Mutation in E1, the Ubiquitin Activating Enzyme, Reduces Drosophila Lifespan and Results in Motor Impairment

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Liu, Hsiu Yu ^a   Pfleger, Cathie M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN E1; RAS PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DROSOPHILA; GENE DOSAGE; GENE E1; GENE FUNCTION; GENE IDENTIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GENOTYPING TECHNIQUE; GROWTH INHIBITION; HETEROZYGOSITY LOSS; HOMOZYGOSITY; LIFESPAN; MOLECULAR PATHOLOGY; MORTALITY; MOTOR DYSFUNCTION; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; UPREGULATION; WILD TYPE;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENETIC DISEASES, X-LINKED; HUMANS; LONGEVITY; MOTOR ACTIVITY; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; SPINAL MUSCULAR ATROPHIES OF CHILDHOOD; UBIQUITIN-ACTIVATING ENZYMES;

EID: 84873865668     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032835     Document Type: Article

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