.H., Yang, C.S., Leroux, J.P. & Beaune, P.H. Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. J. Pharmacol. Exp. Ther. 253, 387-394 (1990
-
(1990)
J. Pharmacol. Exp. Ther
, vol.253
, pp. 387-394
-
-
De Waziers, I.1
Cugnenc, P.H.2
Yang, C.S.3
Leroux, J.P.4
Beaune, P.H.5
-
46
-
-
0028063131
-
CYP3A gene expression in human gut epithelium
-
Kolars, J.C. et al. CYP3A gene expression in human gut epithelium. Pharmacogenetics 4, 247-259 (1994
-
(1994)
Pharmacogenetics
, vol.4
, pp. 247-259
-
-
Kolars, J.C.1
-
47
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254 (1976
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
48
-
-
34249892467
-
Real-time PCR determination of IMPDH1 and IMPDH2 expression in blood cells
-
Bremer, S., Rootwelt, H. & Bergan, S. Real-time PCR determination of IMPDH1 and IMPDH2 expression in blood cells. Clin. Chem. 53, 1023-1029 (2007
-
(2007)
Clin. Chem
, vol.53
, pp. 1023-1029
-
-
Bremer, S.1
Rootwelt, H.2
Bergan, S.3
-
49
-
-
80054002189
-
OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture
-
Ulvestad, M., Björquist, P., Molden, E., Asberg, A. & Andersson, T.B. OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture. Biochem. Pharmacol. 82, 1219-1226 (2011
-
(2011)
Biochem. Pharmacol
, vol.82
, pp. 1219-1226
-
-
Ulvestad, M.1
Björquist, P.2
Molden, E.3
Asberg, A.4
Andersson, T.B.5
-
50
-
-
79851476433
-
Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: A simulation assessment using the "advanced dissolution, absorption, metabolism (adam)" model
-
Darwich, A.S., Neuhoff, S., Jamei, M. & Rostami-Hodjegan, A. Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: A simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model. Curr. Drug Metab. 11, 716-729 (2010
-
(2010)
Curr. Drug Metab
, vol.11
, pp. 716-729
-
-
Darwich, A.S.1
Neuhoff, S.2
Jamei, M.3
Rostami-Hodjegan, A.4
|