Salinomycin induces apoptosis and senescence in breast cancer: Upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 4, 2013, Pages 3121-3135

  Al Dhaheri, Yusra ^a   Attoub, Samir ^b   Arafat, Kholoud ^b   Abuqamar, Synan ^a   Eid, Ali ^a,c   Al Faresi, Nesreen ^a   Iratni, Rabah ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^c Qatar University ^*  (Qatar)

Author keywords

Apoptosis; DNA damage; Histone hyperacetylation; p21; Salinomycin; Senescence associated beta galactosidase (SA Gal)

Indexed keywords

AFIMOXIFENE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; FRONDOSIDE A; HISTONE H3; HISTONE H4; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P21; SALINOMYCIN; SURVIVIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ACETYLATION; ANTI-BACTERIAL AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL AGING; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOSKELETAL PROTEINS; FEMALE; G2 PHASE; GLYCOSIDES; HISTONES; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; PYRANS; TRITERPENES;

EID: 84874007556     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.01.010     Document Type: Article

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