The antimicrobial peptide LL-37 induces synthesis and release of cysteinyl leukotrienes from human eosinophils - Implications for asthma

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 68, Issue 3, 2013, Pages 304-311

  Sun, J ^a   Dahlen B ^b,c   Agerberth, B ^a   Haeggstrom J Z ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Centre for Allergy Research   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

asthma; cathelicidins; eosinophil cationic proteins; human primary eosinophils; leukotrienes

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CYTOSOLIC PHOSPHOLIPASE A2; EOSINOPHIL CATIONIC PROTEIN; FORMYLPEPTIDE RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 5; LEUKOTRIENE C4 SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDOLEUKOTRIENE;

ADULT; ARTICLE; ASTHMA; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; FEMALE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; WESTERN BLOTTING;

ADULT; ARACHIDONATE 5-LIPOXYGENASE; ASTHMA; CATHELICIDINS; CYSTEINE; EOSINOPHIL CATIONIC PROTEIN; EOSINOPHILS; FEMALE; GLUTATHIONE TRANSFERASE; GROUP IV PHOSPHOLIPASES A2; HUMANS; LEUKOTRIENES; LIPID METABOLISM; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LIPOXIN; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84873730627     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12087     Document Type: Article

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