Probing alanine transaminase catalysis with hyperpolarized 13CD3-pyruvate

Journal of Magnetic Resonance

Volumn 228, Issue , 2013, Pages 59-65

  Barb, A W ^a   Hekmatyar, S K ^a   Glushka, J N ^a   Prestegard, J H ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Dissolution dynamic nuclear polarization; Magnetic resonance imaging; Metabolic biomarkers; Nuclear magnetic resonance spectroscopy

Indexed keywords

DISSOLUTION DYNAMICS; ENAMINE INTERMEDIATES; EXPERIMENTAL APPROACHES; H-D EXCHANGE; HYPERPOLARIZATION; HYPERPOLARIZED; IMAGING APPLICATIONS; INDIRECT DETECTION; LIVER DISEASE; LIVING TISSUES; MECHANISTIC STUDIES; METABOLIC BIOMARKERS; METABOLITE CONCENTRATIONS; METHYL GROUP; MOLECULAR SIGNATURES; NITROGEN DONORS; PYRUVATES; PYRUVIC ACID; TIME-SCALES; WELL-ESTABLISHED BIOMARKERS;

BIOMARKERS; CATALYSIS; DISSOLUTION; FUNCTIONAL GROUPS; MAGNETIC RESONANCE IMAGING; MECHANICS; METABOLITES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTONS; SPIN POLARIZATION; TISSUE;

AMINO ACIDS;

ALANINE AMINOTRANSFERASE; CARBON; DEUTERIUM; PROTON; PYRUVIC ACID;

ARTICLE; CATALYSIS; CHEMISTRY; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; SENSITIVITY AND SPECIFICITY; SIGNAL PROCESSING;

ALANINE TRANSAMINASE; CARBON ISOTOPES; CATALYSIS; DEUTERIUM; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTONS; PYRUVIC ACID; SENSITIVITY AND SPECIFICITY; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 84874155105     PISSN: 10907807     EISSN: 10960856     Source Type: Journal    
DOI: 10.1016/j.jmr.2012.12.013     Document Type: Article

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