Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 50, 2006, Pages 19194-19199

  Laxman, Sunil ^a   Riechers, Aaron ^b   Sadilek, Martin ^b   Schwede, Frank ^c   Beavo, Joseph A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c BIOLOG Life Science Institute   (Germany)

Author keywords

Adenosine; EPACs; Phosphodiesterases; Trypanosomes

Indexed keywords

ADENOSINE DERIVATIVE; CYCLIC AMP; NUCLEOTIDE; PHOSPHODIESTERASE; DRUG DERIVATIVE; ETAZOLATE; PHOSPHODIESTERASE INHIBITOR;

AFRICAN TRYPANOSOMIASIS; ARTICLE; BLOOD FLOW; CELL PROLIFERATION; HOST PARASITE INTERACTION; HYDROLYSIS; LIFE CYCLE; MEMBRANE PERMEABILITY; METABOLISM; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI; ANIMAL; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING;

HEXAPODA; MAMMALIA; TRYPANOSOMA BRUCEI;

ANIMALS; CELL MEMBRANE PERMEABILITY; CYCLIC AMP; ETAZOLATE; HYDROLYSIS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; TRYPANOSOMA BRUCEI BRUCEI;

EID: 35548951903     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0608971103     Document Type: Article

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