Dietary composition regulates Drosophila mobility and cardiac physiology

Journal of Experimental Biology

Volumn 216, Issue 5, 2013, Pages 859-868

  Bazzell, Brian ^a   Ginzberg, Sara ^a   Healy, Lindsey ^a   Wessells, R J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Diet; Drosophila; Exercise

Indexed keywords

ANIMAL; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CALORIC INTAKE; CHEMISTRY; DIET; DROSOPHILA MELANOGASTER; FEEDING BEHAVIOR; FLYING; GENETICS; HEART; HEART MUSCLE; LIPID METABOLISM; MALE; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SUGAR INTAKE; YEAST;

ANIMALS; AUTOPHAGY; DIET; DIETARY SUCROSE; DROSOPHILA MELANOGASTER; ENERGY INTAKE; FEEDING BEHAVIOR; FLIGHT, ANIMAL; HEART; LIPID METABOLISM; MALE; MODELS, ANIMAL; MYOCARDIUM; STRESS, PHYSIOLOGICAL; YEASTS;

EID: 84874187151     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.078758     Document Type: Article

References (51)

1. Bartke, A., Peluso, M. R., Moretz, N., Wright, C., Bonkowski, M., Winters, T. A., Shanahan, M. F., Kopchick, J. J. and Banz, W. J. (2004). Effects of soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, longlived and short-lived mice. Horm. Metab. Res. 36, 550-558.
2. Bhandari, P., Jones, M. A., Martin, I. and Grotewiel, M. S. (2007). Dietary restriction alters demographic but not behavioral aging in Drosophila. Aging Cell 6, 631-637.
3. Birse, R. T., Choi, J., Reardon, K., Rodriguez, J., Graham, S., Diop, S., Ocorr, K., Bodmer, R. and Oldham, S. (2010). High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell Metab. 12, 533-544.
4. Bishop, N. A. and Guarente, L. (2007). Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat. Rev. Genet. 8, 835-844.
5. Bjedov, I., Toivonen, J. M., Kerr, F., Slack, C., Jacobson, J., Foley, A. and Partridge, L. (2010). Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab. 11, 35-46.
6. Booth, F. W. and Thomason, D. B. (1991). Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models. Physiol. Rev. 71, 541-585.
7. Bouchard, C., Blair, S. N., Church, T. S., Earnest, C. P., Hagberg, J. M., Häkkinen, K., Jenkins, N. T., Karavirta, L., Kraus, W. E., Leon, A. S. et al. (2012). Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS ONE 7, e37887.
8. Catterson, J. H., Knowles-Barley, S., James, K., Heck, M. M. S., Harmar, A. J. and Hartley, P. S. (2010). Dietary modulation of Drosophila sleep-wake behaviour. PLoS ONE 5, e12062.
9. Chandler, J. M. and Hadley, E. C. (1996). Exercise to improve physiologic and functional performance in old age. Clin. Geriatr. Med. 12, 761-784.
10. Chudyk, A. and Petrella, R. J. (2011). Effects of exercise on cardiovascular risk factors in type 2 diabetes: a meta-analysis. Diabetes Care 34, 1228-1237.
11. Demontis, F. and Perrimon, N. (2010). FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 143, 813-825.
12. El-Haddad, H., Champion, H. C., Danner, T. A., Rao, S. S., Mulhearn, T. J., Haile, A., Gebska, M., Hemnes, A., Hager, M., Breton, M. et al. (2011). Exercise training improves cardiac function and restores nuclear localization of pAKT in aged mice. Circulation 124, A8264.
13. Fitts, R. H. and Widrick, J. J. (1996). Muscle mechanics: adaptations with exercisetraining. Exerc. Sport Sci. Rev. 24, 427-473.
14. Freyssenet, D., Berthon, P. and Denis, C. (1996). Mitochondrial biogenesis in skeletal muscle in response to endurance exercises. Arch. Physiol. Biochem. 104, 129-141.
15. Gargano, J. W., Martin, I., Bhandari, P. and Grotewiel, M. S. (2005). Rapid iterative negative geotaxis (RING): a new method for assessing age-related locomotor decline in Drosophila. Exp. Gerontol. 40, 386-395.
16. Graham, T. E. and Adamo, K. B. (1999). Dietary carbohydrate and its effects on metabolism and substrate stores in sedentary and active individuals. Can. J. Appl. Physiol. 24, 393-415.
17. Grandison, R. C., Wong, R., Bass, T. M., Partridge, L. and Piper, M. D. W. (2009). Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster. PLoS ONE 4, e4067.
18. Hall, K. D., Heymsfield, S. B., Kemnitz, J. W., Klein, S., Schoeller, D. A. and Speakman, J. R. (2012). Energy balance and its components: implications for body weight regulation. Am. J. Clin. Nutr. 95, 989-994.
19. Hayashi, T., Wojtaszewski, J. F. P. and Goodyear, L. J. (1997). Exercise regulation of glucose transport in skeletal muscle. Am. J. Physiol. 273, E1039-E1051.
20. He, C. C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y. J., Zou, Z. J., An, Z., Loh, J., Fisher, J., Sun, Q. et al. (2012). Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481, 511-515.
21. Henriksson, J. (1995). Influence of exercise on insulin sensitivity. J. Cardiovasc. Risk 2, 303-309.
22. Hopps, E. and Caimi, G. (2011). Exercise in obesity management. J. Sports Med. Phys. Fitness 51, 275-282.
23. Irrcher, I., Adhihetty, P. J., Joseph, A. M., Ljubicic, V. and Hood, D. A. (2003). Regulation of mitochondrial biogenesis in muscle by endurance exercise. Sports Med. 33, 783-793.
24. Jones, M. A. and Grotewiel, M. (2011). Drosophila as a model for age-related impairment in locomotor and other behaviors. Exp. Gerontol. 46, 320-325.
25. Kemi, O. J. and Wisloff, U. (2010). High-intensity aerobic exercise training improves the heart in health and disease. J. Cardiopulm. Rehabil. Prev. 30, 2-11.
26. Lee, K. P., Simpson, S. J., Clissold, F. J., Brooks, R., Ballard, J. W. O., Taylor, P. W., Soran, N. and Raubenheimer, D. (2008). Lifespan and reproduction in Drosophila: new insights from nutritional geometry. Proc. Natl. Acad. Sci. USA 105, 2498-2503.
27. Lim, H. Y., Wang, W. D., Wessells, R. J., Ocorr, K. and Bodmer, R. (2011). Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes Dev. 25, 189-200.
28. Linford, N. J., Chan, T. P. and Pletcher, S. D. (2012). Re-patterning sleep architecture in Drosophila through gustatory perception and nutritional quality. PLoS Genet. 8, e1002668.
29. Luong, N., Davies, C. R., Wessells, R. J., Graham, S. M., King, M. T., Veech, R., Bodmer, R. and Oldham, S. M. (2006). Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity. Cell Metab. 4, 133-142.
30. Lushchak, O. V., Gospodaryov, D. V., Rovenko, B. M., Glovyak, A. D., Yurkevych, I. S., Klyuba, V. P., Shcherbij, M. V. and Lushchak, V. I. (2012). Balance between macronutrients affects life span and functional senescence in fruit fly Drosophila melanogaster. J. Gerontol. A Biol. Sci. Med. Sci. 67A, 118-125.
31. Mair, W., Piper, M. D. and Partridge, L. (2005). Calories do not explain extension of life span by dietary restriction in Drosophila. PLoS Biol. 3, e223.
32. Martin, W. H. 3rd and Klein, S. (1998). Use of endogenous carbohydrate and fat as fuels during exercise. Proc. Nutr. Soc. 57, 49-54.
33. Matoba, H. and Gollnick, P. D. (1984). Response of skeletal muscle to training. Sports Med. 1, 240-251.
34. Mercken, E. M., Carboneau, B. A., Krzysik-Walker, S. M. and de Cabo, R. (2012). Of mice and men: the benefits of caloric restriction, exercise, and mimetics. Ageing Res. Rev. 11, 390-398.
35. Miller, R. A., Buehner, G., Chang, Y., Harper, J. M., Sigler, R. and Smith-Wheelock, M. (2005). Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 4, 119-125.
36. Parashar, V. and Rogina, B. (2009). dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction. Aging (Albany NY) 1, 529-541.
37. Partridge, L., Piper, M. D. W. and Mair, W. (2005). Dietary restriction in Drosophila. Mech. Ageing Dev. 126, 938-950.
38. Partridge, L., Alic, N., Bjedov, I. and Piper, M. D. W. (2011). Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Exp. Gerontol. 46, 376-381.
39. Piazza, N., Gosangi, B., Devilla, S., Arking, R. and Wessells, R. (2009). Exercisetraining in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performance. PLoS ONE 4, e5886.
40. Piper, M. D. W., Mair, W. and Partridge, L. (2005). Counting the calories: the role of specific nutrients in extension of life span by food restriction. J. Gerontol. A Biol. Sci. Med. Sci. 60A, 549-555.
41. Russo, S. B., Baicu, C. F., Van Laer, A., Geng, T., Kasiganesan, H., Zile, M. R. and Cowart, L. A. (2012). Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J. Clin. Invest. 122, 3919-3930.
42. Simpson, S. J. and Raubenheimer, D. (2009). Macronutrient balance and lifespan. Aging (Albany NY) 1, 875-880.
43. Skorupa, D. A., Dervisefendic, A., Zwiener, J. and Pletcher, S. D. (2008). Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster. Aging Cell 7, 478-490.
44. Sujkowski, A., Saunders, S., Tinkerhess, M., Piazza, N., Jennens, J., Healy, L., Zheng, L. and Wessells, R. (2012). dFatp regulates nutrient distribution and longterm physiology in Drosophila. Aging Cell 11, 921-932.
45. Sun, L., Sadighi Akha, A. A., Miller, R. A. and Harper, J. M. (2009). Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age. J. Gerontol. A Biol. Sci. Med. Sci. 64A, 711-722.
46. Tinkerhess, M. J., Ginzberg, S., Piazza, N. and Wessells, R. J. (2012a). Endurance training protocol and longitudinal performance assays for Drosophila melanogaster. J. Vis. Exp. 61, e3786.
47. Tinkerhess, M. J., Healy, L., Morgan, M., Sujkowski, A., Matthys, E., Zheng, L. and Wessells, R. J. (2012b). The Drosophila PGC-1α homolog spargel modulates the physiological effects of endurance exercise. PLoS ONE 7, e31633.
48. Vijendravarma, R. K., Narasimha, S. and Kawecki, T. J. (2012). Adaptation to abundant low quality food improves the ability to compete for limited rich food in Drosophila melanogaster. PLoS ONE 7, e30650.
49. Wessells, R. J., Fitzgerald, E., Cypser, J. R., Tatar, M. and Bodmer, R. (2004). Insulin regulation of heart function in aging fruit flies. Nat. Genet. 36, 1275-1281.
50. Wessells, R., Fitzgerald, E., Piazza, N., Ocorr, K., Morley, S., Davies, C., Lim, H. Y., Elmén, L., Hayes, M., Oldham, S. et al. (2009). d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging Cell 8, 542-552.
51. Wong, R., Piper, M. D. W., Wertheim, B. and Partridge, L. (2009). Quantification of food intake in Drosophila. PLoS ONE 4, e6063.