메뉴 건너뛰기




Volumn 18, Issue 38, 2012, Pages 6339-6347

Ginsenoside Rb1 directly scavenges hydroxyl radical and hypochlorous acid

Author keywords

Antioxidant; Cell free system; DNA plasmid; Ginsenoside Rb1; HOCl; Hydroxyl radical; Superoxide anion

Indexed keywords

GINSENOSIDE RB 1; HYDROGEN; HYDROXYL RADICAL; HYPOCHLOROUS ACID; PLASMID DNA; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TYROSINE;

EID: 84873958897     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212803832254     Document Type: Article
Times cited : (43)

References (63)
  • 1
    • 1342326560 scopus 로고    scopus 로고
    • Manganese complexes of curcumin analogues: Evaluation of hydroxyl radical scavenging ability, superoxide dismutase activity and stability towards hydrolysis
    • Vajragupta O, Boonchoong P, Berliner LJ. Manganese complexes of curcumin analogues: evaluation of hydroxyl radical scavenging ability, superoxide dismutase activity and stability towards hydrolysis. Free Radic Res 2004; 38(3): 303-14.
    • (2004) Free Radic Res , vol.38 , Issue.3 , pp. 303-314
    • Vajragupta, O.1    Boonchoong, P.2    Berliner, L.J.3
  • 2
    • 77953954538 scopus 로고    scopus 로고
    • Chemical and molecular mechanisms of antioxidants: Experimental approaches and model systems
    • Lü JM, Lin PH, Yao Q, Chen C. Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems. J Cell Mol Med 2010; 14(4): 840-60.
    • (2010) J Cell Mol Med , vol.14 , Issue.4 , pp. 840-860
    • Lü, J.M.1    Lin, P.H.2    Yao, Q.3    Chen, C.4
  • 3
    • 0025902273 scopus 로고
    • Endogenous mutagens and the causes of aging and cancer
    • Ames BN, Gold LS. Endogenous mutagens and the causes of aging and cancer. Mutat Res 1991; 250(1-2): 3-16.
    • (1991) Mutat Res , vol.250 , Issue.1-2 , pp. 3-16
    • Ames, B.N.1    Gold, L.S.2
  • 4
    • 0027848672 scopus 로고
    • DNA lesions, inducible DNA repair, and cell division: Three key factors in mutagenesis and carcinogenesis
    • Ames BN, Shigenaga MK, Gold LS. DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis. Environ Health Perspect 1993; 101 Suppl 5: 35-44.
    • (1993) Environ Health Perspect , vol.101 , Issue.SUPPL. 5 , pp. 35-44
    • Ames, B.N.1    Shigenaga, M.K.2    Gold, L.S.3
  • 5
    • 33745699617 scopus 로고    scopus 로고
    • Oxidative stress in autism
    • Chauhan A, Chauhan V. Oxidative stress in autism. Pathophysiology 2006; 13(3): 171-81.
    • (2006) Pathophysiology , vol.13 , Issue.3 , pp. 171-181
    • Chauhan, A.1    Chauhan, V.2
  • 6
    • 0006812769 scopus 로고
    • Potential genotoxicity of chronically elevated nitric oxide: A review
    • Liu RH, Hotchkiss JH. Potential genotoxicity of chronically elevated nitric oxide: a review. Mutat Res 1995; 339(2): 73-89.
    • (1995) Mutat Res , vol.339 , Issue.2 , pp. 73-89
    • Liu, R.H.1    Hotchkiss, J.H.2
  • 7
  • 9
    • 84858643750 scopus 로고    scopus 로고
    • Inflammasomes in carcinogenesis and anticancer immune responses
    • Zitvogel L, Kepp O, Galluzzi L, Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol 2012; 13(4): 343-51.
    • (2012) Nat Immunol , vol.13 , Issue.4 , pp. 343-351
    • Zitvogel, L.1    Kepp, O.2    Galluzzi, L.3    Kroemer, G.4
  • 10
    • 79952393266 scopus 로고    scopus 로고
    • The inflammasomes in health and disease: From genetics to molecular mechanisms of autoinflammation and beyond
    • Conforti-Andreoni C, Ricciardi-Castagnoli P, Mortellaro A. The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond. Cell Mol Immunol 2011; 8(2): 135-45.
    • (2011) Cell Mol Immunol , vol.8 , Issue.2 , pp. 135-145
    • Conforti-Andreoni, C.1    Ricciardi-Castagnoli, P.2    Mortellaro, A.3
  • 12
    • 84858630049 scopus 로고    scopus 로고
    • A role for the NLRP3 inflammasome in metabolic diseases-did Warburg miss inflammation?
    • Wen H, Ting JP, O'Neill LA. A role for the NLRP3 inflammasome in metabolic diseases-did Warburg miss inflammation? Nat Immunol 2012; 13(4): 352-7.
    • (2012) Nat Immunol , vol.13 , Issue.4 , pp. 352-357
    • Wen, H.1    Ting, J.P.2    O'Neill, L.A.3
  • 13
    • 84858677223 scopus 로고    scopus 로고
    • Sensing and reacting to microbes through the inflammasomes
    • Franchi L, Munoz-Planillo R, Nunez G. Sensing and reacting to microbes through the inflammasomes. Nat Immunol 2012; 13(4): 325-32.
    • (2012) Nat Immunol , vol.13 , Issue.4 , pp. 325-332
    • Franchi, L.1    Munoz-Planillo, R.2    Nunez, G.3
  • 14
    • 0042169046 scopus 로고    scopus 로고
    • Ginkgo biloba extracts and cancer: A research area in its infancy
    • DeFeudis FV, Papadopoulos V, Drieu K. Ginkgo biloba extracts and cancer: a research area in its infancy. Fundam Clin Pharmacol 2003; 17(4): 405-17.
    • (2003) Fundam Clin Pharmacol , vol.17 , Issue.4 , pp. 405-417
    • DeFeudis, F.V.1    Papadopoulos, V.2    Drieu, K.3
  • 15
    • 1842574410 scopus 로고    scopus 로고
    • The SU. VI. MAX Study: A randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals
    • Hercberg S, Galan P, Preziosi P, et al. The SU. VI. MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals. Arch Intern Med 2004; 164(21): 2335-42.
    • (2004) Arch Intern Med , vol.164 , Issue.21 , pp. 2335-2342
    • Hercberg, S.1    Galan, P.2    Preziosi, P.3
  • 16
    • 33144487901 scopus 로고    scopus 로고
    • Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk
    • Kirsh VA, Hayes RB, Mayne ST, et al. Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk. J Natl Cancer Inst 2006; 98(4): 245-54.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.4 , pp. 245-254
    • Kirsh, V.A.1    Hayes, R.B.2    Mayne, S.T.3
  • 17
    • 58549094920 scopus 로고    scopus 로고
    • Vitamins C and E and beta carotene supplementation and cancer risk: A randomized controlled trial
    • Lin J, Cook NR, Albert C, et al. Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial. J Natl Cancer Inst 2009; 101(1): 14-23.
    • (2009) J Natl Cancer Inst , vol.101 , Issue.1 , pp. 14-23
    • Lin, J.1    Cook, N.R.2    Albert, C.3
  • 18
    • 58149375890 scopus 로고    scopus 로고
    • Vitamins E and C in the prevention of prostate and total cancer in men: The Physicians' Health Study II randomized controlled trial
    • Gaziano JM, Glynn RJ, Christen WG, et al. Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA 2009; 301(1): 52-62.
    • (2009) JAMA , vol.301 , Issue.1 , pp. 52-62
    • Gaziano, J.M.1    Glynn, R.J.2    Christen, W.G.3
  • 19
    • 54249098684 scopus 로고    scopus 로고
    • Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs
    • Heaney ML, Gardner JR, Karasavvas N, et al. Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs. Cancer Res 2008; 68(19): 8031-8.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8031-8038
    • Heaney, M.L.1    Gardner, J.R.2    Karasavvas, N.3
  • 20
    • 69149110615 scopus 로고    scopus 로고
    • Ginseng compounds: An update on their molecular mechanisms and medical applications
    • Lü JM, Yao Q, Chen C. Ginseng compounds: an update on their molecular mechanisms and medical applications. Curr Vasc Pharmacol 2009; 7(3): 293-302.
    • (2009) Curr Vasc Pharmacol , vol.7 , Issue.3 , pp. 293-302
    • Lü, J.M.1    Yao, Q.2    Chen, C.3
  • 21
    • 0013334261 scopus 로고    scopus 로고
    • Herb sales down in mainstream market, up in natural food stores
    • Blumenthal M. Herb sales down in mainstream market, up in natural food stores. Herbalgram 2002; 55: 60.
    • (2002) Herbalgram , vol.55 , pp. 60
    • Blumenthal, M.1
  • 22
    • 13444293396 scopus 로고    scopus 로고
    • Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action
    • Cheng Y, Shen LH, Zhang JT. Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Acta Pharmacol Sin 2005; 26(2): 143-9.
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.2 , pp. 143-149
    • Cheng, Y.1    Shen, L.H.2    Zhang, J.T.3
  • 23
    • 7044233909 scopus 로고    scopus 로고
    • The nature of ginseng: Traditional use, modern research, and the question of dosage
    • Dharmananda S. The nature of ginseng: traditional use, modern research, and the question of dosage. HerbalGram 2002; 54: 34-51.
    • (2002) HerbalGram , vol.54 , pp. 34-51
    • Dharmananda, S.1
  • 24
    • 33646805400 scopus 로고    scopus 로고
    • Effects of homocysteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production
    • Ohashi R, Yan S, Mu H, et al. Effects of homocysteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production. J Surg Res 2006; 133(2): 89-94.
    • (2006) J Surg Res , vol.133 , Issue.2 , pp. 89-94
    • Ohashi, R.1    Yan, S.2    Mu, H.3
  • 25
    • 62549085553 scopus 로고    scopus 로고
    • Roles and mechanisms of human immunodeficiency virus protease inhibitor ritonavir and other anti-human immunodeficiency virus drugs in endothelial dysfunction of porcine pulmonary arteries and human pulmonary artery endothelial cells
    • Wang X, Chai H, Lin PH, Yao Q, Chen C. Roles and mechanisms of human immunodeficiency virus protease inhibitor ritonavir and other anti-human immunodeficiency virus drugs in endothelial dysfunction of porcine pulmonary arteries and human pulmonary artery endothelial cells. Am J Pathol 2009; 174(3): 771-81.
    • (2009) Am J Pathol , vol.174 , Issue.3 , pp. 771-781
    • Wang, X.1    Chai, H.2    Lin, P.H.3    Yao, Q.4    Chen, C.5
  • 26
    • 34147112444 scopus 로고    scopus 로고
    • Study on the hydroxyl radical scavenging activity changes of ginseng and ginsenoside-Rb2 by heat processing
    • Kang KS, Kim HY, Baek SH, et al. Study on the hydroxyl radical scavenging activity changes of ginseng and ginsenoside-Rb2 by heat processing. Biol Pharm Bull 2007; 30(4): 724-8.
    • (2007) Biol Pharm Bull , vol.30 , Issue.4 , pp. 724-728
    • Kang, K.S.1    Kim, H.Y.2    Baek, S.H.3
  • 27
    • 33645105351 scopus 로고    scopus 로고
    • Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs
    • Floriano-Sanchez E, Villanueva C, Medina-Campos ON, et al. Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs. Free Radic Res 2006; 40(5): 523-33.
    • (2006) Free Radic Res , vol.40 , Issue.5 , pp. 523-533
    • Floriano-Sanchez, E.1    Villanueva, C.2    Medina-Campos, O.N.3
  • 28
    • 0030273190 scopus 로고    scopus 로고
    • Hypochlorous acid and its pharmacological antagonism: An update picture
    • Lapenna D, Cuccurullo F. Hypochlorous acid and its pharmacological antagonism: an update picture. Gen Pharmacol 1996; 27(7): 1145-7.
    • (1996) Gen Pharmacol , vol.27 , Issue.7 , pp. 1145-1147
    • Lapenna, D.1    Cuccurullo, F.2
  • 29
    • 34547842123 scopus 로고    scopus 로고
    • Sallylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity
    • Medina-Campos ON, Barrera D, Segoviano-Murillo S, et al. Sallylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity. Food Chem Toxicol 2007; 45(10): 2030-9.
    • (2007) Food Chem Toxicol , vol.45 , Issue.10 , pp. 2030-2039
    • Medina-Campos, O.N.1    Barrera, D.2    Segoviano-Murillo, S.3
  • 30
    • 42749092657 scopus 로고    scopus 로고
    • Determination of hydroperoxides in foods and biological samples by the ferrous oxidation-xylenol orange method: A review of the factors that influence the method's performance
    • Bou R, Codony R, Tres A, Decker EA, Guardiola F. Determination of hydroperoxides in foods and biological samples by the ferrous oxidation-xylenol orange method: a review of the factors that influence the method's performance. Anal Biochem 2008; 377(1): 1-15.
    • (2008) Anal Biochem , vol.377 , Issue.1 , pp. 1-15
    • Bou, R.1    Codony, R.2    Tres, A.3    Decker, E.A.4    Guardiola, F.5
  • 31
    • 45849115079 scopus 로고    scopus 로고
    • Antioxidant and radical scavenging properties of curcumin
    • Ak T, Gulcin I. Antioxidant and radical scavenging properties of curcumin. Chem Biol Interact 2008; 174(1): 27-37.
    • (2008) Chem Biol Interact , vol.174 , Issue.1 , pp. 27-37
    • Ak, T.1    Gulcin, I.2
  • 32
    • 44349191658 scopus 로고    scopus 로고
    • Antioxidant and ironbinding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate
    • Dairam A, Fogel R, Daya S, Limson JL. Antioxidant and ironbinding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate. J Agric Food Chem 2008; 56(9): 3350-6.
    • (2008) J Agric Food Chem , vol.56 , Issue.9 , pp. 3350-3356
    • Dairam, A.1    Fogel, R.2    Daya, S.3    Limson, J.L.4
  • 33
    • 38749127576 scopus 로고    scopus 로고
    • Antioxidative effect of melatonin on DNA and erythrocytes against free-radical-induced oxidation
    • Zhao F, Liu ZQ, Wu D. Antioxidative effect of melatonin on DNA and erythrocytes against free-radical-induced oxidation. Chem Phys Lipids 2008; 151(2): 77-84.
    • (2008) Chem Phys Lipids , vol.151 , Issue.2 , pp. 77-84
    • Zhao, F.1    Liu, Z.Q.2    Wu, D.3
  • 34
    • 34250167926 scopus 로고    scopus 로고
    • Effects of inorganic selenium compounds on oxidative DNA damage
    • Ramoutar RR, Brumaghim JL. Effects of inorganic selenium compounds on oxidative DNA damage. J Inorg Biochem 2007; 101(7): 1028-35.
    • (2007) J Inorg Biochem , vol.101 , Issue.7 , pp. 1028-1035
    • Ramoutar, R.R.1    Brumaghim, J.L.2
  • 35
    • 0034162772 scopus 로고    scopus 로고
    • Vitamin C protects against and reverses specific hypochlorous acid-and chloramine-dependent modifications of low-density lipoprotein
    • Carr AC, Tijerina T, Frei B. Vitamin C protects against and reverses specific hypochlorous acid-and chloramine-dependent modifications of low-density lipoprotein. Biochem J 2000; 346 Pt 2: 491-9.
    • (2000) Biochem J , vol.346 , Issue.Pt 2 , pp. 491-499
    • Carr, A.C.1    Tijerina, T.2    Frei, B.3
  • 36
    • 0032213375 scopus 로고    scopus 로고
    • Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
    • Hampton MB, Kettle AJ, Winterbourn CC. Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 1998; 92(9): 3007-17.
    • (1998) Blood , vol.92 , Issue.9 , pp. 3007-3017
    • Hampton, M.B.1    Kettle, A.J.2    Winterbourn, C.C.3
  • 37
    • 33749986298 scopus 로고    scopus 로고
    • Free radicals and antioxidants in normal physiological functions and human disease
    • Valko M, Leibfritz D, Moncol J, et al. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007; 39(1): 44-84.
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.1 , pp. 44-84
    • Valko, M.1    Leibfritz, D.2    Moncol, J.3
  • 38
    • 0033964202 scopus 로고    scopus 로고
    • Structure-Reactivity Based Estimation of the Rate Constants for Hydroxyl Radical Reactions with Hydrocarbons
    • Neeb P. Structure-Reactivity Based Estimation of the Rate Constants for Hydroxyl Radical Reactions with Hydrocarbons. J Atmospheric Chem 2000; 35: 295-315.
    • (2000) J Atmospheric Chem , vol.35 , pp. 295-315
    • Neeb, P.1
  • 39
    • 33746561383 scopus 로고    scopus 로고
    • Novel hydroxyl radical scavenging antioxidant activity assay for watersoluble antioxidants using a modified CUPRAC method
    • Bektasoglu B, Esin Celik S, Ozyurek M, Guclu K, Apak R. Novel hydroxyl radical scavenging antioxidant activity assay for watersoluble antioxidants using a modified CUPRAC method. Biochem Biophys Res Commun 2006; 345(3): 1194-200.
    • (2006) Biochem Biophys Res Commun , vol.345 , Issue.3 , pp. 1194-1200
    • Bektasoglu, B.1    Esin Celik, S.2    Ozyurek, M.3    Guclu, K.4    Apak, R.5
  • 40
    • 0017821465 scopus 로고
    • Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions
    • Cederbaum AI, Dicker E, Cohen G. Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions. Biochemistry 1978; 17(15): 3058-64.
    • (1978) Biochemistry , vol.17 , Issue.15 , pp. 3058-3064
    • Cederbaum, A.I.1    Dicker, E.2    Cohen, G.3
  • 41
    • 57749111966 scopus 로고    scopus 로고
    • Relevance of the capacity of phosphorylated fructose to scavenge the hydroxyl radical
    • Spasojevic I, Mojovic M, Blagojevic D, et al. Relevance of the capacity of phosphorylated fructose to scavenge the hydroxyl radical. Carbohydr Res 2009; 344(1): 80-4.
    • (2009) Carbohydr Res , vol.344 , Issue.1 , pp. 80-84
    • Spasojevic, I.1    Mojovic, M.2    Blagojevic, D.3
  • 42
    • 34248221485 scopus 로고    scopus 로고
    • ESR study on the structure and hydroxyl radical-scavenging activity relationships of ginsenosides isolated from Panax ginseng C A Meyer
    • Kang KS, Yokozawa T, Yamabe N, Kim HY, Park JH. ESR study on the structure and hydroxyl radical-scavenging activity relationships of ginsenosides isolated from Panax ginseng C A Meyer. Biol Pharm Bull 2007; 30(5): 917-21.
    • (2007) Biol Pharm Bull , vol.30 , Issue.5 , pp. 917-921
    • Kang, K.S.1    Yokozawa, T.2    Yamabe, N.3    Kim, H.Y.4    Park, J.H.5
  • 43
    • 41949124779 scopus 로고    scopus 로고
    • The role of selenium in chronic disease
    • Boosalis MG. The role of selenium in chronic disease. Nutr Clin Pract 2008; 23(2): 152-60.
    • (2008) Nutr Clin Pract , vol.23 , Issue.2 , pp. 152-160
    • Boosalis, M.G.1
  • 44
    • 56349145629 scopus 로고    scopus 로고
    • Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study
    • Schnabel R, Lubos E, Messow CM, et al. Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study. Am Heart J 2008; 156(6): 1201 e1-11.
    • (2008) Am Heart J , vol.156 , Issue.6
    • Schnabel, R.1    Lubos, E.2    Messow, C.M.3
  • 45
    • 53849111214 scopus 로고    scopus 로고
    • Mass spectrometric analysis of HOCl-and free-radical-induced damage to lipids and proteins
    • Pitt AR, Spickett CM. Mass spectrometric analysis of HOCl-and free-radical-induced damage to lipids and proteins. Biochem Soc Trans 2008; 36(Pt 5): 1077-82.
    • (2008) Biochem Soc Trans , vol.36 , Issue.Pt 5 , pp. 1077-1082
    • Pitt, A.R.1    Spickett, C.M.2
  • 46
    • 33646788424 scopus 로고    scopus 로고
    • Nitrotyrosine and chlorotyrosine: Clinical significance and biological functions in the vascular system
    • Mohiuddin I, Chai H, Lin PH, et al. Nitrotyrosine and chlorotyrosine: clinical significance and biological functions in the vascular system. J Surg Res 2006; 133(2): 143-9.
    • (2006) J Surg Res , vol.133 , Issue.2 , pp. 143-149
    • Mohiuddin, I.1    Chai, H.2    Lin, P.H.3
  • 47
    • 0024316073 scopus 로고
    • Different selectivities of oxidants during oxidation of methionine residues in the alpha-1-proteinase inhibitor
    • Maier KL, Matejkova E, Hinze H, et al. Different selectivities of oxidants during oxidation of methionine residues in the alpha-1-proteinase inhibitor. FEBS Lett 1989; 250(2): 221-6.
    • (1989) FEBS Lett , vol.250 , Issue.2 , pp. 221-226
    • Maier, K.L.1    Matejkova, E.2    Hinze, H.3
  • 48
    • 2942636087 scopus 로고    scopus 로고
    • Determination of polyacetylenes and ginsenosides in Panax species using high performance liquid chromatography
    • Washida D, Kitanaka S. Determination of polyacetylenes and ginsenosides in Panax species using high performance liquid chromatography. Chem Pharm Bull 2003; 51(11): 1314-7.
    • (2003) Chem Pharm Bull , vol.51 , Issue.11 , pp. 1314-1317
    • Washida, D.1    Kitanaka, S.2
  • 49
    • 0037296911 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats
    • Xu QF, Fang XL, Chen DF. Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats. J Ethnopharmacol 2003; 84(2-3): 187-92.
    • (2003) J Ethnopharmacol , vol.84 , Issue.2-3 , pp. 187-192
    • Xu, Q.F.1    Fang, X.L.2    Chen, D.F.3
  • 50
    • 38649129855 scopus 로고    scopus 로고
    • Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway
    • Lau WS, Chan RY, Guo DA, Wong MS. Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway. J Steroid Biochem Mol Biol 2008; 108(1-2): 64-71.
    • (2008) J Steroid Biochem Mol Biol , vol.108 , Issue.1-2 , pp. 64-71
    • Lau, W.S.1    Chan, R.Y.2    Guo, D.A.3    Wong, M.S.4
  • 51
    • 34948887630 scopus 로고    scopus 로고
    • Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor
    • Leung KW, Cheung LW, Pon YL, et al. Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor. Br J Pharmacol 2007; 152(2): 207-15.
    • (2007) Br J Pharmacol , vol.152 , Issue.2 , pp. 207-215
    • Leung, K.W.1    Cheung, L.W.2    Pon, Y.L.3
  • 52
    • 65349185491 scopus 로고    scopus 로고
    • Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells
    • Leung KW, Leung FP, Mak NK, et al. Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol 2009; 156(4): 626-37.
    • (2009) Br J Pharmacol , vol.156 , Issue.4 , pp. 626-637
    • Leung, K.W.1    Leung, F.P.2    Mak, N.K.3
  • 53
    • 34948814000 scopus 로고    scopus 로고
    • A ginseng-derived oestrogen receptor beta (ERbeta) agonist, Rb1 ginsenoside, attenuates capillary morphogenesis
    • Papapetropoulos A. A ginseng-derived oestrogen receptor beta (ERbeta) agonist, Rb1 ginsenoside, attenuates capillary morphogenesis. Br J Pharmacol 2007; 152(2): 172-4.
    • (2007) Br J Pharmacol , vol.152 , Issue.2 , pp. 172-174
    • Papapetropoulos, A.1
  • 54
    • 34248590312 scopus 로고    scopus 로고
    • Nongenomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor
    • Leung KW, Leung FP, Huang Y, Mak NK, Wong RN. Nongenomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor. FEBS Lett 2007; 581(13): 2423-8.
    • (2007) FEBS Lett , vol.581 , Issue.13 , pp. 2423-2428
    • Leung, K.W.1    Leung, F.P.2    Huang, Y.3    Mak, N.K.4    Wong, R.N.5
  • 55
    • 33845982523 scopus 로고    scopus 로고
    • Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: A possible involvement of androgen receptor
    • Yu J, Eto M, Akishita M, et al. Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: a possible involvement of androgen receptor. Biochem Biophys Res Commun 2007; 353(3): 764-9.
    • (2007) Biochem Biophys Res Commun , vol.353 , Issue.3 , pp. 764-769
    • Yu, J.1    Eto, M.2    Akishita, M.3
  • 56
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epitheliumderived factor: A potent inhibitor of angiogenesis
    • Dawson DW, Volpert OV, Gillis P, et al. Pigment epitheliumderived factor: a potent inhibitor of angiogenesis. Science 1999; 285(5425): 245-8.
    • (1999) Science , vol.285 , Issue.5425 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3
  • 57
    • 36649003694 scopus 로고    scopus 로고
    • PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells
    • Ho TC, Chen SL, Yang YC, Liao CL, Cheng HC, Tsao YP. PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells. Cardiovasc Res 2007; 76(2): 213-23.
    • (2007) Cardiovasc Res , vol.76 , Issue.2 , pp. 213-223
    • Ho, T.C.1    Chen, S.L.2    Yang, Y.C.3    Liao, C.L.4    Cheng, H.C.5    Tsao, Y.P.6
  • 58
    • 2342566543 scopus 로고    scopus 로고
    • Inhibition of glioma invasion by overexpression of pigment epitheliumderived factor
    • Guan M, Pang CP, Yam HF, Cheung KF, Liu WW, Lu Y. Inhibition of glioma invasion by overexpression of pigment epitheliumderived factor. Cancer Gene Ther 2004; 11(5): 325-32.
    • (2004) Cancer Gene Ther , vol.11 , Issue.5 , pp. 325-332
    • Guan, M.1    Pang, C.P.2    Yam, H.F.3    Cheung, K.F.4    Liu, W.W.5    Lu, Y.6
  • 59
    • 0025772716 scopus 로고
    • PEDF: A pigment epithelium-derived factor with potent neuronal differentiative activity
    • Tombran-Tink J, Chader GG, Johnson LV. PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity. Exp Eye Res 1991; 53(3): 411-4.
    • (1991) Exp Eye Res , vol.53 , Issue.3 , pp. 411-414
    • Tombran-Tink, J.1    Chader, G.G.2    Johnson, L.V.3
  • 60
    • 18844457413 scopus 로고    scopus 로고
    • Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries
    • Zhou W, Chai H, Lin PH, Lumsden AB, Yao Q, Chen C. Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. J Vasc Surg 2005; 41(5): 861-8.
    • (2005) J Vasc Surg , vol.41 , Issue.5 , pp. 861-868
    • Zhou, W.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 61
    • 24144432810 scopus 로고    scopus 로고
    • Effects of 5 HIV protease inhibitors on vasomotor function and superoxide anion production in porcine coronary arteries
    • Chai H, Yang H, Yan S, et al. Effects of 5 HIV protease inhibitors on vasomotor function and superoxide anion production in porcine coronary arteries. J Acquir Immune Defic Syndr 2005; 40(1): 12-9.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , Issue.1 , pp. 12-19
    • Chai, H.1    Yang, H.2    Yan, S.3
  • 62
    • 54049156519 scopus 로고    scopus 로고
    • Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells
    • Chen C, Chai H, Wang X, et al. Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells. Blood 2008; 112(8): 3205-16.
    • (2008) Blood , vol.112 , Issue.8 , pp. 3205-3216
    • Chen, C.1    Chai, H.2    Wang, X.3
  • 63
    • 77953788470 scopus 로고    scopus 로고
    • Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells
    • Chen C, Jiang J, Lü JM, et al. Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells. Am J Physiol Heart Circ Physiol 2010; 299(1): H193-201.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , Issue.1
    • Chen, C.1    Jiang, J.2    Lü, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.