-
1
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel, R., Naishadham, D. & Jemal, A. Cancer statistics, 2012. CA Cancer J. Clin. 62, 10-29 (2012).
-
(2012)
CA Cancer J. Clin.
, vol.62
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
84928580276
-
Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
-
Huggins, C. & Hodges, C. V. Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1, 293-297 (1941).
-
(1941)
Cancer Res.
, vol.1
, pp. 293-297
-
-
Huggins, C.1
Hodges, C.V.2
-
3
-
-
0001189211
-
Studies on prostate cancer II: The effects of castration on advanced carcinoma of the prostate gland
-
Huggins, C., Stevens, R. E. & Hodges, C. V. Studies on prostate cancer II: the effects of castration on advanced carcinoma of the prostate gland. Arch. Surg. 43, 209-223 (1941).
-
(1941)
Arch. Surg.
, vol.43
, pp. 209-223
-
-
Huggins, C.1
Stevens, R.E.2
Hodges, C.V.3
-
4
-
-
78249234992
-
Effective testosterone suppression for prostate cancer: Is there a best castration therapy? Rev
-
Gomella, L. G. Effective testosterone suppression for prostate cancer: is there a best castration therapy? Rev. Urol. 11, 52-60 (2009).
-
(2009)
Urol.
, vol.11
, pp. 52-60
-
-
Gomella, L.G.1
-
5
-
-
0036112592
-
The current state of hormonal therapy for prostate cancer
-
Hellerstedt, B. A. & Pienta, K. J. The current state of hormonal therapy for prostate cancer. CA Cancer J. Clin. 52, 154-179 (2002).
-
(2002)
CA Cancer J. Clin.
, vol.52
, pp. 154-179
-
-
Hellerstedt, B.A.1
Pienta, K.J.2
-
6
-
-
0019841416
-
Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma
-
Isaacs, J. T. & Coffey, D. S. Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma. Cancer Res. 41, 5070-5075 (1981).
-
(1981)
Cancer Res.
, vol.41
, pp. 5070-5075
-
-
Isaacs, J.T.1
Coffey, D.S.2
-
7
-
-
84858424089
-
Converting cancer therapies into cures: Lessons from infectious diseases
-
Glickman, M. S. & Sawyers, C. L. Converting cancer therapies into cures: lessons from infectious diseases. Cell 148, 1089-1098 (2012).
-
(2012)
Cell
, vol.148
, pp. 1089-1098
-
-
Glickman, M.S.1
Sawyers, C.L.2
-
8
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman, B. J. & Feldman, D. The development of androgen-independent prostate cancer. Nat. Rev. Cancer 1, 34-45 (2001).
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
9
-
-
33644675811
-
Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
-
Scher, H. I. & Sawyers, C. L. Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis. J. Clin. Oncol. 23, 8253-8261 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 8253-8261
-
-
Scher, H.I.1
Sawyers, C.L.2
-
10
-
-
77954942975
-
Duration of first off-treatment interval is prognostic for time to castration resistance and death in men with biochemical relapse of prostate cancer treated on a prospective trial of intermittent androgen deprivation
-
Yu, E. Y. et al. Duration of first off-treatment interval is prognostic for time to castration resistance and death in men with biochemical relapse of prostate cancer treated on a prospective trial of intermittent androgen deprivation. J. Clin. Oncol. 28, 2668-2673 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 2668-2673
-
-
Yu, E.Y.1
-
11
-
-
33750366075
-
Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: An early predictor of relapse or incomplete androgen suppression
-
Ryan, C. J. et al. Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression. Urology 68, 834-839 (2006).
-
(2006)
Urology
, vol.68
, pp. 834-839
-
-
Ryan, C.J.1
-
12
-
-
10844235652
-
Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program
-
Shah, R. B. et al. Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program. Cancer Res. 64, 9209-9216 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 9209-9216
-
-
Shah, R.B.1
-
13
-
-
78649888652
-
Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients
-
Crnalic, S. et al. Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients. Endocr. Relat. Cancer 17, 885-895 (2010).
-
(2010)
Endocr. Relat. Cancer
, vol.17
, pp. 885-895
-
-
Crnalic, S.1
-
14
-
-
1542574202
-
Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance
-
Holzbeierlein, J. et al. Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am. J. Pathol. 164, 217-227 (2004).
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 217-227
-
-
Holzbeierlein, J.1
-
15
-
-
0035845850
-
Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling
-
Mousses, S. et al. Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling. Oncogene 20, 6718-6723 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 6718-6723
-
-
Mousses, S.1
-
16
-
-
0036170838
-
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
-
Zegarra-Moro, O. L., Schmidt, L. J., Huang, H. & Tindall, D. J. Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Res. 62, 1008-1013 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 1008-1013
-
-
Zegarra-Moro, O.L.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
17
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen, C. D. et al. Molecular determinants of resistance to antiandrogen therapy. Nat. Med. 10, 33-39 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
-
18
-
-
33751270698
-
Short hairpin RNA knockdown of the androgen receptor attenuates ligand-independent activation and delays tumor progression
-
Cheng, H., Snoek, R., Ghaidi, F., Cox, M. E. & Rennie, P. S. Short hairpin RNA knockdown of the androgen receptor attenuates ligand-independent activation and delays tumor progression. Cancer Res. 66, 10613-10620 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 10613-10620
-
-
Cheng, H.1
Snoek, R.2
Ghaidi, F.3
Cox, M.E.4
Rennie, P.S.5
-
19
-
-
58949101975
-
Vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors
-
Snoek, R. et al. In vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors. Clin. Cancer Res. 15, 39-47 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 39-47
-
-
Snoek, R.1
-
20
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran, C. et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 324, 787-790 (2009).
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
-
21
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
-
Scher, H. I. et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet 375, 1437-1446 (2010).
-
(2010)
Lancet
, vol.375
, pp. 1437-1446
-
-
Scher, H.I.1
-
22
-
-
53749090666
-
Phase i clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
Attard, G. et al. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J. Clin. Oncol. 26, 4563-4571 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 4563-4571
-
-
Attard, G.1
-
23
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono, J. S. et al. Abiraterone and increased survival in metastatic prostate cancer. N. Engl. J. Med. 364, 1995-2005 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
-
24
-
-
37349118115
-
Androgen receptor (AR) coregulators: A diversity of functions converging on and regulating the AR transcriptional complex
-
Heemers, H. V. & Tindall, D. J. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr. Rev. 28, 778-808 (2007).
-
(2007)
Endocr. Rev.
, vol.28
, pp. 778-808
-
-
Heemers, H.V.1
Tindall, D.J.2
-
25
-
-
80053071543
-
Androgen receptor rediscovered: The new biology and targeting the androgen receptor therapeutically
-
Ryan, C. J. & Tindall, D. J. Androgen receptor rediscovered: the new biology and targeting the androgen receptor therapeutically. J. Clin. Oncol. 29, 3651-3658 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 3651-3658
-
-
Ryan, C.J.1
Tindall, D.J.2
-
26
-
-
0026319635
-
Endocrine therapy for prostate cancer
-
Labrie, F. Endocrine therapy for prostate cancer. Endocrinol. Metab. Clin. North Am. 20, 845-872 (1991).
-
(1991)
Endocrinol. Metab. Clin. North Am.
, vol.20
, pp. 845-872
-
-
Labrie, F.1
-
27
-
-
1642475101
-
The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutated androgen receptor
-
Mizokami, A. et al. The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutated androgen receptor. Cancer Res. 64, 765-771 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 765-771
-
-
Mizokami, A.1
-
28
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
-
Mostaghel, E. A. et al. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res. 67, 5033-5041 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 5033-5041
-
-
Mostaghel, E.A.1
-
29
-
-
0842311632
-
The androgen axis in recurrent prostate cancer
-
Mohler, J. L. et al. The androgen axis in recurrent prostate cancer. Clin. Cancer Res. 10, 440-448 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 440-448
-
-
Mohler, J.L.1
-
30
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough, M. et al. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res. 66, 2815-2825 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
-
31
-
-
80051963331
-
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
-
Chang, K.-H. et al. Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer. Proc. Natl Acad. Sci. USA 108, 13728-13733 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 13728-13733
-
-
Chang, K.-H.1
-
32
-
-
79951838692
-
Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer
-
Mohler, J. L. et al. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res. 71, 1486-1496 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 1486-1496
-
-
Mohler, J.L.1
-
33
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
Montgomery, R. B. et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 68, 4447-4454 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
-
34
-
-
80054021222
-
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
-
Cai, C. et al. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Res. 71, 6503-6513 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 6503-6513
-
-
Cai, C.1
-
35
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke, J. A. et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res. 68, 6407-6415 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 6407-6415
-
-
Locke, J.A.1
-
36
-
-
80052225259
-
Insulin increases de novo steroidogenesis in prostate cancer cells
-
Lubik, A. A. et al. Insulin increases de novo steroidogenesis in prostate cancer cells. Cancer Res. 71, 5754-5764 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 5754-5764
-
-
Lubik, A.A.1
-
37
-
-
0025644325
-
A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens
-
Veldscholte, J. et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem. Biophys. Res. Commun. 173, 534-540 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 534-540
-
-
Veldscholte, J.1
-
38
-
-
0034895975
-
Collocation of androgen receptor gene mutations in prostate cancer
-
Buchanan, G. et al. Collocation of androgen receptor gene mutations in prostate cancer. Clin. Cancer Res. 7, 1273-1281 (2001).
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1273-1281
-
-
Buchanan, G.1
-
39
-
-
79951530199
-
Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases
-
Fleischmann, A. et al. Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases. Prostate 71, 453-460 (2011).
-
(2011)
Prostate
, vol.71
, pp. 453-460
-
-
Fleischmann, A.1
-
40
-
-
76149107169
-
Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease
-
Donovan, M. J. et al. Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease. BJU Int. 105, 462-467 (2010).
-
(2010)
BJU Int.
, vol.105
, pp. 462-467
-
-
Donovan, M.J.1
-
41
-
-
84864017026
-
Androgen receptor (AR) aberrations in castration-resistant prostate cancer
-
Waltering, K. K., Urbanucci, A. & Visakorpi, T. Androgen receptor (AR) aberrations in castration-resistant prostate cancer. Mol. Cell Endocrinol. 360, 38-43 (2012).
-
(2012)
Mol. Cell Endocrinol.
, vol.360
, pp. 38-43
-
-
Waltering, K.K.1
Urbanucci, A.2
Visakorpi, T.3
-
42
-
-
0028944138
-
Vivo amplification of the androgen receptor gene and progression of human prostate cancer
-
Visakorpi, T. et al. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat. Genet. 9, 401-406 (1995).
-
(1995)
Nat. Genet.
, vol.9
, pp. 401-406
-
-
Visakorpi, T.1
-
43
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor, B. S. et al. Integrative genomic profiling of human prostate cancer. Cancer Cell 18, 11-22 (2010).
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
-
44
-
-
84863723010
-
The mutational landscape of lethal castration-resistant prostate cancer
-
Grasso, C. S. et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature 487, 239-243 (2012).
-
(2012)
Nature
, vol.487
, pp. 239-243
-
-
Grasso, C.S.1
-
45
-
-
84856530618
-
Common structural and epigenetic changes in the genome of castration-resistant prostate cancer
-
Friedlander, T. W. et al. Common structural and epigenetic changes in the genome of castration-resistant prostate cancer. Cancer Res. 72, 616-625 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 616-625
-
-
Friedlander, T.W.1
-
46
-
-
79961066627
-
Advancing a clinically relevant perspective of the clonal nature of cancer
-
Ruiz, C. et al. Advancing a clinically relevant perspective of the clonal nature of cancer. Proc. Natl Acad. Sci. USA 108, 12054-12059 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 12054-12059
-
-
Ruiz, C.1
-
47
-
-
0033557839
-
Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
-
Bubendorf, L. et al. Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res. 59, 803-806 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 803-806
-
-
Bubendorf, L.1
-
48
-
-
78649888666
-
The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
-
Sharma, A. et al. The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. J. Clin. Invest. 120, 4478-4492 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4478-4492
-
-
Sharma, A.1
-
49
-
-
80054761058
-
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1
-
Cai, C. et al. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell 20, 457-471 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 457-471
-
-
Cai, C.1
-
50
-
-
0037112372
-
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
-
Tepper, C. G. et al. Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res. 62, 6606-6614 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 6606-6614
-
-
Tepper, C.G.1
-
51
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm, S. M., Schmidt, L. J., Heemers, H. V., Vessella, R. L. & Tindall, D. J. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res. 68, 5469-5477 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
52
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo, Z. et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 69, 2305-2313 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
-
53
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu, R. et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res. 69, 16-22 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 16-22
-
-
Hu, R.1
-
54
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun, S. et al. Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J. Clin. Invest. 120, 2715-2730 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2715-2730
-
-
Sun, S.1
-
55
-
-
78049280194
-
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
-
Watson, P. A. et al. Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor. Proc. Natl Acad. Sci. USA 107, 16759-16765 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 16759-16765
-
-
Watson, P.A.1
-
56
-
-
84863979005
-
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
-
Hu, R. et al. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Res. 72, 3457-3462 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 3457-3462
-
-
Hu, R.1
-
57
-
-
0032532688
-
Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor
-
Hobisch, A. et al. Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor. Cancer Res. 58, 4640-4645 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 4640-4645
-
-
Hobisch, A.1
-
58
-
-
0037064106
-
Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
-
Ueda, T., Mawji, N. R., Bruchovsky, N. & Sadar, M. D. Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. J. Biol. Chem. 277, 38087-38094 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38087-38094
-
-
Ueda, T.1
Mawji, N.R.2
Bruchovsky, N.3
Sadar, M.D.4
-
59
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
Culig, Z. et al. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res. 54, 5474-5478 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 5474-5478
-
-
Culig, Z.1
-
60
-
-
0035204477
-
Neuropeptide-induced androgen independence in prostate cancer cells: Roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase
-
Lee, L. F., Guan, J., Qiu, Y. & Kung, H. J. Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol. Cell Biol. 21, 8385-8397 (2001).
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 8385-8397
-
-
Lee, L.F.1
Guan, J.2
Qiu, Y.3
Kung, H.J.4
-
61
-
-
0033022342
-
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
-
Craft, N., Shostak, Y., Carey, M. & Sawyers, C. L. A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat. Med. 5, 280-285 (1999).
-
(1999)
Nat. Med.
, vol.5
, pp. 280-285
-
-
Craft, N.1
Shostak, Y.2
Carey, M.3
Sawyers, C.L.4
-
62
-
-
33749445413
-
Regulation of androgen receptor activity by tyrosine phosphorylation
-
Guo, Z. et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell 10, 309-319 (2006).
-
(2006)
Cancer Cell
, vol.10
, pp. 309-319
-
-
Guo, Z.1
-
63
-
-
77954370361
-
Compensatory upregulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells
-
Dai, B. et al. Compensatory upregulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells. Cancer Res. 70, 5587-5596 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5587-5596
-
-
Dai, B.1
-
64
-
-
63249104202
-
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination
-
Xu, K. et al. Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell 15, 270-282 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 270-282
-
-
Xu, K.1
-
65
-
-
0142075168
-
Molecular characterization of human prostate carcinoma cell lines
-
van Bokhoven, A. et al. Molecular characterization of human prostate carcinoma cell lines. Prostate 57, 205-225 (2003).
-
(2003)
Prostate
, vol.57
, pp. 205-225
-
-
Van Bokhoven, A.1
-
66
-
-
0027093255
-
Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
-
McDonnell, T. J. et al. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res. 52, 6940-6944 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6940-6944
-
-
McDonnell, T.J.1
-
67
-
-
0030031962
-
Prostatic cell lineage markers: Emergence of BCL2+ cells of human prostate cancer xenograft LuCaP 23 following castration
-
Liu, A. Y., Corey, E., Bladou, F., Lange, P. H. & Vessella, R. L. Prostatic cell lineage markers: emergence of BCL2+ cells of human prostate cancer xenograft LuCaP 23 following castration. Int. J. Cancer 65, 85-89 (1996).
-
(1996)
Int. J. Cancer
, vol.65
, pp. 85-89
-
-
Liu, A.Y.1
Corey, E.2
Bladou, F.3
Lange, P.H.4
Vessella, R.L.5
-
68
-
-
78650016651
-
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
-
Tanaka, H. et al. Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat. Med. 16, 1414-1420 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 1414-1420
-
-
Tanaka, H.1
-
69
-
-
77953576511
-
N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer
-
Jennbacken, K. et al. N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer. Endocr. Relat. Cancer 17, 469-479 (2010).
-
(2010)
Endocr. Relat. Cancer
, vol.17
, pp. 469-479
-
-
Jennbacken, K.1
-
70
-
-
84862908058
-
Androgen deprivation causes epithelial-mesenchymal transition in the prostate: Implications for androgen-deprivation therapy
-
Sun, Y. et al. Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res. 72, 527-536 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 527-536
-
-
Sun, Y.1
-
71
-
-
46749135243
-
Hormone refractory prostate cancer: Lessons learned from the PTEN prostate cancer model
-
Mulholland, D. J., Jiao, J. & Wu, H. Hormone refractory prostate cancer: lessons learned from the PTEN prostate cancer model. Adv. Exp. Med. Biol. 617, 87-95 (2008).
-
(2008)
Adv. Exp. Med. Biol.
, vol.617
, pp. 87-95
-
-
Mulholland, D.J.1
Jiao, J.2
Wu, H.3
-
72
-
-
33749254070
-
Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer
-
Gao, H. et al. Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. Proc. Natl Acad. Sci. USA 103, 14477-14482 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 14477-14482
-
-
Gao, H.1
-
73
-
-
34447121369
-
Murine cell lines derived from Pten null prostate cancer show the critical role of PTEN in hormone refractory prostate cancer development
-
Jiao, J. et al. Murine cell lines derived from Pten null prostate cancer show the critical role of PTEN in hormone refractory prostate cancer development. Cancer Res. 67, 6083-6091 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 6083-6091
-
-
Jiao, J.1
-
74
-
-
79955975429
-
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
-
Carver, B. S. et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell 19, 575-586 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 575-586
-
-
Carver, B.S.1
-
75
-
-
79958764107
-
Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth
-
Mulholland, D. J. et al. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 19, 792-804 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 792-804
-
-
Mulholland, D.J.1
-
76
-
-
79956370342
-
Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal
-
Memarzadeh, S. et al. Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal. Proc. Natl Acad. Sci. USA 108, 7962-7967 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 7962-7967
-
-
Memarzadeh, S.1
-
77
-
-
77949379050
-
B-cell-derived lymphotoxin promotes castration-resistant prostate cancer
-
Ammirante, M., Luo, J.-L., Grivennikov, S., Nedospasov, S. & Karin, M. B-cell-derived lymphotoxin promotes castration-resistant prostate cancer. Nature 464, 302-305 (2010).
-
(2010)
Nature
, vol.464
, pp. 302-305
-
-
Ammirante, M.1
Luo, J.-L.2
Grivennikov, S.3
Nedospasov, S.4
Karin, M.5
-
78
-
-
0030727885
-
Androgen-independent prostate cancer progression in the TRAMP model
-
Gingrich, J. R. et al. Androgen-independent prostate cancer progression in the TRAMP model. Cancer Res. 57, 4687-4691 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 4687-4691
-
-
Gingrich, J.R.1
-
79
-
-
33748038440
-
Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice
-
Gao, H., Ouyang, X., Banach-Petrosky, W. A., Shen, M. M. & Abate-Shen, C. Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice. Cancer Res. 66, 7929-7933 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 7929-7933
-
-
Gao, H.1
Ouyang, X.2
Banach-Petrosky, W.A.3
Shen, M.M.4
Abate-Shen, C.5
-
80
-
-
0033215472
-
Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process
-
Craft, N. et al. Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process. Cancer Res. 59, 5030-5036 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 5030-5036
-
-
Craft, N.1
-
81
-
-
84861905616
-
Stem-like cells with luminal progenitor phenotype survive castration in human prostate cancer
-
Germann, M. et al. Stem-like cells with luminal progenitor phenotype survive castration in human prostate cancer. Stem Cells 30, 1076-1086 (2012).
-
(2012)
Stem Cells
, vol.30
, pp. 1076-1086
-
-
Germann, M.1
-
82
-
-
0034652723
-
Androgen receptor mutations in prostate cancer
-
Marcelli, M. et al. Androgen receptor mutations in prostate cancer. Cancer Res. 60, 944-949 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 944-949
-
-
Marcelli, M.1
-
83
-
-
0347364754
-
Androgen receptor mutations in high-grade prostate cancer before hormonal therapy
-
Thompson, J. et al. Androgen receptor mutations in high-grade prostate cancer before hormonal therapy. Lab. Invest. 83, 1709-1713 (2003).
-
(2003)
Lab. Invest.
, vol.83
, pp. 1709-1713
-
-
Thompson, J.1
-
84
-
-
77956615624
-
Primitive origins of prostate cancer: In vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells
-
Goldstein, A. S., Stoyanova, T. & Witte, O. N. Primitive origins of prostate cancer: in vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells. Mol. Oncol. 4, 385-396 (2010).
-
(2010)
Mol. Oncol.
, vol.4
, pp. 385-396
-
-
Goldstein, A.S.1
Stoyanova, T.2
Witte, O.N.3
-
85
-
-
0025650618
-
Immunohistochemical localization of the androgen receptor in rat and human tissues
-
Sar, M., Lubahn, D. B., French, F. S. & Wilson, E. M. Immunohistochemical localization of the androgen receptor in rat and human tissues. Endocrinology 127, 3180-3186 (1990).
-
(1990)
Endocrinology
, vol.127
, pp. 3180-3186
-
-
Sar, M.1
Lubahn, D.B.2
French, F.S.3
Wilson, E.M.4
-
86
-
-
0027458565
-
Widespread distribution of nuclear androgen receptors in the basal cell layer of the normal and hyperplastic human prostate
-
Bonkhoff, H. & Remberger, K. Widespread distribution of nuclear androgen receptors in the basal cell layer of the normal and hyperplastic human prostate. Virchows Arch. A Pathol. Anat. Histopathol. 422, 35-38 (1993).
-
(1993)
Virchows Arch. A Pathol. Anat. Histopathol.
, vol.422
, pp. 35-38
-
-
Bonkhoff, H.1
Remberger, K.2
-
87
-
-
77249178726
-
Basal epithelial stem cells are efficient targets for prostate cancer initiation
-
Lawson, D. A. et al. Basal epithelial stem cells are efficient targets for prostate cancer initiation. Proc. Natl Acad. Sci. USA 107 2610-2615 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 2610-2615
-
-
Lawson, D.A.1
-
88
-
-
0023901348
-
Activation of programmed cell death in the rat ventral prostate after castration
-
Kyprianou, N. & Isaacs, J. T. Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology 122, 552-562 (1988).
-
(1988)
Endocrinology
, vol.122
, pp. 552-562
-
-
Kyprianou, N.1
Isaacs, J.T.2
-
89
-
-
26844531799
-
Neuroendocrine cells in benign and malignant prostate tissue: Morphogenesis, proliferation, and androgen receptor status
-
Bonkhoff, H. Neuroendocrine cells in benign and malignant prostate tissue: morphogenesis, proliferation, and androgen receptor status. Prostate Suppl. 8, 18-22 (1998).
-
(1998)
Prostate Suppl.
, vol.8
, pp. 18-22
-
-
Bonkhoff, H.1
-
90
-
-
33748441022
-
Immunohistochemical characterization of neuroendocrine cells in prostate cancer
-
Huang, J. et al. Immunohistochemical characterization of neuroendocrine cells in prostate cancer. Prostate 66, 1399-1406 (2006).
-
(2006)
Prostate
, vol.66
, pp. 1399-1406
-
-
Huang, J.1
-
91
-
-
0035663808
-
Expression of basal cell keratins in human prostate cancer metastases and cell lines
-
van Leenders, G. J., Aalders, T. W., Hulsbergen-van de Kaa, C. A., Ruiter, D. J. & Schalken, J. A. Expression of basal cell keratins in human prostate cancer metastases and cell lines. J. Pathol. 195, 563-570 (2001).
-
(2001)
J. Pathol.
, vol.195
, pp. 563-570
-
-
Van Leenders, G.J.1
Aalders, T.W.2
Hulsbergen-Van De Kaa, C.A.3
Ruiter, D.J.4
Schalken, J.A.5
-
92
-
-
1842788109
-
Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy
-
Hirano, D., Okada, Y., Minei, S., Takimoto, Y. & Nemoto, N. Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy. Eur. Urol. 45 586-592 (2004).
-
(2004)
Eur. Urol.
, vol.45
, pp. 586-592
-
-
Hirano, D.1
Okada, Y.2
Minei, S.3
Takimoto, Y.4
Nemoto, N.5
-
93
-
-
70349438989
-
A luminal epithelial stem cell that is a cell of origin for prostate cancer
-
Wang, X. et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 461, 495-500 (2009).
-
(2009)
Nature
, vol.461
, pp. 495-500
-
-
Wang, X.1
-
94
-
-
21344454216
-
Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis
-
Ma, X. et al. Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis. Cancer Res. 65, 5730-5739 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 5730-5739
-
-
Ma, X.1
-
95
-
-
84863078902
-
Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation
-
Choi, N., Zhang, B., Zhang, L., Ittmann, M. & Xin, L. Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation. Cancer Cell 21, 253-265 (2012).
-
(2012)
Cancer Cell
, vol.21
, pp. 253-265
-
-
Choi, N.1
Zhang, B.2
Zhang, L.3
Ittmann, M.4
Xin, L.5
-
96
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein, A. S., Huang, J., Guo, C., Garraway, I. P. & Witte, O. N. Identification of a cell of origin for human prostate cancer. Science 329, 568-571 (2010).
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
Garraway, I.P.4
Witte, O.N.5
-
97
-
-
72249113369
-
Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model
-
Mulholland, D. J. et al. Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model. Cancer Res. 69, 8555-8562 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 8555-8562
-
-
Mulholland, D.J.1
-
98
-
-
84862650290
-
Pathogenesis of prostatic small cell carcinoma involves the inactivation of the p53 pathway
-
Chen, H. et al. Pathogenesis of prostatic small cell carcinoma involves the inactivation of the p53 pathway. Endocr. Relat. Cancer 19 321-331 (2012).
-
(2012)
Endocr. Relat. Cancer
, vol.19
, pp. 321-331
-
-
Chen, H.1
-
99
-
-
79958761641
-
Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung
-
Sutherland, K. D. et al. Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell 19, 754-764 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 754-764
-
-
Sutherland, K.D.1
-
100
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S. J., Clarke, M. F. & Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001).
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
101
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
Magee, J. A., Piskounova, E. & Morrison, S. J. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 21, 283-296 (2012).
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
102
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
Clevers, H. The cancer stem cell: premises, promises and challenges. Nat. Med. 17 313-319 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
103
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
Zhou, B. B. et al. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat. Rev. Drug Discov. 8 806-823 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
-
104
-
-
33644560281
-
Cancer stem cells: An old idea-a paradigm shift
-
Wicha, M. S., Liu, S. & Dontu, G. Cancer stem cells: an old idea-a paradigm shift. Cancer Res. 66, 1883-1896 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 1883-1896
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
-
105
-
-
22244433866
-
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
-
Patrawala, L. et al. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res. 65, 6207-6219 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 6207-6219
-
-
Patrawala, L.1
-
106
-
-
77953789724
-
High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer
-
van den Hoogen, C. et al. High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer. Cancer Res. 70 5163-5173 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5163-5173
-
-
Van Den Hoogen, C.1
-
107
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins, A. T., Berry, P. A., Hyde, C., Stower, M. J. & Maitland, N. J. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res. 65, 10946-10951 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
108
-
-
70349507504
-
Vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue
-
Guzmán-Ramirez, N. et al. In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue. Prostate 69, 1683-1693 (2009).
-
(2009)
Prostate
, vol.69
, pp. 1683-1693
-
-
Guzmán-Ramirez, N.1
-
109
-
-
34250315214
-
Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
-
Gu, G., Yuan, J., Wills, M. & Kasper, S. Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer Res. 67, 4807-4815 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 4807-4815
-
-
Gu, G.1
Yuan, J.2
Wills, M.3
Kasper, S.4
-
110
-
-
33645026803
-
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
-
Patrawala, L. et al. Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 25, 1696-1708 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 1696-1708
-
-
Patrawala, L.1
-
111
-
-
84861418291
-
Management of metastatic castration-resistant prostate cancer: Recent advances
-
Mukherji, D., Eichholz, A. & De Bono, J. S. Management of metastatic castration-resistant prostate cancer: recent advances. Drugs 72, 1011-1028 (2012).
-
(2012)
Drugs
, vol.72
, pp. 1011-1028
-
-
Mukherji, D.1
Eichholz, A.2
De Bono, J.S.3
|