Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

EMBO Journal

Volumn 29, Issue 14, 2010, Pages 2446-2460

  Shiwaku, Hiroki ^a   Yoshimura, Natsue ^a   Tamura, Takuya ^a   Sone, Masaki ^a   Ogishima, Soichi ^b   Watase, Kei ^a   Tagawa, Kazuhiko ^a   Okazawa, Hitoshi ^a,c  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

ataxin 1; Bergmann glia; Maxer; non cell autonomous pathology; SCA1

Indexed keywords

ATAXIN 1; CDK5RAP3 PROTEIN; CYCLIN D1; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMIC ACID; MAXER PROTEIN; MEMBRANE PROTEIN; MUTANT PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BERGMANN GLIA LAYER; CELL CYCLE G1 PHASE; CELL NUCLEUS; CELL PROLIFERATION; CEREBELLUM; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EMBRYO; ENDOPLASMIC RETICULUM; GENE REPRESSION; GLIA; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PURKINJE CELL; RAT; SPINOCEREBELLAR DEGENERATION;

AMINO ACID SEQUENCE; ANIMALS; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; EXCITATORY AMINO ACID TRANSPORTER 1; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEUROGLIA; NUCLEAR PROTEINS; RATS; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; TISSUE DISTRIBUTION;

MUS;

EID: 77954887500     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.116     Document Type: Article

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