메뉴 건너뛰기




Volumn 6, Issue , 2006, Pages

Flip-flop HSV-BAC: Bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ARTIFICIAL CHROMOSOME; HERPES SIMPLEX VIRUS (HSV); RECOMBINANT VIRUS; TUMOR CELLS;

EID: 33750074397     PISSN: 14726750     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-6-40     Document Type: Article
Times cited : (38)

References (50)
  • 1
    • 27944433469 scopus 로고    scopus 로고
    • Oncolytic viral therapies - The clinical experience
    • Aghi M, Martuza RL: Oncolytic viral therapies - the clinical experience. Oncogene 2005, 24:7802-7816.
    • (2005) Oncogene , vol.24 , pp. 7802-7816
    • Aghi, M.1    Martuza, R.L.2
  • 2
    • 0025864440 scopus 로고
    • Experimental therapy of human giloma by means of a genetically engineered virus mutant
    • Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM: Experimental therapy of human giloma by means of a genetically engineered virus mutant. Science 1991, 252:854-856.
    • (1991) Science , vol.252 , pp. 854-856
    • Martuza, R.L.1    Malick, A.2    Markert, J.M.3    Ruffner, K.L.4    Coen, D.M.5
  • 4
    • 0030957912 scopus 로고    scopus 로고
    • Transcriptional targeting of herpes simplex virus for cell-specific replication
    • Miyatake S, Iyer A, Martuza RL, Rabkin SD: Transcriptional targeting of herpes simplex virus for cell-specific replication. J Virol 1997, 71:5124-5132.
    • (1997) J Virol , vol.71 , pp. 5124-5132
    • Miyatake, S.1    Iyer, A.2    Martuza, R.L.3    Rabkin, S.D.4
  • 5
    • 0031870243 scopus 로고    scopus 로고
    • An enhanced packaging system for helper-dependent herpes simplex virus vectors
    • Stavropoulos TA, Strathdee CA: An enhanced packaging system for helper-dependent herpes simplex virus vectors. J Virol 1998, 72:7137-7143.
    • (1998) J Virol , vol.72 , pp. 7137-7143
    • Stavropoulos, T.A.1    Strathdee, C.A.2
  • 6
    • 0033055019 scopus 로고    scopus 로고
    • Allele replacement: An application that permits rapid manipulation of herpes simplex virus type I genomes
    • Horsburgh BC, Hubinette MM, Qiang D, MacDonald ML, Tufaro F. Allele replacement: an application that permits rapid manipulation of herpes simplex virus type I genomes. Gene Ther 1999, 6:922-930.
    • (1999) Gene Ther , vol.6 , pp. 922-930
    • Horsburgh, B.C.1    Hubinette, M.M.2    Qiang, D.3    MacDonald, M.L.4    Tufaro, F.5
  • 7
    • 0032506707 scopus 로고    scopus 로고
    • Herpes simplex virus type I DNA amplified as bacterial artificial chromosome in Escherichia coli: Rescue of replication-competent virus progeny and packaging of amplicon vectors
    • Saeli Y, Ichikawa T, Saeki A, Chiocca EA, Tobler K, Ackermann M, Breakefield XO, Fraefel C: Herpes simplex virus type I DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors. Hum Gene Ther 1998, 9:2787-2794.
    • (1998) Hum Gene Ther , vol.9 , pp. 2787-2794
    • Saeli, Y.1    Ichikawa, T.2    Saeki, A.3    Chiocca, E.A.4    Tobler, K.5    Ackermann, M.6    Breakefield, X.O.7    Fraefel, C.8
  • 8
    • 0037228038 scopus 로고    scopus 로고
    • Construction of an excisable bacterial artificial chromosome containing a full-length infectious clone of herpes simplex virus type I: Viruses reconstituted from the clone exhibit wild-type properties in vitro and in vivo
    • Tanaka M, Kagawa H, Yamanashi Y, Sata T, Kawaguchi Y: Construction of an excisable bacterial artificial chromosome containing a full-length infectious clone of herpes simplex virus type I: viruses reconstituted from the clone exhibit wild-type properties in vitro and in vivo. J Virol 2003, 77:1382-1391.
    • (2003) J Virol , vol.77 , pp. 1382-1391
    • Tanaka, M.1    Kagawa, H.2    Yamanashi, Y.3    Sata, T.4    Kawaguchi, Y.5
  • 9
    • 0033912858 scopus 로고    scopus 로고
    • Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome
    • Adler H, Messerle M, Wagner M, Koszinowski UH: Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J Virol 2000, 74:6964-6974.
    • (2000) J Virol , vol.74 , pp. 6964-6974
    • Adler, H.1    Messerle, M.2    Wagner, M.3    Koszinowski, U.H.4
  • 10
    • 0036720530 scopus 로고    scopus 로고
    • The human cytomegalovirus ribonucleotide reductase homolog UL45 is dispensable for growth in endothelial cells, as determined by a BAC-cloned clinical isolate of human cytomegalovirus with preserved wild-type characteristics
    • Hahn G, Khan H, Baldanti F, Koszinowski UH, Revello MG, Gerna G: The human cytomegalovirus ribonucleotide reductase homolog UL45 is dispensable for growth in endothelial cells, as determined by a BAC-cloned clinical isolate of human cytomegalovirus with preserved wild-type characteristics. J Virol 2002, 76:9551-9555.
    • (2002) J Virol , vol.76 , pp. 9551-9555
    • Hahn, G.1    Khan, H.2    Baldanti, F.3    Koszinowski, U.H.4    Revello, M.G.5    Gerna, G.6
  • 11
    • 0032798391 scopus 로고    scopus 로고
    • Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus
    • Smith GA, Enquist LW: Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus. J Virol 1999, 73:6405-6414.
    • (1999) J Virol , vol.73 , pp. 6405-6414
    • Smith, G.A.1    Enquist, L.W.2
  • 12
    • 0032925098 scopus 로고    scopus 로고
    • Transposing BACs to the future
    • Strathdee CA: Transposing BACs to the future. Nat Biotechnol 1999, 17:332-333.
    • (1999) Nat Biotechnol , vol.17 , pp. 332-333
    • Strathdee, C.A.1
  • 13
    • 0034467231 scopus 로고    scopus 로고
    • Reconstitution of Marek's disease virus serotype 1 (MDV-1) from DNA cloned as a bacterial artificial chromosome and characterization of a glycoprotein B-negative B-negative MDV-I mutant
    • Schumacher D, Tischer BK, Fuchs W, Osterrieder N: Reconstitution of Marek's disease virus serotype 1 (MDV-1) from DNA cloned as a bacterial artificial chromosome and characterization of a glycoprotein B-negative B-negative MDV-I mutant. J Virol 2000, 74:11088-11098.
    • (2000) J Virol , vol.74 , pp. 11088-11098
    • Schumacher, D.1    Tischer, B.K.2    Fuchs, W.3    Osterrieder, N.4
  • 15
    • 18744391980 scopus 로고    scopus 로고
    • Engineering of a vaccinia virus bacterial artificial chromosome in Escherichia coli by bacteriophage lambda-based recombination
    • Domi A, Moss B: Engineering of a vaccinia virus bacterial artificial chromosome in Escherichia coli by bacteriophage lambda-based recombination. Nat Methods 2005, 2:95-97.
    • (2005) Nat Methods , vol.2 , pp. 95-97
    • Domi, A.1    Moss, B.2
  • 16
    • 0347382541 scopus 로고    scopus 로고
    • Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence
    • White RE, Calderwood MA, Whitehouse A: Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence. J Gen Virol 2003, 84:3393-3403.
    • (2003) J Gen Virol , vol.84 , pp. 3393-3403
    • White, R.E.1    Calderwood, M.A.2    Whitehouse, A.3
  • 17
    • 0038237520 scopus 로고    scopus 로고
    • Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells
    • Wade-Martins R, Saeki Y, Chiocca EA: Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells. Mol Ther 2003, 7:604-612.
    • (2003) Mol Ther , vol.7 , pp. 604-612
    • Wade-Martins, R.1    Saeki, Y.2    Chiocca, E.A.3
  • 18
    • 0034756520 scopus 로고    scopus 로고
    • An infectious transfer and expression system for genomic DNA loci in human and mouse cells
    • Wade-Martins R, Smith ER, Tyminski E, Chiocca EA, Saeki Y: An infectious transfer and expression system for genomic DNA loci in human and mouse cells. Nat Biotechnol 2001, 19:1067-1070.
    • (2001) Nat Biotechnol , vol.19 , pp. 1067-1070
    • Wade-Martins, R.1    Smith, E.R.2    Tyminski, E.3    Chiocca, E.A.4    Saeki, Y.5
  • 19
    • 0026703169 scopus 로고
    • Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coil using an F-factor-based vector
    • Shizuya H, Birren B, Kim UJ, Mancino V, Slepak T, Tachiiri Y, Simon M: Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coil using an F-factor-based vector. Proc Natl Acad Sci U S A 1992, 89:8794-8797.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 8794-8797
    • Shizuya, H.1    Birren, B.2    Kim, U.J.3    Mancino, V.4    Slepak, T.5    Tachiiri, Y.6    Simon, M.7
  • 20
    • 0034997340 scopus 로고    scopus 로고
    • Virus reconstituted from infectious bacterial artificial chromosome (BAC)-cloned murine gammaherpesvirus 68 acquires wild-type properties in vivo only after excision of BAC vector sequences
    • Adler H, Messerle M, Koszinowski UH: Virus reconstituted from infectious bacterial artificial chromosome (BAC)-cloned murine gammaherpesvirus 68 acquires wild-type properties in vivo only after excision of BAC vector sequences. J Virol 2001, 75:5692-5696.
    • (2001) J Virol , vol.75 , pp. 5692-5696
    • Adler, H.1    Messerle, M.2    Koszinowski, U.H.3
  • 21
    • 0034712723 scopus 로고    scopus 로고
    • A self-recombining bacterial artificial chromosome and its application for analysis of herpesvirus pathogenesis
    • Smith GA, Enquist LW: A self-recombining bacterial artificial chromosome and its application for analysis of herpesvirus pathogenesis. Proc Natl Acad Sci U S A 2000, 97:4873-4878.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4873-4878
    • Smith, G.A.1    Enquist, L.W.2
  • 22
    • 0022358365 scopus 로고
    • Isolation a characterization of deletion mutants of herpes simplex virus type I in the gene encoding immediate-early regulatory protein ICP4
    • DeLuca NA, McCarthy AM, Schaffer PA: Isolation a characterization of deletion mutants of herpes simplex virus type I in the gene encoding immediate-early regulatory protein ICP4. J Virol 1985, 56:558-570.
    • (1985) J Virol , vol.56 , pp. 558-570
    • DeLuca, N.A.1    McCarthy, A.M.2    Schaffer, P.A.3
  • 23
    • 0035958292 scopus 로고    scopus 로고
    • Regulation of herpes simplex virus gene expression
    • Weir JP: Regulation of herpes simplex virus gene expression. Gene 2001, 271:117-130.
    • (2001) Gene , vol.271 , pp. 117-130
    • Weir, J.P.1
  • 25
    • 0035872445 scopus 로고    scopus 로고
    • Identification of the transcriptional regulatory sequences of human calponin promoter and their use in targeting a conditionally replicating herpes vector to malignant human soft tissue and bone tumors
    • Yamamura H, Hashio M, Noguchi M, Sugenoya Y, Osakada M, Hirano N, Sasaki Y, Yoden T, Awata N, Araki N, Tatsuta M, Miyatake SI, Takahashi K: Identification of the transcriptional regulatory sequences of human calponin promoter and their use in targeting a conditionally replicating herpes vector to malignant human soft tissue and bone tumors. Cancer Res 2001, 61:3969-3977.
    • (2001) Cancer Res , vol.61 , pp. 3969-3977
    • Yamamura, H.1    Hashio, M.2    Noguchi, M.3    Sugenoya, Y.4    Osakada, M.5    Hirano, N.6    Sasaki, Y.7    Yoden, T.8    Awata, N.9    Araki, N.10    Tatsuta, M.11    Miyatake, S.I.12    Takahashi, K.13
  • 26
    • 0023695728 scopus 로고
    • Factor(s) present in herpes simplex virus type I-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: Characterization of an ICP6 deletion mutant
    • Goldstein DJ, Weller SK: Factor(s) present in herpes simplex virus type I-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant. Virology 1988, 166:41-51.
    • (1988) Virology , vol.166 , pp. 41-51
    • Goldstein, D.J.1    Weller, S.K.2
  • 27
    • 0029023868 scopus 로고
    • Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
    • Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL: Attenuated. multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med 1995, 1:938-943.
    • (1995) Nat Med , vol.1 , pp. 938-943
    • Mineta, T.1    Rabkin, S.D.2    Yazaki, T.3    Hunter, W.D.4    Martuza, R.L.5
  • 28
    • 0033950232 scopus 로고    scopus 로고
    • An oncolytic herpes simplex virus type I selectively destroys diffuse liver metastases, from colon carcinoma
    • Yoon SS, Nakamura H, Carroll NM, Bode BP, Chiocca EA, Tanabe KK: An oncolytic herpes simplex virus type I selectively destroys diffuse liver metastases, from colon carcinoma. Faseb J 2000, 14:301-311.
    • (2000) Faseb J , vol.14 , pp. 301-311
    • Yoon, S.S.1    Nakamura, H.2    Carroll, N.M.3    Bode, B.P.4    Chiocca, E.A.5    Tanabe, K.K.6
  • 29
    • 0035925583 scopus 로고    scopus 로고
    • Simple and efficient vectors for retrofitting BACs and PACs with mammalian neoR and EGFP marker genes
    • Kaname T, Huxley C: Simple and efficient vectors for retrofitting BACs and PACs with mammalian neoR and EGFP marker genes. Gene 2001, 266:147-153.
    • (2001) Gene , vol.266 , pp. 147-153
    • Kaname, T.1    Huxley, C.2
  • 31
    • 27944471015 scopus 로고    scopus 로고
    • Development of transcriptionally regulated oncolytic adenoviruses
    • Ko D, Hawkins L, Yu DC: Development of transcriptionally regulated oncolytic adenoviruses Oncogene 2005 24:7763-7774.
    • (2005) Oncogene , vol.24 , pp. 7763-7774
    • Ko, D.1    Hawkins, L.2    Yu, D.C.3
  • 32
    • 16844366956 scopus 로고    scopus 로고
    • An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor
    • Kambara H, Okano H, Chiocca EA Saeki Y: An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. Cancer Res 2005, 65:2832-2839.
    • (2005) Cancer Res , vol.65 , pp. 2832-2839
    • Kambara, H.1    Okano, H.2    Chiocca, E.A.3    Saeki, Y.4
  • 33
    • 28244502278 scopus 로고    scopus 로고
    • Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleuldn 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system
    • Fukuhara H, Ino Y, Kuroda T, Martuza RL, Todo T: Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleuldn 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Res 2005, 65:10663-10668.
    • (2005) Cancer Res , vol.65 , pp. 10663-10668
    • Fukuhara, H.1    Ino, Y.2    Kuroda, T.3    Martuza, R.L.4    Todo, T.5
  • 34
    • 31544468273 scopus 로고    scopus 로고
    • Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models
    • Terada K, Wakimoto H, Tyminski E, Chiocca EA, Saeki Y: Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models. Gene Ther 2006, 13:705-714.
    • (2006) Gene Ther , vol.13 , pp. 705-714
    • Terada, K.1    Wakimoto, H.2    Tyminski, E.3    Chiocca, E.A.4    Saeki, Y.5
  • 35
    • 0034991897 scopus 로고    scopus 로고
    • Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome
    • Saeki Y, Fraefel C, Ichikawa T, Breakefield XO, Chiocca EA: Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. Mol Ther 2001, 3:591-601.
    • (2001) Mol Ther , vol.3 , pp. 591-601
    • Saeki, Y.1    Fraefel, C.2    Ichikawa, T.3    Breakefield, X.O.4    Chiocca, E.A.5
  • 36
    • 0031821936 scopus 로고    scopus 로고
    • Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients
    • Gaudreau A, Hill E, Balfour HHJ, Erice A, Boivin G: Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients. J Infect Dis 1998, 178:297-303.
    • (1998) J Infect Dis , vol.178 , pp. 297-303
    • Gaudreau, A.1    Hill, E.2    Balfour, H.H.J.3    Erice, A.4    Boivin, G.5
  • 37
    • 0028108669 scopus 로고
    • Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant
    • Mineta T, Rabkin SD, Martuza RL: Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Res 1994, 54:3963-3966.
    • (1994) Cancer Res , vol.54 , pp. 3963-3966
    • Mineta, T.1    Rabkin, S.D.2    Martuza, R.L.3
  • 38
    • 0024385506 scopus 로고
    • Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir
    • Coen DM, Goldstein DJ, Weller SK: Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir. Andmicrob Agents Chemother 1989, 33:1395-1399.
    • (1989) Andmicrob Agents Chemother , vol.33 , pp. 1395-1399
    • Coen, D.M.1    Goldstein, D.J.2    Weller, S.K.3
  • 39
    • 0022397547 scopus 로고
    • Activation of the major Immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific transacting components
    • Stinski MF, Roehr TJ: Activation of the major Immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific transacting components. J Virol 1985, 55:431-44
    • (1985) J Virol , vol.55 , pp. 431-444
    • Stinski, M.F.1    Roehr, T.J.2
  • 40
    • 0031947861 scopus 로고    scopus 로고
    • Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins
    • Samaniego LA, Neiderhiser L, DeLuca NA: Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J Virol 1998, 72:3307-3320.
    • (1998) J Virol , vol.72 , pp. 3307-3320
    • Samaniego, L.A.1    Neiderhiser, L.2    DeLuca, N.A.3
  • 41
    • 0030801241 scopus 로고    scopus 로고
    • Repression of gene expression upon infection of cells with herpes simplex virus type I mutants impaired for imniediate-early protein synthesis
    • Preston CM, Nicholl MJ: Repression of gene expression upon infection of cells with herpes simplex virus type I mutants impaired for imniediate-early protein synthesis. J Virol 1997, 71:7807-7813.
    • (1997) J Virol , vol.71 , pp. 7807-7813
    • Preston, C.M.1    Nicholl, M.J.2
  • 42
    • 84872267462 scopus 로고    scopus 로고
    • Effective treatment of tumors with strong beta-catenin/Tcf activity by transcriptionally targeted oncolytic herpes simplex virus vector
    • in press
    • Kuroda T, Rabkin SD, Martuza RL: Effective treatment of tumors with strong beta-catenin/Tcf activity by transcriptionally targeted oncolytic herpes simplex virus vector. Cancer Res in press.
    • Cancer Res
    • Kuroda, T.1    Rabkin, S.D.2    Martuza, R.L.3
  • 43
    • 0030860068 scopus 로고    scopus 로고
    • Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors
    • Addison CL, Hitt M, Kunsken D, Graham FL: Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. J Gen Virol 1997, 78 (Pt 7):1653-1661.
    • (1997) J Gen Virol , vol.78 , Issue.PART 7 , pp. 1653-1661
    • Addison, C.L.1    Hitt, M.2    Kunsken, D.3    Graham, F.L.4
  • 45
    • 0022977978 scopus 로고
    • Powerful and versatile enhancerpromoter unit for mammalian expression vectors
    • Foecking MK, Hofstetter H: Powerful and versatile enhancerpromoter unit for mammalian expression vectors. Gene 1986,45:101-105.
    • (1986) Gene , vol.45 , pp. 101-105
    • Foecking, M.K.1    Hofstetter, H.2
  • 46
    • 0026008881 scopus 로고
    • The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice
    • Furth PA, Hennighausen L, Baker C, Beatty B, Woychick R: The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice. Nucleic Acids Res 1991, 19:6205-6208.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6205-6208
    • Furth, P.A.1    Hennighausen, L.2    Baker, C.3    Beatty, B.4    Woychick, R.5
  • 47
    • 0023880185 scopus 로고
    • Herpes simplex virus type I-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: Isolation and characterization of an ICP6 lacZ insertion mutant
    • Goldstein DJ, Weller SK: Herpes simplex virus type I-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant. J Virol 1988,62:196-205.
    • (1988) J Virol , vol.62 , pp. 196-205
    • Goldstein, D.J.1    Weller, S.K.2
  • 48
    • 0035005627 scopus 로고    scopus 로고
    • Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination
    • Umana P, Gerdes CA, Stone D, Davis JR, Ward D, Castro MG, Lowenstein PR: Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination. Nat Biotechnol 2001, 19:582-585.
    • (2001) Nat Biotechnol , vol.19 , pp. 582-585
    • Umana, P.1    Gerdes, C.A.2    Stone, D.3    Davis, J.R.4    Ward, D.5    Castro, M.G.6    Lowenstein, P.R.7
  • 49
    • 0017144759 scopus 로고
    • A new method for the isolation of herpes simplex virus type 2 DNA
    • Walboomers JM, Schegget JT: A new method for the isolation of herpes simplex virus type 2 DNA. Virology 1976, 74:256-258.
    • (1976) Virology , vol.74 , pp. 256-258
    • Walboomers, J.M.1    Schegget, J.T.2
  • 50
    • 0027934404 scopus 로고
    • Rapid small-scale isolation of herpes simplex virus DNA
    • Kintner RL, Brandt CR: Rapid small-scale isolation of herpes simplex virus DNA. J Virol Methods 1994, 48:189-196.
    • (1994) J Virol Methods , vol.48 , pp. 189-196
    • Kintner, R.L.1    Brandt, C.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.