메뉴 건너뛰기




Volumn 15, Issue 1, 2013, Pages

IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; LIPOCORTIN 5; NITROPRUSSIDE SODIUM; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; STAT3 PROTEIN; IL17A PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN;

EID: 84873963986     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4179     Document Type: Article
Times cited : (96)

References (42)
  • 1
    • 0030003058 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • 10.1016/S0092-8674(00)81109-5, 8616886
    • Feldmann M, Brennan FM, Maini RN. Rheumatoid arthritis. Cell 1996, 85:307-310. 10.1016/S0092-8674(00)81109-5, 8616886.
    • (1996) Cell , vol.85 , pp. 307-310
    • Feldmann, M.1    Brennan, F.M.2    Maini, R.N.3
  • 2
    • 0029914194 scopus 로고    scopus 로고
    • Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?
    • 10.1002/art.1780391103, 8912499
    • Firestein GS. Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?. Arthritis Rheum 1996, 39:1781-1790. 10.1002/art.1780391103, 8912499.
    • (1996) Arthritis Rheum , vol.39 , pp. 1781-1790
    • Firestein, G.S.1
  • 3
    • 0026033431 scopus 로고
    • Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts
    • 10.1084/jem.173.3.569, 2118837, 1997647
    • Bucala R, Ritchlin C, Winchester R, Cerami A. Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts. J Exp Med 1991, 173:569-574. 10.1084/jem.173.3.569, 2118837, 1997647.
    • (1991) J Exp Med , vol.173 , pp. 569-574
    • Bucala, R.1    Ritchlin, C.2    Winchester, R.3    Cerami, A.4
  • 4
    • 0028216495 scopus 로고
    • Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue
    • 10.1084/jem.180.1.341, 2191547, 8006592
    • Fava RA, Olsen NJ, Spencer-Green G, Yeo KT, Yeo TK, Berse B, Jackman RW, Senger DR, Dvorak HF, Brown LF. Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J Exp Med 1994, 180:341-346. 10.1084/jem.180.1.341, 2191547, 8006592.
    • (1994) J Exp Med , vol.180 , pp. 341-346
    • Fava, R.A.1    Olsen, N.J.2    Spencer-Green, G.3    Yeo, K.T.4    Yeo, T.K.5    Berse, B.6    Jackman, R.W.7    Senger, D.R.8    Dvorak, H.F.9    Brown, L.F.10
  • 5
    • 0034657793 scopus 로고    scopus 로고
    • CD40 engagement on synovial fibroblast up-regulates production of vascular endothelial growth factor
    • Cho CS, Cho ML, Min SY, Kim WU, Min DJ, Lee SS, Park SH, Choe J, Kim HY. CD40 engagement on synovial fibroblast up-regulates production of vascular endothelial growth factor. J Immunol 2000, 164:5055-5061.
    • (2000) J Immunol , vol.164 , pp. 5055-5061
    • Cho, C.S.1    Cho, M.L.2    Min, S.Y.3    Kim, W.U.4    Min, D.J.5    Lee, S.S.6    Park, S.H.7    Choe, J.8    Kim, H.Y.9
  • 6
    • 70449651889 scopus 로고    scopus 로고
    • The role of interleukin-17 in the pathogenesis of rheumatoid arthritis
    • 10.1007/s11926-009-0052-y, 2811488, 19772832
    • Gaffen SL. The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Curr Rheumatol Rep 2009, 11:365-370. 10.1007/s11926-009-0052-y, 2811488, 19772832.
    • (2009) Curr Rheumatol Rep , vol.11 , pp. 365-370
    • Gaffen, S.L.1
  • 7
    • 67651175878 scopus 로고    scopus 로고
    • Breaking old paradigms: Th17 cells in autoimmune arthritis
    • 10.1016/j.clim.2009.03.522, 2720426, 19403336
    • Peck A, Mellins ED. Breaking old paradigms: Th17 cells in autoimmune arthritis. Clin Immunol 2009, 132:295-304. 10.1016/j.clim.2009.03.522, 2720426, 19403336.
    • (2009) Clin Immunol , vol.132 , pp. 295-304
    • Peck, A.1    Mellins, E.D.2
  • 9
    • 0030886724 scopus 로고    scopus 로고
    • Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium
    • 10.1073/pnas.94.20.10895, 23522, 9380731
    • Firestein GS, Echeverri F, Yeo M, Zvaifler NJ, Green DR. Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. Proc Natl Acad Sci USA 1997, 94:10895-10900. 10.1073/pnas.94.20.10895, 23522, 9380731.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10895-10900
    • Firestein, G.S.1    Echeverri, F.2    Yeo, M.3    Zvaifler, N.J.4    Green, D.R.5
  • 10
    • 29844438612 scopus 로고    scopus 로고
    • Fas (CD95)-related apoptosis and rheumatoid arthritis
    • Peng SL. Fas (CD95)-related apoptosis and rheumatoid arthritis. Rheumatology (Oxford) 2006, 45:26-30.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 26-30
    • Peng, S.L.1
  • 11
    • 55149113836 scopus 로고    scopus 로고
    • The roles of IL-17A in inflammatory immune responses and host defense against pathogens
    • 10.1111/j.1600-065X.2008.00699.x, 19161416
    • Iwakura Y, Nakae S, Saijo S, Ishigame H. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol Rev 2008, 226:57-79. 10.1111/j.1600-065X.2008.00699.x, 19161416.
    • (2008) Immunol Rev , vol.226 , pp. 57-79
    • Iwakura, Y.1    Nakae, S.2    Saijo, S.3    Ishigame, H.4
  • 12
    • 79953310900 scopus 로고    scopus 로고
    • Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes
    • 10.1136/ard.2010.143768, 21345813
    • Hot A, Miossec P. Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes. Ann Rheum Dis 2011, 70:727-732. 10.1136/ard.2010.143768, 21345813.
    • (2011) Ann Rheum Dis , vol.70 , pp. 727-732
    • Hot, A.1    Miossec, P.2
  • 13
    • 0028303977 scopus 로고
    • Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
    • 10.1016/0092-8674(94)90235-6, 7512451
    • Akira S, Nishio Y, Inoue M, Wang XJ, Wei S, Matsusaka T, Yoshida K, Sudo T, Naruto M, Kishimoto T. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 1994, 77:63-71. 10.1016/0092-8674(94)90235-6, 7512451.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1    Nishio, Y.2    Inoue, M.3    Wang, X.J.4    Wei, S.5    Matsusaka, T.6    Yoshida, K.7    Sudo, T.8    Naruto, M.9    Kishimoto, T.10
  • 14
    • 34247593586 scopus 로고    scopus 로고
    • STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
    • 10.1074/jbc.C600321200, 17277312
    • Yang XO, Panopoulos AD, Nurieva R, Chang SH, Wang D, Watowich SS, Dong C. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem 2007, 282:9358-9363. 10.1074/jbc.C600321200, 17277312.
    • (2007) J Biol Chem , vol.282 , pp. 9358-9363
    • Yang, X.O.1    Panopoulos, A.D.2    Nurieva, R.3    Chang, S.H.4    Wang, D.5    Watowich, S.S.6    Dong, C.7
  • 15
    • 33745894354 scopus 로고    scopus 로고
    • Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis
    • 10.1002/art.21942, 16802343
    • Nowell MA, Richards PJ, Fielding CA, Ognjanovic S, Topley N, Williams AS, Bryant-Greenwood G, Jones SA. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis Rheum 2006, 54:2084-2095. 10.1002/art.21942, 16802343.
    • (2006) Arthritis Rheum , vol.54 , pp. 2084-2095
    • Nowell, M.A.1    Richards, P.J.2    Fielding, C.A.3    Ognjanovic, S.4    Topley, N.5    Williams, A.S.6    Bryant-Greenwood, G.7    Jones, S.A.8
  • 16
    • 2642588293 scopus 로고    scopus 로고
    • Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice
    • 10.1002/art.20302, 15188379
    • de Hooge AS, van de Loo FA, Koenders MI, Bennink MB, Arntz OJ, Kolbe T, van den Berg WB. Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. Arthritis Rheum 2004, 50:2014-2023. 10.1002/art.20302, 15188379.
    • (2004) Arthritis Rheum , vol.50 , pp. 2014-2023
    • de Hooge, A.S.1    van de Loo, F.A.2    Koenders, M.I.3    Bennink, M.B.4    Arntz, O.J.5    Kolbe, T.6    van den Berg, W.B.7
  • 17
    • 0025176086 scopus 로고
    • Separation of events mediating B cell proliferation and Ig production by using T cell membranes and lymphokines
    • Hodgkin PD, Yamashita LC, Coffman RL, Kehry MR. Separation of events mediating B cell proliferation and Ig production by using T cell membranes and lymphokines. J Immunol 1990, 145:2025-2034.
    • (1990) J Immunol , vol.145 , pp. 2025-2034
    • Hodgkin, P.D.1    Yamashita, L.C.2    Coffman, R.L.3    Kehry, M.R.4
  • 18
    • 78149438748 scopus 로고    scopus 로고
    • Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression
    • 10.1371/journal.pone.0013416, 2955522, 20976214
    • Toh ML, Gonzales G, Koenders MI, Tournadre A, Boyle D, Lubberts E, Zhou Y, Firestein GS, van den Berg WB, Miossec P. Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression. PLoS One 2010, 5:e13416. 10.1371/journal.pone.0013416, 2955522, 20976214.
    • (2010) PLoS One , vol.5
    • Toh, M.L.1    Gonzales, G.2    Koenders, M.I.3    Tournadre, A.4    Boyle, D.5    Lubberts, E.6    Zhou, Y.7    Firestein, G.S.8    van den Berg, W.B.9    Miossec, P.10
  • 20
    • 39649113592 scopus 로고    scopus 로고
    • Immunopathogenesis of psoriasis
    • 10.1007/s12016-007-0039-2, 18094946
    • Nickoloff BJ, Qin JZ, Nestle FO. Immunopathogenesis of psoriasis. Clin Rev Allergy Immunol 2007, 33:45-56. 10.1007/s12016-007-0039-2, 18094946.
    • (2007) Clin Rev Allergy Immunol , vol.33 , pp. 45-56
    • Nickoloff, B.J.1    Qin, J.Z.2    Nestle, F.O.3
  • 21
    • 67349230808 scopus 로고    scopus 로고
    • The IL-23/Th17 axis in the immunopathogenesis of psoriasis
    • 10.1038/jid.2009.59, 19322214
    • Di Cesare A, Di Meglio P, Nestle FO. The IL-23/Th17 axis in the immunopathogenesis of psoriasis. J Invest Dermatol 2009, 129:1339-1350. 10.1038/jid.2009.59, 19322214.
    • (2009) J Invest Dermatol , vol.129 , pp. 1339-1350
    • Di Cesare, A.1    Di Meglio, P.2    Nestle, F.O.3
  • 22
    • 34548133584 scopus 로고    scopus 로고
    • Multiple sclerosis: a complicated picture of autoimmunity
    • 10.1038/ni1507, 17712344
    • McFarland HF, Martin R. Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol 2007, 8:913-919. 10.1038/ni1507, 17712344.
    • (2007) Nat Immunol , vol.8 , pp. 913-919
    • McFarland, H.F.1    Martin, R.2
  • 23
    • 74049161287 scopus 로고    scopus 로고
    • Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease
    • 10.3748/wjg.15.5784, 2791270, 19998498
    • Liu ZJ, Yadav PK, Su JL, Wang JS, Fei K. Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease. World J Gastroenterol 2009, 15:5784-5788. 10.3748/wjg.15.5784, 2791270, 19998498.
    • (2009) World J Gastroenterol , vol.15 , pp. 5784-5788
    • Liu, Z.J.1    Yadav, P.K.2    Su, J.L.3    Wang, J.S.4    Fei, K.5
  • 24
    • 56349118794 scopus 로고    scopus 로고
    • The IL-17 cytokine family and their role in allergic inflammation
    • 10.1016/j.coi.2008.09.004, 18832032
    • Wang YH, Liu YJ. The IL-17 cytokine family and their role in allergic inflammation. Curr Opin Immunol 2008, 20:697-702. 10.1016/j.coi.2008.09.004, 18832032.
    • (2008) Curr Opin Immunol , vol.20 , pp. 697-702
    • Wang, Y.H.1    Liu, Y.J.2
  • 25
    • 13444256307 scopus 로고    scopus 로고
    • The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models
    • 10.1186/ar1478, 1064899, 15642151
    • Lubberts E, Koenders MI, van den Berg WB. The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther 2005, 7:29-37. 10.1186/ar1478, 1064899, 15642151.
    • (2005) Arthritis Res Ther , vol.7 , pp. 29-37
    • Lubberts, E.1    Koenders, M.I.2    van den Berg, W.B.3
  • 26
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003, 171:6173-6177.
    • (2003) J Immunol , vol.171 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 27
    • 1042267236 scopus 로고    scopus 로고
    • Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion
    • 10.1002/art.20001, 14872510
    • Lubberts E, Koenders MI, Oppers-Walgreen B, van den Bersselaar L, Coenen-de Roo CJ, Joosten LA, van den Berg WB. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum 2004, 50:650-659. 10.1002/art.20001, 14872510.
    • (2004) Arthritis Rheum , vol.50 , pp. 650-659
    • Lubberts, E.1    Koenders, M.I.2    Oppers-Walgreen, B.3    van den Bersselaar, L.4    Coenen-de Roo, C.J.5    Joosten, L.A.6    van den Berg, W.B.7
  • 28
    • 26844554064 scopus 로고    scopus 로고
    • Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis
    • 10.1002/art.21342, 16200598
    • Koenders MI, Kolls JK, Oppers-Walgreen B, van den Bersselaar L, Joosten LA, Schurr JR, Schwarzenberger P, van den Berg WB, Lubberts E. Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum 2005, 52:3239-3247. 10.1002/art.21342, 16200598.
    • (2005) Arthritis Rheum , vol.52 , pp. 3239-3247
    • Koenders, M.I.1    Kolls, J.K.2    Oppers-Walgreen, B.3    van den Bersselaar, L.4    Joosten, L.A.5    Schurr, J.R.6    Schwarzenberger, P.7    van den Berg, W.B.8    Lubberts, E.9
  • 29
    • 0032939156 scopus 로고    scopus 로고
    • Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
    • 10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E, 10323452
    • Chabaud M, Durand JM, Buchs N, Fossiez F, Page G, Frappart L, Miossec P. Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 1999, 42:963-970. 10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E, 10323452.
    • (1999) Arthritis Rheum , vol.42 , pp. 963-970
    • Chabaud, M.1    Durand, J.M.2    Buchs, N.3    Fossiez, F.4    Page, G.5    Frappart, L.6    Miossec, P.7
  • 31
    • 5644289875 scopus 로고    scopus 로고
    • IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways
    • 10.1186/ar1038, 400429, 15059275
    • Hwang SY, Kim JY, Kim KW, Park MK, Moon Y, Kim WU, Kim HY. IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways. Arthritis Res Ther 2004, 6:R120-128. 10.1186/ar1038, 400429, 15059275.
    • (2004) Arthritis Res Ther , vol.6
    • Hwang, S.Y.1    Kim, J.Y.2    Kim, K.W.3    Park, M.K.4    Moon, Y.5    Kim, W.U.6    Kim, H.Y.7
  • 32
    • 0035465260 scopus 로고    scopus 로고
    • Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes
    • 10.1002/1529-0131(200109)44:9<2176::AID-ART371>3.0.CO;2-4, 11592383
    • Katz Y, Nadiv O, Beer Y. Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes. Arthritis Rheum 2001, 44:2176-2184. 10.1002/1529-0131(200109)44:9<2176::AID-ART371>3.0.CO;2-4, 11592383.
    • (2001) Arthritis Rheum , vol.44 , pp. 2176-2184
    • Katz, Y.1    Nadiv, O.2    Beer, Y.3
  • 33
    • 64149118092 scopus 로고    scopus 로고
    • Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes
    • 10.1016/j.molimm.2009.01.004, 19201028
    • Goldberg M, Nadiv O, Luknar-Gabor N, Agar G, Beer Y, Katz Y. Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes. Mol Immunol 2009, 46:1854-1859. 10.1016/j.molimm.2009.01.004, 19201028.
    • (2009) Mol Immunol , vol.46 , pp. 1854-1859
    • Goldberg, M.1    Nadiv, O.2    Luknar-Gabor, N.3    Agar, G.4    Beer, Y.5    Katz, Y.6
  • 34
    • 34247181323 scopus 로고    scopus 로고
    • Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: role of interleukin-17 and CD40L-CD40 interaction
    • 10.1002/art.22439, 17393416
    • Kim KW, Cho ML, Kim HR, Ju JH, Park MK, Oh HJ, Kim JS, Park SH, Lee SH, Kim HY. Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: role of interleukin-17 and CD40L-CD40 interaction. Arthritis Rheum 2007, 56:1076-1086. 10.1002/art.22439, 17393416.
    • (2007) Arthritis Rheum , vol.56 , pp. 1076-1086
    • Kim, K.W.1    Cho, M.L.2    Kim, H.R.3    Ju, J.H.4    Park, M.K.5    Oh, H.J.6    Kim, J.S.7    Park, S.H.8    Lee, S.H.9    Kim, H.Y.10
  • 35
    • 75049085147 scopus 로고    scopus 로고
    • Osteoimmunology and the effects of the immune system on bone
    • 10.1038/nrrheum.2009.217, 19884898
    • Takayanagi H. Osteoimmunology and the effects of the immune system on bone. Nat Rev Rheumatol 2009, 5:667-676. 10.1038/nrrheum.2009.217, 19884898.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 667-676
    • Takayanagi, H.1
  • 36
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
    • 10.1002/art.27334, 20131262
    • Genovese MC, Van den Bosch F, Roberson SA, Bojin S, Biagini IM, Ryan P, Sloan-Lancaster J. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum 2010, 62:929-939. 10.1002/art.27334, 20131262.
    • (2010) Arthritis Rheum , vol.62 , pp. 929-939
    • Genovese, M.C.1    Van den Bosch, F.2    Roberson, S.A.3    Bojin, S.4    Biagini, I.M.5    Ryan, P.6    Sloan-Lancaster, J.7
  • 38
    • 73249143991 scopus 로고    scopus 로고
    • A critical role of Cyr61 in interleukin-17-dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis
    • 10.1002/art.24999, 19950293
    • Zhang Q, Wu J, Cao Q, Xiao L, Wang L, He D, Ouyang G, Lin J, Shen B, Shi Y, Zhang Y, Li D, Li N. A critical role of Cyr61 in interleukin-17-dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Rheum 2009, 60:3602-3612. 10.1002/art.24999, 19950293.
    • (2009) Arthritis Rheum , vol.60 , pp. 3602-3612
    • Zhang, Q.1    Wu, J.2    Cao, Q.3    Xiao, L.4    Wang, L.5    He, D.6    Ouyang, G.7    Lin, J.8    Shen, B.9    Shi, Y.10    Zhang, Y.11    Li, D.12    Li, N.13
  • 39
    • 0036884944 scopus 로고    scopus 로고
    • Rheumatoid arthritis synoviocyte survival is dependent on Stat3
    • Krause A, Scaletta N, Ji JD, Ivashkiv LB. Rheumatoid arthritis synoviocyte survival is dependent on Stat3. J Immunol 2002, 169:6610-6616.
    • (2002) J Immunol , vol.169 , pp. 6610-6616
    • Krause, A.1    Scaletta, N.2    Ji, J.D.3    Ivashkiv, L.B.4
  • 40
    • 65449136692 scopus 로고    scopus 로고
    • Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells
    • 10.4049/jimmunol.0801882, 19265112
    • Saleh A, Shan L, Halayko AJ, Kung S, Gounni AS. Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells. J Immunol 2009, 182:3357-3365. 10.4049/jimmunol.0801882, 19265112.
    • (2009) J Immunol , vol.182 , pp. 3357-3365
    • Saleh, A.1    Shan, L.2    Halayko, A.J.3    Kung, S.4    Gounni, A.S.5
  • 41
    • 16344380754 scopus 로고    scopus 로고
    • A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells
    • 10.1073/pnas.0409894102, 555708, 15781862
    • Song H, Wang R, Wang S, Lin J. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci USA 2005, 102:4700-4705. 10.1073/pnas.0409894102, 555708, 15781862.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4700-4705
    • Song, H.1    Wang, R.2    Wang, S.3    Lin, J.4
  • 42
    • 0036232876 scopus 로고    scopus 로고
    • Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis
    • 10.1046/j.1365-2249.2002.01782.x, 1906300, 11966773
    • Kehlen A, Thiele K, Riemann D, Langner J. Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis. Clin Exp Immunol 2002, 127:539-546. 10.1046/j.1365-2249.2002.01782.x, 1906300, 11966773.
    • (2002) Clin Exp Immunol , vol.127 , pp. 539-546
    • Kehlen, A.1    Thiele, K.2    Riemann, D.3    Langner, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.