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Volumn 33, Issue 1, 2013, Pages 27-45

An update for atypical haemolytic uraemic syndrome: Diagnosis and treatment. A consensus document

Author keywords

Atypical hemolytic uremic syndrome; Complement; Eculizumab; Thrombotic microangiopathy

Indexed keywords

ECULIZUMAB; MONOCLONAL ANTIBODY;

EID: 84873723582     PISSN: 02116995     EISSN: None     Source Type: Journal    
DOI: 10.3265/Nefrologia.pre2012.Nov.11781     Document Type: Review
Times cited : (119)

References (104)
  • 2
    • 84857442742 scopus 로고    scopus 로고
    • Management of hemolytic uremic syndrome
    • Loirat C, Saland J, Bitzan M. Management of hemolytic uremic syndrome. Presse Med 2012;41(3 Pt 2):e115-35.
    • (2012) Presse Med , vol.41 , Issue.3 PART 2
    • Loirat, C.1    Saland, J.2    Bitzan, M.3
  • 3
    • 33747159590 scopus 로고    scopus 로고
    • Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome
    • Caprioli J, Noris M, Brioschi S, Pianetti G, Castelletti F, Bettinaglio P, et al. Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood 2006;108(4):1267-79.
    • (2006) Blood , vol.108 , Issue.4 , pp. 1267-1279
    • Caprioli, J.1    Noris, M.2    Brioschi, S.3    Pianetti, G.4    Castelletti, F.5    Bettinaglio, P.6
  • 4
    • 84873709231 scopus 로고    scopus 로고
    • Alexion Pharmaceuticals I
    • Ficha técnica 2012
    • Alexion Pharmaceuticals I. Soliris (eculizumab). Ficha técnica 2012.
    • Soliris (eculizumab)
  • 5
    • 35948959015 scopus 로고    scopus 로고
    • Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria
    • Rother RP, Rollins SA, Mojcik CF, Brodsky RA, Bell L. Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria. Nat Biotechnol 2007;25(11):1256-64.
    • (2007) Nat Biotechnol , vol.25 , Issue.11 , pp. 1256-1264
    • Rother, R.P.1    Rollins, S.A.2    Mojcik, C.F.3    Brodsky, R.A.4    Bell, L.5
  • 6
    • 84866047891 scopus 로고    scopus 로고
    • Eculizumab Is An Effective Long-Term Treatment In Patients with Atypical Hemolytic Uremic Syndrome (aHUS) Previously Receiving Chronic Plasma Exchange/Infusion (PE/PI): Extension Study Results
    • abstr 3303
    • Licht C, Muus P, Legendre C, Douglas KW, Hourmant M, Delmas Y, et al. Eculizumab Is An Effective Long-Term Treatment In Patients with Atypical Hemolytic Uremic Syndrome (aHUS) Previously Receiving Chronic Plasma Exchange/Infusion (PE/PI): Extension Study Results. Blood 2011;118(21):abstr 3303.
    • (2011) Blood , vol.118 , Issue.21
    • Licht, C.1    Muus, P.2    Legendre, C.3    Douglas, K.W.4    Hourmant, M.5    Delmas, Y.6
  • 7
    • 84862244283 scopus 로고    scopus 로고
    • Eculizumab Is An Effective Long-Term Treatment In Patients with Atypical Hemolytic Uremic Syndrome (aHUS) Resistant to Plasma Exchange/Infusion (PE/PI): Results of An Extension Study
    • abstr 193
    • Greenbaum L, Babu S, Furman RR, Sheerin N, Cohen D, Gaber O, et al. Eculizumab Is An Effective Long-Term Treatment In Patients with Atypical Hemolytic Uremic Syndrome (aHUS) Resistant to Plasma Exchange/Infusion (PE/PI): Results of An Extension Study. Blood 2011;118(21):abstr 193.
    • (2011) Blood , vol.118 , Issue.21
    • Greenbaum, L.1    Babu, S.2    Furman, R.R.3    Sheerin, N.4    Cohen, D.5    Gaber, O.6
  • 8
    • 84863981968 scopus 로고    scopus 로고
    • Continued improvements in renal function with sustained eculizumab (ECU) in patients (PTS) with atypical hemolytic uremic syndrome (aHUS) resistant to plasma exchange/infusion (PE/PI)
    • 197A abstr TH PO367
    • Greenbaum LA, Babu S, Furman R, Sheerin N, Cohen D, Gaber O, et al. Continued improvements in renal function with sustained eculizumab (ECU) in patients (PTS) with atypical hemolytic uremic syndrome (aHUS) resistant to plasma exchange/infusion (PE/PI). J Am Soc Nephrol 2011;22(suppl):197A abstr TH PO367.
    • (2011) J Am Soc Nephrol , vol.22 , Issue.SUPPL.
    • Greenbaum, L.A.1    Babu, S.2    Furman, R.3    Sheerin, N.4    Cohen, D.5    Gaber, O.6
  • 9
    • 84863981968 scopus 로고    scopus 로고
    • Ph II study of eculizumab (ECU) in patients (PTS) with atypical hemolytic uremic syndrome (aHUS) receiving chronic plasma exchange/infusion (PE/PI)
    • 197A abstr TH PO366
    • Licht C, Muus P, Legendre CM, Douglas K, Hourmant M, Delmas Y, et al. Ph II study of eculizumab (ECU) in patients (PTS) with atypical hemolytic uremic syndrome (aHUS) receiving chronic plasma exchange/infusion (PE/PI). J Am Soc Nephrol 2011;22(suppl):197A abstr TH PO366.
    • (2011) J Am Soc Nephrol , vol.22 , Issue.SUPPL.
    • Licht, C.1    Muus, P.2    Legendre, C.M.3    Douglas, K.4    Hourmant, M.5    Delmas, Y.6
  • 10
    • 0029925856 scopus 로고    scopus 로고
    • Partial purificatiion and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis
    • Furlan M, Robles N, Lammle B. Partial purificatiion and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis. Blood 1996;87:4223-34.
    • (1996) Blood , vol.87 , pp. 4223-4234
    • Furlan, M.1    Robles, N.2    Lammle, B.3
  • 11
    • 0034948863 scopus 로고    scopus 로고
    • Drug-induced thrombotic microangiopathy: incidence, prevention and management
    • Pisoni R, Ruggenenti P, Remuzzi G. Drug-induced thrombotic microangiopathy: incidence, prevention and management. Drug Saf 2001;24(7):491-501.
    • (2001) Drug Saf , vol.24 , Issue.7 , pp. 491-501
    • Pisoni, R.1    Ruggenenti, P.2    Remuzzi, G.3
  • 12
    • 17144365102 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome; pathogenesis, treatment, and outcome
    • Siegler R, Oakes R. Hemolytic uremic syndrome; pathogenesis, treatment, and outcome. Curr Opin Pediatr 2005;17(2):200-4.
    • (2005) Curr Opin Pediatr , vol.17 , Issue.2 , pp. 200-204
    • Siegler, R.1    Oakes, R.2
  • 15
    • 77958587405 scopus 로고    scopus 로고
    • Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
    • Noris M, Caprioli J, Bresin E, Mossali C, Pianetti G, Gamba S, et al. Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol 2010;5(10):1844-59.
    • (2010) Clin J Am Soc Nephrol , vol.5 , Issue.10 , pp. 1844-1859
    • Noris, M.1    Caprioli, J.2    Bresin, E.3    Mossali, C.4    Pianetti, G.5    Gamba, S.6
  • 16
    • 72549097037 scopus 로고    scopus 로고
    • Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome
    • Sullivan M, Erlic Z, Hoffmann MM, Arbeiter K, Patzer L, Budde K, et al. Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome. Ann Hum Genet 2010;74(1):17-26.
    • (2010) Ann Hum Genet , vol.74 , Issue.1 , pp. 17-26
    • Sullivan, M.1    Erlic, Z.2    Hoffmann, M.M.3    Arbeiter, K.4    Patzer, L.5    Budde, K.6
  • 17
    • 77954328285 scopus 로고    scopus 로고
    • Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS)
    • Westra D, Volokhina E, van der Heijden E, Vos A, Huigen M, Jansen J, et al. Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS). Nephrol Dial Transplant 2010;25(7):2195-202.
    • (2010) Nephrol Dial Transplant , vol.25 , Issue.7 , pp. 2195-2202
    • Westra, D.1    Volokhina, E.2    van der Heijden, E.3    Vos, A.4    Huigen, M.5    Jansen, J.6
  • 18
    • 14644424005 scopus 로고    scopus 로고
    • Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complementactivation gene cluster in 1q32
    • Esparza-Gordillo J, Goicoechea de Jorge E, Buil A, Carreras Berges L, López-Trascasa M, Sánchez-Corral P, et al. Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complementactivation gene cluster in 1q32. Hum Mol Genet 2005;14(5):703-12.
    • (2005) Hum Mol Genet , vol.14 , Issue.5 , pp. 703-712
    • Esparza-Gordillo, J.1    Goicoechea de Jorge, E.2    Buil, A.3    Carreras Berges, L.4    López-Trascasa, M.5    Sánchez-Corral, P.6
  • 19
    • 67650508077 scopus 로고    scopus 로고
    • The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome
    • Dragon-Durey MA, Blanc C, Marliot F, Loirat C, Blouin J, Sautes-Fridman C, et al. The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome. J Med Genet 2009;46(7):447-50.
    • (2009) J Med Genet , vol.46 , Issue.7 , pp. 447-450
    • Dragon-Durey, M.A.1    Blanc, C.2    Marliot, F.3    Loirat, C.4    Blouin, J.5    Sautes-Fridman, C.6
  • 20
    • 75749153964 scopus 로고    scopus 로고
    • Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome
    • Bienaime F, Dragon-Durey MA, Regnier CH, Nilsson SC, Kwan WH, Blouin J, et al. Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome. Kidney Int 2010;77(4):339-49.
    • (2010) Kidney Int , vol.77 , Issue.4 , pp. 339-349
    • Bienaime, F.1    Dragon-Durey, M.A.2    Regnier, C.H.3    Nilsson, S.C.4    Kwan, W.H.5    Blouin, J.6
  • 21
    • 77952682366 scopus 로고    scopus 로고
    • Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome
    • Maga TK, Nishimura CJ, Weaver AE, Frees KL, Smith RJ. Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. Hum Mutat 2010;31(6):E1445-60.
    • (2010) Hum Mutat , vol.31 , Issue.6
    • Maga, T.K.1    Nishimura, C.J.2    Weaver, A.E.3    Frees, K.L.4    Smith, R.J.5
  • 22
    • 78649863686 scopus 로고    scopus 로고
    • Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome
    • Dragon-Durey MA, Sethi SK, Bagga A, Blanc C, Blouin J, Ranchin B, et al. Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome. J Am Soc Nephrol 2010;21(12): 2180-7.
    • (2010) J Am Soc Nephrol , vol.21 , Issue.12 , pp. 2180-2187
    • Dragon-Durey, M.A.1    Sethi, S.K.2    Bagga, A.3    Blanc, C.4    Blouin, J.5    Ranchin, B.6
  • 23
    • 36048948905 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome (HUS) secondary to cobalamin C (cblC) disorder
    • Sharma AP, Greenberg CR, Prasad AN, Prasad C. Hemolytic uremic syndrome (HUS) secondary to cobalamin C (cblC) disorder. Pediatr Nephrol 2007;22(12):2097-103.
    • (2007) Pediatr Nephrol , vol.22 , Issue.12 , pp. 2097-2103
    • Sharma, A.P.1    Greenberg, C.R.2    Prasad, A.N.3    Prasad, C.4
  • 24
    • 34447539658 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome associated with invasive pneumococcal disease: the United kingdom experience
    • Waters AM, Kerecuk L, Luk D, Haq MR, Fitzpatrick MM, Gilbert RD, et al. Hemolytic uremic syndrome associated with invasive pneumococcal disease: the United kingdom experience. J Pediatr 2007;151(2):140-4.
    • (2007) J Pediatr , vol.151 , Issue.2 , pp. 140-144
    • Waters, A.M.1    Kerecuk, L.2    Luk, D.3    Haq, M.R.4    Fitzpatrick, M.M.5    Gilbert, R.D.6
  • 25
    • 79952998614 scopus 로고    scopus 로고
    • Pandemic H1N1 influenza A infection and (atypical) HUS-more than just another trigger?
    • Allen U, Licht C. Pandemic H1N1 influenza A infection and (atypical) HUS-more than just another trigger? Pediatr Nephrol 2011;26(1):3-5.
    • (2011) Pediatr Nephrol , vol.26 , Issue.1 , pp. 3-5
    • Allen, U.1    Licht, C.2
  • 26
    • 33746508999 scopus 로고    scopus 로고
    • A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders
    • Besbas N, Karpman D, Landau D, Loirat C, Proesmans W, Remuzzi G, et al. A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders. Kidney Int 2006;70(3):423-31.
    • (2006) Kidney Int , vol.70 , Issue.3 , pp. 423-431
    • Besbas, N.1    Karpman, D.2    Landau, D.3    Loirat, C.4    Proesmans, W.5    Remuzzi, G.6
  • 27
    • 77957587756 scopus 로고    scopus 로고
    • Treatment of typical (enteropathic) hemolytic uremic syndrome
    • Bitzan M, Schaefer F, Reymond D. Treatment of typical (enteropathic) hemolytic uremic syndrome. Semin Thromb Hemost 2010;36(6):594-610.
    • (2010) Semin Thromb Hemost , vol.36 , Issue.6 , pp. 594-610
    • Bitzan, M.1    Schaefer, F.2    Reymond, D.3
  • 28
    • 77952556624 scopus 로고    scopus 로고
    • Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations
    • Fakhouri F, Roumenina L, Provot F, Sallée M, Caillard S, Couzi L, et al. Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol 2010;21(5):859-67.
    • (2010) J Am Soc Nephrol , vol.21 , Issue.5 , pp. 859-867
    • Fakhouri, F.1    Roumenina, L.2    Provot, F.3    Sallée, M.4    Caillard, S.5    Couzi, L.6
  • 30
    • 0030785590 scopus 로고    scopus 로고
    • Heterogeneity of atypical haemolytic uraemic syndromes
    • Neuhaus TJ, Calonder S, Leumann EP. Heterogeneity of atypical haemolytic uraemic syndromes. Arch Dis Child 1997;76(6):518-21.
    • (1997) Arch Dis Child , vol.76 , Issue.6 , pp. 518-521
    • Neuhaus, T.J.1    Calonder, S.2    Leumann, E.P.3
  • 31
    • 81255130615 scopus 로고    scopus 로고
    • Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome
    • Ohanian M, Cable C, Halka K. Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome. Clin Pharmacol 2011;3:5-12.
    • (2011) Clin Pharmacol , vol.3 , pp. 5-12
    • Ohanian, M.1    Cable, C.2    Halka, K.3
  • 33
    • 53749084348 scopus 로고    scopus 로고
    • Complement and the atypical hemolytic uremic syndrome in children
    • Loirat C, Noris M, Fremeaux-Bacchi V. Complement and the atypical hemolytic uremic syndrome in children. Pediatr Nephrol 2008;23(11):1957-72.
    • (2008) Pediatr Nephrol , vol.23 , Issue.11 , pp. 1957-1972
    • Loirat, C.1    Noris, M.2    Fremeaux-Bacchi, V.3
  • 34
    • 0033869032 scopus 로고    scopus 로고
    • Peripheral gangrene complicating idiopathic and recessive hemolytic uremic syndromes
    • Kaplan BS, Garcia CD, Chesney RW, Segar WE, Giugno K, Chem R. Peripheral gangrene complicating idiopathic and recessive hemolytic uremic syndromes. Pediatr Nephrol 2000;14(10-11):985-9.
    • (2000) Pediatr Nephrol , vol.14 , Issue.10-11 , pp. 985-989
    • Kaplan, B.S.1    Garcia, C.D.2    Chesney, R.W.3    Segar, W.E.4    Giugno, K.5    Chem, R.6
  • 37
    • 0035143299 scopus 로고    scopus 로고
    • The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20
    • Caprioli J, Bettinaglio P, Zipfel PF, Amadei B, Daina E, Gamba S, et al. The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20. J Am Soc Nephrol 2001;12(2):297-307.
    • (2001) J Am Soc Nephrol , vol.12 , Issue.2 , pp. 297-307
    • Caprioli, J.1    Bettinaglio, P.2    Zipfel, P.F.3    Amadei, B.4    Daina, E.5    Gamba, S.6
  • 39
    • 33745812440 scopus 로고    scopus 로고
    • Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome
    • Fremeaux-Bacchi V, Moulton EA, Kavanagh D, Dragon-Durey MA, Blouin J, Caudy A, et al. Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. J Am Soc Nephrol 2006;17(7):2017-25.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.7 , pp. 2017-2025
    • Fremeaux-Bacchi, V.1    Moulton, E.A.2    Kavanagh, D.3    Dragon-Durey, M.A.4    Blouin, J.5    Caudy, A.6
  • 40
    • 54049137505 scopus 로고    scopus 로고
    • Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
    • Fremeaux-Bacchi V, Miller EC, Liszewski MK, Strain L, Blouin J, Brown AL, et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood 2008;112(13):4948-52.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4948-4952
    • Fremeaux-Bacchi, V.1    Miller, E.C.2    Liszewski, M.K.3    Strain, L.4    Blouin, J.5    Brown, A.L.6
  • 42
    • 27744452766 scopus 로고    scopus 로고
    • Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome
    • Kavanagh D, Kemp EJ, Mayland E, Winney RJ, Duffield JS, Warwick G, et al. Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome. J Am Soc Nephrol 2005;16(7):2150-5.
    • (2005) J Am Soc Nephrol , vol.16 , Issue.7 , pp. 2150-2155
    • Kavanagh, D.1    Kemp, E.J.2    Mayland, E.3    Winney, R.J.4    Duffield, J.S.5    Warwick, G.6
  • 45
    • 0035128326 scopus 로고    scopus 로고
    • Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition
    • Richards A, Buddles MR, Donne RL, Kaplan BS, Kirk E, Venning MC, et al. Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition. Am J Hum Genet 2001;68(2):485-90.
    • (2001) Am J Hum Genet , vol.68 , Issue.2 , pp. 485-490
    • Richards, A.1    Buddles, M.R.2    Donne, R.L.3    Kaplan, B.S.4    Kirk, E.5    Venning, M.C.6
  • 46
    • 0242331610 scopus 로고    scopus 로고
    • Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome
    • Richards A, Kemp EJ, Liszewski MK, Goodship JA, Lampe AK, Decorte R, et al. Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. Proc Natl Acad Sci U S A 2003;100(22):12966-71.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.22 , pp. 12966-12971
    • Richards, A.1    Kemp, E.J.2    Liszewski, M.K.3    Goodship, J.A.4    Lampe, A.K.5    Decorte, R.6
  • 47
    • 36849084660 scopus 로고    scopus 로고
    • Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H
    • de Córdoba SR, de Jorge EG. Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H. Clin Exp Immunol 2008;151(1):1-13.
    • (2008) Clin Exp Immunol , vol.151 , Issue.1 , pp. 1-13
    • de Córdoba, S.R.1    de Jorge, E.G.2
  • 49
    • 34548853385 scopus 로고    scopus 로고
    • Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome
    • Jozsi M, Strobel S, Dahse H-M, Liu WS, Hoyer PF, Oppermann M, et al. Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome. Blood2007;110(5):1516-8.
    • (2007) Blood , vol.110 , Issue.5 , pp. 1516-1518
    • Jozsi, M.1    Strobel, S.2    Dahse, H.-M.3    Liu, W.S.4    Hoyer, P.F.5    Oppermann, M.6
  • 50
    • 0242601270 scopus 로고    scopus 로고
    • Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease
    • Caprioli J, Castelletti F, Bucchioni S, Bettinaglio P, Bresin E, Pianetti G, et al. Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum Mol Genet 2003;12(24):3385-95.
    • (2003) Hum Mol Genet , vol.12 , Issue.24 , pp. 3385-3395
    • Caprioli, J.1    Castelletti, F.2    Bucchioni, S.3    Bettinaglio, P.4    Bresin, E.5    Pianetti, G.6
  • 51
    • 33644964155 scopus 로고    scopus 로고
    • Insights into hemolytic uremic syndrome: Segregation of three independent predisposition factors in a large, multiple affected pedigree
    • Esparza-Gordillo J, Jorge EGd, Garrido CA, Carreras L, López-Trascasa M, Sánchez-Corral P, et al. Insights into hemolytic uremic syndrome: Segregation of three independent predisposition factors in a large, multiple affected pedigree. Mol Immunol 2006;43(11):1769-75.
    • (2006) Mol Immunol , vol.43 , Issue.11 , pp. 1769-1775
    • Esparza-Gordillo, J.1    Jorge, E.G.2    Garrido, C.A.3    Carreras, L.4    López-Trascasa, M.5    Sánchez-Corral, P.6
  • 52
    • 34548400755 scopus 로고    scopus 로고
    • Outcome of renal transplantation in patients with non-Shiga toxinassociated hemolytic uremic syndrome: prognostic significance of genetic background
    • Bresin E, Daina E, Noris M, Castelletti F, Stefanov R, Hill P, et al. Outcome of renal transplantation in patients with non-Shiga toxinassociated hemolytic uremic syndrome: prognostic significance of genetic background. Clin J Am Soc Nephrol 2006;1(1):88-9.
    • (2006) Clin J Am Soc Nephrol , vol.1 , Issue.1 , pp. 88-89
    • Bresin, E.1    Daina, E.2    Noris, M.3    Castelletti, F.4    Stefanov, R.5    Hill, P.6
  • 53
    • 49349112382 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome recurrence after renal transplantation
    • Loirat C, Fremeaux-Bacchi V. Hemolytic uremic syndrome recurrence after renal transplantation. Pediatr Transplant 2008;12(6):619-29.
    • (2008) Pediatr Transplant , vol.12 , Issue.6 , pp. 619-629
    • Loirat, C.1    Fremeaux-Bacchi, V.2
  • 55
    • 70350475255 scopus 로고    scopus 로고
    • Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome
    • Roumenina LT, Jablonski M, Hue C, Blouin J, Dimitrov JD, Dragon- Durey MA, et al. Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. Blood 2009;114(13):2837-45.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2837-2845
    • Roumenina, L.T.1    Jablonski, M.2    Hue, C.3    Blouin, J.4    Dimitrov, J.D.5    Dragon-Durey, M.A.6
  • 57
    • 65249156546 scopus 로고    scopus 로고
    • Anti-Factor H autoantibodies in a fifth renal transplant recipient with atypical hemolytic and uremic syndrome
    • Le Quintrec M, Zuber J, Noel LH, Thervet E, Frémeaux-Bacchi V, Niaudet P, et al. Anti-Factor H autoantibodies in a fifth renal transplant recipient with atypical hemolytic and uremic syndrome. Am J Transplant 2009;9(5):1223-9.
    • (2009) Am J Transplant , vol.9 , Issue.5 , pp. 1223-1229
    • Le Quintrec, M.1    Zuber, J.2    Noel, L.H.3    Thervet, E.4    Frémeaux-Bacchi, V.5    Niaudet, P.6
  • 58
    • 0346786465 scopus 로고    scopus 로고
    • Morphologic diagnosis of thrombotic thrombocytopenic purpura
    • Burns ER, Lou Y, Pathak A. Morphologic diagnosis of thrombotic thrombocytopenic purpura. Am J Hematol 2004;75(1):18-21.
    • (2004) Am J Hematol , vol.75 , Issue.1 , pp. 18-21
    • Burns, E.R.1    Lou, Y.2    Pathak, A.3
  • 59
    • 34548778614 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome: much progress and many remaining issues
    • Mannucci PM. Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome: much progress and many remaining issues. Haematologica 2007;92(7):878-80.
    • (2007) Haematologica , vol.92 , Issue.7 , pp. 878-880
    • Mannucci, P.M.1
  • 60
    • 73349123465 scopus 로고    scopus 로고
    • Pathophysiology of thrombotic thrombocytopenic purpura
    • Tsai HM. Pathophysiology of thrombotic thrombocytopenic purpura. Int J Hematol 2010;91(1):1-19.
    • (2010) Int J Hematol , vol.91 , Issue.1 , pp. 1-19
    • Tsai, H.M.1
  • 62
    • 61549117207 scopus 로고    scopus 로고
    • Guideline for the investigation and initial therapy of diarrheanegative hemolytic uremic syndrome
    • Ariceta G, Besbas N, Johnson S, Karpman D, Landau D, Licht C, et al. Guideline for the investigation and initial therapy of diarrheanegative hemolytic uremic syndrome. Pediatr Nephrol 2009;24(4):687-96.
    • (2009) Pediatr Nephrol , vol.24 , Issue.4 , pp. 687-696
    • Ariceta, G.1    Besbas, N.2    Johnson, S.3    Karpman, D.4    Landau, D.5    Licht, C.6
  • 63
    • 77951621575 scopus 로고    scopus 로고
    • Pulse cyclophosphamide therapy and clinical remission in atypical hemolytic uremic syndrome with anti-complement factor H autoantibodies
    • Boyer O, Balzamo E, Charbit M, Biebuyck-Gougé N, Salomon R, Dragon-Durey MA, et al. Pulse cyclophosphamide therapy and clinical remission in atypical hemolytic uremic syndrome with anti-complement factor H autoantibodies. Am J Kidney Dis 2010;55(5):923-7.
    • (2010) Am J Kidney Dis , vol.55 , Issue.5 , pp. 923-927
    • Boyer, O.1    Balzamo, E.2    Charbit, M.3    Biebuyck-Gougé, N.4    Salomon, R.5    Dragon-Durey, M.A.6
  • 64
    • 77955803613 scopus 로고    scopus 로고
    • A case of adult atypical haemolytic uraemic syndrome related to antifactor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
    • Lionet A, Provôt F, Glowacki F, Frémeaux-Bacchi V, Hazzan M. A case of adult atypical haemolytic uraemic syndrome related to antifactor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab. NDT Plus 2009;2:458.
    • (2009) NDT Plus , vol.2 , pp. 458
    • Lionet, A.1    Provôt, F.2    Glowacki, F.3    Frémeaux-Bacchi, V.4    Hazzan, M.5
  • 66
    • 59449088846 scopus 로고    scopus 로고
    • Eculizumab for congenital atypical hemolytic-uremic syndrome
    • Gruppo RA, Rother RP. Eculizumab for congenital atypical hemolytic-uremic syndrome. N Engl J Med 2009;360(5):544-6.
    • (2009) N Engl J Med , vol.360 , Issue.5 , pp. 544-546
    • Gruppo, R.A.1    Rother, R.P.2
  • 67
    • 83155172386 scopus 로고    scopus 로고
    • Eculizumab in atypical hemolytic uremic syndrome: long-term clinical course and histological findings
    • Tschumi S, Gugger M, Bucher BS, Riedl M, Simonetti GD. Eculizumab in atypical hemolytic uremic syndrome: long-term clinical course and histological findings. Pediatr Nephrol 2011;26(11):2085-8.
    • (2011) Pediatr Nephrol , vol.26 , Issue.11 , pp. 2085-2088
    • Tschumi, S.1    Gugger, M.2    Bucher, B.S.3    Riedl, M.4    Simonetti, G.D.5
  • 69
    • 78650507665 scopus 로고    scopus 로고
    • Eculizumab: safety and efficacy after 17 months of treatment in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome: case report
    • Chatelet V, Lobbedez T, Fremeaux-Bacchi V, Ficheux M, Ryckelynck JP, Hurault de Ligny B. Eculizumab: safety and efficacy after 17 months of treatment in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome: case report. Transplant Proc 2010;42(10):4353-5.
    • (2010) Transplant Proc , vol.42 , Issue.10 , pp. 4353-4355
    • Chatelet, V.1    Lobbedez, T.2    Fremeaux-Bacchi, V.3    Ficheux, M.4    Ryckelynck, J.P.5    Hurault de Ligny, B.6
  • 70
    • 84873734682 scopus 로고    scopus 로고
    • Successful Treatment of aHUS Recurrence and Arrest of Plasma Exchange Resistant TMA Post-Renal Transplantation with the Terminal Complement Inhibitor Eculizumab
    • abstr 2421
    • Legault DJ, Boelkins MR. Successful Treatment of aHUS Recurrence and Arrest of Plasma Exchange Resistant TMA Post-Renal Transplantation with the Terminal Complement Inhibitor Eculizumab. Blood 2009;114(22):abstr 2421.
    • (2009) Blood , vol.114 , Issue.22
    • Legault, D.J.1    Boelkins, M.R.2
  • 71
    • 77949570344 scopus 로고    scopus 로고
    • Maintenance of kidney function following treatment with eculizumab and discontinuation of plasma exchange after a third kidney transplant for atypical hemolytic uremic syndrome associated with a CFH mutation
    • Davin JC, Gracchi V, Bouts A, Groothoff J, Strain L, Goodship T. Maintenance of kidney function following treatment with eculizumab and discontinuation of plasma exchange after a third kidney transplant for atypical hemolytic uremic syndrome associated with a CFH mutation. Am J Kidney Dis 2010;55(4):708-11.
    • (2010) Am J Kidney Dis , vol.55 , Issue.4 , pp. 708-711
    • Davin, J.C.1    Gracchi, V.2    Bouts, A.3    Groothoff, J.4    Strain, L.5    Goodship, T.6
  • 72
    • 77951876953 scopus 로고    scopus 로고
    • Prophylactic eculizumab after renal transplantation in atypical hemolytic-uremic syndrome
    • Zimmerhackl LB, Hofer J, Cortina G, Mark W, Würzner R, Jungraithmayr TC, et al. Prophylactic eculizumab after renal transplantation in atypical hemolytic-uremic syndrome. N Engl J Med 2010;362(18):1746-8.
    • (2010) N Engl J Med , vol.362 , Issue.18 , pp. 1746-1748
    • Zimmerhackl, L.B.1    Hofer, J.2    Cortina, G.3    Mark, W.4    Würzner, R.5    Jungraithmayr, T.C.6
  • 73
    • 80052473232 scopus 로고    scopus 로고
    • Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome
    • Weitz M, Amon O, Bassler D, Koenigsrainer A, Nadalin S. Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome. Pediatr Nephrol 2011;26(8):1325-9.
    • (2011) Pediatr Nephrol , vol.26 , Issue.8 , pp. 1325-1329
    • Weitz, M.1    Amon, O.2    Bassler, D.3    Koenigsrainer, A.4    Nadalin, S.5
  • 74
    • 79958202220 scopus 로고    scopus 로고
    • Preemptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome
    • Nester C, Stewart Z, Myers D, Jetton J, Nair R, Reed A, et al. Preemptive eculizumab and plasmapheresis for renal transplant in atypical hemolytic uremic syndrome. Clin J Am Soc Nephrol 2011;6(6):1488-94.
    • (2011) Clin J Am Soc Nephrol , vol.6 , Issue.6 , pp. 1488-1494
    • Nester, C.1    Stewart, Z.2    Myers, D.3    Jetton, J.4    Nair, R.5    Reed, A.6
  • 75
    • 84868003869 scopus 로고    scopus 로고
    • Rescue therapy with eculizumab in a transplant recipient with atypical haemolytic uremic syndrome
    • Durán CE, Blasco M, Maduell F, Campistol JM. Rescue therapy with eculizumab in a transplant recipient with atypical haemolytic uremic syndrome. Clin Kidney J 2012;5(1):28-30.
    • (2012) Clin Kidney J , vol.5 , Issue.1 , pp. 28-30
    • Durán, C.E.1    Blasco, M.2    Maduell, F.3    Campistol, J.M.4
  • 76
    • 84873739044 scopus 로고    scopus 로고
    • Long-Term Outcome in a Pediatric Patient with Atypical Hemolytic Uremic Syndrome (aHUS) with Sustained Eculizumab (ECU) Treatment
    • abstr 4682
    • Gruppo RA, Dixon BP. Long-Term Outcome in a Pediatric Patient with Atypical Hemolytic Uremic Syndrome (aHUS) with Sustained Eculizumab (ECU) Treatment. Blood 2011;118(21):abstr 4682.
    • (2011) Blood , vol.118 , Issue.21
    • Gruppo, R.A.1    Dixon, B.P.2
  • 77
    • 84873732941 scopus 로고    scopus 로고
    • Eculizumab Treatment for aHUS in a Child with Positive Family History
    • 988A abstr PUB715
    • Fremont OT, Gordon CA, Hand MM. Eculizumab Treatment for aHUS in a Child with Positive Family History. J Am Soc Nephrol 2009;20(suppl):988A abstr PUB715.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.SUPPL.
    • Fremont, O.T.1    Gordon, C.A.2    Hand, M.M.3
  • 79
    • 77957602105 scopus 로고    scopus 로고
    • New treatment options for atypical hemolytic uremic syndrome with the complement inhibitor eculizumab
    • Kose O, Zimmerhackl LB, Jungraithmayr T, Mache C, Nurnberger J. New treatment options for atypical hemolytic uremic syndrome with the complement inhibitor eculizumab. Semin Thromb Hemost 2010;36(6):669-72.
    • (2010) Semin Thromb Hemost , vol.36 , Issue.6 , pp. 669-672
    • Kose, O.1    Zimmerhackl, L.B.2    Jungraithmayr, T.3    Mache, C.4    Nurnberger, J.5
  • 80
    • 79954433046 scopus 로고    scopus 로고
    • Efficacy of eculizumab in a patient with factor-H-associated atypical hemolytic uremic syndrome
    • Lapeyraque AL, Fremeaux-Bacchi V, Robitaille P. Efficacy of eculizumab in a patient with factor-H-associated atypical hemolytic uremic syndrome. Pediatr Nephrol 2011;26(4):621-4.
    • (2011) Pediatr Nephrol , vol.26 , Issue.4 , pp. 621-624
    • Lapeyraque, A.L.1    Fremeaux-Bacchi, V.2    Robitaille, P.3
  • 81
    • 78649513705 scopus 로고    scopus 로고
    • Eculizumabtherapy in an adult with plasma exchange-refractory atypical hemolytic uremic syndrome
    • Prescott HC, Wu HM, Cataland SR, Baiocchi RA. Eculizumabtherapy in an adult with plasma exchange-refractory atypical hemolytic uremic syndrome. Am J Hematol 2010;85(12):976-7.
    • (2010) Am J Hematol , vol.85 , Issue.12 , pp. 976-977
    • Prescott, H.C.1    Wu, H.M.2    Cataland, S.R.3    Baiocchi, R.A.4
  • 82
    • 81255195666 scopus 로고    scopus 로고
    • Reduced dose maintenance eculizumab in atypical hemolytic uremic syndrome (aHUS): an update on a previous case report
    • Ohanian M, Cable C, Halka K. Reduced dose maintenance eculizumab in atypical hemolytic uremic syndrome (aHUS): an update on a previous case report. Clin Pharmacol 2011;3:45-50.
    • (2011) Clin Pharmacol , vol.3 , pp. 45-50
    • Ohanian, M.1    Cable, C.2    Halka, K.3
  • 83
    • 70350130833 scopus 로고    scopus 로고
    • Safety and long-term efficacy of eculizumab in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome
    • Chatelet V, Fremeaux-Bacchi V, Lobbedez T, Ficheux M, Hurault de Ligny B. Safety and long-term efficacy of eculizumab in a renal transplant patient with recurrent atypical hemolytic-uremic syndrome. Am J Transplant 2009;9(11):2644-5.
    • (2009) Am J Transplant , vol.9 , Issue.11 , pp. 2644-2645
    • Chatelet, V.1    Fremeaux-Bacchi, V.2    Lobbedez, T.3    Ficheux, M.4    Hurault de Ligny, B.5
  • 84
    • 84879321491 scopus 로고    scopus 로고
    • Long-term eculizumab improves clinical outcomes in atypical hemolytic uremic syndrome
    • Vilalta R, Lara E, Madrid A, Chocron S, Muñoz M, Casquero A, et al. Long-term eculizumab improves clinical outcomes in atypical hemolytic uremic syndrome. Pediatr Nephrol 2012;27(12):2323-6.
    • (2012) Pediatr Nephrol , vol.27 , Issue.12 , pp. 2323-2326
    • Vilalta, R.1    Lara, E.2    Madrid, A.3    Chocron, S.4    Muñoz, M.5    Casquero, A.6
  • 85
    • 79955043199 scopus 로고    scopus 로고
    • Safety and efficacy of eculizumab in aHUS patients resistant to plasma therapy: interim analysis from a phase II trial
    • 93A abstr SA FC406
    • Legendre CM, Babu S, Furman R, Sheerin N, Cohen D, Gaber OÅ, et al. Safety and efficacy of eculizumab in aHUS patients resistant to plasma therapy: interim analysis from a phase II trial. J Am Soc Nephrol 2010;21(suppl):93A abstr SA FC406.
    • (2010) J Am Soc Nephrol , vol.21 , Issue.SUPPL.
    • Legendre, C.M.1    Babu, S.2    Furman, R.3    Sheerin, N.4    Cohen, D.5    Gaber, O.Å.6
  • 86
    • 79955043199 scopus 로고    scopus 로고
    • Safety and efficacy of eculizumab in aHUS patients on chronic plasma therapy: interim analysis of a phase II trial
    • 402A abstr FH PO1274
    • Muus P, Legendre CM, Douglas K, Hourmant M, Delmas Y, Herthelius B, et al. Safety and efficacy of eculizumab in aHUS patients on chronic plasma therapy: interim analysis of a phase II trial. J Am Soc Nephrol 2010;21(suppl):402A abstr FH PO1274.
    • (2010) J Am Soc Nephrol , vol.21 , Issue.SUPPL.
    • Muus, P.1    Legendre, C.M.2    Douglas, K.3    Hourmant, M.4    Delmas, Y.5    Herthelius, B.6
  • 87
    • 18744377731 scopus 로고    scopus 로고
    • Recurrence of hemolytic uremic syndrome after live related renal transplantation associated with subsequent de novo disease in the donor
    • Donne RL, Abbs I, Barany P, Elinder CG, Little M, Conlon P, et al. Recurrence of hemolytic uremic syndrome after live related renal transplantation associated with subsequent de novo disease in the donor. Am J Kidney Dis 2002;40(6):E22.
    • (2002) Am J Kidney Dis , vol.40 , Issue.6
    • Donne, R.L.1    Abbs, I.2    Barany, P.3    Elinder, C.G.4    Little, M.5    Conlon, P.6
  • 88
    • 84870534251 scopus 로고    scopus 로고
    • Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation
    • doi: 10.1111/j.1600-6143.2012.04252.x. [Epub ahead of print]
    • Zuber J, Quintrec ML, Krid S, Bertoye C, Gueutin V, Lahoche A, et al. Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation. Am J Transplant 2012 Sep 7. doi: 10.1111/j.1600-6143.2012.04252.x. [Epub ahead of print].
    • Am J Transplant 2012 Sep 7
    • Zuber, J.1    Quintrec, M.L.2    Krid, S.3    Bertoye, C.4    Gueutin, V.5    Lahoche, A.6
  • 89
    • 84863208524 scopus 로고    scopus 로고
    • Renal Transplantation Under Prophylactic Eculizumab in Atypical Hemolytic Uremic Syndrome with CFH/CFHR1 Hybrid Protein
    • Krid S, Roumenina L, Beury D, Charbit M, Boyer O, Fremeaux-Bacchi V, et al. Renal Transplantation Under Prophylactic Eculizumab in Atypical Hemolytic Uremic Syndrome with CFH/CFHR1 Hybrid Protein. Am J Transplant 2012;12(7):1938-44.
    • (2012) Am J Transplant , vol.12 , Issue.7 , pp. 1938-1944
    • Krid, S.1    Roumenina, L.2    Beury, D.3    Charbit, M.4    Boyer, O.5    Fremeaux-Bacchi, V.6
  • 90
    • 84867993256 scopus 로고    scopus 로고
    • Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
    • Zuber J, Fakhouri F, Roumenina LT, Loirat C, Fremeaux-Bacchi V. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies. Nat Rev Nephrol 2012;8(11):643-57.
    • (2012) Nat Rev Nephrol , vol.8 , Issue.11 , pp. 643-657
    • Zuber, J.1    Fakhouri, F.2    Roumenina, L.T.3    Loirat, C.4    Fremeaux-Bacchi, V.5
  • 91
    • 65649106258 scopus 로고    scopus 로고
    • Liverkidney transplantation to cure atypical hemolytic uremic syndrome
    • Saland JM, Ruggenenti P, Remuzzi G; Consensus Study G. Liverkidney transplantation to cure atypical hemolytic uremic syndrome. J Am Soc Nephrol 2009;20(5):940-9.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.5 , pp. 940-949
    • Saland, J.M.1    Ruggenenti, P.2    Remuzzi, G.3
  • 92
    • 37549018997 scopus 로고    scopus 로고
    • Successful liver-kidney transplantation in two children with aHUS caused by a mutation in complement factor H
    • Jalanko H, Peltonen S, Koskinen A, Puntila J, Isoniemi H, Holmberg C, et al. Successful liver-kidney transplantation in two children with aHUS caused by a mutation in complement factor H. Am J Transplant 2008;8(1):216-21.
    • (2008) Am J Transplant , vol.8 , Issue.1 , pp. 216-221
    • Jalanko, H.1    Peltonen, S.2    Koskinen, A.3    Puntila, J.4    Isoniemi, H.5    Holmberg, C.6
  • 94
    • 77956135217 scopus 로고    scopus 로고
    • Successful isolated liver transplantation in a child with atypical hemolytic uremic syndrome and a mutation in complement factor H
    • Haller W, Milford DV, Goodship TH, Sharif K, Mirza DF, McKiernan PJ. Successful isolated liver transplantation in a child with atypical hemolytic uremic syndrome and a mutation in complement factor H. Am J Transplant 2010;10(9):2142-7.
    • (2010) Am J Transplant , vol.10 , Issue.9 , pp. 2142-2147
    • Haller, W.1    Milford, D.V.2    Goodship, T.H.3    Sharif, K.4    Mirza, D.F.5    McKiernan, P.J.6
  • 95
    • 79959342153 scopus 로고    scopus 로고
    • Successful simultaneous liver-kidney transplant in an adult with atypical hemolytic uremic syndrome associated with a mutation in complement factor H
    • Wilson C, Torpey N, Jaques B, Strain L, Talbot D, Manas D, et al. Successful simultaneous liver-kidney transplant in an adult with atypical hemolytic uremic syndrome associated with a mutation in complement factor H. Am J Kidney Dis 2011;58(1):109-12.
    • (2011) Am J Kidney Dis , vol.58 , Issue.1 , pp. 109-112
    • Wilson, C.1    Torpey, N.2    Jaques, B.3    Strain, L.4    Talbot, D.5    Manas, D.6
  • 96
    • 84895850818 scopus 로고    scopus 로고
    • The successful treatment of transplant-associated thrombotic microangiopathy with eculuzimab [P632]
    • Murphy T, Maw D, Besser M, Sureda S. The successful treatment of transplant-associated thrombotic microangiopathy with eculuzimab [P632]. Bone Marrow Transplant 2012;47(Suppl 1):S1-527.
    • (2012) Bone Marrow Transplant , vol.47 , Issue.SUPPL. 1
    • Murphy, T.1    Maw, D.2    Besser, M.3    Sureda, S.4
  • 98
    • 79959390955 scopus 로고    scopus 로고
    • Eculizumab for the treatment of de novo thrombotic microangiopathy post simultaneous pancreas-kidney transplantation-a case report
    • Chandran S, Baxter-Lowe L, Olson JL, Tomlanovich SJ, Webber A. Eculizumab for the treatment of de novo thrombotic microangiopathy post simultaneous pancreas-kidney transplantation-a case report. Transplant Proc 2011;43(5):2097-101.
    • (2011) Transplant Proc , vol.43 , Issue.5 , pp. 2097-2101
    • Chandran, S.1    Baxter-Lowe, L.2    Olson, J.L.3    Tomlanovich, S.J.4    Webber, A.5
  • 99
    • 84863981911 scopus 로고    scopus 로고
    • Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count
    • Dorresteijn EM, van de Kar NC, Cransberg K. Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count. Pediatr Nephrol 2012;27(7):1193-5.
    • (2012) Pediatr Nephrol , vol.27 , Issue.7 , pp. 1193-1195
    • Dorresteijn, E.M.1    van de Kar, N.C.2    Cransberg, K.3
  • 100
    • 84898865896 scopus 로고    scopus 로고
    • Eculizumab in atypical haemolytic-uraemic syndrome allows cessation of plasma exchange and dialysis
    • Kim JJ, Waller SC, Reid CJ. Eculizumab in atypical haemolytic-uraemic syndrome allows cessation of plasma exchange and dialysis. Clin Kidney J 2012;5(1):34-6.
    • (2012) Clin Kidney J , vol.5 , Issue.1 , pp. 34-36
    • Kim, J.J.1    Waller, S.C.2    Reid, C.J.3
  • 103
    • 77950955452 scopus 로고    scopus 로고
    • Efficacy of eculizumab in the treatment of recurrent atypical hemolytic-uremic syndrome after renal transplantation
    • Larrea CF, Cofan F, Oppenheimer F, Campistol JM, Escolar G, Lozano M. Efficacy of eculizumab in the treatment of recurrent atypical hemolytic-uremic syndrome after renal transplantation. Transplantation 2010;89(7):903-4.
    • (2010) Transplantation , vol.89 , Issue.7 , pp. 903-904
    • Larrea, C.F.1    Cofan, F.2    Oppenheimer, F.3    Campistol, J.M.4    Escolar, G.5    Lozano, M.6
  • 104
    • 84863724130 scopus 로고    scopus 로고
    • Eculizumab for the treatment of two recurrences of atypical hemolytic uremic syndrome in a kidney allograft
    • Alachkar N, Bagnasco SM, Montgomery RA. Eculizumab for the treatment of two recurrences of atypical hemolytic uremic syndrome in a kidney allograft. Transpl Int 2012;25(8):e93-5.
    • (2012) Transpl Int , vol.25 , Issue.8
    • Alachkar, N.1    Bagnasco, S.M.2    Montgomery, R.A.3


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