Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome

Pediatric Nephrology

Volumn 24, Issue 4, 2009, Pages 687-696

  Ariceta, Gema ^a   Besbas, Nesrin ^b   Johnson, Sally ^c   Karpman, Diana ^d   Landau, Daniel ^e   Licht, Christoph ^f   Loirat, Chantal ^g   Pecoraro, Carmine ^h   Taylor, C Mark ^c   Van der Kar, Nicole ⁱ   VandeWalle, Johan ^j   Zimmerhackl, Lothar B ^k  

^a HOSPITAL DE CRUCES   (Spain)

^b HACETTEPE UNIVERSITY   (Turkey)

^c BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^d LUND UNIVERSITY   (Sweden)

^e BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^f HOSPITAL FOR SICK CHILDREN   (Canada)

^g HÔPITAL ROBERT DEBRÉ   (France)

^h SANTOBONO PAUSILIPON CHILDREN S HOSPITAL   (Italy)

ⁱ RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^j GHENT UNIVERSITY HOSPITAL   (Belgium)

^k Universitatsklinik fur Kinder und Jugendheilkunde Innsbruck   (Austria)

more..

Author keywords

A disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13); Atypical HUS; Complement C3; Complement factor B; Complement factor H; Complement factor I; Enterohemorrhagic Escherichia coli; Hemolytic uremic syndrome; Membrane co factor protein MCP (CD46); Plasmapheresis; Thrombotic thrombocytopenic purpura

Indexed keywords

ACUTE KIDNEY FAILURE; ANEMIA; BLOOD PRESSURE MONITORING; CHILD; CLINICAL EFFECTIVENESS; CLINICAL PROTOCOL; COMPLEMENT DISORDER; CONSENSUS DEVELOPMENT; EDITORIAL; ENTEROHEMORRHAGIC ESCHERICHIA COLI; HEMOLYTIC UREMIC SYNDROME; HUMAN; INFECTION CONTROL; KIDNEY FUNCTION; OUTCOMES RESEARCH; PLASMAPHERESIS; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGNOSIS; PROTEINURIA; RELAPSE; REMISSION; RISK FACTOR; SHIGELLA DYSENTERIAE; SHIGELLOSIS; STREPTOCOCCUS PNEUMONIAE;

CHILD; CHILD, PRESCHOOL; DIARRHEA; HEMOLYTIC-UREMIC SYNDROME; HUMANS; INFANT; INFANT, NEWBORN; OCCULT BLOOD; PLASMAPHERESIS;

EID: 61549117207     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-008-0964-1     Document Type: Editorial

References (33)

1. Besbas N, Karpman D, Landau D, Loirat C, Proesmans W, Remuzzi G, Rizzoni G, Taylor CM, Van de Kar N, Zimmerhackl LB, European Paediatric Research Group for HUS (2006) A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders. Kidney Int 70:423-431
2. Allford SL, Hunt BJ, Rose P, Machin SJ, Haemostasis and Thrombosis Task Force, British Committee for Standards in Haematology (2003) Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias. Br J Haematol 120:556-573
3. Novak RW, Martin CR, Orsini EN (1983) Hemolytic-uremic syndrome and T-cryptantigen exposure by neuraminidase-producing pneumococci: An emerging problem? Pediatr Pathol 1:409-413
4. Gerber A, Karch H, Allerberger F, Verweyen HM, Zimmerhackl LB (2002) Clinical course and the role of shiga toxin-producing Escherichia coli infection in the hemolytic-uremic syndrome in pediatric patients, 1997-2000, in Germany and Austria: A prospective study. J Infect Dis 186:493-500
5. Milford DV, Taylor CM, Guttridge B, Hall SM, Rowe B, Kleanthous H (1990) Haemolytic uraemic syndromes in the British Isles 1985-8: Association with verocytotoxin producing Escherichia coli. Part 1: Clinical and epidemiological aspects. Arch Dis Child 65:716-721
6. Fitzpatrick MM, Walters MD, Trompeter RS, Dillon MJ, Barratt TM (1993) Atypical (non-diarrhea-associated) hemolytic-uremic syndrome in childhood. J Pediatr 122:532-537
7. Bonser RS, Adu D, Franklin I, McMaster P (1984) Cyclosporin-induced haemolytic uraemic syndrome in liver allograft recipient. Lancet 2:1337
8. Moake JL, Byrnes JJ (1996) Thrombotic microangiopathies associated with drugs and bone marrow transplantation. Hematol Oncol Clin North Am 10:485-497
9. Abraham KA, Little MA, Dorman AM, Walshe JJ (2000) Hemolytic-uremic syndrome in association with both cyclosporine and tacrolimus. Transpl Int 13:443-447
10. Hogan MC, Gloor JM, Uhl JR, Cockerill FR, Milliner DS (2001) Two cases of non-O157:H7 Escherichia coli hemolytic uremic syndrome caused by urinary tract infection. Am J Kidney Dis 38:E22
11. Bielaszewska M (2007) Shiga toxin-mediated hemolytic uremic syndrome: time to change the diagnostic paradigm? PLoS ONE 2:e1024
12. Pradel N, Livrelli V, De Champs C, Palcoux JB, Reynaud A, Scheutz F, Sirot J, Joly B, Forestier C (2000) Prevalence and characterization of Shiga toxin-producing Escherichia coli isolated from cattle, food, and children during a one-year prospective study in France. J Clin Microbiol 38:1023-1031
13. Saunders RE, Goodship TH, Zipfel PF, Perkins SJ (2006) An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations. Hum Mutat 27:21-30
14. Sellier-Leclerc AL, Fremeaux-Bacchi V, Dragon-Durey MA, Macher MA, Niaudet P, Guest G, Boudailliez B, Bouissou F, Deschenes G, Gie S, Tsimaratos M, Fischbach M, Morin D, Nivet H, Alberti C, Loirat C, French Society of Pediatric Nephrology (2007) Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome. J Am Soc Nephrol 18:2392-2400
15. Caprioli J, Noris M, Brioschi S, Pianetti G, Castelletti F, Bettinaglio P, Mele C, Bresin E, Cassis L, Gamba S, Porrati F, Bucchioni S, Monteferrante G, Fang CJ, Liszewski MK, Kavanagh D, Atkinson JP, Remuzzi G, International Registry of Recurrent and Familial HUS/TTP (2006) Genetics of HUS: The impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood 108:1267-1279
16. Michon B, Moghrabi A, Winikoff R, Barrette S, Bernstein ML, Champagne J, David M, Duval M, Hume HA, Robitaille N, Bélisle A, Champagne MA (2007) Complications of apheresis in children. Transfusion 47:1837-1842
17. O'Shaughnessy DF, Atterbury C, Bolton Maggs P, Murphy M, Thomas D, Yates S, Williamson LM, British Committee for Standards in Haematology, Blood Transfusion Task Force (2004) Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol 126:11-28
18. Stratton JD, Warwicker P (2002) Successful treatment of factor H-related haemolytic uraemic syndrome. Nephrol Dial Transplant 17:684-685
19. Davin JC, Olie KH, Verlaak R, Horuz F, Florquin S, Weening JJ, Groothoff JW, Strain L, Goodship TH (2006) Complement factor H-associated atypical hemolytic uremic syndrome in monozygotic twins: Concordant presentation, discordant response to treatment. Am J Kidney Dis 47:e27-e30
20. Filler G, Radhakrishnan S, Strain L, Hill A, Knoll G, Goodship TH (2004) Challenges in the management of infantile factor H associated hemolytic uremic syndrome. Pediatr Nephrol 19:908-911
21. Licht C, Weyersberg A, Heinen S, Stapenhorst L, Devenge J, Beck B, Waldherr R, Kirschfink M, Zipfel PF, Hoppe B (2005) Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15. Am J Kidney Dis 45:415-421
22. Nathanson S, Fremeaux-Bacchi V, Deschenes G (2001) Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency. Pediatr Nephrol 16:554-556
23. Jackson LV, Thalange NK, Cole TJ (2007) Blood pressure centiles for Great Britain. Arch Dis Child 92:298-303
24. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents (1996) Update on the 1987 Task Force report on high blood pressure in children and adolescents: A working group report from the National High Blood Pressure Education Program. Pediatrics 98:649-658
25. Rock GMD (2005) The management of thrombotic thrombocytopenic purpura in 2005. Semin Thromb Hemost 31:709-716
26. Landau D, Shalev H, Levy-Finer G, Polonsky A, Segev Y, Katchko L (2001) Familial hemolytic uremic syndrome associated with complement factor H deficiency. J Pediatr 138:412-417
27. Nathanson S, Ulinski T, Frémeaux-Bacchi V, Deschénes G (2006) Secondary failure of plasma therapy in factor H deficiency. Pediatr Nephrol 21:1769-1771
28. Zurowska A, Zaluska-Lesniewska I, Hladny-Czerska W (2006) Successful prophylactic plasma infusions in recurrent atypical hemolytic-uremic syndrome. Przegl Lek 63 [Suppl 3]:223-225
29. Cho HY, Lee BS, Moon KC, Ha IS, Cheong HI, Choi Y (2007) Complete factor H deficiency-associated atypical hemolytic uremic syndrome in a neonate. Pediatr Nephrol 22:874-880
30. Gerber A, Kirchhoff-Moradpour AH, Obieglo S, Brandis M, Kirschfink M, Zipfel PF, Goodship JA, Zimmerhackl LB (2003) Successful (?) therapy of hemolytic-uremic syndrome with factor H abnormality. Pediatr Nephrol 18:952-955
31. Dragon-Durey MA, Loirat C, Cloarec S, Macher MA, Blouin J, Nivet H, Weiss L, Fridman WH, Frémeaux-Bacchi V (2005) Anti-factor H autoantibodies associated with atypical hemolytic uremic syndrome. J Am Soc Nephrol 16:555-563
32. Goicoechea de Jorge E, Harris CL, Esparza-Gordillo J, Carreras L, Arranz EA, Garrido CA, López-Trascasa M, Sánchez-Corral P, Morgan BP, Rodríguez de Córdoba S (2007) Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proc Natl Acad Sci USA 104:240-245
33. Jokiranta TS, Zipfel PF, Fremeaux-Bacchi V, Taylor CM, Goodship TJ, Noris M (2007) Where next with atypical hemolytic uremic syndrome? Mol Immunol 44:3889-3900