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Volumn 1, Issue 4, 2012, Pages 322-332

Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells

Author keywords

Cancer stem cells; Gene transfer; Glioma; Herpes simplex virus; Hypoxia

Indexed keywords

CD133 ANTIGEN; ONCOLYTIC VIRUS;

EID: 84873739787     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2011-0035     Document Type: Article
Times cited : (37)

References (51)
  • 1
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen P, Kesari S. Malignant gliomas in adults. New Engl J Med 2008;359:492-507.
    • (2008) New Engl J Med , vol.359 , pp. 492-507
    • Wen, P.1    Kesari, S.2
  • 3
    • 77956224494 scopus 로고    scopus 로고
    • Oxygen in stem cell biology: A critical component of the stem cell niche
    • Mohyeldin A, Garzon-Muvdi T, Quinones-Hinojosa A. Oxygen in stem cell biology: A critical component of the stem cell niche. Cell Stem Cell 2010;7:150-161.
    • (2010) Cell Stem Cell , vol.7 , pp. 150-161
    • Mohyeldin, A.1    Garzon-Muvdi, T.2    Quinones-Hinojosa, A.3
  • 4
    • 77649273107 scopus 로고    scopus 로고
    • Hypoxia inducible factors in cancer stem cells
    • Heddleston JM, Li Z, Lathia JD et al. Hypoxia inducible factors in cancer stem cells. Br J Cancer 2010;102:789-795.
    • (2010) Br J Cancer , vol.102 , pp. 789-795
    • Heddleston, J.M.1    Li, Z.2    Lathia, J.D.3
  • 5
    • 79251591038 scopus 로고    scopus 로고
    • Glioblastoma, cancer stem cells and hypoxia
    • Bar EE. Glioblastoma, cancer stem cells and hypoxia. Brain Pathol 2011;21:119-129.
    • (2011) Brain Pathol , vol.21 , pp. 119-129
    • Bar, E.E.1
  • 6
    • 65649115060 scopus 로고    scopus 로고
    • Hypoxia helps glioma to fight therapy
    • Amberger-Murphy V. Hypoxia helps glioma to fight therapy. Curr Cancer Drug Targets 2009;9:381-390.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 381-390
    • Amberger-Murphy, V.1
  • 7
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007;129: 465-472.
    • (2007) Cell , vol.129 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 8
    • 65249131228 scopus 로고    scopus 로고
    • Brain tumor hypoxia: Tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target
    • Jensen R. Brain tumor hypoxia: Tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target. J Neurooncol 2009;92:317-335.
    • (2009) J Neurooncol , vol.92 , pp. 317-335
    • Jensen, R.1
  • 9
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S, Wu Q et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009;15:501-513.
    • (2009) Cancer Cell , vol.15 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3
  • 10
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-737.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 11
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • Galli R, Binda E, Orfanelli U et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 2004;64:7011-7021.
    • (2004) Cancer Res , vol.64 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3
  • 12
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID et al. Identification of human brain tumour initiating cells. Nature 2004;432:396-401.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 13
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF et al. Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-111.
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3
  • 14
    • 69249139924 scopus 로고    scopus 로고
    • Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens
    • Kelly JJ, Stechishin O, Chojnacki A et al. Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens. STEM CELLS 2009;27:1722-1733.
    • (2009) Stem Cells , vol.27 , pp. 1722-1733
    • Kelly, J.J.1    Stechishin, O.2    Chojnacki, A.3
  • 15
    • 63849225752 scopus 로고    scopus 로고
    • Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
    • Wakimoto H, Kesari S, Farrell CJ et al. Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res 2009;69:3472-3481.
    • (2009) Cancer Res , vol.69 , pp. 3472-3481
    • Wakimoto, H.1    Kesari, S.2    Farrell, C.J.3
  • 16
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston JM, Li Z, McLendon RE et al. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009;8:3274-3284.
    • (2009) Cell Cycle , vol.8 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3
  • 17
    • 64149101418 scopus 로고    scopus 로고
    • Tumor initiating cells in malignant gliomas: Biology and implications for therapy
    • Hadjipanayis CG. Tumor initiating cells in malignant gliomas: Biology and implications for therapy. J Mol Med 2009;87:363-374.
    • (2009) J Mol Med , vol.87 , pp. 363-374
    • Hadjipanayis, C.G.1
  • 18
    • 68549104117 scopus 로고    scopus 로고
    • The role of oxygen in regulating neural stem cells in development and disease
    • Panchision DM. The role of oxygen in regulating neural stem cells in development and disease. J Cell Physiol 2009;220:562-568.
    • (2009) J Cell Physiol , vol.220 , pp. 562-568
    • Panchision, D.M.1
  • 19
    • 77956503727 scopus 로고    scopus 로고
    • Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres
    • Bar EE, Lin A, Mahairaki V et al. Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol 2010;177:1491-1502.
    • (2010) Am J Pathol , vol.177 , pp. 1491-1502
    • Bar, E.E.1    Lin, A.2    Mahairaki, V.3
  • 20
    • 16344380951 scopus 로고    scopus 로고
    • 2 tensions and the prevention of differentiation of hES cells
    • 2 tensions and the prevention of differentiation of hES cells. Proc Natl Acad Sci USA 2005;102: 4783-4788.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4783-4788
    • Ezashi, T.1    Das, P.2    Roberts, R.M.3
  • 21
    • 77950838848 scopus 로고    scopus 로고
    • A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2
    • Seidel S, Garvalov BK, Wirta V et al. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2. Brain 2010;133:983-995.
    • (2010) Brain , vol.133 , pp. 983-995
    • Seidel, S.1    Garvalov, B.K.2    Wirta, V.3
  • 22
    • 70449687092 scopus 로고    scopus 로고
    • Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α
    • Soeda A, Park M, Lee D et al. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α. Oncogene 2009;28:3949-3959.
    • (2009) Oncogene , vol.28 , pp. 3949-3959
    • Soeda, A.1    Park, M.2    Lee, D.3
  • 23
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006;444:756-760.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 24
    • 78751649494 scopus 로고    scopus 로고
    • Cancer stem cells: The final frontier for glioma virotherapy
    • Dey M, Ulasov IV, Tyler MA et al. Cancer stem cells: The final frontier for glioma virotherapy. Stem Cell Rev 2011;7:119-129.
    • (2011) Stem Cell Rev , vol.7 , pp. 119-129
    • Dey, M.1    Ulasov, I.V.2    Tyler, M.A.3
  • 25
    • 44649137314 scopus 로고    scopus 로고
    • CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors
    • Beier D, Wischhusen J, Dietmaier W et al. CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors. Brain Pathol 2008;18:370-377.
    • (2008) Brain Pathol , vol.18 , pp. 370-377
    • Beier, D.1    Wischhusen, J.2    Dietmaier, W.3
  • 26
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD133 cancer stem cells in glioblastoma
    • Liu G, Yuan X, Zeng Z et al. Analysis of gene expression and chemoresistance of CD133 cancer stem cells in glioblastoma. Mol Cancer 2006;5:67.
    • (2006) Mol Cancer , vol.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3
  • 27
    • 40749155451 scopus 로고    scopus 로고
    • Stem cell marker CD133 affects clinical outcome in glioma patients
    • Zeppernick F, Ahmadi R, Campos B et al. Stem cell marker CD133 affects clinical outcome in glioma patients. Clin Cancer Res 2008; 14:123-129.
    • (2008) Clin Cancer Res , vol.14 , pp. 123-129
    • Zeppernick, F.1    Ahmadi, R.2    Campos, B.3
  • 28
    • 34249332411 scopus 로고    scopus 로고
    • CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
    • Beier D, Hau P, Proescholdt M et al. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 2007;67:4010-4015.
    • (2007) Cancer Res , vol.67 , pp. 4010-4015
    • Beier, D.1    Hau, P.2    Proescholdt, M.3
  • 29
    • 77950502115 scopus 로고    scopus 로고
    • A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
    • Chen R, Nishimura MC, Bumbaca SM et al. A hierarchy of self-renewing tumor-initiating cell types in glioblastoma. Cancer Cell 2010; 17:362-375.
    • (2010) Cancer Cell , vol.17 , pp. 362-375
    • Chen, R.1    Nishimura, M.C.2    Bumbaca, S.M.3
  • 30
    • 12944315014 scopus 로고    scopus 로고
    • Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase I trial
    • Markert JM, Medlock MD, Rabkin SD et al. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase I trial. Gene Ther 2000;7:867-874.
    • (2000) Gene Ther , vol.7 , pp. 867-874
    • Markert, J.M.1    Medlock, M.D.2    Rabkin, S.D.3
  • 31
    • 27944433469 scopus 로고    scopus 로고
    • Oncolytic viral therapies: The clinical experience
    • Aghi M, Martuza RL. Oncolytic viral therapies: The clinical experience. Oncogene 2005; 24:7802-7816.
    • (2005) Oncogene , vol.24 , pp. 7802-7816
    • Aghi, M.1    Martuza, R.L.2
  • 32
    • 58149237728 scopus 로고    scopus 로고
    • Phase Ib trial of mutant herpes simplex virus G207 inoculated preand post-tumor resection for recurrent GBM
    • Markert JM, Liechty PG, Wang W et al. Phase Ib trial of mutant herpes simplex virus G207 inoculated preand post-tumor resection for recurrent GBM. Mol Ther 2009;17: 199-207.
    • (2009) Mol Ther , vol.17 , pp. 199-207
    • Markert, J.M.1    Liechty, P.G.2    Wang, W.3
  • 33
    • 58149214278 scopus 로고    scopus 로고
    • Hypoxia enhances the replication of oncolytic herpes simplex virus
    • Aghi MK, Liu TC, Rabkin S, et al. Hypoxia enhances the replication of oncolytic herpes simplex virus. Mol Ther 2009;17:51-56.
    • (2009) Mol Ther , vol.17 , pp. 51-56
    • Aghi, M.K.1    Liu, T.C.2    Rabkin, S.3
  • 34
    • 0035933088 scopus 로고    scopus 로고
    • Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
    • Todo T, Martuza RL, Rabkin SD et al. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc Natl Acad Sci USA 2001;98: 6396-6401.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6396-6401
    • Todo, T.1    Martuza, R.L.2    Rabkin, S.D.3
  • 35
    • 28244502278 scopus 로고    scopus 로고
    • Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system
    • Fukuhara H, Ino Y, Kuroda T et al. Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Res 2005;65:10663-10668.
    • (2005) Cancer Res , vol.65 , pp. 10663-10668
    • Fukuhara, H.1    Ino, Y.2    Kuroda, T.3
  • 36
    • 0025876227 scopus 로고
    • Regulation of herpes simplex virus true late gene expression: Sequences downstream from the US11 TATA box inhibit expression from an unreplicated template
    • Kibler PK, Duncan J, Keith BD et al. Regulation of herpes simplex virus true late gene expression: Sequences downstream from the US11 TATA box inhibit expression from an unreplicated template. J Virol 1991;65:6749-6760.
    • (1991) J Virol , vol.65 , pp. 6749-6760
    • Kibler, P.K.1    Duncan, J.2    Keith, B.D.3
  • 37
    • 0028149276 scopus 로고
    • Transcriptional activation of the herpes simplex virus type 1 UL38 promoter conferred by the cisacting downstream activation sequence is mediated by a cellular transcription factor
    • Guzowski JF, Singh J, Wagner EK. Transcriptional activation of the herpes simplex virus type 1 UL38 promoter conferred by the cisacting downstream activation sequence is mediated by a cellular transcription factor. J Virol 1994;68:7774-7789.
    • (1994) J Virol , vol.68 , pp. 7774-7789
    • Guzowski, J.F.1    Singh, J.2    Wagner, E.K.3
  • 38
    • 33750074397 scopus 로고    scopus 로고
    • FlipFlop HSV-BAC: Bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases
    • Kuroda T, Martuza RL, Todo T et al. FlipFlop HSV-BAC: Bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases. BMC Biotechnol 2006;6:40.
    • (2006) BMC Biotechnol , vol.6 , pp. 40
    • Kuroda, T.1    Martuza, R.L.2    Todo, T.3
  • 39
    • 79957881687 scopus 로고    scopus 로고
    • A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells
    • Kanai R, Wakimoto H, Martuza RL et al. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clin Cancer Res 2011;17:3686-3696.
    • (2011) Clin Cancer Res , vol.17 , pp. 3686-3696
    • Kanai, R.1    Wakimoto, H.2    Martuza, R.L.3
  • 40
    • 65749087298 scopus 로고    scopus 로고
    • Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
    • Laks DR, Masterman-Smith M, Visnyei K et al. Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. STEM CELLS 2009;27:980-987.
    • (2009) Stem Cells , vol.27 , pp. 980-987
    • Laks, D.R.1    Masterman-Smith, M.2    Visnyei, K.3
  • 41
    • 56349113871 scopus 로고    scopus 로고
    • CD133 is a marker of bioenergetic stress in human glioma
    • Griguer CE, Oliva CR, Gobin E et al. CD133 is a marker of bioenergetic stress in human glioma. PLoS One 2008;3:e3655.
    • (2008) PLoS One , vol.3
    • Griguer, C.E.1    Oliva, C.R.2    Gobin, E.3
  • 42
    • 78650705036 scopus 로고    scopus 로고
    • Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis
    • Pallini R, Ricci-Vitiani L, Montano N et al. Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis. Cancer 2011;117:162-174.
    • (2011) Cancer , vol.117 , pp. 162-174
    • Pallini, R.1    Ricci-Vitiani, L.2    Montano, N.3
  • 43
    • 69949134899 scopus 로고    scopus 로고
    • Glioblastoma formation from cell population depleted of Prominin1-expressing cells
    • Nishide K, Nakatani Y, Kiyonari H et al. Glioblastoma formation from cell population depleted of Prominin1-expressing cells. PLoS One 2009;4:e6869.
    • (2009) PLoS One , vol.4
    • Nishide, K.1    Nakatani, Y.2    Kiyonari, H.3
  • 44
    • 78649900502 scopus 로고    scopus 로고
    • Insight into the complex regulation of CD133 in glioma
    • Campos B, Herold-Mende CC. Insight into the complex regulation of CD133 in glioma. Int J Cancer 2011;128:501-510.
    • (2011) Int J Cancer , vol.128 , pp. 501-510
    • Campos, B.1    Herold-Mende, C.C.2
  • 46
    • 33947428335 scopus 로고    scopus 로고
    • Maintenance of endoplasmic reticulum (ER) homeostasis in herpes simplex virus type 1-infected cells through the association of a viral glycoprotein with PERK, a cellular ER stress sensor
    • Mulvey M, Arias C, Mohr I. Maintenance of endoplasmic reticulum (ER) homeostasis in herpes simplex virus type 1-infected cells through the association of a viral glycoprotein with PERK, a cellular ER stress sensor. J Virol 2007;81:3377-3390.
    • (2007) J Virol , vol.81 , pp. 3377-3390
    • Mulvey, M.1    Arias, C.2    Mohr, I.3
  • 47
    • 0036837864 scopus 로고    scopus 로고
    • Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
    • Koumenis C, Naczki C, Koritzinsky M et al. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α. Mol Cell Biol 2002;22: 7405-7416.
    • (2002) Mol Cell Biol , vol.22 , pp. 7405-7416
    • Koumenis, C.1    Naczki, C.2    Koritzinsky, M.3
  • 48
    • 73949120145 scopus 로고    scopus 로고
    • 1 arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2α phosphorylation
    • 1 arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2α phosphorylation. Neoplasia 2010;12:61-68.
    • (2010) Neoplasia , vol.12 , pp. 61-68
    • Liu, Y.1    Laszlo, C.2    Liu, Y.3
  • 49
    • 68049110425 scopus 로고    scopus 로고
    • Hypoxia enhances the replication of oncolytic herpes simplex virus in p53 breast cancer cells
    • Fasullo M, Burch AD, Britton A. Hypoxia enhances the replication of oncolytic herpes simplex virus in p53 breast cancer cells. Cell Cycle 2009;8:2194-2197.
    • (2009) Cell Cycle , vol.8 , pp. 2194-2197
    • Fasullo, M.1    Burch, A.D.2    Britton, A.3
  • 50
    • 42649106141 scopus 로고    scopus 로고
    • Hypoxia induces protection against etoposideinduced apoptosis: Molecular profiling of changes in gene expression and transcription factor activity
    • Sermeus A, Cosse JP, Crespin M et al. Hypoxia induces protection against etoposideinduced apoptosis: Molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer 2008;7:27.
    • (2008) Mol Cancer , vol.7 , pp. 27
    • Sermeus, A.1    Cosse, J.P.2    Crespin, M.3


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