Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 4, 2013, Pages

  Gadhia, Monika M ^a   Maliszewski, Anne M ^a   O'Meara, Meghan C ^a   Thorn, Stephanie R ^a   Lavezzi, Jinny R ^a   Limesand, Sean W ^b   Hay, William W ^a   Brown, Laura D ^a,c   Rozance, Paul J ^a,c  

^a Perinatal Research Center   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Glucagon; Metabolism; Pancreas; Pregnancy; cell

Indexed keywords

6 PHOSPHOFRUCTOKINASE; AMINO ACID MIXTURE; ARGININE; BRANCHED CHAIN AMINO ACID; CARBON DIOXIDE; CYTOCHROME C; ESTROGEN RELATED RECEPTOR ALPHA; GLUCAGON; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER 2; HYDROCORTISONE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR B; MESSENGER RNA; NORADRENALIN; OXYGEN; SODIUM CHLORIDE; SOMATOMEDIN C; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD PH; CELL STIMULATION; CONTROLLED STUDY; FETUS; GESTATIONAL AGE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HEMATOCRIT; HYDROCORTISONE BLOOD LEVEL; IN VIVO STUDY; INSULIN RELEASE; INSULIN SENSITIVITY; NONHUMAN; NORADRENALIN BLOOD LEVEL; ORGAN WEIGHT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SHEEP;

EID: 84874024623     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00377.2012     Document Type: Article

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