Brain Region Specific Pre-Synaptic and Post-Synaptic Degeneration Are Early Components of Neuropathology in Prion Disease

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Šišková, Zuzana ^a,b   Reynolds, Richard A ^a   O'Connor, Vincent ^a   Perry, V Hugh ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BRAIN DEGENERATION; BRAIN REGION; CONTROLLED STUDY; DENDRITIC SPINE; DISEASE SEVERITY; ELECTRON MICROSCOPY; FEMALE; IMMUNOCYTOCHEMISTRY; MOUSE; NERVE CELL DEGENERATION; NEUROPATHOLOGY; NONHUMAN; POSTSYNAPTIC DENSITY; POSTSYNAPTIC POTENTIAL; PRESYNAPTIC POTENTIAL; PRION DISEASE; PROTEIN FOLDING; PURKINJE CELL; STRATUM RADIATUM; TARGET CELL;

ANIMALS; BRAIN; CA1 REGION, HIPPOCAMPAL; DENDRITES; FEMALE; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON; ORGAN SPECIFICITY; PRION DISEASES; PURKINJE CELLS; SYNAPSES; TIME FACTORS;

EID: 84873810299     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055004     Document Type: Article

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