-
1
-
-
0021858660
-
Purine nucleotide metabolism in resident and activated rat macrophages in vitro
-
Barankiewicz J, Cohen A (1985) Purine nucleotide metabolism in resident and activated rat macrophages in vitro. Eur J Immunol 15: 627-631.
-
(1985)
Eur J Immunol
, vol.15
, pp. 627-631
-
-
Barankiewicz, J.1
Cohen, A.2
-
2
-
-
0037230080
-
Inosine reduces inflammation and improves survival in a murine model of colitis
-
Mabley JG, Pacher P, Liaudet L, Soriano FG, Haskó G, Marton A, Szabo C, Salzman AL (2003) Inosine reduces inflammation and improves survival in a murine model of colitis. Am J Physiol Gastrointest Liver Physiol 284: 138-144.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
, pp. 138-144
-
-
Mabley, J.G.1
Pacher, P.2
Liaudet, L.3
Soriano, F.G.4
Haskó, G.5
Marton, A.6
Szabo, C.7
Salzman, A.L.8
-
3
-
-
0038689146
-
Adenosine in the spinal cord and periphery: release and regulation of pain
-
Sawynok J, Liu XJ (2003) Adenosine in the spinal cord and periphery: release and regulation of pain. Prog Neurobiol 69: 313-340.
-
(2003)
Prog Neurobiol
, vol.69
, pp. 313-340
-
-
Sawynok, J.1
Liu, X.J.2
-
4
-
-
1342264245
-
Immunomodulatory and neuroprotective effects of inosine
-
Hasko G, Sitkovsky MV, Szabó C (2004) Immunomodulatory and neuroprotective effects of inosine. Trends Pharmacol Sci 25: 152-157.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 152-157
-
-
Hasko, G.1
Sitkovsky, M.V.2
Szabó, C.3
-
5
-
-
0020997937
-
Inosine: a naturally occurring cardiotonic agent
-
Aviado DM (1983) Inosine: a naturally occurring cardiotonic agent. J Pharmacol 4: 47-71.
-
(1983)
J Pharmacol
, vol.4
, pp. 47-71
-
-
Aviado, D.M.1
-
6
-
-
0017753804
-
Positive inotropic response to inosine in the in situ canine heart
-
Jones CE, Thomas JX Jr, Devous MD, Norris CP, Smith EE (1977) Positive inotropic response to inosine in the in situ canine heart. Am J Physiol 233: 438-443.
-
(1977)
Am J Physiol
, vol.233
, pp. 438-443
-
-
Jones, C.E.1
Thomas Jr., J.X.2
Devous, M.D.3
Norris, C.P.4
Smith, E.E.5
-
7
-
-
0025329239
-
Hemodynamic effects of inosine in combination with positive and negative inotropic drugs: studies on rats in vivo
-
Seesko RC, Zimmer GH (1990) Hemodynamic effects of inosine in combination with positive and negative inotropic drugs: studies on rats in vivo. J Cardiovasc Pharmacol 16: 249-256.
-
(1990)
J Cardiovasc Pharmacol
, vol.16
, pp. 249-256
-
-
Seesko, R.C.1
Zimmer, G.H.2
-
8
-
-
0344305461
-
Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo
-
Gomez G, Sitkovsky MV (2003) Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo. Blood 102: 4472-4478.
-
(2003)
Blood
, vol.102
, pp. 4472-4478
-
-
Gomez, G.1
Sitkovsky, M.V.2
-
9
-
-
0035053867
-
Inosine improves gut permeability and vascular reactivity in endotoxic shock
-
Garcia Soriano F, Liaudet L, Marton A, Haskó G, Batista Lorigados C, Deitch EA, Szabó C (2001) Inosine improves gut permeability and vascular reactivity in endotoxic shock. Crit Care Med 29: 703-708.
-
(2001)
Crit Care Med
, vol.29
, pp. 703-708
-
-
Garcia Soriano, F.1
Liaudet, L.2
Marton, A.3
Haskó, G.4
Batista Lorigados, C.5
Deitch, E.A.6
Szabó, C.7
-
10
-
-
0035653502
-
Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro
-
Marton A, Pacher P, Murthy KG, Németh ZH, Haskó G, Szabó C (2001) Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro. Int J Mol Med 8: 617-621.
-
(2001)
Int J Mol Med
, vol.8
, pp. 617-621
-
-
Marton, A.1
Pacher, P.2
Murthy, K.G.3
Németh, Z.H.4
Haskó, G.5
Szabó, C.6
-
11
-
-
77954907719
-
Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways
-
Nascimento FP, Figueredo SM, Marcon R, Martins DF, Macedo SJ Jr, Lima DAN, Almeida RC, Ostroski RM, Rodrigues ALS, Santos ARS (2010) Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways. J Pharmacol Exp Ther 334: 590-598.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 590-598
-
-
Nascimento, F.P.1
Figueredo, S.M.2
Marcon, R.3
Martins, D.F.4
Macedo Jr., S.J.5
Lima, D.A.N.6
Almeida, R.C.7
Ostroski, R.M.8
Rodrigues, A.L.S.9
Santos, A.R.S.10
-
12
-
-
34250719722
-
Purine and pyrimidine receptors
-
Burnstock G (2007) Purine and pyrimidine receptors. Cell Mol Life Sci 64: 1471-1483.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1471-1483
-
-
Burnstock, G.1
-
13
-
-
33644770260
-
Adenosine receptors as therapeutic targets
-
Jacobson KA, Gao GZ (2006) Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 5: 247-264.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 247-264
-
-
Jacobson, K.A.1
Gao, G.Z.2
-
14
-
-
0032540196
-
Adenosine receptor activation and nociception
-
Sawynok J (1998) Adenosine receptor activation and nociception. Eur J Pharmacol 347: 1-11.
-
(1998)
Eur J Pharmacol
, vol.347
, pp. 1-11
-
-
Sawynok, J.1
-
15
-
-
47349125085
-
Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders
-
Cunha RA, Ferre S, Vaugeois JM, Chen JF (2008) Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders. Curr Pharm Des 14: 1512-1524.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 1512-1524
-
-
Cunha, R.A.1
Ferre, S.2
Vaugeois, J.M.3
Chen, J.F.4
-
16
-
-
0038143146
-
Pharmacology of adenosine A2A receptors and therapeutic applications
-
Fredholm BB, Cunha RA, Svenningsson P (2003) Pharmacology of adenosine A2A receptors and therapeutic applications. Curr Top Med Chem 3: 413-426.
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 413-426
-
-
Fredholm, B.B.1
Cunha, R.A.2
Svenningsson, P.3
-
17
-
-
0024730134
-
Drug receptors and the inhibition of nerve cells
-
North RA (1989) Drug receptors and the inhibition of nerve cells. Br J Pharmacol 98: 13-28.
-
(1989)
Br J Pharmacol
, vol.98
, pp. 13-28
-
-
North, R.A.1
-
18
-
-
74549121505
-
v3.2 T-type channels revisited
-
v3. 2 T-type channels revisited. Mol Pharmacol 77: 136-138.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 136-138
-
-
Perez-Reyes, E.1
-
19
-
-
0032104054
-
Modulation of voltage-dependent calcium channels by G proteins
-
Zamponi GW, Snutch TP (1998) Modulation of voltage-dependent calcium channels by G proteins. Curr Opin Neurobiol 8: 351-356.
-
(1998)
Curr Opin Neurobiol
, vol.8
, pp. 351-356
-
-
Zamponi, G.W.1
Snutch, T.P.2
-
20
-
-
0018956018
-
Intrathecal morphine in mice. A new technique
-
Hylden JL, Wilcox GL (1980) Intrathecal morphine in mice. A new technique. Eur J Pharmacol 67: 313-316.
-
(1980)
Eur J Pharmacol
, vol.67
, pp. 313-316
-
-
Hylden, J.L.1
Wilcox, G.L.2
-
21
-
-
0021846807
-
Formalin test in mice, a useful technique for evaluating mild analgesics
-
Hunskaar S, Fasmer OB, Hole K (1985) Formalin test in mice, a useful technique for evaluating mild analgesics. J Neurosci Methods 14: 69-76.
-
(1985)
J Neurosci Methods
, vol.14
, pp. 69-76
-
-
Hunskaar, S.1
Fasmer, O.B.2
Hole, K.3
-
23
-
-
50349089097
-
Additive interaction between peripheral and central mechanisms involved in the antinociceptive effect of diclofenac in the formalin test in rats
-
Ortiz MI, Lozano-Cuenca J, Granados-Soto V, Castañeda-Hernández G (2008) Additive interaction between peripheral and central mechanisms involved in the antinociceptive effect of diclofenac in the formalin test in rats. Pharmacol Biochem Behav 91: 32-37.
-
(2008)
Pharmacol Biochem Behav
, vol.91
, pp. 32-37
-
-
Ortiz, M.I.1
Lozano-Cuenca, J.2
Granados-Soto, V.3
Castañeda-Hernández, G.4
-
24
-
-
0023874505
-
Pertussis toxin inhibits antinociception produced by intrathecal injection of morphine, noradrenaline and baclofen
-
Hoehn K, Reid A, Sawynok J (1988) Pertussis toxin inhibits antinociception produced by intrathecal injection of morphine, noradrenaline and baclofen. Eur J Pharmacol 146: 65-72.
-
(1988)
Eur J Pharmacol
, vol.146
, pp. 65-72
-
-
Hoehn, K.1
Reid, A.2
Sawynok, J.3
-
25
-
-
0028179209
-
Interaction of delta-opioid receptors with multiple G proteins: a non-relationship between agonist potency to inhibit adenylyl cyclase and to activate G proteins
-
Prather PL, Loh HH, Law PY (1994) Interaction of delta-opioid receptors with multiple G proteins: a non-relationship between agonist potency to inhibit adenylyl cyclase and to activate G proteins. Mol Pharmacol 45: 997-1003.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 997-1003
-
-
Prather, P.L.1
Loh, H.H.2
Law, P.Y.3
-
26
-
-
0030902326
-
The effects of recombinant rat mu-opioid receptor activation in CHO cells on phospholipase C, [Ca2+]i and adenylyl cyclase
-
Smart D, Hirst RA, Hirota K, Grand DK, Lambert DG (1997) The effects of recombinant rat mu-opioid receptor activation in CHO cells on phospholipase C, [Ca2+]i and adenylyl cyclase. Br J Pharmacol 120: 1165-1171.
-
(1997)
Br J Pharmacol
, vol.120
, pp. 1165-1171
-
-
Smart, D.1
Hirst, R.A.2
Hirota, K.3
Grand, D.K.4
Lambert, D.G.5
-
27
-
-
0033979607
-
The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels
-
Rodrigues AR, Duarte ID (2000) The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels. Br J Pharmacol 129: 110-114.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 110-114
-
-
Rodrigues, A.R.1
Duarte, I.D.2
-
28
-
-
0021814366
-
Pertussis toxin reverses adenosine inhibition of neuronal glutamate release
-
Dolphin AC, Prestwich SA (1985) Pertussis toxin reverses adenosine inhibition of neuronal glutamate release. Nature 316: 148-150.
-
(1985)
Nature
, vol.316
, pp. 148-150
-
-
Dolphin, A.C.1
Prestwich, S.A.2
-
29
-
-
4644237028
-
Potassium channels and pain: present realities and future opportunities
-
Ocaña M, Cendán CM, Cobos EJ, Entrena JM, Baeyens JM (2004) Potassium channels and pain: present realities and future opportunities. Eur J Pharmacol 500: 203-219.
-
(2004)
Eur J Pharmacol
, vol.500
, pp. 203-219
-
-
Ocaña, M.1
Cendán, C.M.2
Cobos, E.J.3
Entrena, J.M.4
Baeyens, J.M.5
-
31
-
-
0028178741
-
Role of ATP-sensitive K+ channels in antinociception induced by R-PIA, an adenosine A1 receptor agonist
-
Ocaña M, Baeyens JM (1994) Role of ATP-sensitive K+ channels in antinociception induced by R-PIA, an adenosine A1 receptor agonist. Naunyn Schmiedebergs Arch pharmacol 350: 57-62.
-
(1994)
Naunyn Schmiedebergs Arch Pharmacol
, vol.350
, pp. 57-62
-
-
Ocaña, M.1
Baeyens, J.M.2
-
33
-
-
10744231787
-
International Union of Pharmacology: XLI. Compendium of voltage-gated ion channels: potassium channels
-
Gutman GA, Chandy KG, Aldeman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, Kuperschmidt S, Kurachi Y, Lazdunski M, Lesage F, Lester HA, McKinnon D, Nichols CG, O'Kelly I, Robbins J, Robertson GA, Rudy B, Sanguinetti M, Seino S, Stuehmer W, Tamkun MM, Vandenberg CA, Wei A, Wulff H, Wymore RS (2003) International Union of Pharmacology: XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev 55: 583-586.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 583-586
-
-
Gutman, G.A.1
Chandy, K.G.2
Aldeman, J.P.3
Aiyar, J.4
Bayliss, D.A.5
Clapham, D.E.6
Covarriubias, M.7
Desir, G.V.8
Furuichi, K.9
Ganetzky, B.10
Garcia, M.L.11
Grissmer, S.12
Jan, L.Y.13
Karschin, A.14
Kim, D.15
Kuperschmidt, S.16
Kurachi, Y.17
Lazdunski, M.18
Lesage, F.19
Lester, H.A.20
McKinnon, D.21
Nichols, C.G.22
O'Kelly, I.23
Robbins, J.24
Robertson, G.A.25
Rudy, B.26
Sanguinetti, M.27
Seino, S.28
Stuehmer, W.29
Tamkun, M.M.30
Vandenberg, C.A.31
Wei, A.32
Wulff, H.33
Wymore, R.S.34
more..
-
35
-
-
12344311440
-
Involvement of potassium channels and nitric oxide in tramadol antinociception
-
Yalcin I, Asku F (2005) Involvement of potassium channels and nitric oxide in tramadol antinociception. Pharmacol Biochem Behav 80: 69-75.
-
(2005)
Pharmacol Biochem Behav
, vol.80
, pp. 69-75
-
-
Yalcin, I.1
Asku, F.2
-
36
-
-
0036497248
-
Pharmacological evidence for the activation of K+ channels by diclofenac
-
Ortiz MI, Torres-López JE, Castañeda-Hernández G, Rosas R, Vidal-Cantú GC, Granados-Soto V (2002) Pharmacological evidence for the activation of K+ channels by diclofenac. Eur J Pharmacol 438: 85-91.
-
(2002)
Eur J Pharmacol
, vol.438
, pp. 85-91
-
-
Ortiz, M.I.1
Torres-López, J.E.2
Castañeda-Hernández, G.3
Rosas, R.4
Vidal-Cantú, G.C.5
Granados-Soto, V.6
-
37
-
-
0035943412
-
Participation of the nitric oxide-cyclic GMP-ATP-sensitive K+ channel pathway in the antinociceptive action of ketorolac
-
Lázaro-Ibáñez GG, Torres-López JE, Granados-Soto V (2001) Participation of the nitric oxide-cyclic GMP-ATP-sensitive K+ channel pathway in the antinociceptive action of ketorolac. Eur J Pharmacol 426: 39-44.
-
(2001)
Eur J Pharmacol
, vol.426
, pp. 39-44
-
-
Lázaro-Ibáñez, G.G.1
Torres-López, J.E.2
Granados-Soto, V.3
-
38
-
-
0037165824
-
Involvement of ATP-sensitive K+ channels in the peripheral antinociceptive effect induced by dipyrone
-
Alves D, Duarte I (2002) Involvement of ATP-sensitive K+ channels in the peripheral antinociceptive effect induced by dipyrone. Eur J Pharmacol 444: 47-52.
-
(2002)
Eur J Pharmacol
, vol.444
, pp. 47-52
-
-
Alves, D.1
Duarte, I.2
-
39
-
-
1642304125
-
The NOcGMP-K+ channel pathway participates in the antinociceptive effect of diclofenac, but not of indomethacin
-
Ortiz MI, Granados-Soto V, Castañeda-Hernández G (2003) The NOcGMP-K+ channel pathway participates in the antinociceptive effect of diclofenac, but not of indomethacin. Pharmacol Biochem Behav 76: 187-195.
-
(2003)
Pharmacol Biochem Behav
, vol.76
, pp. 187-195
-
-
Ortiz, M.I.1
Granados-Soto, V.2
Castañeda-Hernández, G.3
-
40
-
-
1642464885
-
Participation of the l-arginine-nitric oxide-cyclic GMP-ATP-sensitive K+ channel cascade in the antinociceptive effect of rofecoxib
-
Déciga-Campos M, López-Muñoz FJ (2004) Participation of the l-arginine-nitric oxide-cyclic GMP-ATP-sensitive K+ channel cascade in the antinociceptive effect of rofecoxib. Eur J Pharmacol 484: 193-199.
-
(2004)
Eur J Pharmacol
, vol.484
, pp. 193-199
-
-
Déciga-Campos, M.1
López-Muñoz, F.J.2
-
41
-
-
0034857265
-
Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw
-
Soares AC, Duarte ID (2001) Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw. Br J Pharmacol 134: 127-131.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 127-131
-
-
Soares, A.C.1
Duarte, I.D.2
-
42
-
-
0024829523
-
Charybdotoxin inhibits proliferation and interleukin 2 production in human peripheral blood lymphocytes
-
Price M, Lee SC, Deutsch C (1989) Charybdotoxin inhibits proliferation and interleukin 2 production in human peripheral blood lymphocytes. Proc Natl Acad Sci 86: 10171-10175.
-
(1989)
Proc Natl Acad Sci
, vol.86
, pp. 10171-10175
-
-
Price, M.1
Lee, S.C.2
Deutsch, C.3
-
44
-
-
0035892242
-
Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release
-
Hu H, Shao LR, Chavoshy S et al (2001) Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release. J Neurosci 21: 9585-9597.
-
(2001)
J Neurosci
, vol.21
, pp. 9585-9597
-
-
Hu, H.1
Shao, L.R.2
Chavoshy, S.3
-
45
-
-
11444270017
-
Voltage-gated calcium channels as targets for the treatment of chronic pain
-
McGivern JG, McDonough SI (2004) Voltage-gated calcium channels as targets for the treatment of chronic pain. Curr Drug Targets CNS Neurol Disord 3: 457-478.
-
(2004)
Curr Drug Targets CNS Neurol Disord
, vol.3
, pp. 457-478
-
-
McGivern, J.G.1
McDonough, S.I.2
-
46
-
-
0033969834
-
Effects of antagonists to high-threshold calcium channels upon spinal mechanisms of pain, hyperalgesia and allodynia
-
Vanegas H, Schaible H (2000) Effects of antagonists to high-threshold calcium channels upon spinal mechanisms of pain, hyperalgesia and allodynia. Pain 85: 9-18.
-
(2000)
Pain
, vol.85
, pp. 9-18
-
-
Vanegas, H.1
Schaible, H.2
-
47
-
-
30844473761
-
Calcium channels as therapeutic targets in neuropathic pain
-
Yaksh TL (2006) Calcium channels as therapeutic targets in neuropathic pain. J Pain 7: S13-S30.
-
(2006)
J Pain
, vol.7
-
-
Yaksh, T.L.1
-
48
-
-
0035004412
-
Involvement of calcium in pain and antinociception
-
Prado WA (2001) Involvement of calcium in pain and antinociception. Braz J Med Biol Res 34: 449-461.
-
(2001)
Braz J Med Biol Res
, vol.34
, pp. 449-461
-
-
Prado, W.A.1
-
49
-
-
0345307677
-
Role of ions channels in mechanisms controlling gastrointestinal pain pathways
-
Cervero F, Laird JMA (2003) Role of ions channels in mechanisms controlling gastrointestinal pain pathways. Curr Opin Pharmacol 3: 608-612.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 608-612
-
-
Cervero, F.1
Laird, J.M.A.2
-
50
-
-
1442277007
-
Calcium receptor-mediated intracellular signalling
-
Ward DT (2004) Calcium receptor-mediated intracellular signalling. Cell Calcium 35: 217-228.
-
(2004)
Cell Calcium
, vol.35
, pp. 217-228
-
-
Ward, D.T.1
|