The late and persistent pathogenic effects of cadmium at very low levels on the kidney of rats

Dose-Response

Volumn 11, Issue 1, 2013, Pages 60-81

  Wang, Bo ^a,b,c   Luo, Qi ^d   Shao, Chen ^a   Li, Xin ^a   Li, Feng ^a   Liu, Yanan ^a   Sun, Liankun ^a   Li, Yang ^a   Cai, Lu ^e  

^a Basic Medical College   (China)

^b Inner Mongolia Forestry General Hospital   (China)

^c University of Louisville School of Medicine   (United States)

^d THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^e UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Cadmium; Methylation; Persistent effect; Renal dysfunction; Renal toxicity

Indexed keywords

3 NITROTYROSINE; CADMIUM; GLUTATHIONE; METALLOTHIONEIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CADMIUM POISONING; CELL PROLIFERATION; CELL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; GLOMERULUS; HISTOPATHOLOGY; HYPERPLASIA; IMMUNOREACTIVITY; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY TUBULE DISORDER; MALE; MORPHOLOGY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

EID: 84874101353     PISSN: None     EISSN: 15593258     Source Type: Journal    
DOI: 10.2203/dose-response.11-046.Wang     Document Type: Article

References (52)

1. Amara S, Abdelmelek H, Garrel C, Guiraud P, Douki T, Ravanat JL, Favier A, Sakly M and Ben Rhouma K. 2006. Influence of static magnetic field on cadmium toxicity: study of oxidative stress and DNA damage in rat tissues. J Trace Elem Med Biol 20: 263-269.
2. Asagba SO and Obi FO. 2005. A comparative evaluation of the biological effects of environmental cadmium-contaminated control diet and laboratory-cadmium supplemented test diet. Biometals 18: 155-161.
3. ATSDR (Agency for Toxic Subtances and Disease Registry). 2004. Resources for information on asbestos and asbestos-related disease. Available at http://www.atsdr.cdc.gov/interactionprofiles/ipga.html
4. 111Cd-superoxide dismutase derivative. Biochem Biophys Res Commun 94: 1296-1302.
5. Bernard A, Roels H, Buchet JP, Cardenas A and Lauwerys R. 1992. Cadmium and health: the Belgian experience. IARC Sci Publ (118): 15-33.
6. Bernard A. 2004. Renal dysfunction induced by cadmium: biomarkers of critical effects. Biometals 17: 519-523.
7. Bernard AM, Roels H, Cardenas A and Lauwerys R. 1990. Assessment of urinary protein 1 and transferrin as early markers of cadmium nephrotoxicity. Br J Ind Med 47: 559-565.
8. Cai L, Satoh M, Tohyama C and Cherian MG. 1999. Metallothionein in radiation exposure: its induction and protective role. Toxicology 132: 85-98.
9. Cai L, Klein JB and Kang YJ. 2000. Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage. J Biol Chem 275: 38957-38960.
10. Callegaro MG, Milbradt BG, Diettrich T, Alves E, Duarte FA, Flores EM, Dressler VL, Silva LP and Emanuelli T. 2010. Influence of cereal bran supplement on cadmium effects in growing rats. Hum Exp Toxicol 29: 467-476.
11. Casalino E, Calzaretti G, Sblano C and Landriscina C. 2000. Cadmium-dependent enzyme activity alteration is not imputable to lipid peroxidation. Arch Biochem Biophys 383: 288-295.
12. Cherian MG, Jayasurya A and Bay BH. 2003. Metallothioneins in human tumors and potential roles in carcinogenesis. Mutation research 533: 201-209.
13. Conner EA and Fowler BA. 1993. Toxicology of the kidney. Raven Press Ltd.: 437-457.
14. Cooper RG. 2006. Effect of tobacco smoking on renal function. Indian J Med Res 124: 261-268.
15. El-Maraghy SA, Gad MZ, Fahim AT and Hamdy MA. 2001. Effect of cadmium and aluminum intake on the antioxidant status and lipid peroxidation in rat tissues. J Biochem Mol Toxicol 15: 207-214.
16. Groten JP, Sinkeldam EJ, Luten JB, van Bladeren PJ. (1991). Cadmium accumulation and metallothionein concentrations after 4-week dietary exposure to cadmium chloride or cadmium-metallothionein in rats. Toxicol Appl Pharmacol. 111:504-513.
17. Haouem S, Hmad N, Najjar MF, El Hani A and Sakly R. 2007. Accumulation of cadmium and its effects on liver and kidney functions in rats given diet containing cadmium-polluted radish bulb. Exp Toxicol Pathol 59: 77-80.
18. Hradilova J, Rehulka P, Rehulkova H, Vrbova M, Griga M and Brzobohaty B. 2010. Comparative analysis of proteomic changes in contrasting flax cultivars upon cadmium exposure. Electrophoresis 31: 421-431.
19. Jarup L and Alfven T. 2004. Low level cadmium exposure, renal and bone effects-the OSCAR study. Biometals 17: 505-509.
20. Jarup L, Hellstrom L, Alfven T, Carlsson MD, Grubb A, Persson B, Pettersson C, Spang G, Schutz A and Elinder CG. 2000. Low level exposure to cadmium and early kidney damage: the OSCAR study. Occup Environ Med 57: 668-672.
21. Jarup L. 2002. Cadmium overload and toxicity. Nephrol Dial Transplant 17 Suppl 2: 35-39.
22. Jiang G, Xu L, Song S, Zhu C, Wu Q, Zhang L and Wu L. 2008. Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells. Toxicology 244: 49-55.
23. Klein G. 2005. Epigenetics: surveillance team against cancer. Nature 434: 150.
24. Koizumi N, Murata K, Hayashi C, Nishio H and Goji J. 2008. High cadmium accumulation among humans and primates: comparison across various mammalian species-a study from Japan. Biol Trace Elem Res 121: 205-214.
25. LaSarge C and Nicolle M. 2009. Comparison of Different Cognitive Rat Models of Human Aging Animal Models of Human Cognitive Aging 30.
26. Liu J, Liu Y, Habeebu SS and Klaassen CD. 1998. Susceptibility of MT-null mice to chronic CdCl2- induced nephrotoxicity indicates that renal injury is not mediated by the CdMT complex. Toxicol Sci 46: 197-203.
27. Liu J, Liu Y, Goyer RA, Achanzar W and Waalkes MP. 2000. Metallothionein-I/II null mice are more sensitive than wild-type mice to the hepatotoxic and nephrotoxic effects of chronic oral or injected inorganic arsenicals. Toxicol Sci 55: 460-467.
28. McCarty KS, Jr., Miller LS, Cox EB, Konrath J and McCarty KS, Sr. 1985. Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. Arch Pathol Lab Med 109: 716-721.
29. Mead MN. 2010. Cadmium confusion: do consumers need protection? Environ Health Perspect 118: a528-534.
30. Moulis JM and Thevenod F. 2010. New perspectives in cadmium toxicity: an introduction. Biometals 23: 763-768.
31. Nakagawa H and Nishijo M. 1996. Environmental cadmium exposure, hypertension and cardiovascular risk. J Cardiovasc Risk 3: 11-17.
32. Quig, D. 1998. Cyteine metabolism and metal toxicity. Alter. Med. Rev. 3: 262-270
33. Renugadevi J and Prabu SM. 2010. Quercetin protects against oxidative stress-related renal dysfunction by cadmium in rats. Exp Toxicol Pathol 62: 471-481.
34. Satarug S and Moore MR. 2004. Adverse health effects of chronic exposure to low-level cadmium in foodstuffs and cigarette smoke. Environ Health Perspect 112: 1099-1103.
35. Sato M and Kondoh M. 2002. Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals. Tohoku J Exp Med 196: 9-22.
36. Sato M and Bremner I. 1993. Oxygen free radicals and metallothionein. Free Radic Biol Med 14: 325-337.
37. Schwerdtle T, Ebert F, Thuy C, Richter C, Mullenders LH and Hartwig A. 2010. Genotoxicity of soluble and particulate cadmium compounds: impact on oxidative DNA damage and nucleotide excision repair. Chem Res Toxicol 23: 432-442.
38. Shibasaki T, Xu QY, Ohno I, Ishimoto F and Sakai O. 1996. The influence of aging on renal response to cadmium in Syrian hamsters. Biol Trace Elem Res 54: 87-95.
39. Singh KP, Kumari R, Pevey C, Jackson D and DuMond JW. 2009. Long duration exposure to cadmium leads to increased cell survival, decreased DNA repair capacity, and genomic instability in mouse testicular Leydig cells. Cancer Lett 279: 84-92.
40. Song Y, Li C and Cai L. 2004. Fluvastatin prevents nephropathy likely through suppression of connective tissue growth factor-mediated extracellular matrix accumulation. Exp Mol Pathol 76: 66-75.
41. Stohs SJ, Bagchi D, Hassoun E and Bagchi M. 2001. Oxidative mechanisms in the toxicity of chromium and cadmium ions. J Environ Pathol Toxicol Oncol 20: 77-88.
42. Takahashi Y, Ishii Y, Nagata T, Ikarashi M, Ishikawa K and Asai S. 2003. Clinical application of oligonucleotide probe array for full-length gene sequencing of TP53 in colon cancer. Oncology 64: 54-60.
43. Takaki A, Jimi S, Segawa M and Iwasaki H. 2004. Cadmium-induced nephropathy in rats is mediated by expression of senescence-associated beta-galactosidase and accumulation of mitochondrial DNA deletion. Ann N Y Acad Sci 1011: 332-338.
44. Uchida M, Teranishi H, Aoshima K, Katoh T, Kasuya M and Inadera H. 2004. Reduction of erythrocyte catalase and superoxide dismutase activities in male inhabitants of a cadmium-polluted area in Jinzu river basin, Japan. Toxicol Lett 151: 451-457.
45. Uriu K, Kaizu K, Qie YL, Ito A, Takagi I, Suzuka K, Inada Y, Hashimoto O and Eto S. 2000. Long-term oral intake of low-dose cadmium exacerbates age-related impairment of renal functional reserve in rats. Toxicol Appl Pharmacol 169: 151-158.
46. Waalkes MP. 2000. Cadmium carcinogenesis in review. J Inorg Biochem 79: 241-244.
47. Waalkes MP. 2003. Cadmium carcinogenesis. Mutat Res 533: 107-120.
48. Waisberg M, Joseph P, Hale B and Beyersmann D. 2003. Molecular and cellular mechanisms of cadmium carcinogenesis. Toxicology 192: 95-117.
49. Wang B, Wang S, Shao C, Wang G, Li Y and Cai L. 2011. Proteomic characterization of the late and persistent effects of cadmium at low doses on the rat liver. Journal of Applied Toxicology Inpress.
50. Xu B, Xu ZF, Deng Y and Yang JH. 2010. Protective effects of Chlorpromazine and Verapamil against cadmium-induced kidney damage in vivo. Exp Toxicol Pathol 62: 27-34.
51. Zager RA. 2005. Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy. Kidney Int 68: 1533-1542.
52. Zalups RK and Ahmad S. 2003. Molecular handling of cadmium in transporting epithelia. Toxicology and applied pharmacology 186: 163-188.