Dysfunctional Activation of Neurotensin/IL-8 Pathway in Hepatocellular Carcinoma Is Associated with Increased Inflammatory Response in Microenvironment, More Epithelial Mesenchymal Transition in Cancer and Worse Prognosis in Patients

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Yu, Jinpu ^a   Ren, Xiubao ^a   Chen, Yongzi ^a   Liu, Pengpeng ^a   Wei, Xiyin ^a   Li, Hui ^a   Ying, Guoguang ^a   Chen, Kexin ^a   Winkler, Hans ^a   Hao, Xishan ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CD68 ANTIGEN; GELATINASE B; INTERLEUKIN 8; NEUROTENSIN; UVOMORULIN; VASCULOTROPIN; VIMENTIN;

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER PROGNOSIS; CANCER SURVIVAL; CANCER TISSUE; CELL INFILTRATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER SURGERY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; TUMOR MICROENVIRONMENT; UPREGULATION;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CLUSTER ANALYSIS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-8; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEUROTENSIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TUMOR MICROENVIRONMENT;

EID: 84873935535     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056069     Document Type: Article

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