Myocardial infarction is a complication of factor H-associated atypical HUS

Nephrology Dialysis Transplantation

Volumn 25, Issue 6, 2010, Pages 2028-2032

  Sallée, Marion ^a   Daniel, Laurent ^b   Piercecchi, Marie Dominique ^b   Jaubert, Dominique ^a   Fremeaux Bacchi, Veronique ^c   Berland, Yvon ^a   Burtey, Stephane ^a  

^a HÔPITAL DE LA CONCEPTION   (France)

^b TIMONE HOSPITAL   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

Atypical haemolytic uraemic syndrome; Coronary thrombotic microangiopathy; Factor H mutation; Sudden death

Indexed keywords

ADRENALIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; CORTICOSTEROID; CREATININE; LACTATE DEHYDROGENASE; TROPONIN C; TROPONIN I; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ACUTE HEART INFARCTION; ACUTE KIDNEY FAILURE; ADULT; ARTICLE; ATYPICAL HEMOLYTIC UREMIC SYNDROME; AUTOPSY; CARDIOVASCULAR RISK; CASE REPORT; CLINICAL FEATURE; CORONARY THROMBOTIC MICROANGIOPATHY; CORTICOSTEROID THERAPY; CREATININE BLOOD LEVEL; DIALYSIS; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DRUG PULSE THERAPY; ECHOGRAPHY; ELECTROCARDIOGRAPHY; ERYTHROCYTE TRANSFUSION; FATALITY; FEMALE; GENE MUTATION; HEART TAMPONADE; HEMOLYTIC ANEMIA; HEMOLYTIC UREMIC SYNDROME; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; KIDNEY BIOPSY; LACTATE DEHYDROGENASE BLOOD LEVEL; MICROANGIOPATHY; PERICARDIOCENTESIS; PLASMAPHERESIS; PRIORITY JOURNAL; SUDDEN DEATH; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA;

ADULT; AMINO ACID SUBSTITUTION; COMPLEMENT FACTOR H; FATAL OUTCOME; FEMALE; HEMOLYTIC-UREMIC SYNDROME; HUMANS; MUTATION, MISSENSE; MYOCARDIAL INFARCTION;

EID: 77953008442     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfq160     Document Type: Article

References (26)

1. Noris M, Remuzzi G. Atypical haemolytic-uremic syndrome. N Engl J Med 2009; 361: 1676-1687
2. Noris M, Ruggenenti P, Perna A et al. Hypocomplementemia discloses genetic predisposition to haemolytic uremic syndrome and thrombotic thrombocytopenic purpura: role of factor H abnormalities. Italian Registry of Familial and Recurrent Haemolytic Uremic Syn-drome/Thrombotic Thrombocytopenic Purpura. J Am Soc Nephrol 1999; 10: 281-293
3. Perez-Caballero D, Gonzalez-Rubio C, Gallardo ME et al. Clustering of missense mutations in the C-terminal region of factor H in atypical haemolytic uremic syndrome. Am J Hum Genet 2001; 68: 478-484
4. Kavanagh D, Richards A, Noris M et al. Characterization of mutations in complement factor I (CFI) associated with haemolytic uremic syndrome. Mol Immunol 2008; 45: 95-105 (Pubitemid 47336973)
5. Fremeaux-Bacchi V, Kemp EJ, Goodship JA et al. The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts. J Med Genet 2005; 42: 852-856
6. Delvaeye M, Noris M, De Vriese A et al. Thrombomodulin mutations in atypical haemolytic-uremic syndrome. N Engl J Med 2009; 361: 345-357
7. Goicoechea de Jorge E, Harris CL, Esparza-Gordillo J et al. Gain-of-function mutations in complement factor B are associated with atypical haemolytic uremic syndrome. Proc Natl Acad Sci USA 2007; 104: 240-245
8. Fremeaux-Bacchi V, Miller EC, Liszewski MK et al. Mutations in complement C3 predispose to development of atypical haemolytic uremic syndrome. Blood 2008; 112: 4948-4952
9. Piercecchi-Marti MD, Lepidi H, Leonetti G, Vire O, Cianfarani F, Pellissier JF. Immunostaining by complement C9: a tool for early diagnosis of myocardial infarction and application in forensic medicine. J Forensic Sci 2001; 46: 328-334
10. McCarthy LJ, Danielson CF, Skipworth EM et al. Myocardial infarction/injury is relatively common at presentation of acute thrombotic thrombocytopenic purpura: the Indiana University experience. Ther Apher 2002; 6: 2-4
11. Matsukawa M, Kaikita K, Soejima K et al. Serial changes in von Willebrand factor-cleaving protease (ADAMTS13) and prognosis after acute myocardial infarction. Am J Cardiol 2007; 100: 758-763
12. Thachil J. The role for adjunctive treatment to plasma exchange in thrombotic thrombocytopenic purpura. Nephrol Dial Transplant 2008; 23: 2701-2702 author reply 2702-2703
13. Hosler GA, Cusumano AM, Hutchins GM. Thrombotic thrombocy-topenic purpura and haemolytic uremic syndrome are distinct pathologic entities. A review of 56 autopsy cases. Arch Pathol Lab Med 2003; 127: 834-839
14. Eckart P, Guillot M, Jokic M et al. Cardiac involvement during classic haemolytic uremic syndrome. Arch Pediatr 1999; 6: 430-433
15. Thayu M, Chandler WL, Jelacic S et al. Cardiac ischemia during hae-molytic uremic syndrome. Pediatr Nephrol 2003; 18: 286-289
16. Nayak SG, Satish R, Gokulnath. An unusual toxic cause of haemo-lytic-uremic syndrome. J Toxicol Sci 2007; 32: 197-199
17. Abu-Arafeh I, Gray E, Youngson G et al. Myocarditis and haemolytic uraemic syndrome. Arch Dis Child 1995; 72: 46-47
18. Thomas NJ, Messina JJ, DeBruin WJ et al. Cardiac failure in haemo-lytic uremic syndrome and rescue with extracorporeal life support. Pediatr Cardiol 2005; 26: 104-106
19. Askiti V, Hendrickson K, Fish AJ et al. Troponin I levels in a hae-molytic uremic syndrome patient with severe cardiac failure. Pediatr Nephrol 2004; 19: 345-348
20. Tobias JD. Haemolytic-uremic syndrome and myocardial dysfunction in a 9-month-old boy. Paediatr Anaesth 2007; 17: 584-587
21. Mohammed J, Filler G, Price A et al. Cardiac tamponade in diarrhoea-positive haemolytic uraemic syndrome. Nephrol Dial Transplant 2009; 24: 679-681
22. Walker AM, Benson LN, Wilson GJ et al. Cardiomyopathy: a late complication of haemolytic uremic syndrome. Pediatr Nephrol 1997; 11: 221-222
23. Poulton J, Taylor CM, De Giovanni JV. Dilated cardiomyopathy associated with haemolytic uraemic syndrome. Br Heart J 1987; 57: 181-183
24. Birk PE, Chakrabarti S, Lacson AG et al. Cardiac tamponade as a terminal event in the haemolytic uremic syndrome in childhood. Pediatr Nephrol 1994; 8: 754-755
25. Leray H, Mourad G, du Cailar G et al. Dilated cardiomyopathy during post-partum haemolytic and uremic syndrome (HUS). Nephrologie 1991; 12: 237-240
26. Patschan D, Witzke O, Duhrsen U et al. Acute myocardial infarction in thrombotic microangiopathies\clinical characteristics, risk factors and outcome. Nephrol Dial Transplant 2006; 21: 1549-1554